Faculty Profiles - GUO Yusong | The Hong Kong University of Science and Technology

Yusong GUO
郭玉松

PhD in Biological Sciences
Carnegie Mellon University, 2008

Associate Professor
Division of Life Science

UG Programs Coordinator (Life Science)

(852) 3469 2492
guoyusong@ust.hk
Room 5530
Personal Web

ORCID

0000-0002-5539-599X

ResearcherID

C-7705-2011

Scopus ID

55765694600

Research Interest Publications Projects Teaching Assignment RPG Supervision Space used

Research Interest

Cell biology
Cellular and molecular mechanisms
Intracellular protein trafficking
Membrane trafficking

Publications

All Years 36 2023 4 2022 4 2021 6 2020 4 2019 3 2018 2 2017 13

2023 4

Continuous-flow label-free size fractionation of extracellular vesicles through electrothermal fluid rolls and dielectrophoresis synergistically integrated in a microfluidic device

Lab on a Chip, March 2023
Bu, Yang; Wang, Jinhui; Ni, Sheng; Guo, Yusong; Yobas, Levent
Article

In Vitro Reconstitution of COPII Vesicles from Arabidopsis Thaliana Suspension-Cultured Cells

Nature Protocols, v. 18, 4 January 2023, p. 810-830
Li, Baiying; Zeng, Yonglun; Lo, Sze Wan; Guo, Yusong; Jiang, Liwen
Article

The clathrin adaptor complex-1 and Rab12 regulate post-Golgi trafficking of wild-type epidermal growth factor receptor.

Journal of Biological Chemistry, v. 299, (3), March 2023, article number 102979
Wang, Jinhui; Lau, Pik Ki; Li, Chun Wa; Guo, Yusong
Article

Reconstitution of Vesicle Budding from the TGN and Immunoisolation of Vesicles Enriched with a Specific Cargo Client

Golgi: Methods and Protocols / edited by Yanzhuang Wang, Vladimir V Lupashin, Todd R. Graham. New York, USA : Springer, 2023, p. 289-302, Book series: Methods in Molecular Biology, v. 2557
Wang, Mo; Wang, Jinhui; Guo, Yusong
Book chapter

2022 4

A SURF4-to-Proteoglycan Relay Mechanism that Mediates the Sorting and Secretion of a Tagged Variant of Sonic Hedgehog

Proceedings of the National Academy of Sciences of the United States of America, v. 119, (11), March 2022, article number e2113991119
Tang, Xiao; Chen, Rong; Mesias, Vince St. Dollente; Wang, Tingxuan; Wang, Ying; Poljak, Kristina; Fan, Xinyu; Miao, Hanchi; Hu, Junjie; Zhang, Liang; Huang, Jinqing; Yao, Shuhuai; Miller, Elizabeth A.; Guo, Yusong
Article

ADP-Ribosylation Factor Family of Small GTP-Binding Proteins: Their Membrane Recruitment, Activation, Crosstalk and Functions

Frontiers in Cell and Developmental Biology, v. 10 , February 2022, article number 813353
Li, Tiantian; Guo, Yusong
Article

Export of polybasic motif-containing secretory proteins BMP8A and SFRP1 from the endoplasmic reticulum is regulated by surfeit locus protein 4

Journal of Biological Chemistry, v. 298, (12), December 2022, article number 102687
Tang, Xiao; Wang, Tingxuan; Guo, Yusong
Article

Moderate Binding between Two SARS-CoV-2 Protein Segments and α-Synuclein Alters Its Toxic Oligomerization Propensity Differently

The Journal of Physical Chemistry Letters, v. 13, (45), November 2022, p. 10642-10648
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Liu, Wei; Guo, Yusong; Huang, Jinqing
Article

2021 6

A distinct giant coat protein complex II vesicle population in Arabidopsis thaliana

Nature Plant, v. 7, (10), October 2021, p. 1335-1346
Li, Baiying; Zeng, Yonglun; Cao, Wenhan; Zhang, Wenxin; Cheng, Lixin; Yin, Haidi; Wu, Qian; Wang, Xiangfeng; Huang, Yan; Lau, Wilson Chun Yu; Yao, Zhong-Ping; Guo, Yusong; Jiang, Liwen
Article

An in vitro vesicle formation assay reveals cargo clients and factors that mediate vesicular trafficking

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (35), August 2021, article number e2101287118
Huang, Yan; Yin, Haidi; Li, Baiying; Wu, Qian; Liu, Yang; Poljak, Kristina; Maldutyte, Julija; Tang, Xiao; Wang, Mo; Wu, Zhixiao; Miller, Elizabeth A.; Jiang, Liwen; Yao, Zhong-Ping; Guo, Yusong
Article

Effective ACE2 peptide-nanoparticle conjugation and its binding with the SARS-Cov-2 RBD quantified by dynamic light scattering

Chemical Communications, v. 57, (57), July 2021, p. 6979-6982
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing
Article

Endoplasmic Reticulum Composition And Form: Proteins In And Out

Current Opinion in Cell Biology, v. 71, August 2021, p. 1-6
Sun, Sha; Tang, Xiao; Guo, Yusong; Hu, Junjie
Article

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation

Science Advances, v. 7, (20), May 2021, article number eabg2099
Feng, Di; Wang, Jin; Yang, Wei; Li, Jingyu; Lin, Xiaochen; Zha, Fangzi; Wang, Xiaolu; Ma, Luyao; Choi, Nga Ting; Mii, Yusuke; Takada, Shinji; Huen, Michael S. Y.; Guo, Yusong; Zhang, Liang; Gao, Bo
Article

Truncated Angiotensin-Converting Enzyme-2 peptide conjugated nanoparticles as an efficient, specific, and long-lasting antiviral platform for SARS-CoV-2

Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing
Conference paper

2020 4

Cell-free Reconstitution of the Packaging of Cargo Proteins into Vesicles at the trans Golgi Network

Bio-protocol, v. 10, (5), March 2020, article number e3537
Tang, Xiao; Yang, Feng; Guo, Yusong
Article

Dynamically Tunable, Macroscopic Molecular Networks Enabled by Cellular Synthesis of 4-Arm Star-like Proteins

Matter, v. 2, (1), January 2020, p. 233-249
Yang, Zhongguang; Yang, Yang; Wang, Mo; Wang, Tingting; Fok, Hong Kiu Francis; Jiang, Bojing; Xiao, Wendi; Kou, Songzi; Guo, Yusong; Yan, Yan; Deng, Xin; Zhang, Wen-Bin; Sun, Fei
Article

Molecular Mechanisms That Regulate Export of the Planar Cell-Polarity Protein Frizzled-6 Out of the Endoplasmic Reticulum

Journal of Biological Chemistry, v. 295, (27), July 2020, p. 8972-8987
Tang, Xiao; Zhang, Lina; Ma, Tianji; Wang, Mo; Li, Baiying; Jiang, Liwen; Yan, Yan; Guo, Yusong
Article

The amphipathic helices of Arfrp1 and Arl14 are sufficient to determine subcellular localizations

Journal of Biological Chemistry, v. 295, (49), December 2020, p. 16643-16654
Yang, Feng; Li, Tiantian; Peng, Ziqing; Liu, Yang; Guo, Yusong
Article

2019 3

Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum

Proceedings of the National Academy of Sciences of the United States of America, v. 116, (28), June 2019, p. 14029-14038
Niu, Liling; Ma, Tianji; Yang, Feng; Yan, Bing; Tang, Xiao; Yin, Haidi; Wu, Qian; Huang, Yan; Yao, Zhong-Ping; Wang, Jifeng; Guo, Yusong; Hu, Junjie
Article

The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking

Development, v. 146, (13), June 2019, article number dev174615
Mao, Ying; Tu, Renjun; Huang, Yan; Mao, Decai; Yang, Zhihao; Lau, Pik Ki; Wang, Jinhui; Ni, Jianquan; Guo, Yusong; Xie, Ting
Article

Visualization of Protein Sorting at the Trans-Golgi Network and Endosomes Through Super-Resolution Imaging

Frontiers in Cell Development Biology, v. 7, September 2019, article number 181
Huang, Yan; Ma, Tianji; Lau, Pik Ki; Wang, Jinhui; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Guo, Yusong
Article

2018 2

A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network

Journal of Biological Chemistry, v. 293, (22), June 2018, p. 8410-8427
Ma, Tianji; Li, Baiying; Wang, Ryan; Lau, Pik Ki; Huang, Yan; Jiang, Liwen; Schekman, Randy; Guo, Yusong
Article

Intracellular trafficking of planar cell polarity proteins

Frontiers in Biology, v. 13, (6), December 2018, p. 395-405
Huang, Yan; Ma, Tianji; Guo, Yusong
Article

2017 1

An Overview of Protein Secretion in Yeast and Animal Cells

Plant Protein Secretion / New York, US : Humana Press, New York, NY, 2017, p. 1-17, Part of the Methods in Molecular Biology book series (MIMB, v. 1662)
Guo, Yusong; Yang, Feng; Tang, Xiao
Book chapter

2016 1

Statistical analysis and probabilistic verification of stress-induced signalling pathways

International Journal of Data Mining and Bioinformatics, v. 14, (2), February 2016, p. 120-138
Ma, Yinjiao; Feng, Lu; Guo, Yusong; Gong, Haijun
Article

2014 1

Protein Sorting at the trans-Golgi Network

Annual Review of Cell and Developmental Biology, v. 30, October 2014, p. 169-206
Guo, Yusong; Sirkis, Daniel W.; Schekman, Randy
Article

2013 2

A novel GTP-binding protein-adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

eLife, v. 2013, (2), January 2013, article number e00160
Guo, Yusong; Zanetti, Giulia; Schekman, Randy W.
Article

Binding of the vesicle docking protein p115 to the GTPase Rab1b regulates membrane recruitment of the COPI vesicle coat

Cellular Logistics, v. 3, (1), January 2014, p. 1-10
Guo, Yusong; Linstedt, Adam D.
Article

2010 1

Discrete, continuous, and stochastic models of protein sorting in the Golgi apparatus

Physical Review E, v. 81, (1), January 2010, article number 011914
Gong, Haijun; Guo, Yusong; Linstedt, Adam; Schwartz, Russell
Article

2009 1

Active mask segmentation of fluorescence images

IEEE Transactions on Image Processing, v. 18, (8), August 2009, p. 1817-1829
Srinivasa, Gowri; Fickus, Matthew C.; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena V.
Conference paper

2008 2

Coat-tether interaction in Golgi organization

v. 19, Issue 7, July 2008, p. 2830-2843
Guo, Yusong; Punj, Vasu; Sengupta, Debrup; Linstedt, Adam D.
Article

Active mask segmentation for the cell-volume computation and Golgi-body segmentation of hela cell images

2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI\2008, Article number 4541004, Pages 348-351
Srinivasa, Gowri; Fickus, Matthew C.; Gonzalez-Rivero, Manuel N.; Hsieh, Sarah Yichia; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena V.
Conference paper

2006 1

COPII-Golgi protein interactions regulate COPII coat assembly and Golgi size

Journal of Cell Biology, v. 174, Issue 1, 3 July 2006, p. 53-63
Guo, Yusong; Linstedt, Adam D.
Article

2004 2

A Chinese herbal medicine Ermiao wan reduces serum uric acid level and inhibits liver xanthine dehydrogenase and xanthine oxidase in mice

Journal of Ethnopharmacology\ Volume 93, Issue 2-3, August 2004, Pages 325-330
Kong, Lingdong; Yang, Chen; Ge, Fei; Wang, Haidong; Guo, Yusong
Article

Antidepressant Evaluation of Polysaccharides from a Chinese Herbal Medicine Banxia-houpu Decoction

Phytotherapy Research, v. 18, (3), March 2004, p. 204-207
Guo, Yusong; Kong, Lingdong; Wang, Yemin; Huang, Zhiqi
Article

2002 1

Effects of aqueous extract in herba of Lysimachia christinae on hyperuricemia in mice (in Chinese)

27(12): pp.939-941 & 944
Wang Hai-dong; Ge Fei; Guo Yusong; Kong, Ling-dong
Article

Article 3

Continuous-flow label-free size fractionation of extracellular vesicles through electrothermal fluid rolls and dielectrophoresis synergistically integrated in a microfluidic device

Lab on a Chip, March 2023
Bu, Yang; Wang, Jinhui; Ni, Sheng; Guo, Yusong; Yobas, Levent

In Vitro Reconstitution of COPII Vesicles from Arabidopsis Thaliana Suspension-Cultured Cells

Nature Protocols, v. 18, 4 January 2023, p. 810-830
Li, Baiying; Zeng, Yonglun; Lo, Sze Wan; Guo, Yusong; Jiang, Liwen

The clathrin adaptor complex-1 and Rab12 regulate post-Golgi trafficking of wild-type epidermal growth factor receptor.

Journal of Biological Chemistry, v. 299, (3), March 2023, article number 102979
Wang, Jinhui; Lau, Pik Ki; Li, Chun Wa; Guo, Yusong

Book chapter 1

Reconstitution of Vesicle Budding from the TGN and Immunoisolation of Vesicles Enriched with a Specific Cargo Client

Golgi: Methods and Protocols / edited by Yanzhuang Wang, Vladimir V Lupashin, Todd R. Graham. New York, USA : Springer, 2023, p. 289-302, Book series: Methods in Molecular Biology, v. 2557
Wang, Mo; Wang, Jinhui; Guo, Yusong

Article 4

A SURF4-to-Proteoglycan Relay Mechanism that Mediates the Sorting and Secretion of a Tagged Variant of Sonic Hedgehog

Proceedings of the National Academy of Sciences of the United States of America, v. 119, (11), March 2022, article number e2113991119
Tang, Xiao; Chen, Rong; Mesias, Vince St. Dollente; Wang, Tingxuan; Wang, Ying; Poljak, Kristina; Fan, Xinyu; Miao, Hanchi; Hu, Junjie; Zhang, Liang; Huang, Jinqing; Yao, Shuhuai; Miller, Elizabeth A.; Guo, Yusong

ADP-Ribosylation Factor Family of Small GTP-Binding Proteins: Their Membrane Recruitment, Activation, Crosstalk and Functions

Frontiers in Cell and Developmental Biology, v. 10 , February 2022, article number 813353
Li, Tiantian; Guo, Yusong

Export of polybasic motif-containing secretory proteins BMP8A and SFRP1 from the endoplasmic reticulum is regulated by surfeit locus protein 4

Journal of Biological Chemistry, v. 298, (12), December 2022, article number 102687
Tang, Xiao; Wang, Tingxuan; Guo, Yusong

Moderate Binding between Two SARS-CoV-2 Protein Segments and α-Synuclein Alters Its Toxic Oligomerization Propensity Differently

The Journal of Physical Chemistry Letters, v. 13, (45), November 2022, p. 10642-10648
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Liu, Wei; Guo, Yusong; Huang, Jinqing

Article 5

A distinct giant coat protein complex II vesicle population in Arabidopsis thaliana

Nature Plant, v. 7, (10), October 2021, p. 1335-1346
Li, Baiying; Zeng, Yonglun; Cao, Wenhan; Zhang, Wenxin; Cheng, Lixin; Yin, Haidi; Wu, Qian; Wang, Xiangfeng; Huang, Yan; Lau, Wilson Chun Yu; Yao, Zhong-Ping; Guo, Yusong; Jiang, Liwen

An in vitro vesicle formation assay reveals cargo clients and factors that mediate vesicular trafficking

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (35), August 2021, article number e2101287118
Huang, Yan; Yin, Haidi; Li, Baiying; Wu, Qian; Liu, Yang; Poljak, Kristina; Maldutyte, Julija; Tang, Xiao; Wang, Mo; Wu, Zhixiao; Miller, Elizabeth A.; Jiang, Liwen; Yao, Zhong-Ping; Guo, Yusong

Effective ACE2 peptide-nanoparticle conjugation and its binding with the SARS-Cov-2 RBD quantified by dynamic light scattering

Chemical Communications, v. 57, (57), July 2021, p. 6979-6982
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing

Endoplasmic Reticulum Composition And Form: Proteins In And Out

Current Opinion in Cell Biology, v. 71, August 2021, p. 1-6
Sun, Sha; Tang, Xiao; Guo, Yusong; Hu, Junjie

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation

Science Advances, v. 7, (20), May 2021, article number eabg2099
Feng, Di; Wang, Jin; Yang, Wei; Li, Jingyu; Lin, Xiaochen; Zha, Fangzi; Wang, Xiaolu; Ma, Luyao; Choi, Nga Ting; Mii, Yusuke; Takada, Shinji; Huen, Michael S. Y.; Guo, Yusong; Zhang, Liang; Gao, Bo

Conference paper 1

Truncated Angiotensin-Converting Enzyme-2 peptide conjugated nanoparticles as an efficient, specific, and long-lasting antiviral platform for SARS-CoV-2

Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing

Article 4

Cell-free Reconstitution of the Packaging of Cargo Proteins into Vesicles at the trans Golgi Network

Bio-protocol, v. 10, (5), March 2020, article number e3537
Tang, Xiao; Yang, Feng; Guo, Yusong

Dynamically Tunable, Macroscopic Molecular Networks Enabled by Cellular Synthesis of 4-Arm Star-like Proteins

Matter, v. 2, (1), January 2020, p. 233-249
Yang, Zhongguang; Yang, Yang; Wang, Mo; Wang, Tingting; Fok, Hong Kiu Francis; Jiang, Bojing; Xiao, Wendi; Kou, Songzi; Guo, Yusong; Yan, Yan; Deng, Xin; Zhang, Wen-Bin; Sun, Fei

Molecular Mechanisms That Regulate Export of the Planar Cell-Polarity Protein Frizzled-6 Out of the Endoplasmic Reticulum

Journal of Biological Chemistry, v. 295, (27), July 2020, p. 8972-8987
Tang, Xiao; Zhang, Lina; Ma, Tianji; Wang, Mo; Li, Baiying; Jiang, Liwen; Yan, Yan; Guo, Yusong

The amphipathic helices of Arfrp1 and Arl14 are sufficient to determine subcellular localizations

Journal of Biological Chemistry, v. 295, (49), December 2020, p. 16643-16654
Yang, Feng; Li, Tiantian; Peng, Ziqing; Liu, Yang; Guo, Yusong

Article 3

Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum

Proceedings of the National Academy of Sciences of the United States of America, v. 116, (28), June 2019, p. 14029-14038
Niu, Liling; Ma, Tianji; Yang, Feng; Yan, Bing; Tang, Xiao; Yin, Haidi; Wu, Qian; Huang, Yan; Yao, Zhong-Ping; Wang, Jifeng; Guo, Yusong; Hu, Junjie

The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking

Development, v. 146, (13), June 2019, article number dev174615
Mao, Ying; Tu, Renjun; Huang, Yan; Mao, Decai; Yang, Zhihao; Lau, Pik Ki; Wang, Jinhui; Ni, Jianquan; Guo, Yusong; Xie, Ting

Visualization of Protein Sorting at the Trans-Golgi Network and Endosomes Through Super-Resolution Imaging

Frontiers in Cell Development Biology, v. 7, September 2019, article number 181
Huang, Yan; Ma, Tianji; Lau, Pik Ki; Wang, Jinhui; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Guo, Yusong

Article 2

A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network

Journal of Biological Chemistry, v. 293, (22), June 2018, p. 8410-8427
Ma, Tianji; Li, Baiying; Wang, Ryan; Lau, Pik Ki; Huang, Yan; Jiang, Liwen; Schekman, Randy; Guo, Yusong

Intracellular trafficking of planar cell polarity proteins

Frontiers in Biology, v. 13, (6), December 2018, p. 395-405
Huang, Yan; Ma, Tianji; Guo, Yusong

Book chapter 1

An Overview of Protein Secretion in Yeast and Animal Cells

Plant Protein Secretion / New York, US : Humana Press, New York, NY, 2017, p. 1-17, Part of the Methods in Molecular Biology book series (MIMB, v. 1662)
Guo, Yusong; Yang, Feng; Tang, Xiao

Article 1

Statistical analysis and probabilistic verification of stress-induced signalling pathways

International Journal of Data Mining and Bioinformatics, v. 14, (2), February 2016, p. 120-138
Ma, Yinjiao; Feng, Lu; Guo, Yusong; Gong, Haijun

Article 1

Protein Sorting at the trans-Golgi Network

Annual Review of Cell and Developmental Biology, v. 30, October 2014, p. 169-206
Guo, Yusong; Sirkis, Daniel W.; Schekman, Randy

Article 2

A novel GTP-binding protein-adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

eLife, v. 2013, (2), January 2013, article number e00160
Guo, Yusong; Zanetti, Giulia; Schekman, Randy W.

Binding of the vesicle docking protein p115 to the GTPase Rab1b regulates membrane recruitment of the COPI vesicle coat

Cellular Logistics, v. 3, (1), January 2014, p. 1-10
Guo, Yusong; Linstedt, Adam D.

Article 1

Discrete, continuous, and stochastic models of protein sorting in the Golgi apparatus

Physical Review E, v. 81, (1), January 2010, article number 011914
Gong, Haijun; Guo, Yusong; Linstedt, Adam; Schwartz, Russell

Conference paper 1

Active mask segmentation of fluorescence images

IEEE Transactions on Image Processing, v. 18, (8), August 2009, p. 1817-1829
Srinivasa, Gowri; Fickus, Matthew C.; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena V.

Article 1

Coat-tether interaction in Golgi organization

v. 19, Issue 7, July 2008, p. 2830-2843
Guo, Yusong; Punj, Vasu; Sengupta, Debrup; Linstedt, Adam D.

Conference paper 1

Active mask segmentation for the cell-volume computation and Golgi-body segmentation of hela cell images

2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI\2008, Article number 4541004, Pages 348-351
Srinivasa, Gowri; Fickus, Matthew C.; Gonzalez-Rivero, Manuel N.; Hsieh, Sarah Yichia; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena V.

Article 1

COPII-Golgi protein interactions regulate COPII coat assembly and Golgi size

Journal of Cell Biology, v. 174, Issue 1, 3 July 2006, p. 53-63
Guo, Yusong; Linstedt, Adam D.

Article 2

A Chinese herbal medicine Ermiao wan reduces serum uric acid level and inhibits liver xanthine dehydrogenase and xanthine oxidase in mice

Journal of Ethnopharmacology\ Volume 93, Issue 2-3, August 2004, Pages 325-330
Kong, Lingdong; Yang, Chen; Ge, Fei; Wang, Haidong; Guo, Yusong

Antidepressant Evaluation of Polysaccharides from a Chinese Herbal Medicine Banxia-houpu Decoction

Phytotherapy Research, v. 18, (3), March 2004, p. 204-207
Guo, Yusong; Kong, Lingdong; Wang, Yemin; Huang, Zhiqi

Article 1

Effects of aqueous extract in herba of Lysimachia christinae on hyperuricemia in mice (in Chinese)

27(12): pp.939-941 & 944
Wang Hai-dong; Ge Fei; Guo Yusong; Kong, Ling-dong

2017 1

An Overview of Protein Secretion in Yeast and Animal Cells

Plant Protein Secretion / New York, US : Humana Press, New York, NY, 2017, p. 1-17, Part of the Methods in Molecular Biology book series (MIMB, v. 1662)
Guo, Yusong; Yang, Feng; Tang, Xiao
Book chapter

2016 1

Statistical analysis and probabilistic verification of stress-induced signalling pathways

International Journal of Data Mining and Bioinformatics, v. 14, (2), February 2016, p. 120-138
Ma, Yinjiao; Feng, Lu; Guo, Yusong; Gong, Haijun
Article

2014 1

Protein Sorting at the trans-Golgi Network

Annual Review of Cell and Developmental Biology, v. 30, October 2014, p. 169-206
Guo, Yusong; Sirkis, Daniel W.; Schekman, Randy
Article

2013 2

A novel GTP-binding protein-adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

eLife, v. 2013, (2), January 2013, article number e00160
Guo, Yusong; Zanetti, Giulia; Schekman, Randy W.
Article

Binding of the vesicle docking protein p115 to the GTPase Rab1b regulates membrane recruitment of the COPI vesicle coat

Cellular Logistics, v. 3, (1), January 2014, p. 1-10
Guo, Yusong; Linstedt, Adam D.
Article

2010 1

Discrete, continuous, and stochastic models of protein sorting in the Golgi apparatus

Physical Review E, v. 81, (1), January 2010, article number 011914
Gong, Haijun; Guo, Yusong; Linstedt, Adam; Schwartz, Russell
Article

2009 1

Active mask segmentation of fluorescence images

IEEE Transactions on Image Processing, v. 18, (8), August 2009, p. 1817-1829
Srinivasa, Gowri; Fickus, Matthew C.; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena V.
Conference paper

2008 2

Coat-tether interaction in Golgi organization

v. 19, Issue 7, July 2008, p. 2830-2843
Guo, Yusong; Punj, Vasu; Sengupta, Debrup; Linstedt, Adam D.
Article

Active mask segmentation for the cell-volume computation and Golgi-body segmentation of hela cell images

2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI\2008, Article number 4541004, Pages 348-351
Srinivasa, Gowri; Fickus, Matthew C.; Gonzalez-Rivero, Manuel N.; Hsieh, Sarah Yichia; Guo, Yusong; Linstedt, Adam D.; Kovačević, Jelena V.
Conference paper

2006 1

COPII-Golgi protein interactions regulate COPII coat assembly and Golgi size

Journal of Cell Biology, v. 174, Issue 1, 3 July 2006, p. 53-63
Guo, Yusong; Linstedt, Adam D.
Article

2004 2

A Chinese herbal medicine Ermiao wan reduces serum uric acid level and inhibits liver xanthine dehydrogenase and xanthine oxidase in mice

Journal of Ethnopharmacology\ Volume 93, Issue 2-3, August 2004, Pages 325-330
Kong, Lingdong; Yang, Chen; Ge, Fei; Wang, Haidong; Guo, Yusong
Article

Antidepressant Evaluation of Polysaccharides from a Chinese Herbal Medicine Banxia-houpu Decoction

Phytotherapy Research, v. 18, (3), March 2004, p. 204-207
Guo, Yusong; Kong, Lingdong; Wang, Yemin; Huang, Zhiqi
Article

2002 1

Effects of aqueous extract in herba of Lysimachia christinae on hyperuricemia in mice (in Chinese)

27(12): pp.939-941 & 944
Wang Hai-dong; Ge Fei; Guo Yusong; Kong, Ling-dong
Article

Teaching Assignment

2022-23 Spring 12 2022-23 Winter 0 2022-23 Fall 9 2021-22 Summer 3 2021-22 Spring 7 2021-22 Winter 0

LIFS2040	Cell Biology
LIFS4910A	Independent Study
LIFS4960	Biological Science Capstone Project
LIFS4961	Biochemistry and Cell Biology Capstone Project
LIFS4963	Biotechnology Capstone Project
LIFS4981	Biochemistry and Cell Biology Project Research II
LIFS6111R	Life Science Postgraduate Student Seminar
LIFS6117F	Current Topics in Cell Biology
SCIE2500	Guided Study on Research II
SCIE3500	IRE Research Project I
UROP2100I	Undergraduate Research Opportunities Series 2
UROP3100I	Undergraduate Research Opportunities Series 3

ENVS5111	Environmental Health
LIFS4910A	Independent Study
LIFS4960	Biological Science Capstone Project
LIFS4963	Biotechnology Capstone Project
LIFS4971	Biochemistry and Cell Biology Project Research I
LIFS5710	Cellular Regulation
LIFS6170	Special Topics in Molecular, Cell and Developmental Biology
UROP1100H	Undergraduate Research Opportunities Series 1
UROP2100H	Undergraduate Research Opportunities Series 2

UROP1000	Undergraduate Research Opportunities
UROP1100G	Undergraduate Research Opportunities Series 1
UROP3100G	Undergraduate Research Opportunities Series 3

LIFS2040	Cell Biology
LIFS4960	Biological Science Capstone Project
LIFS4963	Biotechnology Capstone Project
LIFS4981	Biochemistry and Cell Biology Project Research II
LIFS6117E	Current Topics in Cell Biology
UROP1100F	Undergraduate Research Opportunities Series 1
UROP2100F	Undergraduate Research Opportunities Series 2

No Teaching Assignments

Research Postgraduate (RPG) Supervision

From January 2020 to December 2023 (As of 28 May 2023)

All Supervisions Current RPGs Graduated RPGs

Current RPGs

Doctor of Philosophy

LI, Anqi
Life Science
XU, Qianwen (co-supervision)
Individualized Interdisciplinary Program (Smart Manufacturing)
JIA, Bowen
Life Science
LI, Tiantian
Life Science
PENG, Ziqing
Life Science
XU, Yingjie
Life Science
LIU, Yang
Life Science
WANG, Mo
Life Science

Master of Philosophy

CONG, Chengge
Life Science
LI, Yihao (co-supervision)
Individualized Interdisciplinary Program (Bioscience and Biomedical Engineering)
LU, Zechen
Life Science
WANG, Tingxuan
Life Science

Graduated RPGs

Doctor of Philosophy

WANG, Jinhui
Life Science( Completed in 2022 )
TANG, Xiao
Life Science( Completed in 2021 )
YANG, Feng
Life Science( Completed in 2021 )
HUANG, Yan
Life Science( Completed in 2020 )

Master of Philosophy

LI, Tiantian
Life Science( Completed in 2021 )
PENG, Ziqing
Life Science( Completed in 2021 )

Projects

From January 2021 to December 2023

All Projects 17 Leading Projects 11 Participating Projects 6

Mechanistic study of the defense systems in marine cyanobacteria against bacteriophage infection

海洋藍藻的抗病毒侵染機制 Participating

RGC - Collaborative Research Fund
Project Team (HKUST)
ZENG Qinglu (Lead)

DANG Shangyu

GUO Yusong

WANG Jiguang
2023 -
Roles of PRRC1 and FAM84B in COPII-mediated endoplasmic reticulum export

PRRC1和FAM84B在COPII介導的內質網輸出中的功能 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)
2023 -
Stem cell-niche interactions in tissue maintenance and engineering

幹細胞與微環境互作在組織維持和組織工程中的應用 Participating

RGC - Theme-based Research Scheme
Project Team (HKUST)
XIE Ting (Lead)

CHEUNG Tom

GUO Yusong

LEUNG Danny Chi Yeu

LIU Kai

MAK Ho Yi

SUN Fei

WEN Zilong

WU Angela Ruohao

WU Zhenguo

YAN Yan
2022 -
Molecular mechanisms regulating the sorting and secretion of sonic hedgehog

探索調控細胞分泌刺猬因子的分子機制 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)
2021 -
Molecular Mechanisms Regulating transport of a planar cell polarity protein, Frizzled6, in the early secretory transport pathway

平面細胞極化蛋白Frizzled6在早期分泌轉運途中運輸的分子機制 Leading

National Natural Science Foundation of China
Project Team (HKUST)
GUO Yusong (Lead)
2021 -
Vacuole Dynamics, Biogenesis and Functions in Plants

植物液泡的動力學，生物起源與功能的研究 Participating

RGC - Collaborative Research Fund
Project Team (HKUST)
GUO Yusong
2021 -
Molecular Mechanisms Regulating the Secretion of Insulin-Like Growth Factor 2 in Myoblast Differentiation and Muscle Regeneration

探索調節胰島素樣生長因子2分泌的分子機制及其在成肌細胞分化和肌肉再生中的功能 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)
2021 -
Activity regulated neuroligin-2 ubiquitination and inhibitory synapse formation.

神經活動調控neuroligin-2泛素化和抑制性突觸形成 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)
2020 -
CDK5RAP2 Autoinhibition as a Control Mechanism of γTuRC-Dependent Microtubule Organization

CDK5RAP2自抑制對依賴於γ-微管蛋白環形複合體的微管組織的調控 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)

QI Robert Zhong
2020 -
Spatial and functional analysis of Arf family proteins and cargo adaptors that regulate protein sorting at the trans Golgi network

調節反式高爾基網絡蛋白質分選的Arf家族蛋白質和貨物適配器的空間和功能分析 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)
2020 - 2022
Molecular Mechanism that regulates transport of epidermal growth factor receptor (EGFR) from the trans Golgi network to the plasma membrane and its implication in EGFR-targeted cancer therapy

表皮生長因子從反式高爾基網絡運輸到細胞膜的分子機制及表皮生長因子受體新靶點的探索 Leading

National Natural Science Foundation of China
Project Team (HKUST)
GUO Yusong (Lead)
2019 - 2022
An in vitro reconstituted vesicle formation assay to systematically investigate the COPII-mediated vesicular transport process

運用體外重建的囊泡形成法系統地研究COPII介導的囊泡運輸過程 Leading

RGC - General Research Fund
Project Team (HKUST)
GUO Yusong (Lead)
2019 - 2021
Molecular mechanisms that regulate export of Epidermal Growth Factor Receptor （EGFR）out of the endoplasmic reticulum and its implication in ERGR-targeted cancer therapy

調控表皮生長因子受體從內質網輸出的分子機制及表皮生長因子受體新靶點的探索 Leading

Shenzhen Science and Technology Innovation Committee
Project Team (HKUST)
GUO Yusong (Lead)
2019 - 2021
Centre for Organelle Biogenesis and Function

細胞器生物合成及功能研究中心 Participating

RGC - Areas of Excellence Scheme
Project Team (HKUST)
GUO Yusong
2018 - 2021
Molecular Mechanisms of Autophagy and Autophagosome in Plants

植物自噬和自噬體的分子機制 Participating

RGC - Collaborative Research Fund
Project Team (HKUST)
GUO Yusong
2018 - 2021
FLRT1 and FLRT3 in auditory hair cells: distinct roles in the development and maintenance of the hair bundle and their interactions with TMC1

FLRT1和FLRT3在聽毛細胞發育及維持聽毛形態中的不同功能以及其與TMC1 的相互作用 Participating

RGC - General Research Fund
Project Team (HKUST)
HUANG Pingbo (Lead)

GUO Yusong
2017 - 2021
Molecular mechanisms that mediate sorting of planar cell polarity signaling receptors at the trans Golgi network

平面細胞極化的信號受體在反面高爾基網絡上被篩選入囊泡的分子機制 Leading

RGC - Early Career Scheme
Project Team (HKUST)
GUO Yusong (Lead)
2016 - 2021

Research Interest

Publications

2023 4

2022 4

2021 6

2020 4

2019 3

2018 2

2017 1

2016 1

2014 1

2013 2

2010 1

2009 1

2008 2

2006 1

2004 2

2002 1

Article 3

Book chapter 1

Article 4

Article 5

Conference paper 1

Article 4

Article 3

Article 2

Book chapter 1

Article 1

Article 1

Article 2

Article 1

Conference paper 1

Article 1

Conference paper 1

Article 1

Article 2

Article 1

2017 1

2016 1

2014 1

2013 2

2010 1

2009 1

2008 2

2006 1

2004 2

2002 1

Teaching Assignment

Research Postgraduate (RPG) Supervision

From January 2020 to December 2023 (As of 28 May 2023)

Current RPGs

Graduated RPGs

Projects

From January 2021 to December 2023

Your browser is out of date!