Metastable biological matter in liquid phase separation

Multiscale Computational Framework for the Liquid–Liquid Phase Separation of Intrinsically Disordered Proteins

Self-adjuvanted L-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses

Construction of Multiphasic Membraneless Organelles towards Spontaneous Spatial Segregation and Directional Flow of Biochemical Reactions

Low-intensity low-frequency ultrasound mediates riboflavin delivery during corneal crosslinking

Peptide-DNA Co-Assembled Nanoparticles as a Nonviral Vector for Gene Delivery with High Transgene Expression

Roles of biomaterials in modulating the innate immune response in ocular therapy

Vaccine delivery by zwitterionic polysaccharide-based hydrogel microparticles showing enhanced immunogenicity and suppressed foreign body responses

A Molecular Dynamics study for salt-mediated size-tunable designer peptide/mRNA co-assembly for efficient cytosol delivery

A multi-scale model for reversible assembly of FUS and irreversible aggregation of its G156E mutant

Modeling of Intrinsically Discorded Protein Mimicking Hybrids for Membraneless Organelles Formation

Modeling of liquid-liquid and liquid-solid phase separation of intrinsically disordered protein mimicking polymer peptide hybrids

Biomaterial design inspired by membraneless organelles

Fusogenic peptide modification to enhance gene delivery by peptide-DNA nano-coassemblies

Minimalist Design of an Intrinsically Disordered Protein-Mimicking Scaffold for an Artificial Membraneless Organelle

Molecular logic operations from complex coacervation with aggregation-induced emission characteristics

mRNA Delivery and Storage by Co-Assembling Nanostructures with Designer Oligopeptides

Multifaceted Cargo Recruitment and Release from Artificial Membraneless Organelles

Nucleic Acids Modulate Liquidity and Dynamics of Artificial Membraneless Organelles

Recent Advances in Surface Modification of Micro- and Nano-Scale Biomaterials with Biological Membranes and Biomolecules

Stochastic Lattice-Based Modeling of Macromolecule Release from Degradable Hydrogel

A bioinspired synthetic soft hydrogel for the treatment of dry eye

Altered Peptide Self-Assembly and Co-Assembly with DNA by Modification of Aromatic Residues

Controllable multi-phase protein release from in-situ hydrolyzable hydrogel

Droplet-Based Microfluidic Synthesis of Hydrogel Microparticles via Click Chemistry-Based Cross-Linking for the Controlled Release of Proteins

Enhanced Delivery of siRNA to Retinal Ganglion Cells by Intravitreal Lipid Nanoparticles of Positive Charge

The Effect Of Polysaccharide-Based Hydrogels On The Response Of Antigen-Presenting Cell Lines To Immunomodulators

Artificial membraneless organelle-based therapeutic system for regulation of RNAzyme directed gene therapy

Associate polymer theory-inspired modelling of intrinsically disordered protein-mimicking polymer-oligopeptide hybrids for the formation of artificial membraneless organelles

Characterization of Ultrasound-mediated Trans-corneal Delivery of Riboflavin by Modified Fluorotron™ Master

Low frequency ultrasound-mediated transcorneal delivery of riboflavin for corneal collagen crosslinking in treating keratoconus

Modulating artificial membraneless organelle via phosphorylation of oligopeptide

Nucleic acids modulate stiffness of artificial membraneless organelles

Recruitment and release of multifaceted cargoes from artificial membraneless organelles

The efficiency of low frequency ultrasound mediated delivery of riboflavin and biocompatibility of in-vivo rabbit cornea

Dual-Diffusivity Stochastic Model for Macromolecule Release from a Hydrogel

Local Environment-dependent Kinetics of Ester Hydrolysis Revealed by Direct ¹H NMR Measurement of Degrading Hydrogels

Nanoassembly of Oligopeptides and DNA Mimics the Sequential Disassembly of a Spherical Virus

The Synergy of Chemical Immobilization and Electrical Orientation of T4 Bacteriophage on a Micro Electrochemical Sensor for Low-Level Viable Bacteria Detection via Differential Pulse Voltammetry

3D physiological ocular pharmacokinetics model of anti-VEGF antibody after intravitreal injection with and without long-term depot

Controlled degradation and protein release from an injectable hydrogel in the posterior eye

Multi-month protein release from injectable, hydrolysable and biocompatible hydrogel in posterior rabbit eye

Responsive artificial membraneless organelles synthesis by dynamic assembly of polymer-oligopeptide hybrids and nucleic acids

Stochastic lattice-based model for macromolecules release from degradable hydrogel

A Self-assembled Peptidic Nanomillipede to Fabricate a Tuneable Hybrid Hydrogel

Co-encapsulation and co-delivery of peptide drugs via polymeric nanoparticles

Intracameral Injection of a Chemically Cross-linked Hydrogel to Study Chronic Neurodegeneration in Glaucoma

Intravitreal Nanoparticles for Retinal Delivery

Investigating impacts of surface charge on intraocular distribution of intravitreal lipid nanoparticles

Long-term Therapeutic Effect in Nonhuman Primate Eye From A Single Injection of Anti-VEGF Controlled Release Hydrogel

Phage-based electrochemical sensors: A review

Synthetic Approaches for Nucleic Acid Delivery: Choosing the Right Carriers

Enzyme-sensitive biomaterials for drug delivery

Mathematical models of drug release from degradable hydrogels

Nanoparticles for drug delivery targeting neurodegeneration in brain and eye

Injectable, hydrolytically degradable hydrogel for controllable, sustained protein release in the posterior eye

Low Intensity Low Frequency Ultrasound-mediated Transepithelial Delivery of Riboflavin in Porcine Cornea ex vivo

Self-assembling peptide/polymer hybrid as artificial proteoglycan for synthetic mechanically tunable extracellular matrix

Stochastic Lattice Based Distribution Model to Study Macromolecule Release from Hydrogels

Controlled release technology for anti-angiogenesis treatment of posterior eye diseases: Current status and challenges

Polymeric nanoparticles decorated with BDNF-derived peptide for neuron-targeted delivery of PTEN inhibitor

Stochastic Modeling of Degradation Behavior of Hydrogels

Ultrasound-facilitated assembly and disassembly of a pH-sensitive self-assembly peptide

Charged Lipid Nanoparticles for Targeted Retinal Delivery of Nucleic Acid Therapeutics

Effect of the surface charge of intravitreal lipid nanoparticles (LNPs) on their intraocular distribution

Effects of twice per day KN-A01, a modified hyaluronic acid based hydrogel, for the treatment of dry eye syndrome in dog patients

Empowering University Students on Social Innovation to Solve Global Health Issues

Histidine-facilitated efficient gene delivery of peptide-based viral mimics

Injectable Self-assembling Dextran-Peptide Hybrid Hydrogel with Self-healing and Shear-thinning Properties

Intracellular uptake mechanism of multi-ligand polymeric nanoparticles

Investigation of the Impacts of pegylation on The intraocular distribution of The intravitreal nanocarriers

Nature-inspired peptide-based virus mimics for plasmid DNA delivery

Stochastic distribution model for modelling macromolecules release from hydrogel

Stochastic Modeling of Macromolecule Release From Degradable Hydrogel

Synergy of Chemical Immobilization and AC Electrical Orientation of T4 Phage on a Micro Electrochemical Sensor for Bacteria Detection via Differential Pulse Voltammetry

Tunable protein release from injectable, degradable hydrogel depot over multiple months

Polymeric Vesicle Formation via Temperature-Assisted Nanoprecipitation

Tuning the Inter-nanofibril Interaction To Regulate the Morphology and Function of Peptide/DNA Co-assembled Viral Mimics

Ultrasound-Enhanced Penetration Through Sclera Depends On Frequency Of Sonication And Size Of Macromolecules

A wild type T4 based impedimetric wide-dynamic-range micro electrochemical sensor for detection of viable bacteria

Controlling the Long-range Inter-nanofibril Interaction to Regulate the Stability and Function of Peptide/DNA Co-assembled Nanococoons

Development of a long-acting artificial tear for veterinary use

Elevated Intraocular Pressure and Citicoline Affect Functional Connectivity in the Visual Pathway

In Vivo Evaluation of Hyaluronic Acid Based in Situ Hydrogel for Prolonged Release of Avastin in Monkey

Injectable, Degradable Dextran Based Hydrogel for Long Term Intraocular Macromolecular Therapeutics Delivery

Investigating the Impact of the Surface Properties of Intravitreally Injected Carriers on Their Retinal Bio-Distribution in a Single Nanoplatform

Ligand-modified polymeric nanoparticles for targeting specific brain region

Modified neuron-targeted polymeric nanoparticles for drug delivery to dorsal root ganglion

Release of Avastin from Polysaccharides Based in Situ Hydrogel and its Therapeutic Effect on Recurrent Choroidal Neovascularization Model in Monkey Eyes

Stochastic Modeling of Macromolecular Therapeutics Delivery from Hydrolytically Degradable Hydrogel Depot

Different Oligoarginine Modifications Alter Endocytic Pathways and Subcellular Trafficking of Polymeric Nanoparticles

Examination of Effects of Low-Frequency Ultrasound on Scleral Permeability and Collagen Network

Non-invasive MRI assessments of tissue microstructures and macromolecules in the eye upon biomechanical or biochemical modulation

Virus-Inspired Nucleic Acid Delivery System: Linking Virus and Viral Mimicry

Computational Modeling of Therapeutic Protein Distribution in the Rabbit Eye

Experiential learning experience in global health projects through design thinking

Modelling and controlling degradation and protein release profile from degradable polymer-polymer hydrogel depot

Regulation of the Gene Transfection of Peptide/DNA Hybrid Artificial “virus” by Peptide Sequence Variation

Cellular uptake enhancement and internalization pathway determination for intracellular polymeric particles

Formulation of In Situ Chemically Cross-Linked Hydrogel Depots for Protein Release: From the Blob Model Perspective

In vitro evaluation of the inhibitory effect of canine serum, canine fresh frozen plasma, freeze-thaw-cycled plasma, and Solcoseryl (TM) on matrix metalloproteinases 2 and 9

Injectable Chemically Crosslinked Hydrogel for the Controlled Release of Bevacizumab in Vitreous: A 6-Month In Vivo Study

Cellular uptake enhancement and endocytic trafficking of oligoarginine-modified polymeric nanoparticles

Robust formation of biodegradable polymeric vesicles via temperature-assisted nanoprecipitation

Size-dependent internalisation of folate-decorated nanoparticles via the pathways of clathrin and caveolae-mediated endocytosis in ARPE-19 cells

Structural Mimics of Viruses Through Peptide/DNA Co-Assembly

Three-dimensional self-assembling peptide matrix enhances the formation of embryoid bodies and their neuronal differentiation

A Novel Glaucoma Model Induced by Intracameral Injection of Cross-Linking Hydrogel

Biomechanical effect of low-intensity and low-frequency ultrasound on cellular transport of retinal pigment epithelium cells

Cellular uptake enhancement and internalization pathways determination for intracellular polymeric particles

Development of injectable hydrogel based on catalyst-free click chemistry for controlled release of macromolecules – a formulation study for Avastin

Folate-decorated nanoparticles exhibit size-dependent internalization and prolonged anti-angiogenic activity in retinal pigment epithelium cells

In vivo enhancement of transscleral penetration of macromolecules by low-intensity and low-frequency ultrasound

In vivo evaluation of hyaluronic acid based in situ hydrogel for prolonged release of Avastin by intravitreal injection

Modulation of scleral structure by low intensity and low frequency ultrasound

Study on process control of morphologies of polymeric self-assembles using Cryo-TEM imaging

Controllable formation of aromatic nanoparticles in a three-dimensional hydrodynamic flow focusing microfluidic device

Specific uptake of folate-decorated triamcinolone-encapsulating nanoparticles by retinal pigment epithelium cells enhances and prolongs antiangiogenic activity

Ultrasound-Mediated Transscleral Delivery of Macromolecules to the Posterior Segment of Rabbit Eye In Vivo

Effect of Different Oligoarginine Modification On Cellular Uptake and Intracellular Mechanism of Polymeric Nanoparticles

Mechanism of Ultrasound-mediated Transscleral Delivery: Temporary Alteration of Scleral Structure Increases Permeability of Macromolecules

Size and Morphology Control of Polymeric Nanoparticles By Tuning Polymer Components and Process Parameters

Factorial analysis of adaptable properties of self-assembling peptide matrix on cellular proliferation and neuronal differentiation of pluripotent embryonic carcinoma

One-Step "Click" Method for Generating Vinyl Sulfone Groups on Hydroxyl-Containing Water-Soluble Polymers

Self-assembly mediated platform for rapid and facile preparation of peptide-functionalized nanoparticles with high stability

A polyelectrolyte complex between lytic peptide-polymer conjugate and PGA as an efficient metabolic stress-inducing polymeric agent

Aromatic-directed self-assembly of biofunctional nanoparticles

Biodegradable Hyaluronic Acid in situ Hydrogel for Tissue Augmentation

Engineering biomaterials for drug delivery to the posterior segment

Hyaluronic acid based in situ hydrogel for controlled release of Avastin

Injectable hyaluronic acid-based hydrogel and its biomedical applications

Keynote speech: Engineering Biomaterials for Drug Delivery

Preparation of hyaluronic acid based in situ hydrogel for protein delivery to the eye

Three-dimensional self-assembling peptide matrix for forming and neuronal priming of totipotent embryonic body

A Facile Synthesis of Branched Poly(ethylene glycol) and its Heterobifunctional Derivatives

Efficient and facile formation of two-component nanoparticles via aromatic moiety directed self-assembly

Synthesis of X(Y)-(EO)n-OCH3 type heterobifunctional and X(Y)-(EO)n-Z type heterotrifunctional poly(ethylene glycol)s

Enzyme-Sensitive Biomaterials for Drug Delivery

Design, Synthesis and Characterization of Protease Sensitive Polymeric Vesicles

Droplet-based microfluidics for synthesis of organic nanoparticles

Synthesis and Characterization of Protease Triggered Morphology Change of Polymer-Peptide Vesicles

Integrating academic and mentoring support for the development of first-year ChE students in Hong Kong

Neural differentiation directed by self-assembling peptide scaffolds presenting laminin-derived epitopes

Synthesis of heterobifunctional poly(ethylene glycol)s by an acetal protection method

Synthesis, characterization, and in vivo evaluation of poly(ethylene oxide-co-glycidol)-platinate conjugate

Synthesis, characterization, and thermodynamic study of a polyvalent lytic peptide-polymer conjugate as novel anticancer agent

Ultrasound-enhanced intrascleral delivery of protein

Construction of soft nanocages from biomimetic self-assembly of bicomponent molecules

Dosage dependency of induced neuronal differentiation manipulated by the self assembly peptide niche

Enzyme-activated drug delivery systems

Hyaluronic acid based in situ hydrogel for controlled delivery of protein to the posterior segment of the eye

Investigation of the effects of ultrasound on protein transport through the sclera

Systematic study of niche characteristics for stem cell proliferation and neural differentiation

Ultrasound-mediated intrascleral drug delivery: Investigation on the effect of microbubbles

Ultrasound-mediated transscleral delivery of macromolecules: a study of changing ultrasound frequency and correlation with scleral pore size

Biomimetic Self-assembly of Triskelion Peptide Analogues into Supramolecular Polyhedra

Self-assembled peptide nanorods as building blocks of fractal patterns

Synthesis of Linear Polyether Polyol Derivatives As New Materials for Bioconjugation

Anticancer polymer-linker-drug conjugates

Antitumor activity of membrane-lytic peptides templated on a polymeric scaffold

Construction of nanofibrous films from dipeptide-based hierarchical assembly

Designing Biofunctionalized Self-assembling Peptide Matrices to Engineer Extracellular Microenvironment

Engineering properties of self-assembling peptide matrices by incorporating peptide epitopes in building blocks

Hollow vesicles self-assembled by short peptide derivatives

Mechanism for the self-assembly of fractal structures from dipeptide derivatives

Morphological control of self-assembling nanostructures by reverse microemulsion

Neural differentiation directed by self-assembling peptide matrix

Optimization of protease-sensitivity of polymer vesicles

Peptide-modified block copolymer for the assembly of stimuli-responsive vesicles

Polyether polyol as a new macromolecular carrier in an anticancer polymer-drug conjugate

Polyether polyol derivatives as new bioconjugate carriers

Polyether polyol -platinate conjugate and its micelle as new antitumor nanomedicines

Polymer-lytic peptide conjugate activated by tumor-associated protease

Polyvalent presentation of membrane-lytic peptides enhances antitumor potency

Protease-sensitive polymer vesicles for drug delivery

Protease-sensitive polymeric nanostructure for triggered release

Protease-sensitive polymeric vesicles as drug delivery vehicles

Self-assembling peptide matrix for probing effects of embedded extracellular matrix mimicking signals on stem cell behavior

Strategies for delivering therapeutics to the posterior segment of the eye

Tumor-targeted membrane lysing mediated by tumor-associated protease

Ultrasound-enhanced intrascleral delivery of protein”

Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase

Controlling self-assembly within nanospace for peptide nanoparticle fabrication

Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides - A model for biofunctional scaffolds

Control of anti-tumor activity of membrane lytic peptides via MT1-MMP mediation

Directing behavior of neural progenitor cells by altering spatial display of peptide signals in self-assembling matrix

Fabrication of peptide nanoparticles via temporal and spatial control of self-assembling

Formation of fractal structures from self-assembling dipeptide derivatives

Modular approach for designing biomimetic matrix to direct cell behavior

Morphology and size-controlled self-assembling of enzyme-responsive peptides

Self-assembly of biomimetic peptide nanocages with enzymatic control

Tailoring of self-assembling peptide scaffolds with biofunctional epitopes

A designer peptide template for self-assembling biomimetic nanofibrous hydrogel

Matrix metalloproteinase-activated anticancer nanomedicines

Novel matrix-metalloproteinase-activated polymer-peptide conjugates for targeted anticancer treatment

Peptide Nanogels for Ocular Drug Delivery

Self-assembling peptide nanoparticles for drug delivery

Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase overexpressing tumor xenograft model

A new paradigm in biomedical applications based on protease activation

A new paradigm in biomedical applications based on protease activation

Antitumor efficacy of a novel polymer peptide drug conjugate in human tumor xenograft models

Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix-metalloproteinase II and matrixmetalloproteinase IX

In vitro and in vivo investigation of new tumortargeting conjugates with MMP sensitive linkers

Case study: capacity challenges in chromatography-based purification of plasmid DNA

A novel polymer-peptide-drug conjugate for tumor targeting via MMP mediation

Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures

Important factors in designing targeted delivery of cancer therapeutics via MMP-2 mediation

Characterization of trypsin solutions for use in cell culture process development

Adsorption Behavior of Plasmid DNA on Chromatographic Resins

Controlled release technology for anti-angiogenesis treatment of posterior eye diseases: Current status and challenges

Article

Polymeric nanoparticles decorated with BDNF-derived peptide for neuron-targeted delivery of PTEN inhibitor

Article

Stochastic Modeling of Degradation Behavior of Hydrogels

Article

Ultrasound-facilitated assembly and disassembly of a pH-sensitive self-assembly peptide

Article

Charged Lipid Nanoparticles for Targeted Retinal Delivery of Nucleic Acid Therapeutics

Conference paper

Effect of the surface charge of intravitreal lipid nanoparticles (LNPs) on their intraocular distribution

Conference paper

Effects of twice per day KN-A01, a modified hyaluronic acid based hydrogel, for the treatment of dry eye syndrome in dog patients

Conference paper

Empowering University Students on Social Innovation to Solve Global Health Issues

Conference paper

Histidine-facilitated efficient gene delivery of peptide-based viral mimics

Conference paper

Injectable Self-assembling Dextran-Peptide Hybrid Hydrogel with Self-healing and Shear-thinning Properties

Conference paper

Intracellular uptake mechanism of multi-ligand polymeric nanoparticles

Conference paper

Investigation of the Impacts of pegylation on The intraocular distribution of The intravitreal nanocarriers

Conference paper

Nature-inspired peptide-based virus mimics for plasmid DNA delivery

Conference paper

Stochastic distribution model for modelling macromolecules release from hydrogel

Conference paper

Stochastic Modeling of Macromolecule Release From Degradable Hydrogel

Conference paper

Synergy of Chemical Immobilization and AC Electrical Orientation of T4 Phage on a Micro Electrochemical Sensor for Bacteria Detection via Differential Pulse Voltammetry

Conference paper

Tunable protein release from injectable, degradable hydrogel depot over multiple months

Conference paper

Polymeric Vesicle Formation via Temperature-Assisted Nanoprecipitation

Article

Tuning the Inter-nanofibril Interaction To Regulate the Morphology and Function of Peptide/DNA Co-assembled Viral Mimics

Article

Ultrasound-Enhanced Penetration Through Sclera Depends On Frequency Of Sonication And Size Of Macromolecules

Article

A wild type T4 based impedimetric wide-dynamic-range micro electrochemical sensor for detection of viable bacteria

Conference paper

Controlling the Long-range Inter-nanofibril Interaction to Regulate the Stability and Function of Peptide/DNA Co-assembled Nanococoons

Conference paper

Development of a long-acting artificial tear for veterinary use

Conference paper

Elevated Intraocular Pressure and Citicoline Affect Functional Connectivity in the Visual Pathway

Conference paper

In Vivo Evaluation of Hyaluronic Acid Based in Situ Hydrogel for Prolonged Release of Avastin in Monkey

Conference paper

Injectable, Degradable Dextran Based Hydrogel for Long Term Intraocular Macromolecular Therapeutics Delivery

Conference paper

Investigating the Impact of the Surface Properties of Intravitreally Injected Carriers on Their Retinal Bio-Distribution in a Single Nanoplatform

Conference paper

Ligand-modified polymeric nanoparticles for targeting specific brain region

Conference paper

Modified neuron-targeted polymeric nanoparticles for drug delivery to dorsal root ganglion

Conference paper

Release of Avastin from Polysaccharides Based in Situ Hydrogel and its Therapeutic Effect on Recurrent Choroidal Neovascularization Model in Monkey Eyes

Conference paper

Stochastic Modeling of Macromolecular Therapeutics Delivery from Hydrolytically Degradable Hydrogel Depot

Conference paper

Different Oligoarginine Modifications Alter Endocytic Pathways and Subcellular Trafficking of Polymeric Nanoparticles

Article

Examination of Effects of Low-Frequency Ultrasound on Scleral Permeability and Collagen Network

Article

Non-invasive MRI assessments of tissue microstructures and macromolecules in the eye upon biomechanical or biochemical modulation

Article

Virus-Inspired Nucleic Acid Delivery System: Linking Virus and Viral Mimicry

Article

Computational Modeling of Therapeutic Protein Distribution in the Rabbit Eye

Conference paper

Experiential learning experience in global health projects through design thinking

Conference paper

Modelling and controlling degradation and protein release profile from degradable polymer-polymer hydrogel depot

Conference paper

Regulation of the Gene Transfection of Peptide/DNA Hybrid Artificial “virus” by Peptide Sequence Variation

Conference paper

Cellular uptake enhancement and internalization pathway determination for intracellular polymeric particles

Article

Formulation of In Situ Chemically Cross-Linked Hydrogel Depots for Protein Release: From the Blob Model Perspective

Article

In vitro evaluation of the inhibitory effect of canine serum, canine fresh frozen plasma, freeze-thaw-cycled plasma, and Solcoseryl (TM) on matrix metalloproteinases 2 and 9

Article

Injectable Chemically Crosslinked Hydrogel for the Controlled Release of Bevacizumab in Vitreous: A 6-Month In Vivo Study

Article

Cellular uptake enhancement and endocytic trafficking of oligoarginine-modified polymeric nanoparticles

Conference paper

Robust formation of biodegradable polymeric vesicles via temperature-assisted nanoprecipitation

Conference paper

Size-dependent internalisation of folate-decorated nanoparticles via the pathways of clathrin and caveolae-mediated endocytosis in ARPE-19 cells

Article

Structural Mimics of Viruses Through Peptide/DNA Co-Assembly

Article

Three-dimensional self-assembling peptide matrix enhances the formation of embryoid bodies and their neuronal differentiation

Article

A Novel Glaucoma Model Induced by Intracameral Injection of Cross-Linking Hydrogel

Conference paper

Biomechanical effect of low-intensity and low-frequency ultrasound on cellular transport of retinal pigment epithelium cells

Conference paper

Cellular uptake enhancement and internalization pathways determination for intracellular polymeric particles

Conference paper

Development of injectable hydrogel based on catalyst-free click chemistry for controlled release of macromolecules – a formulation study for Avastin

Conference paper

Folate-decorated nanoparticles exhibit size-dependent internalization and prolonged anti-angiogenic activity in retinal pigment epithelium cells

Conference paper

In vivo enhancement of transscleral penetration of macromolecules by low-intensity and low-frequency ultrasound

Conference paper

In vivo evaluation of hyaluronic acid based in situ hydrogel for prolonged release of Avastin by intravitreal injection

Conference paper

Modulation of scleral structure by low intensity and low frequency ultrasound

Conference paper

Study on process control of morphologies of polymeric self-assembles using Cryo-TEM imaging

Conference paper

Controllable formation of aromatic nanoparticles in a three-dimensional hydrodynamic flow focusing microfluidic device

Article

Specific uptake of folate-decorated triamcinolone-encapsulating nanoparticles by retinal pigment epithelium cells enhances and prolongs antiangiogenic activity

Article

Ultrasound-Mediated Transscleral Delivery of Macromolecules to the Posterior Segment of Rabbit Eye In Vivo

Article

Effect of Different Oligoarginine Modification On Cellular Uptake and Intracellular Mechanism of Polymeric Nanoparticles

Conference paper

Mechanism of Ultrasound-mediated Transscleral Delivery: Temporary Alteration of Scleral Structure Increases Permeability of Macromolecules

Conference paper

Size and Morphology Control of Polymeric Nanoparticles By Tuning Polymer Components and Process Parameters

Conference paper

Factorial analysis of adaptable properties of self-assembling peptide matrix on cellular proliferation and neuronal differentiation of pluripotent embryonic carcinoma

Article

One-Step "Click" Method for Generating Vinyl Sulfone Groups on Hydroxyl-Containing Water-Soluble Polymers

Article

Self-assembly mediated platform for rapid and facile preparation of peptide-functionalized nanoparticles with high stability

Article

A polyelectrolyte complex between lytic peptide-polymer conjugate and PGA as an efficient metabolic stress-inducing polymeric agent

Conference paper

Aromatic-directed self-assembly of biofunctional nanoparticles

Conference paper

Biodegradable Hyaluronic Acid in situ Hydrogel for Tissue Augmentation

Conference paper

Engineering biomaterials for drug delivery to the posterior segment

Conference paper

Hyaluronic acid based in situ hydrogel for controlled release of Avastin

Conference paper

Injectable hyaluronic acid-based hydrogel and its biomedical applications

Conference paper

Keynote speech: Engineering Biomaterials for Drug Delivery

Conference paper

Preparation of hyaluronic acid based in situ hydrogel for protein delivery to the eye

Conference paper

Three-dimensional self-assembling peptide matrix for forming and neuronal priming of totipotent embryonic body

Conference paper

A Facile Synthesis of Branched Poly(ethylene glycol) and its Heterobifunctional Derivatives

Article

Efficient and facile formation of two-component nanoparticles via aromatic moiety directed self-assembly

Article

Synthesis of X(Y)-(EO)n-OCH3 type heterobifunctional and X(Y)-(EO)n-Z type heterotrifunctional poly(ethylene glycol)s

Article

Enzyme-Sensitive Biomaterials for Drug Delivery

Book chapter

Design, Synthesis and Characterization of Protease Sensitive Polymeric Vesicles

Conference paper

Droplet-based microfluidics for synthesis of organic nanoparticles

Conference paper

Synthesis and Characterization of Protease Triggered Morphology Change of Polymer-Peptide Vesicles

Conference paper

Integrating academic and mentoring support for the development of first-year ChE students in Hong Kong

Article

Neural differentiation directed by self-assembling peptide scaffolds presenting laminin-derived epitopes

Article

Synthesis of heterobifunctional poly(ethylene glycol)s by an acetal protection method

Article

Synthesis, characterization, and in vivo evaluation of poly(ethylene oxide-co-glycidol)-platinate conjugate

Article

Synthesis, characterization, and thermodynamic study of a polyvalent lytic peptide-polymer conjugate as novel anticancer agent

Article

Ultrasound-enhanced intrascleral delivery of protein

Article

Construction of soft nanocages from biomimetic self-assembly of bicomponent molecules

Conference paper

Dosage dependency of induced neuronal differentiation manipulated by the self assembly peptide niche

Conference paper

Enzyme-activated drug delivery systems

Conference paper

Hyaluronic acid based in situ hydrogel for controlled delivery of protein to the posterior segment of the eye

Conference paper

Investigation of the effects of ultrasound on protein transport through the sclera

Conference paper

Systematic study of niche characteristics for stem cell proliferation and neural differentiation

Conference paper

Ultrasound-mediated intrascleral drug delivery: Investigation on the effect of microbubbles

Conference paper

Ultrasound-mediated transscleral delivery of macromolecules: a study of changing ultrasound frequency and correlation with scleral pore size

Conference paper

Biomimetic Self-assembly of Triskelion Peptide Analogues into Supramolecular Polyhedra

Article

Self-assembled peptide nanorods as building blocks of fractal patterns

Article

Synthesis of Linear Polyether Polyol Derivatives As New Materials for Bioconjugation

Article

Anticancer polymer-linker-drug conjugates

Conference paper

Antitumor activity of membrane-lytic peptides templated on a polymeric scaffold

Conference paper

Construction of nanofibrous films from dipeptide-based hierarchical assembly

Conference paper

Designing Biofunctionalized Self-assembling Peptide Matrices to Engineer Extracellular Microenvironment

Conference paper

Engineering properties of self-assembling peptide matrices by incorporating peptide epitopes in building blocks

Conference paper

Hollow vesicles self-assembled by short peptide derivatives

Conference paper

Mechanism for the self-assembly of fractal structures from dipeptide derivatives

Conference paper

Morphological control of self-assembling nanostructures by reverse microemulsion

Conference paper

Neural differentiation directed by self-assembling peptide matrix

Conference paper

Optimization of protease-sensitivity of polymer vesicles

Conference paper

Peptide-modified block copolymer for the assembly of stimuli-responsive vesicles

Conference paper

Polyether polyol as a new macromolecular carrier in an anticancer polymer-drug conjugate

Conference paper

Polyether polyol derivatives as new bioconjugate carriers

Conference paper

Polyether polyol -platinate conjugate and its micelle as new antitumor nanomedicines

Conference paper

Polymer-lytic peptide conjugate activated by tumor-associated protease

Conference paper

Polyvalent presentation of membrane-lytic peptides enhances antitumor potency

Conference paper

Protease-sensitive polymer vesicles for drug delivery

Conference paper

Protease-sensitive polymeric nanostructure for triggered release

Conference paper

Protease-sensitive polymeric vesicles as drug delivery vehicles

Conference paper

Self-assembling peptide matrix for probing effects of embedded extracellular matrix mimicking signals on stem cell behavior

Conference paper

Strategies for delivering therapeutics to the posterior segment of the eye

Conference paper

Tumor-targeted membrane lysing mediated by tumor-associated protease

Conference paper

Ultrasound-enhanced intrascleral delivery of protein”

Conference paper

Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase

Article

Controlling self-assembly within nanospace for peptide nanoparticle fabrication

Article

Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides - A model for biofunctional scaffolds

Article

Control of anti-tumor activity of membrane lytic peptides via MT1-MMP mediation

Conference paper

Directing behavior of neural progenitor cells by altering spatial display of peptide signals in self-assembling matrix

Conference paper

Fabrication of peptide nanoparticles via temporal and spatial control of self-assembling

Conference paper

Formation of fractal structures from self-assembling dipeptide derivatives

Conference paper

Modular approach for designing biomimetic matrix to direct cell behavior

Conference paper

Morphology and size-controlled self-assembling of enzyme-responsive peptides

Conference paper

Self-assembly of biomimetic peptide nanocages with enzymatic control

Conference paper

Tailoring of self-assembling peptide scaffolds with biofunctional epitopes

Conference paper

A designer peptide template for self-assembling biomimetic nanofibrous hydrogel

Conference paper

Matrix metalloproteinase-activated anticancer nanomedicines

Conference paper

Novel matrix-metalloproteinase-activated polymer-peptide conjugates for targeted anticancer treatment

Conference paper

Peptide Nanogels for Ocular Drug Delivery

Conference paper

Self-assembling peptide nanoparticles for drug delivery

Conference paper

Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase overexpressing tumor xenograft model

Article

A new paradigm in biomedical applications based on protease activation

Conference paper

A new paradigm in biomedical applications based on protease activation

Conference paper

Antitumor efficacy of a novel polymer peptide drug conjugate in human tumor xenograft models

Article

Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix-metalloproteinase II and matrixmetalloproteinase IX

Article

In vitro and in vivo investigation of new tumortargeting conjugates with MMP sensitive linkers

Conference paper

Case study: capacity challenges in chromatography-based purification of plasmid DNA

Article

A novel polymer-peptide-drug conjugate for tumor targeting via MMP mediation

Conference paper

Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures

Article

Important factors in designing targeted delivery of cancer therapeutics via MMP-2 mediation

Conference paper

Characterization of trypsin solutions for use in cell culture process development

Conference paper

Adsorption Behavior of Plasmid DNA on Chromatographic Resins

Conference paper