FZD5 controls intestinal crypt homeostasis and colonic Wnt surrogate agonist response

TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting Wnt and BMP signaling

Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination

Activation of Wnt/β-catenin signaling by Zeb1 in endothelial progenitors induces vascular quiescence entry

Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co-Condensation of Wnt Signalodroplets

Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development

Mutational signature in colorectal cancer caused by genotoxic pks + E. coli

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo

Structure of human frizzled5 by fiducial-assisted cryo-em supports a heterodimeric mechanism of canonical wnt signaling

Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling

Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

Receptor subtype discrimination using extensive shape complementary designed interfaces

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability

Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design

Trehalose pathway as an antifungal target

Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis

Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

Article

Receptor subtype discrimination using extensive shape complementary designed interfaces

Article

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

Article

A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability

Article

Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design

Article

Trehalose pathway as an antifungal target

Article

Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis

Article

Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China

Article