Faculty Profiles - DUAN Yangyang | The Hong Kong University of Science and Technology

Yangyang DUAN
段揚揚

PhD in Life Science
The Hong Kong University of Science and Technology, 2022

Research Assistant Professor
Division of Life Science

(852) 2358 8781
yyduan@ust.hk
Room 6313

Google Scholar

IMacTF4AAAAJ

ORCID

0000-0002-0823-6574

Scopus ID

56555745300

Research Interest Publications Projects

Research Interest

Neurobiology and neurosciences
Neurodegenerative and age-related disorders
Gene therapy
Molecular mechanisms of neurodegeneration

Publications

All Years 4 2024 0 2023 0 2022 2 2021 1 2020 0 2019 0 2018 1

2022 2

AAV Capsid Variants with Brain-Wide Transgene Expression and Decreased Liver Targeting after Intravenous Delivery in Mouse and marmoset

Nature Neuroscience, v. 25, (1), January 2022, p. 106-115
Goertsen, David; Flytzanis, Nicholas C.; Goeden, Nick; Chuapoco, Miguel; Cummins, Alexander; Chen, Yijing; Fan, Yingying; Zhang, Qiangge; Sharma, Jitendra; Duan, Yangyang; Wang, Liping; Feng, Guoping; Chen, Yu; Ip, Nancy Yuk-Yu; Pickel, James; Gradinaru, Viviana
Article

Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Nature Biomedical Engineering, v. 6, (2), February 2022, p. 168-180
Duan, Yangyang; Ye, Tao; Qu, Zhe; Chen, Yuewen; Miranda, Abigail Orquiza; Zhou, Xiaopu; Lok, Ka Chun; Chen, Yu; Fu, Kit Yu; Gradinaru, Viviana; Ip, Nancy Yuk-yu
Article

2021 1

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Communications Biology, v. 4, (1), February 2021, article number 195
Ye, Tao; Duan, Yangyang; Tsang, Hayley Wing Sum; Xu, He; Chen, Yuewen; Cao, Han; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

2015 1

β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network

Journal of Biological Chemistry, v. 290, (10), March 2015, p. 6397-6407
Wong, Kin Lam Kenneth; Li, Wenyang; An, Yanru; Duan, Yangyang; Li, Zhuoheng; Kang, Yibin; Yan, Yan
Article

Article 2

AAV Capsid Variants with Brain-Wide Transgene Expression and Decreased Liver Targeting after Intravenous Delivery in Mouse and marmoset

Nature Neuroscience, v. 25, (1), January 2022, p. 106-115
Goertsen, David; Flytzanis, Nicholas C.; Goeden, Nick; Chuapoco, Miguel; Cummins, Alexander; Chen, Yijing; Fan, Yingying; Zhang, Qiangge; Sharma, Jitendra; Duan, Yangyang; Wang, Liping; Feng, Guoping; Chen, Yu; Ip, Nancy Yuk-Yu; Pickel, James; Gradinaru, Viviana

Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Nature Biomedical Engineering, v. 6, (2), February 2022, p. 168-180
Duan, Yangyang; Ye, Tao; Qu, Zhe; Chen, Yuewen; Miranda, Abigail Orquiza; Zhou, Xiaopu; Lok, Ka Chun; Chen, Yu; Fu, Kit Yu; Gradinaru, Viviana; Ip, Nancy Yuk-yu

Article 1

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Communications Biology, v. 4, (1), February 2021, article number 195
Ye, Tao; Duan, Yangyang; Tsang, Hayley Wing Sum; Xu, He; Chen, Yuewen; Cao, Han; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Article 1

β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network

Journal of Biological Chemistry, v. 290, (10), March 2015, p. 6397-6407
Wong, Kin Lam Kenneth; Li, Wenyang; An, Yanru; Duan, Yangyang; Li, Zhuoheng; Kang, Yibin; Yan, Yan

2015 1

β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network

Journal of Biological Chemistry, v. 290, (10), March 2015, p. 6397-6407
Wong, Kin Lam Kenneth; Li, Wenyang; An, Yanru; Duan, Yangyang; Li, Zhuoheng; Kang, Yibin; Yan, Yan
Article

No Publications

Projects

From January 2022 to December 2024

All Projects 1

No Projects.
Investigating the effects and underlying mechanisms of Aβ reduction on Alzheimer’s pathologies in a transgenic mouse model

轉基因小鼠模型中 β-澱粉樣蛋白下調對阿茲海默癥病理的影響及調控機制 Leading

RGC - General Research Fund
Project Team (HKUST)
DUAN Yangyang (Lead)

FU Amy Kit Yu

IP Nancy Yuk-Yu
2024 -

Research Interest

Publications

2022 2

2021 1

2015 1

Article 2

Article 1

Article 1

2015 1

Projects

From January 2022 to December 2024

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