Faculty Profiles - YAN Yan | The Hong Kong University of Science and Technology

Yan YAN
閻言

PhD in Molecular Biology
Princeton University, 2010

Associate Professor
Division of Life Science

(852) 2358 5929
yany@ust.hk
Room 5511
Personal Web

Google Scholar

-1n_vjgAAAAJ

ORCID

0000-0002-3677-5006

Scopus ID

35112171400

Research Interest Publications Projects Teaching Assignment RPG Supervision Space used

Research Interest

Drosophila tumor model

Publications

All Years 28 2025 0 2024 4 2023 1 2022 1 2021 0 2020 2 2019 20

2024 4

Ehbp1 orchestrates orderly sorting of Wnt/Wingless to the basolateral and apical cell membranes

EMBO Reports, v. 25, (11), November 2024, p. 5053-5079
Gao, Yuan; Feng, Jing; Zhang, Yansong; Yi, Mengyuan; Zhang, Lebing; Yan, Yan; Zhu, Alan Jian; Liu, Min
Article

Testis-specific H2B.W1 disrupts nucleosome integrity by reducing DNA-histone interactions

Nucleic Acids Research, v. 52, (19), October 2024, p. 11612-11625
Ding, Dongbo; Pang, Yu Hin; Deng, Mingxi; Nguyen, Thi Thuy; Liu, Yue; Sun, Xulun; Xu, Zhichun; Zhang, Yingyi; Zhai, Yuanliang; Yan, Yan; Ishibashi, Toyotaka
Article

Visualizing Low-Abundance Proteins and Post-Translational Modifications in Living Drosophila Embryos via Fluorescent Antibody Injection

Journal of Visualized Experiments (JoVE), v. 2024, (203), January 2024, article number e66080
Zheng, Qihong; Xiang, Xiaoxiang; Yan, Yan; Yu, Huapeng H.
Article

Formation of destabilized nucleosome core particles by spermatogenesis-specific histone variant H2BFWT and its infertility-associated mutant H2BFWT-H100R: Insights from single-molecule optical tweezers and cryo-electron microscopy

Biophysical Journal, v. 123, (3, Supplement 1), February 2024, article number 230A
Pang, Yu Hin; Ding, Dongbo; Deng, Mingxi; Nguyen, Thi Thuy; Sun, Xulun; Liu, Yue; Yan, Yan; Ishibashi, Toyotaka
Conference paper

2023 1

Construction of a 3D whole organism spatial atlas by joint modelling of multiple slices with deep neural networks

Nature Machine Intelligence, v. 5, (11), November 2023, p. 1200-1213
Wang, Gefei; Zhao, Jia; Yan, Yan; Wang, Yang; Wu, Angela Ruohao; Yang, Can
Article

2022 1

Mining cell-cell signaling in single-cell transcriptomics atlases

Current Opinion in Cell Biology, v. 76, June 2022, article number 102101
Deng, Mingxi; Wang, Ying; Yan, Yan
Article

2020 2

Dynamically Tunable, Macroscopic Molecular Networks Enabled by Cellular Synthesis of 4-Arm Star-like Proteins

Matter, v. 2, (1), January 2020, p. 233-249
Yang, Zhongguang; Yang, Yang; Wang, Mo; Wang, Tingting; Fok, Hong Kiu Francis; Jiang, Bojing; Xiao, Wendi; Kou, Songzi; Guo, Yusong; Yan, Yan; Deng, Xin; Zhang, Wen-Bin; Sun, Fei
Article

Molecular Mechanisms That Regulate Export of the Planar Cell-Polarity Protein Frizzled-6 Out of the Endoplasmic Reticulum

Journal of Biological Chemistry, v. 295, (27), July 2020, p. 8972-8987
Tang, Xiao; Zhang, Lina; Ma, Tianji; Wang, Mo; Li, Baiying; Jiang, Liwen; Yan, Yan; Guo, Yusong
Article

2019 3

A Novel Histone H4 Variant H4G Regulates rDNA Transcription in Breast Cancer

Nucleic Acids Research, v. 47, (16), September 2019, p. 8399-8409
Long, Mengping; Sun, Xulun; Shi, Wenjin; An, Yanru; Leung, Tsz Chui Sophia; Ding, Dongbo; Cheema, Manjinder S.; MacPherson, Nicol; Nelson, Christopher J.; Ausio, Juan; Yan, Yan; Ishibashi, Toyotaka
Article

Dynamic MAPK Signaling Activity Underlies a Transition From Growth Arrest to Proliferation in Drosophila Scribble Mutant Tumors

DMM Disease Models and Mechanism, v. 12, (8), August 2019, article number dmm040147
Ji, Tiantian; Zhang, Lina; Deng, Mingxi; Huang, Shengshuo; Wang, Ying; Pham, Tri Thanh; Smith, Andrew Alan; Sridhar, Varun; Cabernard, Clemens; Wang, Jiguang; Yan, Yan
Article

Single cell transcriptomic landscapes of pattern formation, proliferation and growth in Drosophila wing imaginal discs

Development, v. 146, (18), September 2019, article number dev179754, p. 1-10
Deng, Mingxi; Wang, Ying; Zhang, Lina; Yang, Yang; Huang, Shengshuo; Wang, Jiguang; Ge, H.; Ishibashi, Toyotaka; Yan, Yan
Article

2018 2

Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila

Current Biology, v. 28, (11), June 2018, p. 1756-1767
Katsukawa, Mitsuko; Ohsawa, Shizue; Zhang, Lina; Yan, Yan; Igaki, Tatsushi
Article

Molecular and cellular basis of Drosophila neuroblast delamination

An, Yanru; Yang, Shaobo; Yan, Yan
Conference paper

2017 5

Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts

Development, v. 144, (12), June 2017, p. 2153-2164
An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan
Article

Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts

An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan
Conference paper

Apical Constriction is Driven by a Pulsatile Apical Myosin Network in Delaminating Drosophila Neuroblasts

An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan
Conference paper

Dscam4 is required for elimination of polarity-deficient cells in Drosophila

Yan, Yan; Zhang, Lina; Wang,ying; Yang, Yang
Conference paper

Molecular and cellular basis of Drosophila neuroblast delamination

Mechanisms of Development, v. 145, (Suppl.), July 2017, article number PS5.48, p. S158
An, Yanru; Xue, Guosheng; Ishibashi, Toyotaka; Yan, Yan
Conference paper

2016 2

Quantitative analysis of myosin-driven apical constriction in delaminating neuroblasts

An, Yanru; Xue, Guosheng; Ishibashi, Toyotaka; Chris, Doe; Yan, Yan
Conference paper

2015 2

β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network

Journal of Biological Chemistry, v. 290, (10), March 2015, p. 6397-6407
Wong, Kin Lam Kenneth; Li, Wenyang; An, Yanru; Duan, Yangyang; Li, Zhuoheng; Kang, Yibin; Yan, Yan
Article

Quantitative Analysis of Single Cell Delamination in Drosophila

Yan, Yan
Conference paper

2014 2

Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

Proceedings of the National Academy of Sciences of the United States of America, v. 111, (49), December 2014, p. 17444-17449
Li, Youjun; Wei, Zhiyi; Yan, Yan; Wan, Qingwen; Du, Quansheng; Zhang, Mingjie
Article

The Molecular and Cellular Basis of Cell Delamination

An, Yanru; Yan, Yan
Conference paper

2011 2

Drosophila PI4KIIIalpha is Required in Follicle Cells for Oocyte Polarization and Hippo Signaling

Development, v. 138, (9), 2011, May, p. 1697-1703
Yan, Yan; Denef, Natalie; Tang, Charm; Schuepbach, Trudi
Article

Regulation of Somatic Myosin Activity by Protein Phosphatase 1 Beta Controls Drosophila Oocyte Polarization

Development, v. 138, (10), 2011, May, p. 1991-2001
Sun, Yi; Yan, Yan; Denef, Natalie; Schuepbach, Trudi
Article

2010 1

Rabconnectin-3 Is a Functional Regulator of Mammalian Notch Signaling

Journal of Biological Chemistry, v. 285, (45), 2010, Nov, p. 34757-34764
Sethi, Nilay; Yan, Yan; Quek, Debra; Schupbach, Trudi; Kang, Yibin
Article

2009 1

The Vacuolar Proton Pump, V-ATPase, Is Required for Notch Signaling and Endosomal Trafficking in Drosophila

Developmental Cell, v. 17, (3), 2009, Sep, p. 387-402
Yan, Yan; Denef, Natalie; Schupbach, Trudi
Article

Article 3

Ehbp1 orchestrates orderly sorting of Wnt/Wingless to the basolateral and apical cell membranes

EMBO Reports, v. 25, (11), November 2024, p. 5053-5079
Gao, Yuan; Feng, Jing; Zhang, Yansong; Yi, Mengyuan; Zhang, Lebing; Yan, Yan; Zhu, Alan Jian; Liu, Min

Testis-specific H2B.W1 disrupts nucleosome integrity by reducing DNA-histone interactions

Nucleic Acids Research, v. 52, (19), October 2024, p. 11612-11625
Ding, Dongbo; Pang, Yu Hin; Deng, Mingxi; Nguyen, Thi Thuy; Liu, Yue; Sun, Xulun; Xu, Zhichun; Zhang, Yingyi; Zhai, Yuanliang; Yan, Yan; Ishibashi, Toyotaka

Visualizing Low-Abundance Proteins and Post-Translational Modifications in Living Drosophila Embryos via Fluorescent Antibody Injection

Journal of Visualized Experiments (JoVE), v. 2024, (203), January 2024, article number e66080
Zheng, Qihong; Xiang, Xiaoxiang; Yan, Yan; Yu, Huapeng H.

Conference paper 1

Formation of destabilized nucleosome core particles by spermatogenesis-specific histone variant H2BFWT and its infertility-associated mutant H2BFWT-H100R: Insights from single-molecule optical tweezers and cryo-electron microscopy

Biophysical Journal, v. 123, (3, Supplement 1), February 2024, article number 230A
Pang, Yu Hin; Ding, Dongbo; Deng, Mingxi; Nguyen, Thi Thuy; Sun, Xulun; Liu, Yue; Yan, Yan; Ishibashi, Toyotaka

Article 1

Construction of a 3D whole organism spatial atlas by joint modelling of multiple slices with deep neural networks

Nature Machine Intelligence, v. 5, (11), November 2023, p. 1200-1213
Wang, Gefei; Zhao, Jia; Yan, Yan; Wang, Yang; Wu, Angela Ruohao; Yang, Can

Article 1

Mining cell-cell signaling in single-cell transcriptomics atlases

Current Opinion in Cell Biology, v. 76, June 2022, article number 102101
Deng, Mingxi; Wang, Ying; Yan, Yan

Article 2

Dynamically Tunable, Macroscopic Molecular Networks Enabled by Cellular Synthesis of 4-Arm Star-like Proteins

Matter, v. 2, (1), January 2020, p. 233-249
Yang, Zhongguang; Yang, Yang; Wang, Mo; Wang, Tingting; Fok, Hong Kiu Francis; Jiang, Bojing; Xiao, Wendi; Kou, Songzi; Guo, Yusong; Yan, Yan; Deng, Xin; Zhang, Wen-Bin; Sun, Fei

Molecular Mechanisms That Regulate Export of the Planar Cell-Polarity Protein Frizzled-6 Out of the Endoplasmic Reticulum

Journal of Biological Chemistry, v. 295, (27), July 2020, p. 8972-8987
Tang, Xiao; Zhang, Lina; Ma, Tianji; Wang, Mo; Li, Baiying; Jiang, Liwen; Yan, Yan; Guo, Yusong

Article 3

A Novel Histone H4 Variant H4G Regulates rDNA Transcription in Breast Cancer

Nucleic Acids Research, v. 47, (16), September 2019, p. 8399-8409
Long, Mengping; Sun, Xulun; Shi, Wenjin; An, Yanru; Leung, Tsz Chui Sophia; Ding, Dongbo; Cheema, Manjinder S.; MacPherson, Nicol; Nelson, Christopher J.; Ausio, Juan; Yan, Yan; Ishibashi, Toyotaka

Dynamic MAPK Signaling Activity Underlies a Transition From Growth Arrest to Proliferation in Drosophila Scribble Mutant Tumors

DMM Disease Models and Mechanism, v. 12, (8), August 2019, article number dmm040147
Ji, Tiantian; Zhang, Lina; Deng, Mingxi; Huang, Shengshuo; Wang, Ying; Pham, Tri Thanh; Smith, Andrew Alan; Sridhar, Varun; Cabernard, Clemens; Wang, Jiguang; Yan, Yan

Single cell transcriptomic landscapes of pattern formation, proliferation and growth in Drosophila wing imaginal discs

Development, v. 146, (18), September 2019, article number dev179754, p. 1-10
Deng, Mingxi; Wang, Ying; Zhang, Lina; Yang, Yang; Huang, Shengshuo; Wang, Jiguang; Ge, H.; Ishibashi, Toyotaka; Yan, Yan

Article 1

Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila

Current Biology, v. 28, (11), June 2018, p. 1756-1767
Katsukawa, Mitsuko; Ohsawa, Shizue; Zhang, Lina; Yan, Yan; Igaki, Tatsushi

Conference paper 1

Molecular and cellular basis of Drosophila neuroblast delamination

An, Yanru; Yang, Shaobo; Yan, Yan

Article 1

Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts

Development, v. 144, (12), June 2017, p. 2153-2164
An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan

Conference paper 4

Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts

An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan

Apical Constriction is Driven by a Pulsatile Apical Myosin Network in Delaminating Drosophila Neuroblasts

An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan

Dscam4 is required for elimination of polarity-deficient cells in Drosophila

Yan, Yan; Zhang, Lina; Wang,ying; Yang, Yang

Molecular and cellular basis of Drosophila neuroblast delamination

Mechanisms of Development, v. 145, (Suppl.), July 2017, article number PS5.48, p. S158
An, Yanru; Xue, Guosheng; Ishibashi, Toyotaka; Yan, Yan

Conference paper 2

Quantitative analysis of myosin-driven apical constriction in delaminating neuroblasts

An, Yanru; Xue, Guosheng; Ishibashi, Toyotaka; Chris, Doe; Yan, Yan

Article 1

β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network

Journal of Biological Chemistry, v. 290, (10), March 2015, p. 6397-6407
Wong, Kin Lam Kenneth; Li, Wenyang; An, Yanru; Duan, Yangyang; Li, Zhuoheng; Kang, Yibin; Yan, Yan

Conference paper 1

Quantitative Analysis of Single Cell Delamination in Drosophila

Yan, Yan

Article 1

Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

Proceedings of the National Academy of Sciences of the United States of America, v. 111, (49), December 2014, p. 17444-17449
Li, Youjun; Wei, Zhiyi; Yan, Yan; Wan, Qingwen; Du, Quansheng; Zhang, Mingjie

Conference paper 1

The Molecular and Cellular Basis of Cell Delamination

An, Yanru; Yan, Yan

Article 2

Drosophila PI4KIIIalpha is Required in Follicle Cells for Oocyte Polarization and Hippo Signaling

Development, v. 138, (9), 2011, May, p. 1697-1703
Yan, Yan; Denef, Natalie; Tang, Charm; Schuepbach, Trudi

Regulation of Somatic Myosin Activity by Protein Phosphatase 1 Beta Controls Drosophila Oocyte Polarization

Development, v. 138, (10), 2011, May, p. 1991-2001
Sun, Yi; Yan, Yan; Denef, Natalie; Schuepbach, Trudi

Article 1

Rabconnectin-3 Is a Functional Regulator of Mammalian Notch Signaling

Journal of Biological Chemistry, v. 285, (45), 2010, Nov, p. 34757-34764
Sethi, Nilay; Yan, Yan; Quek, Debra; Schupbach, Trudi; Kang, Yibin

Article 1

The Vacuolar Proton Pump, V-ATPase, Is Required for Notch Signaling and Endosomal Trafficking in Drosophila

Developmental Cell, v. 17, (3), 2009, Sep, p. 387-402
Yan, Yan; Denef, Natalie; Schupbach, Trudi

2019 3

A Novel Histone H4 Variant H4G Regulates rDNA Transcription in Breast Cancer

Nucleic Acids Research, v. 47, (16), September 2019, p. 8399-8409
Long, Mengping; Sun, Xulun; Shi, Wenjin; An, Yanru; Leung, Tsz Chui Sophia; Ding, Dongbo; Cheema, Manjinder S.; MacPherson, Nicol; Nelson, Christopher J.; Ausio, Juan; Yan, Yan; Ishibashi, Toyotaka
Article

Dynamic MAPK Signaling Activity Underlies a Transition From Growth Arrest to Proliferation in Drosophila Scribble Mutant Tumors

DMM Disease Models and Mechanism, v. 12, (8), August 2019, article number dmm040147
Ji, Tiantian; Zhang, Lina; Deng, Mingxi; Huang, Shengshuo; Wang, Ying; Pham, Tri Thanh; Smith, Andrew Alan; Sridhar, Varun; Cabernard, Clemens; Wang, Jiguang; Yan, Yan
Article

Single cell transcriptomic landscapes of pattern formation, proliferation and growth in Drosophila wing imaginal discs

Development, v. 146, (18), September 2019, article number dev179754, p. 1-10
Deng, Mingxi; Wang, Ying; Zhang, Lina; Yang, Yang; Huang, Shengshuo; Wang, Jiguang; Ge, H.; Ishibashi, Toyotaka; Yan, Yan
Article

2018 2

Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila

Current Biology, v. 28, (11), June 2018, p. 1756-1767
Katsukawa, Mitsuko; Ohsawa, Shizue; Zhang, Lina; Yan, Yan; Igaki, Tatsushi
Article

Molecular and cellular basis of Drosophila neuroblast delamination

An, Yanru; Yang, Shaobo; Yan, Yan
Conference paper

2017 5

Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts

Development, v. 144, (12), June 2017, p. 2153-2164
An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan
Article

Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts

An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan
Conference paper

Apical Constriction is Driven by a Pulsatile Apical Myosin Network in Delaminating Drosophila Neuroblasts

An, Yanru; Xue, Guosheng; Yang, Shaobo; Deng, Mingxi; Zhou, Xiaowei; Yu, Weichuan; Ishibashi, Toyotaka; Zhang, Lei; Yan, Yan
Conference paper

Dscam4 is required for elimination of polarity-deficient cells in Drosophila

Yan, Yan; Zhang, Lina; Wang,ying; Yang, Yang
Conference paper

Molecular and cellular basis of Drosophila neuroblast delamination

Mechanisms of Development, v. 145, (Suppl.), July 2017, article number PS5.48, p. S158
An, Yanru; Xue, Guosheng; Ishibashi, Toyotaka; Yan, Yan
Conference paper

2016 2

Quantitative analysis of myosin-driven apical constriction in delaminating neuroblasts

An, Yanru; Xue, Guosheng; Ishibashi, Toyotaka; Chris, Doe; Yan, Yan
Conference paper

2015 2

β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network

Journal of Biological Chemistry, v. 290, (10), March 2015, p. 6397-6407
Wong, Kin Lam Kenneth; Li, Wenyang; An, Yanru; Duan, Yangyang; Li, Zhuoheng; Kang, Yibin; Yan, Yan
Article

Quantitative Analysis of Single Cell Delamination in Drosophila

Yan, Yan
Conference paper

2014 2

Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

Proceedings of the National Academy of Sciences of the United States of America, v. 111, (49), December 2014, p. 17444-17449
Li, Youjun; Wei, Zhiyi; Yan, Yan; Wan, Qingwen; Du, Quansheng; Zhang, Mingjie
Article

The Molecular and Cellular Basis of Cell Delamination

An, Yanru; Yan, Yan
Conference paper

2011 2

Drosophila PI4KIIIalpha is Required in Follicle Cells for Oocyte Polarization and Hippo Signaling

Development, v. 138, (9), 2011, May, p. 1697-1703
Yan, Yan; Denef, Natalie; Tang, Charm; Schuepbach, Trudi
Article

Regulation of Somatic Myosin Activity by Protein Phosphatase 1 Beta Controls Drosophila Oocyte Polarization

Development, v. 138, (10), 2011, May, p. 1991-2001
Sun, Yi; Yan, Yan; Denef, Natalie; Schuepbach, Trudi
Article

2010 1

Rabconnectin-3 Is a Functional Regulator of Mammalian Notch Signaling

Journal of Biological Chemistry, v. 285, (45), 2010, Nov, p. 34757-34764
Sethi, Nilay; Yan, Yan; Quek, Debra; Schupbach, Trudi; Kang, Yibin
Article

2009 1

The Vacuolar Proton Pump, V-ATPase, Is Required for Notch Signaling and Endosomal Trafficking in Drosophila

Developmental Cell, v. 17, (3), 2009, Sep, p. 387-402
Yan, Yan; Denef, Natalie; Schupbach, Trudi
Article

No Publications

Teaching Assignment

2024-25 Spring 4 2024-25 Winter 0 2024-25 Fall 4 2023-24 Summer 0 2023-24 Spring 4 2023-24 Winter 0

LIFS5260	Biochemical and Molecular Basis of Diseases
LIFS6111V	Life Science Postgraduate Student Seminar
LIFS6115H	Current Topics in Development and Systems Biology
LIFS6410H	Seminar Enrichment Course

LIFS4090	Developmental Biology
LIFS4961	Biochemistry and Cell Biology Capstone Project
LIFS6170	Special Topics in Molecular, Cell and Developmental Biology
LIFS6410G	Seminar Enrichment Course

LIFS4981	Biochemistry and Cell Biology Project Research II
LIFS5260	Biochemical and Molecular Basis of Diseases
LIFS6115G	Current Topics in Development and Systems Biology
LIFS6410F	Seminar Enrichment Course

No Teaching Assignments

Research Postgraduate (RPG) Supervision

From January 2022 to December 2025 (As of 01 April 2025)

All Supervisions Current RPGs Graduated RPGs

Current RPGs

Doctor of Philosophy

YANG, Fengyuan
Life Science
LIAO, Yuanyuan
Life Science
HUANG, Rui
Life Science
LI, Yunbo
Life Science
ZHAO, Yanjing
Life Science
PAN, Hongru
Life Science
YANG, Chen
Life Science
ZHU, Hao
Life Science

Master of Philosophy

CHEN, Zhe
Life Science

Graduated RPGs

Doctor of Philosophy

DENG, Mingxi
Life Science( Completed in 2023 )
WANG, Ying
Life Science( Completed in 2022 )
YANG, Yang
Life Science( Completed in 2022 )

Master of Philosophy

HE, Jingjing
Life Science( Completed in 2023 )
LIN, Yisha
Life Science( Completed in 2022 )

Projects

From January 2023 to December 2025

All Projects 5 Leading Projects 3 Participating Projects 2

Investigation of Unpaired 2 as a novel cell competition factor

一種細胞間新競爭因子Unpaired 2的作用機制研究 Leading

RGC - General Research Fund
Project Team (HKUST)
YAN Yan (Lead)
2024 -
Stem cell-niche interactions in tissue maintenance and engineering

幹細胞與微環境互作在組織維持和組織工程中的應用 Participating

RGC - Theme-based Research Scheme
Project Team (HKUST)
XIE Ting (Lead)

CHEUNG Tom

GUO Yusong

LEUNG Danny Chi Yeu

LIU Kai

MAK Ho Yi

SUN Fei

WU Angela Ruohao

WU Zhenguo

YAN Yan
2022 -
The crosstalk between the fat body and imaginal disc tumors suppresses tumor growth in a Drosophila tumor model

果蠅脂肪組織對成蟲盤腫瘤的抑制作用機理探究 Leading

RGC - General Research Fund
Project Team (HKUST)
YAN Yan (Lead)
2020 - 2024
Construction of an optogenetic system for precise control of Notch signaling

基2020N365 對Notch信號通路進行精準量化調控的光遺傳學體系的研究 Leading

Shenzhen Science and Technology Innovation Committee
Project Team (HKUST)
YAN Yan (Lead)
2020 - 2023
Hong Kong Branch of National Engineering Research Center for Tissue Restoration & Reconstruction

國家人體組織功能重建工程技術研究中心香港分中心 Participating

Innovation and Technology Fund
Project Team (HKUST)
SUN Jianwei (Lead)

CHAU Ying

GUO Zhihong

HSING I-ming

IP Nancy Yuk-Yu

JIA Guocheng

KO Robert Kam Ming

KWOK Ryan Tsz Kin

LAM Wing Yip

LIANG Chun

LIN Nian

LUO Zhengtang

MI Yongli

TANG Benzhong

TSIM Karl Wah Keung

WILLIAMS Ian Duncan

WU Hongkai

WU Zhenguo

YAN Henry He

YAN Yan

YANG Jinglei

YAO Shuhuai
2015 -

Research Interest

Publications

2024 4

2023 1

2022 1

2020 2

2019 3

2018 2

2017 5

2016 2

2015 2

2014 2

2011 2

2010 1

2009 1

Article 3

Conference paper 1

Article 1

Article 1

Article 2

Article 3

Article 1

Conference paper 1

Article 1

Conference paper 4

Conference paper 2

Article 1

Conference paper 1

Article 1

Conference paper 1

Article 2

Article 1

Article 1

2019 3

2018 2

2017 5

2016 2

2015 2

2014 2

2011 2

2010 1

2009 1

Teaching Assignment

Research Postgraduate (RPG) Supervision

From January 2022 to December 2025 (As of 01 April 2025)

Current RPGs

Graduated RPGs

Projects

From January 2023 to December 2025

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