Faculty Profiles - CHEN Xiangke | The Hong Kong University of Science and Technology

Xiangke CHEN
陳相可

PhD in Biomedical Sciences
The University of Hong Kong, 2021

Research Assistant Professor
Division of Life Science

(852) 2358 7345
xkchen@ust.hk
Room 6201H

ORCID

0000-0003-2069-6634

ResearcherID

DWH-9273-2022

Scopus ID

57218589474

Research Interest Publications

Research Interest

Developmental biology
Gerontology
Neurodegenerative and age-related disorders

Publications

All Years 20 2024 1 2023 3 2022 5 2021 3 2020 3 2019 0 2018 5

2024 1

Effect of Physical Exercise-Based Rehabilitation on Long COVID: A Systematic Review and Meta-analysis

Medicine & Science in Sports & Exercise, v. 56, (1), January 2024, p. 143-154
Zheng, Chen; Chen, Xiangke; Sit, Cindy Hui Ping; Liang, Xiao; Li, Ming Hui; Ma, Alvin Chun-Hang; Wong, Stephen Heung-Sang
Article

2023 3

Association of Sedentary Lifestyle with Risk of Acute and Post-Acute COVID-19 Sequelae: A Retrospective Cohort Study

The American Journal of Medicine, December 2023
Zheng, Chen; Huang, Wendy Ya-Jun; Sun, Feng-Hua; Wong, Martin Chi-Sang; Siu, Parco Ming-Fai; Chen, Xiangke; Wong, Stephen Heung-Sang
Article

Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis

Autophagy, November 2023
Chen, Xiangke; Yi, Zhen-Ni; Lau, Jack Jark-Yin; Ma, Alvin Chun-Hang
Article

Does Exercise Regulate Autophagy in Humans? A Systematic Review and Meta-Analysis

Autophagy Reports, v. 2, (1), March 2023, article number 2190202
Chen, Xiangke; Zheng, Chen; Siu, Parco Ming-Fai; Sun, Feng-Hua; Wong, Stephen Heung-Sang; Ma, Alvin Chun-Hang
Article

2022 5

Does the gut microbiota contribute to the antiobesity effect of exercise? A systematic review and meta-analysis

Obesity, v. 30, (2), February 2022, p. 407-423
Zheng, Chen; Chen, Xiangke; Tian, Xiao Yu; Ma, Alvin Chun-Hang; Wong, Stephen Heung-Sang
Article

Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)

Experimental and Molecular Medicine, v. 54, (7), July 2022, p. 973-987
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Wong, Gordon Tin-Chun; Yi, Zhen-Ni; Ma, Alvin Chun-Hang; Chang, Raymond Chuen-Chung
Article

Modeling leukemia with zebrafish (Danio rerio): Towards precision medicine

Experimental Cell Research, v. 421, (2), 15 December 2022, article number 113401
Yi, Zhen-Ni; Chen, Xiangke; Ma, Alvin Chun-Hang
Article

Moderate-vigorous physical activity attenuates premature senescence of immune cells in sedentary adults with obesity: a pilot randomized controlled trial

Aging, v. 14, (24), December 2022, p. 10137-10152
Chen, Xiangke; Zheng, Chen; Wong, Stephen Heung-Sang; Ma, Alvin Chun-Hang
Article

The Effect of 12,000 Steps Daily Walking on Cardiometabolic Biomarkers in Sedentary Adults with Obesity

Medicine & Science in Sports & Exercise, v. 54, (9S), September 2022, p. 499
Zheng, Chen; Chen, Xiangke; Tian, Xiao Yu; Wong, Stephen H.S.
Conference paper

2021 3

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

Autophagy, v. 17, (5), May 2021, p. 1222-1231
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Chang, Raymond Chuen-Chung; Ma, Alvin Chun-Hang
Article

Is exercise a senolytic medicine? A systematic review

Aging Cell, v. 20, (1), January 2021, article number e13294
Chen, Xiangke; Yi, Zhen-Ni; Wong, Gordon Tin-Chun; Hasan, Kazi Md. Mahmudul; Kwan, Joseph Shiu-Kwong; Ma, Alvin Chun-Hang; Chang, Raymond Chuen-Chung
Article

Gut Microbiota-dependent Effects of Exercise on Obesity: A Systematic Review and Meta-analysis

Medicine & Science in Sports & Exercise, v. 53, (8S), August 2021, p. 293
Chen, Xiangke; Chen, Zheng; Tian, Xiao Yu; Wong, Stephen H.S.
Conference paper

2020 3

Covid-19 pandemic brings a sedentary lifestyle in young adults: A cross-sectional and longitudinal study

International Journal of Environmental Research and Public Health, v. 17, (17), September 2020, article number 6035, p. 1-11
Zheng, Chen; Huang, Wendy Yajun; Sheridan, Sinead; Sit, Cindy Hui-Ping; Chen, Xiangke; Wong, Stephen Heung-Sang
Article

Monoallelic Mutations in CC2D1A Suggest a Novel Role in Human Heterotaxy and Ciliary Dysfunction

Circulation: Genomic and Precision Medicine, v. 13, (6), December 2020, article number e003000, p. 696-706
Ma, Alvin Chun Hang; Mak, Christopher Chun Yu; Yeung, Kit San; Pei, Steven Lim Cho; Ying, Dingge; Yu, Mullin Ho Chung; Hasan, Kazi Md Mahmudul; Chen, Xiangke; Chow, Pak Cheong; Cheung, Yiu Fai; Chung, Brian Hon Yin
Article

Influence of systemic immune responses in the brain after wound injury of tail amputation in zebrafish

Alzheimer’s & Dementia, v. 16, (S3), December 2020, article number e047639, Supplement: Basic Science and Pathogenesis – Part 2
Chen, Xiangke; Ma, Alvin Chun-Hang; Chang, Raymond Chuen-Chung
Conference paper

2018 2

Acute glutamine ingestion modulates lymphocytic responses to exhaustive exercise in the heat

Applied Physiology, Nutrition, and Metabolism, v. 43, (3), March 2018, p. 213-220
Zheng, Chen; Chen, Xiangke; Zhou, Yue
Article

Fatigability in old zebrafish (Danio rerio): from exercise tolerance to exhaustion recovery

Hong Kong Medical Journal, v. 24, (Suppl 1), February 2018, p. 14, abstract no. 7
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Wong, Gordon Tin-Chun; Yip, B.
Conference paper

2017 3

Effect of 2-week Cold-water Swimming on White Adipose Tissue Browning in Mice

Medicine & Science in Sports & Exercise, v. 49, (5S), May 2017, p. 438
Zheng, Chen; Chen, Xiangke; Wu, Chung-Hsin; Wong, Stephen Heung-Sang
Conference paper

Oral treatment with herbal formula B307 alleviates skeletal muscle atrophy from hind-limb unloading

Hong Kong Medical Journal, v. 23, (Suppl 1), February 2017, p. 12, abstract no. 5
Chen, Xiangke; Zheng, Chen; Wu, C.H.; Kwan, Joseph Shiu-Kwong
Conference paper

TNF-α-mediated inflammatory apoptosis and angiogenesis in physical inactivity-induced muscle atrophy

Journal of Cachexia, Sarcopenia and Muscle, v. 8, (6), December 2017, p. 1031
Chen, Xiangke; Zheng, Chen; Kwan, Joseph Shiu Kwong
Conference paper

Article 1

Effect of Physical Exercise-Based Rehabilitation on Long COVID: A Systematic Review and Meta-analysis

Medicine & Science in Sports & Exercise, v. 56, (1), January 2024, p. 143-154
Zheng, Chen; Chen, Xiangke; Sit, Cindy Hui Ping; Liang, Xiao; Li, Ming Hui; Ma, Alvin Chun-Hang; Wong, Stephen Heung-Sang

Article 3

Association of Sedentary Lifestyle with Risk of Acute and Post-Acute COVID-19 Sequelae: A Retrospective Cohort Study

The American Journal of Medicine, December 2023
Zheng, Chen; Huang, Wendy Ya-Jun; Sun, Feng-Hua; Wong, Martin Chi-Sang; Siu, Parco Ming-Fai; Chen, Xiangke; Wong, Stephen Heung-Sang

Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis

Autophagy, November 2023
Chen, Xiangke; Yi, Zhen-Ni; Lau, Jack Jark-Yin; Ma, Alvin Chun-Hang

Does Exercise Regulate Autophagy in Humans? A Systematic Review and Meta-Analysis

Autophagy Reports, v. 2, (1), March 2023, article number 2190202
Chen, Xiangke; Zheng, Chen; Siu, Parco Ming-Fai; Sun, Feng-Hua; Wong, Stephen Heung-Sang; Ma, Alvin Chun-Hang

Article 4

Does the gut microbiota contribute to the antiobesity effect of exercise? A systematic review and meta-analysis

Obesity, v. 30, (2), February 2022, p. 407-423
Zheng, Chen; Chen, Xiangke; Tian, Xiao Yu; Ma, Alvin Chun-Hang; Wong, Stephen Heung-Sang

Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)

Experimental and Molecular Medicine, v. 54, (7), July 2022, p. 973-987
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Wong, Gordon Tin-Chun; Yi, Zhen-Ni; Ma, Alvin Chun-Hang; Chang, Raymond Chuen-Chung

Modeling leukemia with zebrafish (Danio rerio): Towards precision medicine

Experimental Cell Research, v. 421, (2), 15 December 2022, article number 113401
Yi, Zhen-Ni; Chen, Xiangke; Ma, Alvin Chun-Hang

Moderate-vigorous physical activity attenuates premature senescence of immune cells in sedentary adults with obesity: a pilot randomized controlled trial

Aging, v. 14, (24), December 2022, p. 10137-10152
Chen, Xiangke; Zheng, Chen; Wong, Stephen Heung-Sang; Ma, Alvin Chun-Hang

Conference paper 1

The Effect of 12,000 Steps Daily Walking on Cardiometabolic Biomarkers in Sedentary Adults with Obesity

Medicine & Science in Sports & Exercise, v. 54, (9S), September 2022, p. 499
Zheng, Chen; Chen, Xiangke; Tian, Xiao Yu; Wong, Stephen H.S.

Article 2

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

Autophagy, v. 17, (5), May 2021, p. 1222-1231
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Chang, Raymond Chuen-Chung; Ma, Alvin Chun-Hang

Is exercise a senolytic medicine? A systematic review

Aging Cell, v. 20, (1), January 2021, article number e13294
Chen, Xiangke; Yi, Zhen-Ni; Wong, Gordon Tin-Chun; Hasan, Kazi Md. Mahmudul; Kwan, Joseph Shiu-Kwong; Ma, Alvin Chun-Hang; Chang, Raymond Chuen-Chung

Conference paper 1

Gut Microbiota-dependent Effects of Exercise on Obesity: A Systematic Review and Meta-analysis

Medicine & Science in Sports & Exercise, v. 53, (8S), August 2021, p. 293
Chen, Xiangke; Chen, Zheng; Tian, Xiao Yu; Wong, Stephen H.S.

Article 2

Covid-19 pandemic brings a sedentary lifestyle in young adults: A cross-sectional and longitudinal study

International Journal of Environmental Research and Public Health, v. 17, (17), September 2020, article number 6035, p. 1-11
Zheng, Chen; Huang, Wendy Yajun; Sheridan, Sinead; Sit, Cindy Hui-Ping; Chen, Xiangke; Wong, Stephen Heung-Sang

Monoallelic Mutations in CC2D1A Suggest a Novel Role in Human Heterotaxy and Ciliary Dysfunction

Circulation: Genomic and Precision Medicine, v. 13, (6), December 2020, article number e003000, p. 696-706
Ma, Alvin Chun Hang; Mak, Christopher Chun Yu; Yeung, Kit San; Pei, Steven Lim Cho; Ying, Dingge; Yu, Mullin Ho Chung; Hasan, Kazi Md Mahmudul; Chen, Xiangke; Chow, Pak Cheong; Cheung, Yiu Fai; Chung, Brian Hon Yin

Conference paper 1

Influence of systemic immune responses in the brain after wound injury of tail amputation in zebrafish

Alzheimer’s & Dementia, v. 16, (S3), December 2020, article number e047639, Supplement: Basic Science and Pathogenesis – Part 2
Chen, Xiangke; Ma, Alvin Chun-Hang; Chang, Raymond Chuen-Chung

Article 1

Acute glutamine ingestion modulates lymphocytic responses to exhaustive exercise in the heat

Applied Physiology, Nutrition, and Metabolism, v. 43, (3), March 2018, p. 213-220
Zheng, Chen; Chen, Xiangke; Zhou, Yue

Conference paper 1

Fatigability in old zebrafish (Danio rerio): from exercise tolerance to exhaustion recovery

Hong Kong Medical Journal, v. 24, (Suppl 1), February 2018, p. 14, abstract no. 7
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Wong, Gordon Tin-Chun; Yip, B.

Conference paper 3

Effect of 2-week Cold-water Swimming on White Adipose Tissue Browning in Mice

Medicine & Science in Sports & Exercise, v. 49, (5S), May 2017, p. 438
Zheng, Chen; Chen, Xiangke; Wu, Chung-Hsin; Wong, Stephen Heung-Sang

Oral treatment with herbal formula B307 alleviates skeletal muscle atrophy from hind-limb unloading

Hong Kong Medical Journal, v. 23, (Suppl 1), February 2017, p. 12, abstract no. 5
Chen, Xiangke; Zheng, Chen; Wu, C.H.; Kwan, Joseph Shiu-Kwong

TNF-α-mediated inflammatory apoptosis and angiogenesis in physical inactivity-induced muscle atrophy

Journal of Cachexia, Sarcopenia and Muscle, v. 8, (6), December 2017, p. 1031
Chen, Xiangke; Zheng, Chen; Kwan, Joseph Shiu Kwong

2018 2

Acute glutamine ingestion modulates lymphocytic responses to exhaustive exercise in the heat

Applied Physiology, Nutrition, and Metabolism, v. 43, (3), March 2018, p. 213-220
Zheng, Chen; Chen, Xiangke; Zhou, Yue
Article

Fatigability in old zebrafish (Danio rerio): from exercise tolerance to exhaustion recovery

Hong Kong Medical Journal, v. 24, (Suppl 1), February 2018, p. 14, abstract no. 7
Chen, Xiangke; Kwan, Joseph Shiu-Kwong; Wong, Gordon Tin-Chun; Yip, B.
Conference paper

2017 3

Effect of 2-week Cold-water Swimming on White Adipose Tissue Browning in Mice

Medicine & Science in Sports & Exercise, v. 49, (5S), May 2017, p. 438
Zheng, Chen; Chen, Xiangke; Wu, Chung-Hsin; Wong, Stephen Heung-Sang
Conference paper

Oral treatment with herbal formula B307 alleviates skeletal muscle atrophy from hind-limb unloading

Hong Kong Medical Journal, v. 23, (Suppl 1), February 2017, p. 12, abstract no. 5
Chen, Xiangke; Zheng, Chen; Wu, C.H.; Kwan, Joseph Shiu-Kwong
Conference paper

TNF-α-mediated inflammatory apoptosis and angiogenesis in physical inactivity-induced muscle atrophy

Journal of Cachexia, Sarcopenia and Muscle, v. 8, (6), December 2017, p. 1031
Chen, Xiangke; Zheng, Chen; Kwan, Joseph Shiu Kwong
Conference paper

No Publications

Research Interest

Publications

2024 1

2023 3

2022 5

2021 3

2020 3

2018 2

2017 3

Article 1

Article 3

Article 4

Conference paper 1

Article 2

Conference paper 1

Article 2

Conference paper 1

Article 1

Conference paper 1

Conference paper 3

2018 2

2017 3

Projects

From January 2022 to December 2024

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