Faculty Profiles - NGUYEN Tuan Anh | The Hong Kong University of Science and Technology

Tuan Anh NGUYEN

PhD in Biochemistry
Korea Advanced Institute of Science and Technology, 2012

Associate Professor
Division of Life Science

(852) 3469 2679
tuananh@ust.hk
Room 5513
Personal Web

ORCID

0000-0001-7793-2699

Scopus ID

57209165967

Research Interest Publications Projects Teaching Assignment RPG Supervision Space used

Research Interest

RNA interacting proteins and enzymes lab (RIPE Lab)
Chemical biology
Molecular biology
Structural biology

Publications

All Years 33 2024 3 2023 6 2022 2 2021 2 2020 4 2019 1 2018 15

2024 3

Determinants of selectivity in the dicing mechanism

Nature Communications, v. 15, (1), October 2024, article number 8989
Le, Thi Nhu Y; Le, Cong Truc; Nguyen, Tuan Anh
Article

High-throughput protocol for studying pri-miRNA processing using randomized sequences

STAR Protocols, v. 5, (1), March 2024, article number 102782
Le, Thi Nhu Y; Nguyen, Tuan Anh
Article

Two-motif model illuminates DICER cleavage preferences

Nucleic Acids Research, January 2024, article number gkad1186
Le, Cong Truc; Nguyen, Trung Duc; Nguyen, Tuan Anh
Article

2023 6

Dissection of the Caenorhabditis Elegans Microprocessor

Nucleic Acids Research, v. 51, (4), 28 February 2023, p. 1512-1527
Nguyen, Thuy Linh; Nguyen, Trung Duc; Ngo, Minh Khoa; Nguyen, Tuan Anh
Article

miR-148a-3p and DDX6 functional link promotes survival of myeloid leukemia cells

Blood Advances, v. 7, (15), August 2023, p. 3846-3861
Ghashghaei, Maryam; Le, Cong Truc; Shaalan, Haya; Escano, Leo; Yue, Marty; Arsalan, Aaremish; Rouhi, Arefeh; Nguyen, Tuan Anh; Vu, Ly P
Article

Noncanonical Processing by Animal Microprocessor

Molecular Cell, v. 83, (11), June 2023, p. 1810-1826.e8
Nguyen, Thuy Linh; Nguyen, Trung Duc; Ngo, Minh Khoa; Le, Thi Nhu Y; Nguyen, Tuan Anh
Article

SRSF7 and SRSF3 depend on RNA sequencing motifs and secondary structures to regulate Microprocessor

Life Science Alliance, v. 6, (4), April 2023, article number e202201779
Le, Minh Ngoc; Nguyen, Trung Duc; Nguyen, Tuan Anh
Article

Pri-miRNA cleavage assays for the Microprocessor complex

Methods in Enzymology / Cambridge, Massachusetts : Elsevier, 2023
Le, Thi Nhu Y; Le, Cong Truc; Nguyen, Tuan Anh
Book chapter

The pre-miRNA cleavage assays for DICER

Methods in Enzymology / Cambridge, Massachusetts : Elsevier, 2023
Le, Cong Truc; Le, Thi Nhu Y; Nguyen, Tuan Anh
Book chapter

2022 2

Intramolecular ligation method (iLIME) for pre-miRNA quantification and sequencing

RNA, v. 28, (7), July 2022, p. 1028-1038
Le, Minh Ngoc; Le, Cong Truc; Nguyen, Tuan Anh
Article

Secondary structure RNA elements control the cleavage activity of DICER

Nature Communications, v. 13, (1), April 2022, article number 2138
Nguyen, Trung Duc; Trinh, Tam Anh; Bao, Sheng; Nguyen, Tuan Anh
Article

2021 2

Bulges control pri-miRNA processing in a position and strand-dependent manner

RNA biology, 31 December 2020
Li, Shaohua; Le, Thi Nhu Y; Nguyen, Trung Duc; Trinh, Tam Anh; Nguyen, Tuan Anh
Article

The conserved single-cleavage mechanism of animal DROSHA enzymes

Communications Biology, v. 4, (1), December 2021, article number 1332
Nguyen, Thuy Linh; Nguyen, Trung Duc; Nguyen, Tuan Anh
Article

2020 4

Human disease-associated single nucleotide polymorphism changes the orientation of DROSHA on pri-mir-146a

RNA, v. 26, (12), December 2020, p. 1777-1786
Le, Cong Truc; Nguyen, Thuy Linh; Nguyen, Trung Duc; Nguyen, Tuan Anh
Article

Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor

Nature Communications, v. 11, (1), December 2020, article number 1926
Li, Shaohua; Nguyen, Trung Duc; Nguyen, Thuy Linh; Nguyen, Tuan Anh
Article

Select Amino Acids in DGCR8 Are Essential for the UGU-pri-miRNA Interaction and Processing

Communications Biology, v. 3, July 2020, article number 244
Dang, Thi Lieu; Le, Cong Truc; Le, Minh Ngoc; Nguyen, Trung Duc; Nguyen, Thuy Linh; Bao, Sheng; Li, Shaohua; Nguyen, Tuan Anh
Article

The Internal Loops in the Lower Stem of Primary MicroRNA Transcripts Facilitate Single Cleavage of Human Microprocessor

Nucleic Acids Research, v. 48, (5), March 2020, p. 2579-2593
Nguyen, Thuy Linh; Nguyen, Trung Duc; Bao, Sheng; Li, Shaohua; Nguyen, Tuan Anh
Article

2019 1

Orientation of Human Microprocessor on Primary MicroRNAs

Biochemistry, v. 58, (4), January 2019, p. 189-198
Nguyen, Huong Minh; Nguyen, Trung Duc; Nguyen, Thuy Linh; Nguyen, Tuan Anh
Article

2018 2

Microprocessor Depends on Hemin to Recognize the Apical Loop of Primary MicroRNA

Nucleic Acids Research, v. 46, (11), June 2018, p. 5726-5736
Nguyen, Tuan Anh; Park, Joha; Dang, Thi Lieu; Choi, Yeon-Gil; Kim, Narry
Article

SRSF₃ recruits DROSHA to the basal junction of primary microRNAs

RNA, v. 24, (7), July 2018, p. 892-898
Kim, Kijun; Nguyen, Trung Duc; Li, Shaohua; Nguyen, Tuan Anh
Article

2016 1

Structure of Human DROSHA

Cell, v. 164, (1-2), January 2016, p. 81-90
Kwon, S. Chul; Nguyen, Tuan Anh; Choi, Yeongil; Jo, Myunghyun; Hohng, Sungchul C.; Kim, V. Narry; Woo, Jae-Sung
Article

2015 3

A Physiological Significance Of The Functional Interaction Between Mus81 And Rad27 In Homologous Recombination Repair

Nucleic Acids Research, v. 43, (3), 2015, p. 1684-1699
Thu, Huong Phung Thi; Nguyen, Tuan Anh; Munashingha, Palinda Ruvan; Kwon, Buki; Van, Quydao; Seo, Yeonsoo
Article

Functional Anatomy of the Human Microprocessor

Cell, v. 161, (6), June 2015, p. 1374-1387
Nguyen, Tuan Anh; Jo, Myunghyun; Choi, Yeongil; Park, Joha; Kwon, S. Chul; Hohng, Sungchul C.; Kim, V. Narry; Woo, Jae-Sung
Article

How Human Microprocessor Recognizes Primary MicroRNAs and Finds the Correct Cleavage Sites

Biodesign, v. 3, (2), June 2015, p. 77-87
Nguyen, Tuan Anh; Kwon, S. Chul; Woo, Jae-Sung
Article

2014 1

Adenylation of Maternally Inherited MicroRNAs by Wispy

Molecular Cell, v. 56, (5), December 2014, p. 696-707
Lee, Mihye; Choi, Yeon; Kim, Kijun; Jin, Hua; Lim, Jaechul; Nguyen, Tuan Anh; Yang, Jihye; Jeong, Minsun; Giráldez, Antonio J.; Yang, Hui; Patel, Dinshaw J.; Kim, V. Narry
Article

2012 3

Biochemical Studies Of The Saccharomyces Cerevisiae Mph1 Helicase On Junction-Containing DNA Structures

Nucleic Acids Research, v. 40, (5), March 2012, p. 2089-2106
Kang, Young-Hoon; Munashingha, Palinda Ruvan; Lee, Chul-Hwan; Nguyen, Tuan Anh; Seo, Yeon-Soo
Article

Human Mus81 Complexes Stimulate Flap Endonuclease 1

FEBS Journal, v. 279, (13), July 2012, p. 2412-2430
Shin, Yong-keol; Amangyeld, Tamir; Nguyen, Tuan Anh; Munashingha, Palinda Ruvan; Seo, Yeon-soo
Article

The Trans-autostimulatory Activity of Rad27 Suppresses DNA2 Defects in Okazaki Fragment Processing

Journal of Biological Chemistry, v. 287, (12), March 2012, p. 8675-8687
Munashingha, Palinda Ruvan; Lee, Chul-Hwan; Kang, Young-Hoon; Shin, Yongkeol; Nguyen, Tuan Anh; Seo, Yeon-soo
Article

2011 2

Analysis of Subunit Assembly and Function of the Saccharomyces Cerevisiae RNase H2 Complex

The FEBS Journal, v. 278, (24), December 2011, p. 4927-4942
Nguyen, Tuan Anh; Tak, Yon-Soo; Lee, Chul-Hwan; Kang, Young-Hoon; Cho, Il-Taeg; Seo, Yeon-Soo
Article

Lagging Strand Synthesis and Genomic Stability

DNA Repair - On the Pathways to Fixing DNA Damage and Errors /Francesca Storici. Croatia: InTech, September 9, 2011 , chapter 1, p.1-24
Nguyen, Tuan Anh; Lee, Chul-Hwan; Seo, Yeonsoo
Book chapter

2010 1

Genetic and Functional Interactions Between Mus81-Mms4 and Rad27

Nucleic Acids Research, v. 38, (21), November 2010, p. 7611-7625
Kang, Min-Jung; Lee, Chul-Hwan; Kang, Young-Hoon; Cho, Ii-Taeg; Nguyen, Tuan Anh; Seo, Yeonsoo
Article

2009 2

Human Replication Factor C Stimulates Flap Endonuclease 1

Journal of Biological Chemistry, v. 284, (16), April 2009, p. 10387-10399
Cho, Ii-Taeg; Kim, Do-Hyung; Kang, Young-Hoon; Lee, Chul-Hwan; Amangyeld, Tamir; Nguyen, Tuan Anh; Hurwitz, Jerard; Seo, Yeonsoo
Article

Involvement of Vts1, a Structure-specific RNA-binding Protein, in Okazaki Fragment Processing in Yeast

Nucleic Acids Research, v. 38, (5), December 2009, article number gkp1135, p. 1583-1595
Lee, Chul-Hwan; Shin, Yongkeol; Phung, Thi Thu Huong; Bae, Jae Seok; Kang, Young-Hoon; Nguyen, Tuan Anh; Kim, Jeong-Hoon; Kim, Do-Hyung; Kang, Min-Jung; Bae, Sung-Ho; Seo, Yeonsoo
Article

Article 3

Determinants of selectivity in the dicing mechanism

Nature Communications, v. 15, (1), October 2024, article number 8989
Le, Thi Nhu Y; Le, Cong Truc; Nguyen, Tuan Anh

High-throughput protocol for studying pri-miRNA processing using randomized sequences

STAR Protocols, v. 5, (1), March 2024, article number 102782
Le, Thi Nhu Y; Nguyen, Tuan Anh

Two-motif model illuminates DICER cleavage preferences

Nucleic Acids Research, January 2024, article number gkad1186
Le, Cong Truc; Nguyen, Trung Duc; Nguyen, Tuan Anh

Article 4

Dissection of the Caenorhabditis Elegans Microprocessor

Nucleic Acids Research, v. 51, (4), 28 February 2023, p. 1512-1527
Nguyen, Thuy Linh; Nguyen, Trung Duc; Ngo, Minh Khoa; Nguyen, Tuan Anh

miR-148a-3p and DDX6 functional link promotes survival of myeloid leukemia cells

Blood Advances, v. 7, (15), August 2023, p. 3846-3861
Ghashghaei, Maryam; Le, Cong Truc; Shaalan, Haya; Escano, Leo; Yue, Marty; Arsalan, Aaremish; Rouhi, Arefeh; Nguyen, Tuan Anh; Vu, Ly P

Noncanonical Processing by Animal Microprocessor

Molecular Cell, v. 83, (11), June 2023, p. 1810-1826.e8
Nguyen, Thuy Linh; Nguyen, Trung Duc; Ngo, Minh Khoa; Le, Thi Nhu Y; Nguyen, Tuan Anh

SRSF7 and SRSF3 depend on RNA sequencing motifs and secondary structures to regulate Microprocessor

Life Science Alliance, v. 6, (4), April 2023, article number e202201779
Le, Minh Ngoc; Nguyen, Trung Duc; Nguyen, Tuan Anh

Book chapter 2

Pri-miRNA cleavage assays for the Microprocessor complex

Methods in Enzymology / Cambridge, Massachusetts : Elsevier, 2023
Le, Thi Nhu Y; Le, Cong Truc; Nguyen, Tuan Anh

The pre-miRNA cleavage assays for DICER

Methods in Enzymology / Cambridge, Massachusetts : Elsevier, 2023
Le, Cong Truc; Le, Thi Nhu Y; Nguyen, Tuan Anh

Article 2

Intramolecular ligation method (iLIME) for pre-miRNA quantification and sequencing

RNA, v. 28, (7), July 2022, p. 1028-1038
Le, Minh Ngoc; Le, Cong Truc; Nguyen, Tuan Anh

Secondary structure RNA elements control the cleavage activity of DICER

Nature Communications, v. 13, (1), April 2022, article number 2138
Nguyen, Trung Duc; Trinh, Tam Anh; Bao, Sheng; Nguyen, Tuan Anh

Article 2

Bulges control pri-miRNA processing in a position and strand-dependent manner

RNA biology, 31 December 2020
Li, Shaohua; Le, Thi Nhu Y; Nguyen, Trung Duc; Trinh, Tam Anh; Nguyen, Tuan Anh

The conserved single-cleavage mechanism of animal DROSHA enzymes

Communications Biology, v. 4, (1), December 2021, article number 1332
Nguyen, Thuy Linh; Nguyen, Trung Duc; Nguyen, Tuan Anh

Article 4

Human disease-associated single nucleotide polymorphism changes the orientation of DROSHA on pri-mir-146a

RNA, v. 26, (12), December 2020, p. 1777-1786
Le, Cong Truc; Nguyen, Thuy Linh; Nguyen, Trung Duc; Nguyen, Tuan Anh

Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor

Nature Communications, v. 11, (1), December 2020, article number 1926
Li, Shaohua; Nguyen, Trung Duc; Nguyen, Thuy Linh; Nguyen, Tuan Anh

Select Amino Acids in DGCR8 Are Essential for the UGU-pri-miRNA Interaction and Processing

Communications Biology, v. 3, July 2020, article number 244
Dang, Thi Lieu; Le, Cong Truc; Le, Minh Ngoc; Nguyen, Trung Duc; Nguyen, Thuy Linh; Bao, Sheng; Li, Shaohua; Nguyen, Tuan Anh

The Internal Loops in the Lower Stem of Primary MicroRNA Transcripts Facilitate Single Cleavage of Human Microprocessor

Nucleic Acids Research, v. 48, (5), March 2020, p. 2579-2593
Nguyen, Thuy Linh; Nguyen, Trung Duc; Bao, Sheng; Li, Shaohua; Nguyen, Tuan Anh

Article 1

Orientation of Human Microprocessor on Primary MicroRNAs

Biochemistry, v. 58, (4), January 2019, p. 189-198
Nguyen, Huong Minh; Nguyen, Trung Duc; Nguyen, Thuy Linh; Nguyen, Tuan Anh

Article 2

Microprocessor Depends on Hemin to Recognize the Apical Loop of Primary MicroRNA

Nucleic Acids Research, v. 46, (11), June 2018, p. 5726-5736
Nguyen, Tuan Anh; Park, Joha; Dang, Thi Lieu; Choi, Yeon-Gil; Kim, Narry

SRSF₃ recruits DROSHA to the basal junction of primary microRNAs

RNA, v. 24, (7), July 2018, p. 892-898
Kim, Kijun; Nguyen, Trung Duc; Li, Shaohua; Nguyen, Tuan Anh

Article 1

Structure of Human DROSHA

Cell, v. 164, (1-2), January 2016, p. 81-90
Kwon, S. Chul; Nguyen, Tuan Anh; Choi, Yeongil; Jo, Myunghyun; Hohng, Sungchul C.; Kim, V. Narry; Woo, Jae-Sung

Article 3

A Physiological Significance Of The Functional Interaction Between Mus81 And Rad27 In Homologous Recombination Repair

Nucleic Acids Research, v. 43, (3), 2015, p. 1684-1699
Thu, Huong Phung Thi; Nguyen, Tuan Anh; Munashingha, Palinda Ruvan; Kwon, Buki; Van, Quydao; Seo, Yeonsoo

Functional Anatomy of the Human Microprocessor

Cell, v. 161, (6), June 2015, p. 1374-1387
Nguyen, Tuan Anh; Jo, Myunghyun; Choi, Yeongil; Park, Joha; Kwon, S. Chul; Hohng, Sungchul C.; Kim, V. Narry; Woo, Jae-Sung

How Human Microprocessor Recognizes Primary MicroRNAs and Finds the Correct Cleavage Sites

Biodesign, v. 3, (2), June 2015, p. 77-87
Nguyen, Tuan Anh; Kwon, S. Chul; Woo, Jae-Sung

Article 1

Adenylation of Maternally Inherited MicroRNAs by Wispy

Molecular Cell, v. 56, (5), December 2014, p. 696-707
Lee, Mihye; Choi, Yeon; Kim, Kijun; Jin, Hua; Lim, Jaechul; Nguyen, Tuan Anh; Yang, Jihye; Jeong, Minsun; Giráldez, Antonio J.; Yang, Hui; Patel, Dinshaw J.; Kim, V. Narry

Article 3

Biochemical Studies Of The Saccharomyces Cerevisiae Mph1 Helicase On Junction-Containing DNA Structures

Nucleic Acids Research, v. 40, (5), March 2012, p. 2089-2106
Kang, Young-Hoon; Munashingha, Palinda Ruvan; Lee, Chul-Hwan; Nguyen, Tuan Anh; Seo, Yeon-Soo

Human Mus81 Complexes Stimulate Flap Endonuclease 1

FEBS Journal, v. 279, (13), July 2012, p. 2412-2430
Shin, Yong-keol; Amangyeld, Tamir; Nguyen, Tuan Anh; Munashingha, Palinda Ruvan; Seo, Yeon-soo

The Trans-autostimulatory Activity of Rad27 Suppresses DNA2 Defects in Okazaki Fragment Processing

Journal of Biological Chemistry, v. 287, (12), March 2012, p. 8675-8687
Munashingha, Palinda Ruvan; Lee, Chul-Hwan; Kang, Young-Hoon; Shin, Yongkeol; Nguyen, Tuan Anh; Seo, Yeon-soo

Article 1

Analysis of Subunit Assembly and Function of the Saccharomyces Cerevisiae RNase H2 Complex

The FEBS Journal, v. 278, (24), December 2011, p. 4927-4942
Nguyen, Tuan Anh; Tak, Yon-Soo; Lee, Chul-Hwan; Kang, Young-Hoon; Cho, Il-Taeg; Seo, Yeon-Soo

Book chapter 1

Lagging Strand Synthesis and Genomic Stability

DNA Repair - On the Pathways to Fixing DNA Damage and Errors /Francesca Storici. Croatia: InTech, September 9, 2011 , chapter 1, p.1-24
Nguyen, Tuan Anh; Lee, Chul-Hwan; Seo, Yeonsoo

Article 1

Genetic and Functional Interactions Between Mus81-Mms4 and Rad27

Nucleic Acids Research, v. 38, (21), November 2010, p. 7611-7625
Kang, Min-Jung; Lee, Chul-Hwan; Kang, Young-Hoon; Cho, Ii-Taeg; Nguyen, Tuan Anh; Seo, Yeonsoo

Article 2

Human Replication Factor C Stimulates Flap Endonuclease 1

Journal of Biological Chemistry, v. 284, (16), April 2009, p. 10387-10399
Cho, Ii-Taeg; Kim, Do-Hyung; Kang, Young-Hoon; Lee, Chul-Hwan; Amangyeld, Tamir; Nguyen, Tuan Anh; Hurwitz, Jerard; Seo, Yeonsoo

Involvement of Vts1, a Structure-specific RNA-binding Protein, in Okazaki Fragment Processing in Yeast

Nucleic Acids Research, v. 38, (5), December 2009, article number gkp1135, p. 1583-1595
Lee, Chul-Hwan; Shin, Yongkeol; Phung, Thi Thu Huong; Bae, Jae Seok; Kang, Young-Hoon; Nguyen, Tuan Anh; Kim, Jeong-Hoon; Kim, Do-Hyung; Kang, Min-Jung; Bae, Sung-Ho; Seo, Yeonsoo

2018 2

Microprocessor Depends on Hemin to Recognize the Apical Loop of Primary MicroRNA

Nucleic Acids Research, v. 46, (11), June 2018, p. 5726-5736
Nguyen, Tuan Anh; Park, Joha; Dang, Thi Lieu; Choi, Yeon-Gil; Kim, Narry
Article

SRSF₃ recruits DROSHA to the basal junction of primary microRNAs

RNA, v. 24, (7), July 2018, p. 892-898
Kim, Kijun; Nguyen, Trung Duc; Li, Shaohua; Nguyen, Tuan Anh
Article

2016 1

Structure of Human DROSHA

Cell, v. 164, (1-2), January 2016, p. 81-90
Kwon, S. Chul; Nguyen, Tuan Anh; Choi, Yeongil; Jo, Myunghyun; Hohng, Sungchul C.; Kim, V. Narry; Woo, Jae-Sung
Article

2015 3

A Physiological Significance Of The Functional Interaction Between Mus81 And Rad27 In Homologous Recombination Repair

Nucleic Acids Research, v. 43, (3), 2015, p. 1684-1699
Thu, Huong Phung Thi; Nguyen, Tuan Anh; Munashingha, Palinda Ruvan; Kwon, Buki; Van, Quydao; Seo, Yeonsoo
Article

Functional Anatomy of the Human Microprocessor

Cell, v. 161, (6), June 2015, p. 1374-1387
Nguyen, Tuan Anh; Jo, Myunghyun; Choi, Yeongil; Park, Joha; Kwon, S. Chul; Hohng, Sungchul C.; Kim, V. Narry; Woo, Jae-Sung
Article

How Human Microprocessor Recognizes Primary MicroRNAs and Finds the Correct Cleavage Sites

Biodesign, v. 3, (2), June 2015, p. 77-87
Nguyen, Tuan Anh; Kwon, S. Chul; Woo, Jae-Sung
Article

2014 1

Adenylation of Maternally Inherited MicroRNAs by Wispy

Molecular Cell, v. 56, (5), December 2014, p. 696-707
Lee, Mihye; Choi, Yeon; Kim, Kijun; Jin, Hua; Lim, Jaechul; Nguyen, Tuan Anh; Yang, Jihye; Jeong, Minsun; Giráldez, Antonio J.; Yang, Hui; Patel, Dinshaw J.; Kim, V. Narry
Article

2012 3

Biochemical Studies Of The Saccharomyces Cerevisiae Mph1 Helicase On Junction-Containing DNA Structures

Nucleic Acids Research, v. 40, (5), March 2012, p. 2089-2106
Kang, Young-Hoon; Munashingha, Palinda Ruvan; Lee, Chul-Hwan; Nguyen, Tuan Anh; Seo, Yeon-Soo
Article

Human Mus81 Complexes Stimulate Flap Endonuclease 1

FEBS Journal, v. 279, (13), July 2012, p. 2412-2430
Shin, Yong-keol; Amangyeld, Tamir; Nguyen, Tuan Anh; Munashingha, Palinda Ruvan; Seo, Yeon-soo
Article

The Trans-autostimulatory Activity of Rad27 Suppresses DNA2 Defects in Okazaki Fragment Processing

Journal of Biological Chemistry, v. 287, (12), March 2012, p. 8675-8687
Munashingha, Palinda Ruvan; Lee, Chul-Hwan; Kang, Young-Hoon; Shin, Yongkeol; Nguyen, Tuan Anh; Seo, Yeon-soo
Article

2011 2

Analysis of Subunit Assembly and Function of the Saccharomyces Cerevisiae RNase H2 Complex

The FEBS Journal, v. 278, (24), December 2011, p. 4927-4942
Nguyen, Tuan Anh; Tak, Yon-Soo; Lee, Chul-Hwan; Kang, Young-Hoon; Cho, Il-Taeg; Seo, Yeon-Soo
Article

Lagging Strand Synthesis and Genomic Stability

DNA Repair - On the Pathways to Fixing DNA Damage and Errors /Francesca Storici. Croatia: InTech, September 9, 2011 , chapter 1, p.1-24
Nguyen, Tuan Anh; Lee, Chul-Hwan; Seo, Yeonsoo
Book chapter

2010 1

Genetic and Functional Interactions Between Mus81-Mms4 and Rad27

Nucleic Acids Research, v. 38, (21), November 2010, p. 7611-7625
Kang, Min-Jung; Lee, Chul-Hwan; Kang, Young-Hoon; Cho, Ii-Taeg; Nguyen, Tuan Anh; Seo, Yeonsoo
Article

2009 2

Human Replication Factor C Stimulates Flap Endonuclease 1

Journal of Biological Chemistry, v. 284, (16), April 2009, p. 10387-10399
Cho, Ii-Taeg; Kim, Do-Hyung; Kang, Young-Hoon; Lee, Chul-Hwan; Amangyeld, Tamir; Nguyen, Tuan Anh; Hurwitz, Jerard; Seo, Yeonsoo
Article

Involvement of Vts1, a Structure-specific RNA-binding Protein, in Okazaki Fragment Processing in Yeast

Nucleic Acids Research, v. 38, (5), December 2009, article number gkp1135, p. 1583-1595
Lee, Chul-Hwan; Shin, Yongkeol; Phung, Thi Thu Huong; Bae, Jae Seok; Kang, Young-Hoon; Nguyen, Tuan Anh; Kim, Jeong-Hoon; Kim, Do-Hyung; Kang, Min-Jung; Bae, Sung-Ho; Seo, Yeonsoo
Article

Teaching Assignment

2024-25 Fall 2 2023-24 Summer 1 2023-24 Spring 5 2023-24 Winter 0 2023-24 Fall 7 2022-23 Summer 1

LIFS3110	Biotechnological Application of Recombinant DNA Techniques
LIFS6113H	Current Topics in Biochemistry and Biophysics

BTEC5210

Principles and Application in Biotechnology

BIBU4850	Biotechnology and Business Project Research
LIFS4884	Application of RNA Technology to Human Diseases
LIFS4961	Biochemistry and Cell Biology Capstone Project
LIFS4983	Biotechnology Project Research II
LIFS6660	Molecular Medicine

BIBU4850	Biotechnology and Business Project Research
LIFS3110	Biotechnological Application of Recombinant DNA Techniques
LIFS4961	Biochemistry and Cell Biology Capstone Project
LIFS4973	Biotechnology Project Research I
LIFS6111S	Life Science Postgraduate Student Seminar
LIFS6113G	Current Topics in Biochemistry and Biophysics
SCIE3900	International Research Experience

BTEC5210

Principles and Application in Biotechnology

No Teaching Assignments

Research Postgraduate (RPG) Supervision

From January 2021 to December 2024 (As of 21 November 2024)

All Supervisions Current RPGs Graduated RPGs

Current RPGs

Doctor of Philosophy

NGO, Minh Khoa
Life Science
LE, Thi Nhu Y
Life Science
BAO, Sheng
Life Science
LE, Cong Truc
Life Science
LE, Minh Ngoc
Life Science
TRINH, Tam Anh
Life Science

Master of Philosophy

LE, Nguyen Bao Tran
Life Science

Graduated RPGs

Doctor of Philosophy

NGUYEN, Trung Duc
Life Science( Completed in 2023 )

Master of Philosophy

NGO, Minh Khoa
Life Science( Completed in 2024 )
LE, Cong Truc
Life Science( Completed in 2021 )
LE, Minh Ngoc
Life Science( Completed in 2021 )
LE, Thi Nhu Y
Life Science( Completed in 2021 )

Projects

From January 2022 to December 2024

All Projects 4

No Projects.
Molecular mechanism of mutations in Microprocessor causing Wilms tumors

引起Wilms腫瘤的miRNA加工復合體突變的分子機制 Leading

National Natural Science Foundation of China
Project Team (HKUST)
NGUYEN Tuan Anh (Lead)
2024 -
Molecular mechanism of RNA-binding Triads in controlling the shRNA/pre-miRNA cleavage by DICER-TRBP

DICER-TRBP控制的shRNA/pre-miRNA剪切過程中RNA結合蛋白三聯體的分子機制 Leading

RGC - General Research Fund
Project Team (HKUST)
NGUYEN Tuan Anh (Lead)
2023 -
The non-canonical pri-miRNA processing mechanism of human Microprocessor

人源miRNA加工復合體的非經典RNA加工機制 Leading

RGC - General Research Fund
Project Team (HKUST)
NGUYEN Tuan Anh (Lead)
2022 -
Roles of human DDX and DHX helicases in RNA metabolism and miRNA biogenesis Leading

Croucher Foundation
Project Team (HKUST)
NGUYEN Tuan Anh (Lead)
2019 -

Research Interest

Publications

2024 3

2023 6

2022 2

2021 2

2020 4

2019 1

2018 2

2016 1

2015 3

2014 1

2012 3

2011 2

2010 1

2009 2

Article 3

Article 4

Book chapter 2

Article 2

Article 2

Article 4

Article 1

Article 2

Article 1

Article 3

Article 1

Article 3

Article 1

Book chapter 1

Article 1

Article 2

2018 2

2016 1

2015 3

2014 1

2012 3

2011 2

2010 1

2009 2

Teaching Assignment

Research Postgraduate (RPG) Supervision

From January 2021 to December 2024 (As of 21 November 2024)

Current RPGs

Graduated RPGs

Projects

From January 2022 to December 2024

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