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Nancy Yuk-Yu IP
葉玉如

PhD in Pharmacology
Harvard University, 1983

President

The Morningside Professor of Life Science

Chair Professor
Division of Life Science

Director of State Key Laboratory of Molecular Neuroscience

  • (852) 2358 6101
  • boip@ust.hk
  • Room 6349
  • Personal Web

ORCID
0000-0002-2763-8907
Scopus ID
7005756760
Research Interest Publications Projects Teaching Assignment RPG Supervision Space used

Research Interest


  • Neuroscience

Publications


All Years 621 2023 3 2022 12 2021 19 2020 7 2019 14 2018 9 2017 557

2023 3

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Communications Medicine, v. 3, April 2023, article number 49
Alzheimer’s Disease Neuroimaging Initiative; Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Lv, Ge; Zhang, Huan; Chen, Jiahang; Ye, Tao; Chen, Yuewen; Zhang, Yulin; Ma, Shuangshuang; Lo, Ronnie M.N.; Tong, Pui Sze; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Guo, Qihao; Mok, Kin Ying Boniface; Shoai, Maryam; Hardy, John; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Receptor-ligand interaction controls microglial chemotaxis and amelioration of Alzheimer's disease pathology

Journal of Neurochemistry, v. 166, (6), September 2023, p. 891-903
Lau, Shun Fat; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

The role of genetic risk factors of Alzheimer's disease in synaptic dysfunction

Seminars in Cell and Developmental Biology, v. 139, April 2023, p. 3-12
Fu, Wing Yu; Ip, Nancy Yuk-Yu
Article
2022 12

AAV Capsid Variants with Brain-Wide Transgene Expression and Decreased Liver Targeting after Intravenous Delivery in Mouse and marmoset

Nature Neuroscience, v. 25, (1), January 2022, p. 106-115
Goertsen, David; Flytzanis, Nicholas C.; Goeden, Nick; Chuapoco, Miguel; Cummins, Alexander; Chen, Yijing; Fan, Yingying; Zhang, Qiangge; Sharma, Jitendra; Duan, Yangyang; Wang, Liping; Feng, Guoping; Chen, Yu; Ip, Nancy Yuk-Yu; Pickel, James; Gradinaru, Viviana
Article

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Nature Aging, v. 2, (7), July 2022, p. 616-634
Jiang, Yuanbing; Zhou, Xiaopu; Wong, Hiu Yi; Ouyang, Li; Ip, Fanny Chui Fun; Chau, Man Ni; Lau, Shun Fat; Wu, Wei; Wong, Yew Kit Daniel; Seo, Heukjin; Fu, Wing Yu; Lai, Chit Hang; Chen, Yuewen; Chen, Yu; Tong, Pui Sze; Alzheimer’s Disease Neuroimaging Initiative; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Mok, Kin Ying Boniface; Shoai, Maryam; Lehallier, Benoit; Losada, Patricia Moran; O'Brien, Eleanor; Porter, Tenielle; Laws, Simon M.; Hardy, John; Wyss-Coray, Tony; Masters, Colin L.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Association of SPI1 haplotypes with altered SPI1 gene expression and Alzheimer’s disease risk

Journal of Alzheimer's Disease, v. 86, (4), April 2022, p. 1861-1873
Cao, Han; Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Chen, Yuewen; Lai, Chit Hang; Lo, Ming Nok; Tong, Pui Sze; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Alzheimer’s Disease Neuroimaging Initiative; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Nature Biomedical Engineering, v. 6, (2), February 2022, p. 168-180
Duan, Yangyang; Ye, Tao; Qu, Zhe; Chen, Yuewen; Miranda, Abigail Orquiza; Zhou, Xiaopu; Lok, Ka Chun; Chen, Yu; Fu, Kit Yu; Gradinaru, Viviana; Ip, Nancy Yuk-yu
Article

Deep tissue multi-photon imaging using adaptive optics with direct focus sensing and shaping

Nature Biotechnology, v. 40, (11), November 2022, p. 1663-1671
Qin, Zhongya; She, Zhentao; Chen, Congping; Wu, Wanjie; Lau, Ka Yan Jackie; Ip, Nancy Yuk-yu; Qu, Jianan
Article

Demographics and Medication Use of Patients with Late-Onset Alzheimer’s Disease in Hong Kong

Journal of Alzheimer's Disease, v. 87, (3), May 2022, p. 1205-1213
Wong, Hiu Yi; Zhong, Huan; Zhou, Xiaopu; Chan, Phillip Y.C.; Kwok, Timothy C.Y.; Mok, Kin; Hardy, John; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms

The FEBS Journal, v. 289, (8), April 2022, p. 2202-2218
Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging

Alzheimer's & Dementia, v. 18, (1), January 2022, p. 88-102
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Nicole C. H.; Cheung, Kit; Lo, Ronnie M. N.; Tong, Pui Sze; Wong, Bonnie W. Y.; Chan, Andrew L. T.; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Multi-Omics-Based Autophagy-Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology

Advanced Science, 13 June 2022, article number 2201212
Park, Jong-Chan; Barahona-Torres, Natalia; Jang, So-Young; Mok, KinY.; Kim, HaengJun; Han, Sun-Ho; Cho, Kwang-Hyun; Zhou, Xiaopu; Fu, Amy K.Y.; Ip, Nancy Yuk-yu; Seo, Jieun; Choi, Murim; Jeong, Hyobin; Hwang, Daehee; Lee, Dong Young; Byun, Min Soo; Yi, Dahyun; Han, Jong Won; Mook-Jung, Inhee; Hardy, John
Article

An IL1RL1 genetic variant lowers soluble ST2 levels and attenuates the impact of APOE-ε4 in Alzheimer's disease


Jiang, Yuanbing; Zhou, Xiaopu; Wong, Hiu Yi; Ouyang, Li; Ip, Fanny Chui Fun; Chau, Man Ni; Lau, Shun Fat; Wu, Wei; Seo, Heukjin; Fu, Wing Yu; Lai, Chit Hang; Chen, Yuewen; Chen, Yu; Tong, Pui Sze; Alzheimer's Disease Neuroimaging Initiative; Mok, Vincent C.T.; Kwok, Timothy C. Y.; Lehallier, Benoit; Losada, Patricia Morán; O'Brien, Eleanor; Porter, Tenielle; Laws, Simon M.; Wyss-Coray, Tony; Masters, Colin L.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

How Long is Enough? Exploring the Optimal Intervals of Long-Range Clinical Note Language Modeling

Proceedings of the 13th International Workshop on Health Text Mining and Information Analysis (LOUHI) / Association for Computational Linguistics. Stroudsburg, USA : Association for Computational Linguistics, 2022, p. 160-172
Cahyawijaya, Samuel; Wilie, Bryan; Lovenia, Holy; Zhong, Mingqian; Zhong, Huan; Ip, Nancy Yuk-yu; Fung, Pascale
Conference paper

SNP2Vec: Scalable Self-Supervised Pre-Training for Genome-Wide Association Study

Proceedings of the 21st Workshop on Biomedical Language Processing / edited by Dina Demner-Fushman, Kevin Bretonnel Cohen, Sophia Ananiadou, Junichi Tsujii. Stroudsburg, USA : Association for Computational Linguistics, 2022, p. 140-154
Cahyawijaya, Samuel; Yu, Tiezheng; Liu, Zihan; Mak, Tiffany T.W.; Zhou, Xiaopu; Ip, Nancy Yuk-yu; Fung, Pascale
Conference paper
2021 19

A near-infrared AIE fluorescent probe for myelin imaging: From sciatic nerve to the optically cleared brain tissue in 3D

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (45), 9 November 2021, article number e2106143118
Wu, Ming-Yu; Wong, Alex Y. H.; Leung, Jong-Kai; Kam, Chuen; Wu, Kenneth Lap-Kei; Chan, Ying-Shing; Liu, Kai; Ip, Nancy Yuk-yu; Chen, Sijie
Article

A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice

European Journal of Medicinal Chemistry, v. 226, December 2021, article number 113827
Ip, Fanny Chui Fun; Fu, Guangmiao; Yang, Fengzhi; Kang, Fangyuan; Sun, Peiran; Ling, Choi Ying; Cheung, Kit; Xie, Fangzhou; Hu, Yueqing; Fu, Lei; Ip, Nancy Yuk-yu
Article

APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention

Current Opinion in Neurobiology, v. 69, August 2021, p. 58-67
Zhou, Xiaopu; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (1), January 2021, article number e2020810118
Wang, Ye; Fu, Wing Yu; Cheung, Kit; Hung, Kwok Wang; Chen, Congping; Geng, Hongyan; Yung, Wing Ho; Qu, Jianan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Blood transcriptome analysis for Alzheimer' disease in Hong Kong Chinese population

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, v. 17, (S3), December 2021, article number e056643
Zhong, Huan; Zhou, Xiaopu; Jiang, Yuanbing; Chen, Yu; Lai, N.C.H.; Tong, Pui Sze; Lo, Ronnie M.N.; Kwok, Timonthy C.Y.; Mok, Vincent C.T.; Ip, Fanny Chui Fun; Mok, Kin Ying Boniface; Hardy, John; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Cellular and Molecular Life Sciences, 13 April 2021
Lau, Shun Fat; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Deep learning for polygenic score analysis for Alzheimer's disease risk prediction in the Chinese population

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, v. 17, (S3), December 2021, article number e056625
Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Yuewen; Chen, Jiahang; Zhang, Yulin; Ma, Shuangshuang; Lai, Nicole Chit Hang; Lo, Ronnie M.N.; Cheung, Kit; Tong, Pui Sze; Mok, Kin Ying Boniface; Hardy, John; Guo, Qihao; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Communications Biology, v. 4, (1), February 2021, article number 195
Ye, Tao; Duan, Yangyang; Tsang, Hayley Wing Sum; Xu, He; Chen, Yuewen; Cao, Han; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

GSAP Regulates Lipid Homeostasis and Mitochondrial Function Associated with Alzheimer's Disease

Journal of Experimental Medicine, v. 218, (8), June 2021, article number e20202446
Xu, Peng; Chang, Jerry C.; Zhou, Xiaopu; Wang, Wei; Bamkole, Michael; Wong, Eitan; Bettayeb, Karima; Jiang, Lu-Lin; Huang, Timothy; Luo, Wenjie; Xu, Huaxi; Nairn, Angus C.; Flajolet, Marc; Ip, Nancy Yuk-yu; Li, Yue-Ming; Greengard, Paul
Article

High-resolution two-photon transcranial imaging of brain using direct wavefront sensing

Photonics Research, v. 9, (6), June 2021, p. 1144-1156
Chen, Congping; Qin, Zhongya; He, Sicong; Liu, Shaojun; Lau, Shun Fat; Wu, Wanjie; Zhu, Dan; Ip, Nancy Yuk-yu; Qu, Jianan
Article

IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry

DNA and Cell Biology, v. 40, (9), September 2021, p. 1125-1130
Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

Scientific Reports, v. 11, (1), February 2021, article number 4359
Lau, Ka Yan Jackie; Tian, Min; Shen, Yang; Lau, Shun Fat; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Polygenic Score Models For Alzheimer’s Disease: From Research To Clinical Applications

Frontiers in Neuroscience, v. 15, 29 March 2021, article number 650220
Zhou, Xiaopu; Li, Yolanda Yuen Tung; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model

STAR Protocols, v. 2, (1), March 2021, article number 100265
Lau, Shun Fat; Wu, Wei; Seo, Heukjin; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Retinal Dysfunction In Alzheimer’s Disease And Implications For Biomarkers

Biomolecules, v. 11, (8), August 2021, article number 1215
Liao, Chunyan; Xu, Jinying; Chen, Yu; Ip, Yuk-yu, Nancy
Article

Rhynchophylline Administration Ameliorates Amyloid-beta Pathology and Inflammation in an Alzheimer's Disease Transgenic Mouse Model

ACS Chemical Neuroscience, v. 12, (22), November 2021, p. 4249-4256
Fu, Wing Yu; Hung, Kwok Wang; Lau, Shun Fat; Butt, Busma; Yuen, Wai Hin; Fu, Guangmiao; Chan, Chi Wai; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

A high-performance biomarker panel for Alzheimer's disease screening and staging identified by large-scale plasma proteomic profiling


Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Chit Hang; Cheung, Kit; Lo, Ming Nok; Tong, Pui Sze; Wong, Wing Yan; Chan, Andrew L.T.; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

A high-performance biomarker panel for Alzheimer's disease screening and staging identified by large-scale plasma proteomic profiling

The Journal of the Alzheimer’s Association, v. 17, (S5), December 2021, article number e056099, Supplement: Biomarkers – Part 2
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Chit Hang; Cheung, Kit; Lo, Ming Nok; Tong, Pui Sze; Wong, Wing Yan; Chan, Andrew L.T.; Mok, Vincent C.T.; Kwok, Timonthy C.Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

Deep learning for polygenic score analysis for Alzheimer’s disease risk prediction in the Chinese population


Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Yuewen; Chen, Jiahang; Zhang, Yulin; Ma, Shuangshuang; Lai, Chit Hang; Lo, Ming Nok; Cheung, Kit; Tong, Pui Sze; Mok, Kin Ying Boniface; Hardy, John; Guo, Qihao; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper
2020 7

A Pentacyclic Triterpene from Ligustrum lucidum Targets γ-Secretase

ACS Chemical Neuroscience, v.11, (18), 16 September 2020, p. 2827-2835
Luo, Wenjie; Ip, Fanny Chui Fun; Fu, Guangmiao; Cheung, Kit; Tian, Yuan; Hu, Yueqing; Sinha, Anjana; Cheng, Elaine Y.L.; Wu, Xianzhong; Bustos, Victor; Greengard, Paul; Li, Yue-Ming; Sinha, Subhash C.; Ip, Nancy Yuk-yu
Article

Adaptive optics two-photon endomicroscopy enables deep-brain imaging at synaptic resolution over large volumes

Science Advances, v. 6, (40), 30 September 2020, article number eabc6521
Qin, Zhongya; Chen, Congping; He, Sicong; Wang, Ye; Tam, Kam Fai; Ip, Nancy Yuk-Yu; Qu, Jianan
Article

Genetic and polygenic risk score analysis for Alzheimer’s disease in the Chinese population

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, v. 12, (1), August 2020, article number e12074
Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Lai, Nicole C.H.; Li, Yuen Tung; Jiang, Yuanbing; Zhong, Huan; Chen, Yuewen; Zhang, Yulin; Ma, Shuangshuang; Lo, Ronie M.N.; Cheung, Kit; Tong, Pui Sze; Ko, Ho; Shoai, Maryam; Mok, Kin Ying Boniface; Hardy, John; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease

Cell Reports, v. 31, (3), April 2020, article number 107530
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

p39-associated Cdk5 activity regulates dendritic morphogenesis

Scientific Reports, v. 10, (1), December 2020, article number 18746
Ouyang, Li; Chen, Yu; Wang, Ye; Chen, Yuewen; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-yu
Article

Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America, v. 117, (41), 13 October 2020, p. 25800-25809
Lau, Shun Fat; Cao, Han; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Adaptive optics two-photon microendoscopy for high-resolution and deep-brain imaging in vivo

Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 11226, February 2020, article number 1122606
Chen, Congping; Qin, Zhongya; He, Sicong; Wu, Wanjie; Wang, Ye; Tam, Kam Fai; Ip, Nancy Yuk-Yu; Qu, Jianan
Conference paper
2019 14

Asymmetric Total Syntheses of Rhynchophylline and Isorhynchophylline

Journal of Organic Chemistry, v. 84, (17), August, 2019, p. 11359-11365
Zhang, Zhihong; Zhang, Wei; Kang, Fangyuan; Ip, Chui Fun Fanny; Ip, Nancy Yuk-yu; Tong, Rongbiao
Article

Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer's Disease

ACS Chemical Neuroscience, v. 10, (9), August 2019, p. 3986-3996
Chen, Yuewen; Xu, Jinying; Zhou, Xiaopu; Liu, Saijuan; Zhang, Yulin; Ma, Shuangshuang; Fu, Kit Yu; Ip, Nancy Yuk-yu; Chen, Yu
Article

Increased Axin expression enhances adult hippocampal neurogenesis and exerts an antidepressant effect

Scientific Reports, v. 9, February 2019, article number 1190, p. 1-10
Chen, Weiwei; Fu, Wing Yu; Su, Yiting; Fang, Weiqun; Fu, Amy K. Y.; Ip, Nancy Yuk-yu
Article

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Nature Communications, v. 10, (1), December 2019, article number 3310
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Kwok, Timothy C. Y.; Mok, Vincent C. T.; Guo, Qihao; Ip, Chui Fun Fanny; Chen, Yuewen; Mullapudi, Nandita; Giusti-Rodríguez, Paola; Sullivan, Patrick F.; Hardy,John; Fu, Kit Yu; Li, Yun; Ip, Nancy Yuk-yu
Article

Synaptic Dysfunction in Alzheimer's Disease: Mechanisms and Therapeutic Strategies

Pharmacology and Therapeutics, v. 195, March 2019, p. 186-198
Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Targeting Neuroinflammation as a Therapeutic Strategy for Alzheimer's Disease: Mechanisms, Drug Candidates, and New Opportunities

ACS Chemical Neuroscience, v. 10, (2), February 2019, p. 872-879
Fu, Wing-Yu; Wang, Xiujiao; Ip, Nancy Yuk-yu
Article

α2-chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis

Proceedings of the National Academy of Sciences of the United States of America, v. 116, (27), June 2019, p. 13651-13660
Su, Yiting; Lau, Shun Fat; Ip, P.K. Jacque; Cheung, Kit; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Adaptive Optics Two-photon Microscopy for in Vivo Imaging of Cortex and Hippocampus in Mouse Brain

Proceedings of SPIE - Neural Imaging and Sensing, v. 10865, 2019, article number 108650M
Chen, Congping; Qin, Zhongya; He, Sicong; Lui, Yan Lik Caleb; Ip, Nancy Yuk-Yu; Qu, Jianan
Conference paper

Deregulation of IL-33/ST2 signaling in Alzheimer’s disease


Jiang, Yuanbing; Zhou, Xiaopu; Wang, Ye; Lai, N.C.H.; Tong, Pui Sze; Mok, V.C.T.; Kwok, T.C.Y.; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

IL-33/ST2 signaling promotes excitatory synapse formation in the hippocampus


Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

IL-33-dependent transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease


Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk


Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Kwok, T.C.Y.; Mok, V.C.T.; Guo, Q.; Ip, Fanny C.F.; Chen, Y.; Mullapudi, Nandita; Hardy, J.; Fu, Kit Yu; Li, Y.; Ip, Nancy Yuk-yu
Conference paper

Role of IL-33/ST2 signaling in homeostatic synaptic plasticity in the hippocampus


Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Whole-genome sequencing for Alzheimer’s disease risk in the Chinese population


Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Mok, V.C.T.; Guo, Q.; Ip, Fanny C.F.; Chen, Y.; Hardy, J.; Li, Y.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper
2018 9

Avian influenza A H7N9 virus infects human astrocytes and neuronal cells and induces inflammatory immune responses.

Journal of NeuroVirology, v. 24, (6), December 2018, p. 752-760
Ng, Yu Pong; Yip, TF; Malik peiris, JS; Ip, Nancy Yuk-yu; Lee, SMY
Article

Dopamine receptors mediate strategy abandoning via modulation of a specific prelimbic cortex-nucleus accumbens pathway in mice

Proceedings of the National Academy of Sciences of the United States of America, v. 115, (21), May 2018, p. E4890-E4899
Cui, Qiaoling; Li, Qian; Geng, Hongyan; Chen, Lei; Ip, Nancy Yuk-yu; Ke, Ya; Yung, Wing-Ho
Article

Identification of Genetic Risk Factors in The Chinese Population Implicates a Role of the Immune System in Alzheimer’s Disease Pathogenesis

Proceedings of the National Academy of Sciences of the United States of America, v. 115, (8), February 2018, p. 1697-1706
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Zhao, Qianhua; Chen, Keliang; Chen, Yuewen; Hardy, John; Li, Yun; Fu, Kit Yu; Guo, Qihao; Ip, Nancy Yuk-yu
Article

Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs

Scientific Reports, v. 8, (1), May 2018, article number 7377, p. 1-7
Gu, shuo; Fu, Wing Yu; Fu, Kit Yu; Tong, Pui See; Ip, Fanny Chui-Fun; Huang, Xuhui; Ip, Nancy Yuk-Yu
Article

In Vivo Near-Infrared Two-Photon Imaging of Amyloid Plaques in Deep Brain of Alzheimer’s Disease Mouse Model

ACS Chemical Neuroscience, v. 9, (12), December 2018, p. 3128-3136
Chen, Congping; Liang, Zhuoyi; Zhou, Biao; Li, Xuesong; Lui, Yan Lik Caleb; Ip, Nancy Yuk-yu; Qu, Jianan
Article

Methods to study the signal transduction of the surface receptor tyrosine kinase TrkB in neurons

Methods in Molecular Biology, v. 1722, 2018, p. 211-222
Lai, Kwok On; Ip, Nancy Yuk-yu
Article

Two Pairs of Unusual Melibiose and Raffinose Esters From Scrophularia Ningpoensis

Journal of Asian Natural Products Research, v. 20, (3), March 2018, p. 255-262
Zhang, Jun; Liang, Yang; Ip, Fanny C. F.; Ip, Nancy Yuk-yu; Liu, Ting-Ting; Zhong, Ba-Lian; Xu, Shi-Hai
Article

Deep brain two-photon NIR fluorescence imaging for study of Alzheimer’s disease

Proceedings of SPIE: Neural Imaging and Sensing 2018, v. 10481, May 2018, article number 104810A, Progress in Biomedical Optics and Imaging
Chen, Congping; Liang, Zhuoyi; Zhou, Biao; Ip, Nancy Yuk-Yu; Qu, Jianan
Conference paper

IL-33/ST2 signaling enhances the formation of excitatory synapses in the hippocampus


Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper
2017 8

A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes

Developmental Cell, v. 41, (4), May 2017, p. 382-391.e5
An, Yitai; Wang, Gang; Diao, Yarui; Long, Yanyang; Fu, Xinrong; Weng, Mingxi; Zhou, Liang; Sun, Kun; Cheung, Tom H.; Ip, Nancy Yuk-yu; Sun, Hao; Wang, Huating; Wu, Zhenguo
Article

A New Iridoid Glycoside and a New Cinnamoyl Glycoside from Scrophularia Ningpoensis Hemsl

Natural Product Research, v. 31, (20), March 2017, p. 2361-2368
Zhang, Jun; Ip, Fanny C. F.; Liang, Yan; Ip, Nancy Yuk-yu; Zhong, Ba-Lian; Lai, Chun-Wang; Xu, Shi-Hai
Article

Anemoside A3 Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating T Helper 17 Cell Response

PLoS ONE, v. 12, (7), July 2017, article number e0182069
Ip, Fanny; Ng, Yupong; Or, Terry Cho Tsun; Sun, Peiran; Fu, Guangmiao; Li, Jessica Y.H.; Ye, Wencai; Cheung, Tom H.; Ip, Nancy Y.Y.
Article

Cdk5-Dependent Phosphorylation of Liprinα1 Mediates Neuronal Activity-Dependent Synapse Development

Proceedings of the National Academy of Sciences of the United States of America, v. 114, (33), August 2017, p. E6992-E7001
Huang, Huiqian; Lin, Xiaochen; Liang, Zhuoyi; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Homeostatic Scaling of AMPA Receptors by Semaphorin

Neuron, v. 96, (5), 6 December 2017, p. 955-958
Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Regulation of postsynaptic signaling in structural synaptic plasticity

Current Opinion in Neurobiology, v. 45, Aug 2017, p. 148-155
Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Activation of the melanocortin 4 receptor signaling pathway ameliorates Alzheimer’s disease-like pathology


Tian, Min; Shen, Yang; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

IL-33 enhances the development of hippocampal excitatory synapses


Hung, Kwok Wang; Wang, Ye; Chuang, Ching Yi; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper
2016 29

China Brain Project: Basic Neuroscience, Brain Diseases, and Brain-Inspired Computing

Neuron, v. 92, (3), November 2016, p. 591-596
Poo, Mu-ming; Du, Jiu-lin; Ip, Nancy Y. Y.; Xiong, Zhi-Qi; Xu, Bo; Tan, Tieniu
Article

Design and Synthesis of Dimeric Securinine Analogs with Neuritogenic Activities

ACS Chemical Neuroscience, v. 7, (10), October 2016, p. 1442-1451
Tang, Genyun; Liu, Xin; Ma, Nan; Huang, Xiaojie; Wu, Zhen-Long; Zhang, Wen; Wang, Ying; Zhao, Bing-Xin; Wang, Zhen-Ya; Ip, Fanny C. F.; Ip, Nancy Y. Y.; Ye, Wen-Cai; Shi, Lei; Chen, Wei-Min
Article

Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition)

Autophagy, v. 12, (1), January 2016, p. 1-222
Ip, Nancy Yuk-Yu
Article

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline

Proceedings of the National Academy of Sciences of the United States of America, v. 113, (19), May 2016, p. 2705-2713
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu
Article

Multicolor 4D fluorescence microscopy using ultrathin bessel light sheets

Scientific Reports, v. 6, May 2016, article number 26159
Zhao, Teng; Lau, Sze Cheung; Wang, Ying; Su, Yumian; Wang, Hao; Cheng, Aifang; Herrup, Karl; Ip, Nancy Y.; Du, Shengwang; Loy, M.M.T.
Article

Neuroprotective Effect of a Novel Chinese Herbal Decoction on Cultured Neurons and Cerebral Ischemic Rats

BMC Complementary and Alternative Medicine, v. 16, (1), November 2016, article number 437
Ip, Fanny Chui-Fun; Zhao, Yuming; Chan, Kim Wan; Cheng, Elaine Yee Ling; Tong, Estella Pui Sze; Chandrashekar, Oormila; Fu, Guangmiao; Zhao, Zhong-Zhen; Ip, Nancy Yuk-Yu
Article

New Lignans with Neuroprotective Activity from Adelostemma Gracillimum

Phytochemistry Letters, v. 16, June 2016, p. 1-7
Zhang, Jun; Guo, Shengjun; Chan, Kim Wan; Tong, Pui Sze; Fu, Guangmiao; Mu, Quanzhang; Ip, Fanny C.F.; Ip, Nancy Y.Y.
Article

STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration

Cell Reports, v. 16, (8), 23 August 2016, p. 2102-2115
Zhu, Han; Xiao, Fang; Wang, Gang; Wei, Xiuqing; Jiang, Lei; Chen, Yan; Zhu, Lin; Wang, Haixia; Diao, Yarui; Wang, Huating; Ip, Nancy Y Y; Cheung, Tom H.; Wu, Zhenguo
Article

Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer’s Disease Model

Cell Reports, v. 17, (7), November 2016, p. 1819-1831
Shen, Yang; Tian, Min; Zheng, Yuqiong; Gong, Fei; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

The Pseudokinase CaMKv is Required for the Activity-dependent Maintenance of Dendritic Spines

Nature Communications, v. 7, October 2016, article number 13282
Liang, Zhuoyi; Zhan, Yi; Shen, Yang; Wong, Catherine C.L.; Yates, John R.R.; Plattner, Florian; Lai, Kwok On; Ip, Nancy Y.Y.
Article

Worldwide initiatives to advance brain research

Nature Neuroscience, v. 19, (9), August 2016, p. 1118-1122
Grillner, Sten; Ip, Nancy Y Y; Koch, Christof; Koroshetz, Walter; Okano, Hideyuki; Polachek, Miri; Poo, Mu-ming; Sejnowski, Terrence Joseph
Article

Cdk5 Activity is Required for EphB-mediated Synaptogenesis


Chen, Yu; Wong, Yung Hou; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-mediated Phosphorylation of Liprinα1 is Critical for Synaptic Plasticity


Huang, Huiqian; Lin, Xiaochen; Liang, Zhuoyi; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

Characterization of Pathogenic Mutations and Cellular Phenotypes of Alzheimer’s Disease using Human Induced Pluripotent Stem Cells


Ip, Nancy Yuk-Yu; Fu, Kit Yu; Tong, Pui Sze; Tu, X.; Ye, Tao
Conference paper

Coronin 2B is an Important Regulator of Neuronal Polarization


Chen, Yu; Chen, Y.; Zhang, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Elucidation of the Functional Roles of Rho GTPase-activating Proteins in Adult Neurogenesis


Su, Yiting; Ip, Pak Kan; Min, Lan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Elucidation of the Functional Roles of Rho GTPase-Activating Proteins in Adult Neurogenesis


Su, Yiting; Ip, Nancy Yuk-Yu; Min, L.; Ip, Pak Kan; Fu, Kit Yu
Conference paper

Fine Mapping of the APOE Locus by Low-pass Whole-genome Sequencing in Chinese Alzheimer’s Disease Patients


Zhou, Xiaopu; Chen, Yu; Zhao, Q.; Chu, M.K.M.; Kwok, C.T.; Mok, K.Y.; Zhang, B.; Fu, Kit Yu; Li, Y.; Guo, Q.; Ip, Nancy Yuk-yu
Conference paper

Functional roles of Rho GTPase-activating proteins in adult neurogenesis


Su, Yiting; Ip, Nancy Yuk-Yu; Ip, Pak Kan; Min, L.; Fu, Kit Yu
Conference paper

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline


Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, I.C.W.; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu
Conference paper

IL-33 ameliorates cognitive deficits and amyloid pathology in an Alzheimer’s disease-like mouse model


Fu, Kit Yu; Hung, Kwok Wang; Yuen, M.Y.F.; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Cheung, Tom; Zhang, B; Fu, Wing Yu; Liew, F.Y.; Ip, Nancy Yuk-yu
Conference paper

IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model


Zhou, Xiaopu; Ip, Nancy Yuk-yu; Cheung, Tom; Liew, F.Y.; Chan, I.C.W.; Mak, D.S.Y.; Yuen, M.Y.F.; Hung, Kwok Wang; Fu, Kit Yu; Fu, Wing Yu
Conference paper

IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model


Ip, Nancy Yuk-Yu
Conference paper

IL-33 Modulates the Inflammatory Response in the Brains of Alzheimer’s disease mouse model


Fu, Wing Yu; Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Liew, F.Y.; Cheung, Tom H.; Ip, Nancy Yuk-yu
Conference paper

MC4R Activation Alleviates Amyloid-Beta–Induced Synaptic Dysfunction


Gong, Fei; Shen, Yang; Tian, Min; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin 4 Receptor Activation Ameliorates Synaptic Plasticity Impairment in a Mouse Model of Alzheimer’s Disease


Ip, Nancy Yuk-Yu; Lai, Kwok On; Plattner, F.; Yates, III; John, R.; Wong, C.C.L.; Shen, Yang; Zhan, Y.; Liang, Zhuoyi
Conference paper

The Pseudokinase CaMKv Is Required for the Activity-Dependent Maintenance of Dendritic Spines


Liang, Zhuoyi; Zhan, Yi; Shen, Yang; Wong, Catherine C.L.; Yates, John R.R.; Plattner, Florian; Lai, Kwok On; Ip, Nancy Yuk-Yu; John, R.
Conference paper

The Pseudokinase CaMKv Is Required For The Activity-Dependent Maintenance of Dendritic Spines


Liang, Zhuoyi; Zhan, Yi; Shen, Yang; Wong, Catherine C.L.; Yates, John R.R.; Plattner, Florian; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Understanding the Melanocortin Microcircuit in the Mouse Hippocampus


Tian, Min; Ip, Nancy Yuk-Yu; Fu, Kit Yu; Zheng, Y.Q.; Shen, Yang
Conference paper
2015 30

Anemoside A3 enhances cognition through the regulation of synaptic function and neuroprotection

Neuropsychopharmacology, v. 40, (8), July 2015, p. 1877-1887
Ip, Fanny Chun Fun; Fu, Wingyu; Cheng, Elaineyl; Tong, Estellaps; Lok, Kachun; Liang, Yan; Ye, Wencai; Ip, Nancy Yuk Yu
Article

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling

PLoS ONE, v. 10, (7), July 2015, article number e0133115
Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Chen, Yuewen; Zhou, Xiaopu; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Cdk5 regulates activity-dependent gene expression and dendrite development

Journal of Neuroscience, v. 35, (45), November 2015, p. 15127-15134
Liang, Zhuoyi; Ye, Tao; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk Yu
Article

Cdk5: A Key Player at Neuronal Synapse with Diverse Functions

Mini-Reviews in Medicinal Chemistry, v. 15, (5), 2015, p. 390-395
Lai, Kwok-On; Ip, Nancy Y.Y.
Article

Challenges and opportunities in bioscience for women in China

Asian Biotechnology and Development Review, v. 17, (1), 2015, p. 7-14
Ip, Nancy Yuk-yu
Article

ChemInform Abstract: Highly trans-Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ-Deoxygenation and Heck—Matsuda Reaction: Asymmetric Total Synthesis of (-)-Musellarins A—C (I) and Their Analogues

ChemInform, v. 46, (49), December 2015
Li, Zhilong; Ip, Fanny C.F.; Ip, Nancy Y.Y.; Tong, Rongbiao
Article

Cyclin-dependent kinase 5 (Cdk5)-dependent phosphorylation of p70 ribosomal S6 kinase 1 (S6K) is required for dendritic spine morphogenesis

Journal of Biological Chemistry, v. 290, (23), June 2015, p. 14637-14646
Lai, Kwok-On; Liang, Zhuoyi; Fei, Erkang; Huang, Huiqian; Ip, Nancy Yuk Yu
Article

Emerging roles of axin in cerebral cortical development

Frontiers in Cellular Neuroscience, v. 9, June 2015, article number 217, p. 1-8
Ye, Tao; Fu, Kit Yu; Ip, Nancy Y.Y.
Article

Highly trans-Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ-Deoxygenation and Heck-Matsuda Reaction: Asymmetric Total Synthesis of (-)-Musellarins A-C and Their Analogues

Chemistry - A European Journal, v. 21, (31), 2015, p. 11152-11157
Li, Zhilong; Ip, Fanny Chui Fun; Ip, Nancy Yuk-Yu; Tong, Rongbiao
Article

Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons

Neurobiology of Disease, v. 73, January 2015, p. 366-376
Li, Songshan; He, Qinghai; Wang, Hao; Tang, Xuming; Ho, Kam Wing; Gao, Xin; Zhang, Qian; Shen, Yang; Cheung, Annie; Wong, Francis; Wong, Yung Hou; Ip, Nancy Yuk-yu; Jiang, Liwen; Yung, Wing Ho; Liu, Kai
Article

Neddylation is needed for synapse maturation

Nature Neuroscience, v. 18, (2), February 2015, p. 164-166
Fu, Kit Yu; Ip, Nancy Y.Y.
Article

Neurodegenerative Diseases: What Is to Be Done?

Translational Neuroscience: Toward New Therapies, v. 7, 2015, p. 93-113
Holtzman, D.M.; Nikolich, K.; Pangalos, M.N.; Broich, K.; Ip, Nancy Y.Y.; Koo, E.H.; Koroshetz, W.J.; Masliah, E.; Mucke, L.; Nicotera, P.; Schnaars, M.; Spillantini, M.G.
Article

Ningpoensines A-C: Unusual zwitterionic alkaloids from Scrophularia ningpoensis

Tetrahedron Letters, v. 56, (40), September 2015, p. 5453-5456
Zhang, Jun; Ip, Fanny; Tong, Estellaps; Chan, Kimwan; Li, Liangchun; Ng, Yupong; Ip, Nancy Y.
Article

NRC-interacting factor directs neurite outgrowth in an activity-dependent manner

Neuroscience, v. 289, March 2015, p. 207-213
Zhao, Xiao Su; Fu, Wing Yu; Hung, Kwok Wang; Chien, Winnie W.Y.; Li, Zhongrui; Fu, Kit Yu; Ip, Nancy Y.Y.
Article

Plant alkaloids as drug leads for Alzheimer's disease

Neurochemistry International, v. 89, October 2015, p. 260-270
Ng, Yu Pong; Or, Terry Cho Tsun; Ip, Nancy Yuk-Yu
Article

S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength

Nature Communications, v. 6, October 2015, article number 8665
Zhang, Peng; Fu, Wingyu; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

Activity-Dependent Regulation of Liprinα1 Phosphorylation During Synapse Development


Huang, Huiqian; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Activity-Dependent Regulation of Liprinα1 Phosphorylation During Synapse Development


Huang, Huiqian; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Axin Regulates Dendritic Spine Development via Cdc42 Signaling


Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Zhou, Xiaopu; Fang, Weiqun; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development


Liang, Zhuoyi; Ye, Tao; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

Cdk5-Dependent Phosphorylation of p70 Ribosomal s6 Kinase (S6K) Is Required for Dendritic Spine Morphogenesis


Liang, Zhuoyi; Lai, Kwok On; Fei, Erkang; Huang, Huiqian; Ip, Nancy Yuk-Yu
Conference paper

From Understanding Synaptic Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu
Conference paper

Integrating Basic and Translational Research for Brain Disorders


Ip, Nancy Yuk-Yu
Conference paper

MC4R Signaling Modulation Ameliorates Synaptic Dysfunction in Alzheimer’s Disease Models


Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin 4 Receptor Signaling Modulation Ameliorates Synaptic Dysfunction in Alzheimer's Disease Models


Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Modulation of Melanocortin 4 Receptor Signaling Ameliorates Synaptic Dysfunction in Alzheimer's Disease Models


Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Role of Cdk5 in Activity-Induced Gene Expression and Dendrite Development


Ye, Tao; Liang, Zhuoyi; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

S-Nitrosylation–Dependent Proteasomal Degradation Restricts cdk5 Activity to Regulate Hippocampal Synaptic Strength


Fu, Kit Yu; Zhang, Peng; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Synaptic Plasticity in Health and Disease


Ip, Nancy Yuk-Yu
Conference paper

The EphA4 Inhibitor Rhynchophylline Ameliorates Disease Pathology in a Mouse Model of Alzheimer's Disease


Fu, Wing Yu; Butt, Busma Wai Yin; Hung, Kwok Wang; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper
2014 38

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America, v. 111, (27), July 2014, p. 9959-9964
Fu, Amy Kit Yu; Hung, Kwok Wang; Huang, Huiqian; Gu, Shuo; Shen, Yang; Cheng, Elaine Yee Ling; Ip, Fanny C.F.; Huang, Xuhui; Fu, Wing Yu; Ip, Nancy Yuk Yu
Article

Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition

Journal of Neuroscience, v. 34, (22), May 2014, p. 7425-7436
Tang, Jing; Ip, Pak Kan; Ye, Tao; Ng, Yu Pong; Yung, Wing-Ho; Wu, Zhenguo; Fang, Weiqun; Fu, Kit Yu; Ip, Nancy Yuk Yu
Article

Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex

Nature Communications, v. 5, September 2014, article number 4826
Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton

Journal of Neuroscience, v. 34, (7), 2014, p. 2413-2421
Chen, Yuewen; Ip, Fanny Chui Fun; Shi, Lei; Zhang, Zhe; Tang, Huibin; Ng, Yu Pong; Ye, Wen-Cai; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

CRMP2: Functional roles in neural development and therapeutic potential in neurological diseases

Neuroscientist, v. 20, (6), December 2014, p. 589-598
Ip, Jacque P.K.; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

Cycloastragenol Is a Potent Telomerase Activator in Neuronal Cells: Implications for Depression Management

NeuroSignals, v. 22, (1), May 2014, p. 52-63
Ip, Fanny Chui Fun; Ng, Yu Pong; An, Hui Jin; Dai, Ying; Pang, Hai Hong; Hu, Yue Qing; Chin, Allison C.; Harley, Calvin B.; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Article

Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice

Cell Reports, v. 9, (5), December 2014, p. 1635-1644
Fang, Wei-Qun; Chen, Wei-Wei; Jiang, Liwen; Liu, Kai; Yung, Wing-Ho; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

p35 Regulates the CRM1-Dependent Nucleocytoplasmic Shuttling of Nuclear Hormone Receptor Coregulator-Interacting Factor 1 (NIF-1)

PLoS ONE, v. 9, (10), October 2014, article number e110584
Zhao, Xiao-Su; Fu, Wing-Yu; Chien, Winnie W.Y.; Li, Zhen; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

老年痴呆症的分子机制

生命科学=Chinese Bulletin of Life Sciences, v. 26, (6), June 2014, p. 550-559
沈陽; 陳宇; 傅潔瑜; 葉玉如
Article

老年癡呆癥——現代腦科學和醫學研究面臨的嚴峻挑戰

生命科學=Chinese Bulletin of Life Sciences, v. 26, (1), January 2014, p. 1
葉玉如
Article

Activity-Dependent Regulation of Liprinα1 During Synapse Development


Huang, Huiqian; Lai, Kwok On; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Axin Regulates Synapse Development in the Hippocampus


Liang, Z.; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Blockade of EphA4 Signaling Alleviates Alzheimer's Disease-associated Impairment of Hippocampal Synaptic Plasticity


Hung, Kwok Wang; Fu, Kit Yu; Huang, Huiqian; Gu, Shuo; Cheng, Yee Ling; Ip, Fanny Chui Fun; Fu, Wing-Yu; Ip, Nancy Yuk-Yu
Conference paper

Blockade of EphA4 Signaling Alleviates the Impairment of Hippocampal Synaptic Plasticity Associated With Alzheimer's Disease


Fu, Amy Kit Yu; Hung, Nelson Kwok Wang; Huang, Huiqian; Gu, S.; Shen, Yang; Cheng, Yee Ling; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-mediated Phosphorylation of RapGEF2 Controls Neuronal Migration in the Developing Cortex


Ye, Tao; Ip, Jacque P.K.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Mediated Phosphorylation of RapGEF2 Controls Neuronal Migration in the Developing Cortex


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Mediated Phosphorylation of RapGEF2 Is Required for Neuronal Migration During Cerebral Cortex Development


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Chinese Medicine in Brain Disorders – Traditional Chinese Medicine-Based Drugs for Treating Brain Disorders


Ip, Nancy Yuk-Yu
Conference paper

Cycloastragenol Is a Potent Telomerase Activator in Neuronal Cells: Implications for Depression Management


Ng, Yu Pong; Ip, Fanny Chui Fun; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

From Understanding Neural Plasticity to Drug Discovery for Neurodegenerative Diseases


Ip, Nancy Yuk-Yu
Conference paper

From understanding synaptic plasticity to drug discovery for neurodegenerative diseases

Journal of Neurochemistry, v. 130, August 2014
Ip, Nancy Yuk-Yu
Conference paper

Functional Role of Axin in Synapse Development


Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Functional Role of Axin in Synapse Development


Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Melanocortin-4 Receptor in Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Ada W.Y.; Cheng, Elaine; Tian, Min; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Identification and Characterization of Small Molecule EphA4 Inhibitors as Disease Modifiers for Alzheimer's Disease


Fu, Ada Wing Yu; Hung, Nelson Kwok Wang; Gu, Shuo; Xu, Junyu; Su, A.; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of Novel EphA4 Inhibitors as a Disease-Modifying Treatment for Alzheimer's Disease


Fu, Wing-Yu; Hung, Nelson Kwok Wang; Gu, Shuo; Xu, Jzajing; Su, Audrey; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Ada Wing Yu; Cheng, Yee Ling; Tian, Min; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a PKA-dependent mechanism


Shen, Yang; Fu, Ada W.Y.; Cheng, Yee Ling; Tian, Min; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-dependent Signaling in Synaptic Plasticity and Neurodegenerative Diseases


Ip, Nancy Yuk-Yu
Conference paper

Regulation and Functions of Liprinα1 in Activity-dependent Synapse Development


Huang, H.Q.; Lai, Kwok On; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-nitrosylation of Cdk5 and its Activator p35 in Neuronal Morphogenesis and Synaptic Function


Zhang, Peng; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cdk5 and Its Activator p35 in Neuronal Morphogenesis and Synaptic Function


Zhang, Peng; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cyclin-Dependent Kinase 5 and Its Activator p35 Is Crucial for Neuronal Morphogenesis and Synaptic Function


Zhang, Peng; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Targeting Synaptic Dysfunctions in Alzheimer's Disease


Ip, Nancy Yuk-Yu
Conference paper

The Role of Axin in Dendrite and Spine Development


Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

The Role of Axin in Dendrite and Spine Development


Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

The Role of Liprinα1 in Activity-Dependent Regulation of Synapse Development


Huang, Huiqian; Lai, K.O.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

The Role of Nuclear Cdk5 in Activity-induced Gene Expression during Dendrite Development


Liang, Zhuoyi; Chen, Yu; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper
2013 23

Axin Directs the Amplification and Differentiation of Intermediate Progenitors in the Developing Cerebral Cortex

Neuron, v. 79, (4), August 2013, p. 665-679
Fang, Weiqun; Chen, Weiwei; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Axin: An emerging key scaffold at the synapse

IUBMB Life, v. 65, (8), August 2013, p. 685-691
Chen, Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

Cdk5 Phosphorylates a Component of the HDAC Complex and Regulates Histone Acetylation during Neuronal Cell Death

NeuroSignals, v. 21, (1-2), February 2013, p. 55-60
Fu, Kit Yu; Hung, Kwok Wang; Wong, Hovy Ho-Wai; Fu, Wing Yu; Ip, Nancy Y.Y.
Article

Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors

Bioorganic and Medicinal Chemistry, v. 21, (3), February 2013, p. 676-683
Hu, Yueqing; Zhang, Jun; Chandrashankra, Oormila; Ip, Fanny C.F.; Ip, Nancy Y.
Article

Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-Dependent Mechanism

Journal of Neuroscience, v. 33, (2), January 2013, p. 464-472
Shen, Yang; Fu, Wing-Yu; Cheng, Elaine Y.L.; Fu, Amy K.Y.; Ip, Nancy Y.
Article

Olean-12-Eno[2,3-c] [1,2,5]Oxadiazol-28-Oic Acid (OEOA) Induces G1 Cell Cycle Arrest and Differentiation in Human Leukemia Cell Lines

PLoS ONE, v. 8, (5), May 2013, article number e63580
Ng, Yu Pong; Chen, Yuewen; Hu, Yueqing; Ip, Fanny Chui Fun; Ip, Nancy Yuk Yu
Article

Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders

Biochimica et Biophysica Acta - Molecular Basis of Disease, v. 1832, (12), December 2013, p. 2257-2263
Lai, Kwok-On; Ip, Nancy Yuk Yu
Article

Telomerase Inhibition Studies of Novel Spiroketal-Containing Rubromycin Derivatives

Australian Journal of Chemistry, v. 66, (5), 2013, p. 530-533
Yuen, Tsz-Ying; Ng, Yu-Pong; Ip, Fanny C.F.; Chen, Jack L.Y.; Atkinson, Darcy J.; Sperry, Jonathan; Ip, Nancy Y.; Brimble, Margaret A.
Article

The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics

Journal of Biological Chemistry, v. 288, (27), July 2013, p. 20034-20045
Xiao, Yangui; Peng, Yinghui; Wan, Jun; Tang, Genyun; Chen, Yuewen; Tang, Jing; Ye, Wen-Cai; Ip, Nancy Y.; Shi, Lei
Article

Activity-Dependent Phosphorylation of p70 Ribosomal s6 Kinase (p70S6K) by Cdk5 Is Required for Dendritic Spine Maturation


Lai, Kwok On; Fei, Erkang; Ip, Nancy Yuk-Yu
Conference paper

Axin Regulates Dendrite and Spine Development in Hippocampal Neurons


Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-dependent Phosphorylation of Mst3 Regulates Radial Migration through Modulating RhoA Activity


Tang, Jing; Ip, Jacque Pak Kan; Fang, Weiqun; Zhong, Wanting; Ng, Yu Pong; Wu, Zhenguo; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

From Understanding Neural Plasticity to Drug Discovery for Neurodegenerative Diseases


Ip, Nancy Yuk-Yu
Conference paper

From Understanding Synaptic Plasticity to Drug Discovery for Neurogenerative Diseases


Ip, Nancy Yuk-Yu
Conference paper

Inhibition of EphA4 Signaling Reverses the Abeta-induced Synaptic Deficits in the Hippocampus


Fu, Amy Kit Yu; Hung, Kwok Wang; Huang, Huiqian; Gu, Shuo; Shen, Yang; Cheng, Elaine; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Multidisciplinary Approaches to Combating Brain Disorders


Ip, Nancy Yuk-Yu
Conference paper

Role of Nuclear Cdk5 in Activity-induced Dendrite Development


Liang, Zhuoyi; Chen, Yu; Cai, Y.L.; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Small Molecule Antagonist of Prostaglandin E2 Receptor Ameliorates Experimental Autoimmune Encephalomyelitis


Ip, Fanny Chui Fun; Ng, Yu Pong; Ye, W.C.; Ip, Nancy Yuk-Yu
Conference paper

Stem Cell Strategy for Nervous System Disorders


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Undertaking Innovative Research in China: In Search of New Molecular Targets for Alzheimer's Disease


Ip, Nancy Yuk-Yu
Conference paper
2012 32

Ankyrin repeat-rich membrane spanning protein (Kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development

Journal of Neuroscience, v. 32, (24), June 2012, p. 8263-8269
Chen, Yu; Fu, Ada W.Y.; Ip, Pak Kan; Ye, Tao; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Y.
Article

Astragaloside IV and Cycloastragenol Stimulate the Phosphorylation of Extracellular Signal-Regulated Protein Kinase in Multiple Cell Types

Planta Medica, v. 78, (2), January 2012, p. 115-121
Yung, Ying Lisa; Lam, Wing See; Ho, Maurice K.C.; Hu, Sharry Y.; Ip, Fanny C.F.; Pang, Haihong; Chin, Allison; Harley, Calvin B.; Ip, Nancy Yuk-yu; Wong, Yung Hou
Article

Cdk5: a multifaceted kinase in neurodegenerative diseases

Trends in Cell Biology, v. 22, (3), March 2012, p. 169-175
Cheung, Zelda H.; Ip, Nancy Y.
Article

Cyclin-Dependent Kinase 5 in Axon Growth and Regeneration

International Review of Neurobiology, v. 105, December 2012, p. 91-115
Ye, Tao; Fu, Kit Yu; Ip, Nancy Y.
Article

Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons

Experimental Neurology, v.233, (2), 2012, p. 791-798
Huang, Ying; Ko, Ho; Cheung, Zelda H.; Yung, Ken Kin Lam; Yao, Tai; Wang, Jianjun; Morozov, Alexei; Ke, Ya; Ip, Nancy Yuk-yu; Yung, Wingho
Article

Eph receptors at synapses: Implications in neurodegenerative diseases

Cellular Signalling, v. 24, (3), March 2012, p. 606-611
Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Guidelines for the use and interpretation of assays for monitoring autophagy

Autophagy, v. 8, (4), 2012, p. 445-544
Klionsky, Daniel J.; Ip, Nancy Yuk-yu
Article

Molecular mechanisms underlying maturation and maintenance of the vertebrate neuromuscular junction

Trends in Neurosciences, v.35, (7), July 2012, p. 441-453
Shi, Ling; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function

Cell Death and Differentiation, v. 19, (2), 2012, p. 257-266
Fitzgerald, J.C.; Camprubi, M.D.; Dunn, L.; Wu, H.C.; Ip, N.Y.; Kruger, R.; Martins, L.M.; Wood, N.W.; Plun-Favreau, H.
Article

TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory

Nature Neuroscience, v.15, (11), 2012, Nov, p. 1506-1515
Lai, Kwok On; Wong, Alan S.L.; Cheung, Man Chun; Xu, Pei; Liang, Zhuoyi; Lok, Ka Chun; Xie, Hui; Palko, Mary E.; Yung, Wing-Ho; Tessarollo, Lino; Cheung, Zelda H.Y.; Ip, Nancy Y.Y.
Article

α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2

Nature Neuroscience, v.15, (1), January 2012, p. 39-47
Ip, Pak Kan; Shi, Lei; Chen, Yu; Itoh, Yasuhiro; Fu, Wing Yu; Betz, Andrea; Yung, Wing-Ho; Gotoh, Yukiko; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Cyclin-Dependent Kinase 5 – an Emerging Player in Parkinson's Disease Pathophysiology

Mechanisms in Parkinson's Disease - Models and Treatments / Edited by Juliana Dushanova. InTechOpen, 2012, p. 141-156
Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Book chapter

Eph Receptor

Encyclopedia of Signaling Molecules / Edited by Sangdun Choi. Springer International Publishing, 2012, p. 560-567
Lai, Kwok On; Ip, Nancy Yuk-Yu
Book chapter

Axin Regulates the Balance Between Proliferation and Neuronal Differentiation of Neural Precursor Cells


Fang, Weiqun; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Dependent Regulation of Rap1 Signaling in Cortical Neuronal Migration


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

CM-Based Drug Discovery for Neurodegenerative Diseases


Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of cdk5 in Rap1 Signaling During Neuronal Migration


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Mst3 in Radial Migration During Mouse Cerebral Cortex Development


Tang, J.; Ip, J.P.K.; Fang, W.Q.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Mst3 in Radial Migration During the Development of Mouse Cerebral Cortex


Tang, Jing; Ip, Pak Kan; Fang, Weiqun; Zhong, Weiting; Ng, Yu Pong; Wu, Zhenguo; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Y.; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Nucleocytoplasmic Shuttling of Axin Balances Proliferation and Neuronal Differentiation of Neural Progenitor Cells


Fang, W.Q.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

P39-Associated Cdk5 Activity Regulates Dendrite Development


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

P39-Associated Cdk5 Activity Regulates Dendrite Growth in Neuronal Development


Fu, Amy Kit Yu; Chen, Yu; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Role of Cdk5 in Activity-Dependent Dendrite Development and Spine Morphogenesis


Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Roles of a2-Chimaerin in Neural Circuit Wiring and Function


Fu, Kit Yu; Min, L.; Yung, W.H.; Ip, J.P.K.; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) and Its Activator in Neural Development.


Zhang, Peng; Ip, Pak Kan; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) and Its Activator p35 Regulate Neural Development


Zhang, P.; Ip, J.P.K.; Fu, W.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Understanding Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Α2-Chimaerin Is Required for Proper Functioning of Neural Circuits


Ip, Pak Kan; Yung, Wing Ho; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper
2011 27

A New Carotenoid Glycoside from Rehmannia Glutinosa

Natural Product Research, v.25, (13), August 2011, p. 1213-1218
Fu, Guangmiao; Shi, Shepo; Ip, Fanny C.F.; Pang, Haihong; Ip, Nancy Yuk-yu
Article

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

Nature Neuroscience, v. 14, (2), February 2011, p. 181-191
Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-yu
Article

Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives

Journal of Neurochemistry, v.118, (3), August 2011, p. 317-325
Cheung, Zelda H.; Ip, Nancy Yuk-yu
Article

Career Development for Women Scientists in Asia

Neuron, v. 70, (6), June 2011, p. 1029-1032
Ip, Nancy Y.
Article

Cdk5-Mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development

Journal of Neuroscience, v. 31, (38), September 2011, p. 13613-13624
Fang, Wei-Qun; Ip, Jacque P.K.; Li, Rui; Ng, Yu Pong; Lin, Shengcai; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

Nature Cell Biology, v. 13, (5), May 2011, p. 568-579
Wong, Alan S.L.; Lee, Rebecca H.K.; Cheung, Anthony Y.; Yeung, Patrick K.; Chung, Sookja K.; Cheung, Zelda H.; Ip, Nancy Yuk-yu
Article

Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development

Neuroscience, v.180, April 2011, p. 353-359
Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Expression of Gαz in C2C12 Cells Restrains Myogenic Differentiation

Cellular Signalling, v. 23, (2), February 2011, p. 389-397
Mei, Hua; Ho, Kwok Chung Maurice; Yung, Ying; Wu, Zhenguo; Ip, Nancy Yuk-yu; Wong, Yung Hou
Article

From Understanding Synaptic Plasticity to the Development of Cognitive Enhancers

International Journal of Neuropsychopharmacology, v. 14, (9), October 2011, p. 1247-1256
Cheung, Zelda Hiu Yee; Ip, Nancy Yuk-yu
Article

Intestinal Transport of Bis(12)-hupyridone in Caco-2 Cells and its Improved Permeability by the Surfactant Brij-35

Biopharmaceutics & Drug Disposition, v. 32, (3), April 2011, p. 140-150
Yu, Hua; Hu, Yue Qing; Ip, Fanny C.F.; Zuo, Zhong; Han, Yi Fan; Ip, Nancy Yuk-yu
Article

Molecular machinery of macroautophagy and its deregulation in diseases

Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1812, (11), November 2011, p. 1490-1497
Wong, Alan S.L.; Cheung, Zelda H Y; Ip, Nancy Yuk-yu
Article

Natural products targeting telomere maintenance

MedChemComm, v. 2, (4), April 2011, p. 229-245
Chen, Jack Li-Yang; Sperry, Jonathan; Ip, Nancy Y.; Brimble, Margaret A.
Article

Scapinin-induced Inhibition of Axon Elongation Is Attenuated by Phosphorylation and Translocation to the Cytoplasm

Journal of Biological Chemistry, v. 286, (22), June 2011, p. 19724-19734
Farghaian, Hovik; Chen, Yu; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Pak Kan; Ip, Nancy Yuk-yu; Turnley, Ann M.; Cole, Adam R.
Article

Triterpenoids with neurotrophic activity from Ganoderma lucidum

Natural Product Research, v. 25, (17), 2011, p. 1607-1613
Zhang, X.Q.; Ip, Fanny C.F.; Zhang, Dongmei; Chen, Lixin; Zhang, W.; Li, Yaolan; Ip, Nancy Yuk-yu; Ye, Wencai
Article

A2-Chimaerin Regulates Crmp-2 Activity to Control Cortical Neuronal Migration


Ip, J.P.; Shi, L.; Itoh, Y.; Fu, Wing Yu; Gotoh, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Axon Formation in Cerebral Cortex Through Phosphorylation of Axin


Fu, Kit Yu; Fang,W-Q; Ip, J.P.; Li, R.; Lin,S-C; Chen, Y.; Ip, Nancy Yuk-Yu
Conference paper

EphB Receptor Regulates Glutamatergic Synaptogenesis Through a Cdk5-Dependent Mechanism


Chen, Y.; Wong, H.; Fu, WY; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

From Understanding Neural Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu
Conference paper

From Understanding Neural Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Melanocortin-4 Receptor in Synapse Maintenance


Shen, Y.; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Mst3 in Radial Migration During the Development of Mouse Cerebral Cortex


Tang, J.; Ip, J.P.; Shi, L.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cdk5 Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development


Zhang, P.; Yu,P-C; Tsang, A.H.; Chen, Y.; Fu, Kit Yu; Fu, WY; Chung, Kenny Ka Kin; Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper
2010 38

Avian influenza H5N1 virus induces cytopathy and proinflammatory cytokine responses in human astrocytic and neuronal cell lines

Neuroscience, v. 168, (3), July 2010, p. 613-623
Ng, Yu Pong; Lee, S.M.Y.; Cheung, T.K.W.; Nicholls, J.M.; Peiris, J.S.M.; Ip, Nancy Yuk-Yu
Article

Cdk5-Mediated Phosphorylation of delta-Catenin Regulates Its Localization and GluR2-Mediated Synaptic Activity

Journal of Neuroscience, v. 30, (25), June 2010, p. 8457-8467
Poore, Charlene P.; Sundaram, Jeyapriya R.; Pareek, Tej K.; Fu, Amy; Amin, Niranjana; Mohamed, Nur Ezan; Zheng, Ya-Li; Goh, Angeline X.H.; Lai, Mitchell K.; Ip, Nancy Yuk-Yu; Pant, Harish C.; Kesavapany, Sashi
Article

Dammarane saponins from Gynostemma pentaphyllum

Phytochemistry, v. 71, (10), July 2010, p. 1149-1157
Hu, Yongmei; Ip, Fanny C.F.; Fu, Guangmiao; Pang, Haihong; Ye, Wencai; Ip, Nancy Yuk-Yu
Article

Ephexin1 Is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction

Neuron, v. 65, (2), January 2010, p. 204-216
Shi, Lei; Butt, Busma; Ip, Fanny C.F.; Dai, Ying; Jiang, Liwen; Yung, Wing-Ho; Greenberg, Michael E.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Article

In vitro Intestinal Absorption and First-pass Intestinal and Hepatic Metabolism of Cycloastragenol, a Potent Small Molecule Telomerase Activator

Drug Metabolism and Pharmacokinetics, v. 25, (5), November 2010, p. 477-486
Zhu, Jing; Lee, Stephanie; Ho, Maurice K.C.; Hu, Yueqing; Pang, Haihong; Ip, Fanny C.F.; Chin, Allison C.; Harley, Calvin B.; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Article

Multiple Roles of the Rho GEF Ephexin1 in Synapse Remodeling

Communicative & Integrative Biology, v. 3, (6), 2010, p. 622-624
Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Nerve Growth Factor-Induced Differentiation of PC12 Cells Is Accompanied by Elevated Adenylyl Cyclase Activity

NeuroSignals, v. 18, (1), September 2010, p. 32-42
Yung, H.S.; Lai, K.H.; Chow, Kevin B.S.; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung; Wong, Yung Hou; Wu, Zhenguo; Wise, Helen
Article

New Secoiridoid Glucosides from Ligustrum lucidum Induce ERK and CREB Phosphorylation in Cultured Cortical Neurons

Planta Medica, v. 76, (10), July 2010, p. 998-1003
Fu, Guangmiao; Ip, Fanny C.F.; Pang, Haihong; Ip, Nancy Yuk-Yu
Article

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development

Journal of Neuroscience, v. 30, (43), October 2010, p. 14366-14370
Zhang, Peng; Yu, Peichun; Tsang, Anthony H.K.; Chen, Yu; Fu, Kit Yu; Fu, Wing Yu; Chung, Kenny K.K.; Ip, Nancy Yuk-Yu
Article

Trophic Factors: 50 Years of Growth

Developmental Neurobiology, v. 70, April 2010, p. 269-270
Chao, Moses V.; Ip, Nancy Yuk-Yu
Article

Two Cyclin-Dependent Kinase Pathways Are Essential for Polarized Trafficking of Presynaptic Components

Cell, v. 141, (5), May 2010, p. 846-858
Ou, Chan-Yen; Poon, Vivian Y.; Maeder, Celine I.; Watanabe, Shigeki; Lehrman, Emily K.; Fu, Amy K.Y.; Park, Mikyoung; Fu, Wing-Yu; Jorgensen, Erik M.; Ip, Nancy Yuk-Yu; Shen, Kang
Article

Tyk2/STAT3 Signaling Mediates beta-Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease

Journal of Neuroscience, v. 30, (20), May 2010, p. 6873-6881
Wan, Jun; Fu, Kit Yu; Ip, Fanny Chui Fun; Ng, Ho Keung; Hugon, Jacques; Page, Guylène K.; Wang, Jerry Hsueh-ching; Lai, Kwok On; Wu, Zhenguo; Ip, Nancy Yuk-yu
Article

Alpha2-Chimaerin Regulates Neuronal Polarization and Spine Development


Shi, Lei; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Antidepressant-Like Effect of a Refined-Fraction From MNC17 and the Isolation of Active Compounds


Ip, Fanny C.F.; Tong, Estella P.S.; Dai, Ying; Guo, Shengjun; Ip, Nancy Yuk-Yu
Conference paper

Arms/Kidins220 Regulates Dendritic Development Through Ephrin and Neurotrophin Signaling


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

Avian Influenza H5N1 Virus Induces Cytopathy and Proinflammatory Cytokine Responses in Human Astrocytic and Neuronal Cell Lines


Ng, Yu Pong; Lee, Suki M.Y.; Cheung, Timothy K.W.; Nicholls, John M.; Peiris, Malik J.S.; Ip, Nancy Yuk-Yu
Conference paper

Axin Directs Axon Formation Through Its Interaction With GSK-3beta


Fang, Weiqun; Ip, Pak Kan; Li, Rui; Ng, Yu Pong; Lin, S.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Is a Key Regulator in Dendrite Development


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Dependent Phosphorylation of Axin Is Important for Axon Development


Fang, Weiqun; Ip, Jacque P.K.; Li, Rui; Ng, Yu Pong; Lin, S.C.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Dependent Phosphorylation of Endophilin B1 Is Involved in Autophagy Induction in Neurons


Wong, Alan S.L.; Lee, Hui Kwan Rebecca; Cheung, Anthony Y.; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Mediated Phosphorylation of Endophilin B1 Plays a Role in Autophagy Deregulation in Parkinson's Disease Model


Cheung, Zelda H.Y.; Wong, Alan S.L.; Lee, Hui Kwan Rebecca; Cheung, Anthony Y.; Yeung, Patrick K.; Chung, Sookja K.; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Mediated Phosphorylation of Endophilin B1 Plays a Role in Autophagy Deregulation in Parkinson's Disease Model


Cheung, Zelda H.Y.; Wong, Alan S.L.; Lee, Hui Kwan Rebecca; Cheung, Anthony Y.; Yeung, Patrick K.; Chung, Sookja K.; Ip, Nancy Yuk-Yu
Conference paper

Compound A2287 Rescues Primary Neurons Against NMDA Excitotoxicity and Reduces Cerebral Infarct in a Rodent Stroke Model


Ip, Fanny C.F.; Zhao, Yuming; Cheng, Yee Ling; Zhu, H.; Ip, Nancy Yuk-Yu
Conference paper

Elucidating the Role of Cdk5 in Protein Synthesis During Synaptic Plasticity


Lai, Kwok On; Cheung, Man Chun; Ip, Nancy Yuk-Yu
Conference paper

Elucidating the Role of Cdk5 in Protein Synthesis During Synaptic Plasticity


Lai, Kwok On; Cheung, Man Chun; Xu, P.; Cheung, Zelda H Y; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Dependent Degradation of AMPA Receptor Is Important for the Homeostatic Synaptic Plasticity


Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Epha4-Dependent Signaling Regulates the Expression of AMPA Receptor in Homeostatic Plasticity


Fu, Kit Yu; Hung,K-W; Fu, Wing Yu; Shen, C.; Chen, Y.; Xia, J.; Lai,K-O; Ip, Nancy Yuk-Yu
Conference paper

From Understanding Neural Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu
Conference paper

From Understanding the Molecular Basis of Synaptic Plasticity to Discovery of Novel Neuroactive Compounds


Ip, Nancy Yuk-Yu
Conference paper

Identification of a Compound From the Traditional Chinese Medicine With Antidepressant-Like Property


Fu, Wing Yu; Liang, Johnny Y.; Gong, Ke; Zhan, L.; Lai, Kwok On; Ip, Fanny C.F.; Ip, Nancy Yuk-Yu
Conference paper

Identification of Cyclin-Dependent Kinase-5 Inhibitors From Traditional Chinese Medicine


Fu, Wing Yu; Cheng, Yee Ling; Ip, Fanny C.F.; Ip, Nancy Yuk-Yu
Conference paper

Involvement of Cdk5 and Endophilin B1 in Autophagy Induction in Neurons and in Parkinson's Disease Model


Wong, Alan S.L.; Lee, Hui Kwan Rebecca; Cheung, Anthony Y.; Yueng, Patrick K.; Chung, Sookja K.; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Conference paper

Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Molecular Basis of Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Dependent Signaling in Neural Circuit Assembly


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Mediated Signaling in Neural Circuit Assembly


Ip, Nancy Yuk-Yu
Conference paper

Regulation of Cyclin-Dependent Kinase-5 Activity by S-Nitrosylation


Fu, Wing Yu; Zhang, Peng; Tsang, Anthony H.K.; Xie, S.Y.; Fu, Kit Yu; Chung, Kenny K K; Ip, Nancy Yuk-Yu
Conference paper

Α2-Chimaerin Regulates Laminar Positioning in the Cerebral Cortex


Ip, Jacque P.K.; Shi, Lei; Itoh, Y.; Fu, Wing Yu; Gotoh, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper
2009 26

Differential and Synergistic Effect of Nerve Growth Factor and cAMP on the Regulation of Early Response Genes during Neuronal Differentiation

NeuroSignals, v. 17, (2), May 2009, p. 111-120
Ng, Yu Pong; Wu, Zhenguo; Wise, Helen; Tsim, Karl Wah Keung; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Article

Endophilin B1. Guarding the gate to destruction

Communitative and Integrative Biology, v. 2, (2), January 2009, p. 130-132
Cheung, Zelda Hiu Yee; Ip, Nancy Yuk-Yu
Article

Identification of retinoic acid-regulated nuclear matrix-associated protein as a novel regulator of gastric cancer

British Journal of Cancer, v. 101, (4), August 2009, p. 691-698
Li, J.; Ng, E.K.O.; Ng, Yu Pong; Wong, C.Y.P.; Yu, J.; Jin, H.; Cheng, V.Y.Y.; Go, M.Y.Y.; Cheung, P.K.F.; Ebert, M.P.A.; Tong, J.; To, K.F.; Chan, F.K.L.; Sung, J.J.Y.; Ip, Nancy Yuk-Yu; Leung, W.K.
Article

Induction of Proinflammatory Cytokines in Primary Human Macrophages by Influenza A Virus (H5N1) Is Selectively Regulated by IFN Regulatory Factor 3 and p38 MAPK

Journal of Immunology, v. 182, (2), January 2009, p. 1088-1098
Hui, Kenrie P.Y.; Lee, Suki M.Y.; Cheung, Chung-yan; Ng, Iris H.Y.; Poon, Leo L.M.; Guan, Yi; Ip, Nancy Yuk-Yu; Lau, Allan S.Y.; Peiris, J. S. Malik
Article

Multiple Gi Proteins Participate in Nerve Growth Factor-Induced Activation of c-Jun N-terminal Kinases in PC12 Cells

Neurochemical Research, v. 34, (6), June 2009, p. 1101-1112
Tso, Ha; Morris, Christina Jane; Yung, Ying; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Article

Recent advances in understanding the roles of Cdk5 in synaptic plasticity

Biochimica et Biophysica Acta - Molecular Basis of Disease, v. 1792, (8), August 2009, p. 741-745
Lai, Kwok On; Ip, Nancy Yuk-Yu
Article

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

Current Opinion in Neurobiology, v. 19, (3), June 2009, p. 275-283
Lai, Kwok On; Ip, Nancy Yuk-Yu
Article

Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages

PloS one, v. 4, (12), December 2009, article number e8072
Lee, Suki M.Y.; Gardy, Jennifer L.; Cheung, C.Y.; Cheung, Timothy K.W.; Hui, Kenrie P.Y.; Ip, Nancy Y.; Guan, Y.; Hancock, Robert E.W.; Peiris, J. S. Malik
Article

The emerging role of autophagy in Parkinson's disease

Molecular Brain, v. 2, (1), September 2009, article number 29
Cheung, Zelda Hiu Yee; Ip, Nancy Yuk-Yu
Article

Axin Plays an Essential Role in Neuronal Polarization


Fang, Weiqun; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Axin Plays an Essential Role in Neuronal Polarization


Fang, Weiqun; Lin, S.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdh1 Is Required for Synapse Development and Function


Fu, Wing Yu; Hung, Kwok Wang; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdh1-Dependent Degradation of Postsynaptic Proteins Is Important for Synapse Development and Functions


Fu, Wing Yu; Hung, Kwok Wang; Shi, Lei; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Is Required for BDNF-Induced Spine Morphogenesis in Hippocampal Neurons


Cheung, Zelda H.Y.; Xu, Pei; Xie, Hui; Yung, Wing H.; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates the Histone Acetylation During Neuronal Apoptosis


Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cyclin Dependent Kinase 5 Phosphorylation of Delta-Catenin Mediates Its Subcellular Localisation in Neurons


Poore, C.P.; Sundram, J.R.; Pareek, T.K.; Fu, Kit Yu; Ip, Nancy Yuk-Yu; Pant, H.C.; Kesavapany, S.
Conference paper

EphA4-Mediated Degradation of AMPA Receptor Is Important in Homeostatic Synaptic Plasticity


Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Ephexin1 Promotes Postsynaptic Maturation at the Neuromuscular Junction


Shi, Lei; Butt, Busma Wai Yin; Ip, Fanny C.F.; Dai, Ying; Greenberg, M.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

From Understanding Synaptic Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu
Conference paper

Molecular Basis of Neuronal Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Molecular Basis of Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Molecular Basis of Synaptic Plasticity: Roles of Cdk5


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Regulation of APP metabolism by the Rho GTPase cdc42


Steele, J.W.; Ip, Nancy Yuk-Yu; Thinakaran, G.; Tanzi, R.; Ehrlich, M.E.; Gandy, S.E.
Conference paper

Screening of Essential Kinases for Neuronal Differentiation


Ng, Yu Pong; Lai, Kwok On; An, Hui Jin; Wu, Zhenguo; Ip, Nancy Yuk-Yu
Conference paper
2008 40

Bidirectional signaling of ErbB and Eph receptors at synapses

Neuron Glia Biology, v. 4, (3), August 2008, p. 211-221
Chen, Yu; Fu, Kit Yu; Ip, Nancy Y.
Article

CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5

FEBS Letters, v. 582, (8), April 2008, p. 1197-1202
Lin, Shuyong; Wang, Jifeng; Ye, Zhiyun; Ip, Nancy Yuk-Yu; Lin, Sheng-Cai
Article

Cyclin-Dependent Kinase 5 Supports Neuronal Survival through Phosphorylation of Bcl-2

Journal of Neuroscience, v. 228, (19), May 2008, p. 4872-4877
Cheung, Zelda H.; Gong, Ke; Ip, Nancy Yuk-Yu
Article

Endophilin B1 as a novel regulator of nerve growth factor/TrkA trafficking and neurite outgrowth

Journal of Neuroscience, v. 28, (36), September 2008, p. 9002-9012
Wan, Jun; Cheung, Anthony Y.; Fu, Wing Yu; Wu, Chengbiao; Zhang, Mingjie; Mobley, William C.; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Article

Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection

Journal of Infectious Diseases, v. 198, (4), August 2008, p. 525-535
Lee, Suki M.Y.; Cheung, Chung-Yan; Nicholls, John M.; Hui, Kenrie P.Y.; Leung, Connie Y.H.; Uiprasertkul, Mongkol; Tipoe, George L.; Lau, Yu-Lung; Poon, Leo L.M.; Ip, Nancy Yuk-Yu; Guan, Yi; Peiris, J. S. Malik
Article

Nerve growth factor-induced stimulation of p38 mitogen-activated protein kinase in PC12 cells is partially mediated via Gi/o proteins

Cellular Signalling, v. 20, (8), August 2008, p. 1538-1544
Yung, Ying; Tso, Ha; Wu, Eddy H.T.; Yu, Jowie C.H.; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Article

Neurotrophins - players in the regulation of neuronal survival and apoptosis

Current Science, v. 95, (9), November 2008, p. 1237-1251
Cheung, Zelda Hiu Yee; Ip, Nancy Yuk-Yu
Article

Recent development in the search for effective antidepressants using traditional Chinese medicine

Central Nervous System Agents in Medicinal Chemistry, v. 8, (1), 2008, p. 64-71
Pang, Tracy Haihong; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

β-catenin in reverse action

Nature Neuroscience, v. 11, (3), 2008, p. 244-246
Fu, Kit Yu; Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Article

受體酪氨酸激酶依賴的信號轉導在突觸可塑性中的研究

生命科学=Chinese Bulletin of Life Sciences, v. 2008, (05), 2008, p. 709-711
葉玉如
Article

Cyclin Dependent Kinase 5 (Cdk5)


Ip, Nancy Yuk-Yu; Tsai, Li-Huei
Book

Cdk5 in Dendrite and Synapse Development: Emerging Role as a Modulator of Receptor Tyrosine Kinase Signaling

Cyclin Dependent Kinase 5 (Cdk5) / Edited by Nancy Y. Ip, Li-Huei Tsai. New York, NY : Springer US, 2008, p. 51-68
Cheung, Zelda, H.Y.; Ip, Nancy Yuk-Yu
Book chapter

A Herb-Derived Compound Protects Primary Neurons Against N-Methyl-D-Aspartate Excitotoxicity and Attenuates Deficits of Memory-Impaired Mice


Ip, Fanny C F; Tong, E.; Lok, K.; Cheng, E.; Fu, W.; Ip, Nancy Yuk-Yu; Ye, W.
Conference paper

A Transcriptional Regulator NIF-1 Regulates Neurite Outgrowth and Undergoes p35-Dependent Nuclear Export


Zhao, Xiao Su; Fu, Wing Yu; Chien, Winnie W.Y.; Li, Zhen; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Activity Is Required for BDNF-Stimulated Neuronal Survival and Synaptic Plasticity


Xu, Pei; Xie, Hui; Yung, Wing H.; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Dendritic Development in Hippocampal Neurons


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5: A Key Player at Synapses


Ip, Nancy Yuk-Yu
Conference paper

China on the Path Towards and Innovation-Oriented Economy


Ip, Nancy Yuk-Yu
Conference paper

Discovery of Novel Neuroactive Lead Compounds From Traditional Chinese Medicine


Ip, Nancy Yuk-Yu
Conference paper

EphA4 Signaling Regulates the Dispersal of Acetylcholine Receptors Through Activation of ephexin1


Shi, L.; Butt, B.; Greenberg, M.E.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Signaling Regulates the Stability of Agrin-Induced Acetylcholine Receptors Through Activation of Ephexin1


Shi, Lei; Butt, Busma Wai Yin; Greenberg, Michael E.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Signaling Regulates the Stability of Agrin-Induced Acetylcholine Receptors Through Activation of Ephexin1


Shi, Lei; Butt, Busma Wai Yin; Greenberg, Michael E.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Dependent Signaling Regulates the Synaptic Strength of Glutamatergic Synapses


Fu, Kit Yu; Hung, K.W.; Shen, C.; Xia, J.; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

GAlphaz Inhibits Myogenic Differentiation of C2C12 Cells


Ho, Kwok Chung Maurice; Mei, Hua; Yung, Ying; Wu, Zhenguo; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Conference paper

Identification of Endophilin B1 as a Novel Regulator of NGF/TrkA Trafficking and Function


Wan, Jun; Cheung, Anthony Y.; Fu, Wing Yu; Wu, Chengbiao; Zhang, Mingjie; Mobley, William C.; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Conference paper

Identification of Endophilin B1 As a Novel Regulator of NGF/TrkA Trafficking and Function


Wan, Jun; Cheung, Anthony Y.; Fu, Wing Yu; Wu, Chengbiao; Zhang, Mingjie; Mobley, William C.; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Conference paper

Molecular Mechanisms of Neuronal Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Molecular Mechanisms of Synaptic Plasticity and Discovery of Novel Neuroactive Compounds From Traditional Chinese Medicine


Ip, Nancy Yuk-Yu
Conference paper

Molecular Neuroscience: Basic Research and Drug Discovery


Ip, Nancy Yuk-Yu
Conference paper

Molecular Neuroscience: Basic Research and Drug Discovery


Ip, Nancy Yuk-Yu
Conference paper

Molecular Neuroscience: Basic Research and Drug Discovery


Ip, Nancy Yuk-Yu
Conference paper

Molecular Neuroscience; Basic Research and Drug Discovery


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu
Conference paper

Regulation of Synapse Development by Receptor Tyrosine Kinase Signaling


Ip, Nancy Yuk-Yu
Conference paper

Unlocking the Mysteries of the Brain


Ip, Nancy Yuk-Yu
Conference paper

Women Scientists Surpassing Boundaries: My Road to Becoming a Neuroscientist


Ip, Nancy Yuk-Yu
Conference paper

以中藥為基礎研發抗衰老藥物


葉玉如
Conference paper

神經元可塑性的分子機理


葉玉如
Conference paper

神經退化性疾病: 從基礎研究到藥物開發


葉玉如
Conference paper
2007 24

alpha 2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse

Proceedings of the National Academy of Sciences of the United States of America, v. 104, (41), October 2007, p. 16347-16352
Shi, Lei; Fu, Wing Yu; Hung, Kwok Wang; Porchetta, Cassandra; Hall, Christine; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Antibacterial diterpenoids from Sagittaria pygmaea

Planta Medica, v. 73, (1), January 2007, p. 84-90
Liu, Xue-Ting; Shi, Yao; Yu, Biao; Williams, Ian Duncan; Sung, Ho Yung; Zhang, Qiong; Liang, Jing-Yu; Ip, Nancy Yuk-Yu; Min, Zhi-Da
Article

Biotech News on Hong Kong

Asia Pacific Biotech News, v. 11, (4), February 2007, p. 218-220
Ip, Nancy Yuk-Yu
Article

Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons

PLoS Biology, v. 5, (4), April 2007, p. 865-877
Cheung, Zelda Hiu Yee; Chin, Wing Hong; Chen, Yu; Ng, Yu Pong; Ip, Nancy Yuk-Yu
Article

Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism

Nature Neuroscience, v. 10, (1), January 2007, p. 67-76
Fu, Wing Yu; Chen, Yu; Sahin, Mustafa; Zhao, Xiao-Su; Shi, Lei; Bikoff, Jay B.; Lai, Kwok-On; Yung, Wing-Ho; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Article

Cyclin-dependent kinase 5 links extracellular cues to actin cytoskeleton during dendritic spine development

Cell Adhesion & Migration, v. 1, (2), April 2007
Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Differential regulation of the Cdk5-dependent phosphorylation sites of inhibitor-1 and DARPP-32 by depolarization

Journal of Neurochemistry, v. 103, (4), November 2007, p. 1582-1593
Nguyen, Chan; Hosokawa, Tomohisa; Kuroiwa, Mahomi; Ip, Nancy Yuk-Yu; Nishi, Akinori; Hisanaga, Shin-ichi; Bibb, James A.
Article

Expression of G protein beta subunits in rat skeletal muscle after nerve injury: Implication in the regulation of neuregulin signaling

Neuroscience, v. 146, (2), May 2007, p. 594-603
Lok, Ka Chun; Fu, Amy Kit Yu; Ip, Fanny Chun Fun; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Article

JAK1-STAT1-STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts

Journal of Cell Biology, v. 179, (1), October 2007, p. 129-138
Sun, Luguo; Ma, Kewei; Wang, Haixia; Xiao, Fang; Gao, Yan; Zhang, Wei; Wang, Kepeng; Gao, Xiang; Ip, Nancy Yuk-Yu; Wu, Zhenguo
Article

Minor limonoids from Melia toosendan and their antibacterial activity

Planta Medica, v. 73, (12), October 2007, p. 1298-1303
Zhang, Qiong; Shi, Yao; Liu, Xue-Ting; Liang, Jing-Yu; Ip, Nancy Yuk-Yu; Min, Zhi-Da
Article

NRG induces membrane targeting of Gαz in muscle: implication in myogenesis

NeuroReport, v. 18, (14), September 2007, p. 1433-1436
Lok, Ka Chun; Fu, Kit Yu; Ip, Fanny C.F.; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Article

The roles of cyclin-dependent kinase 5 in dendtrite and synapse development

Biotechnology Journal, v. 2, (8), August 2007, p. 949-957
Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Article

一叶萩生物碱类成分研究

中草药=Chinese Traditional and Herbal Drugs, v. 38, (2), February 2007, p. 163-167
王英; 李茜; 葉文才; 葉翠芬; 葉玉如; 趙守訓
Article

Cdk5: A Key Regular of Dendrite and Spine Development


Ip, Nancy Yuk-Yu
Conference paper

Drug Development Candidate TAT2 Activates Telomerase in Primary Neuronal Cultures


An, Hui Jin; Ip, Fanny C.F.; Hu, Sharry Y; Ho, Maurice K C; Chin, A.C.; Harley, C.B.; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Isolation of Neuroprotective Compounds Through Activity-Guided Fractionations of Traditional Chinese Medicine


Ip, Fanny C.F.; Tong, Pui Sze; Chan, Agnes W.S.; Guo, Shengjun; Ip, Nancy Yuk-Yu
Conference paper

Knowledge-Based Drug Discovery: Identification of Lead Candidates From Traditional Chinese Medicine


Ip, Nancy Yuk-Yu
Conference paper

Knowledge-Based Drug Discovery: Identification of Novel Leads From Traditional Chinese Medicine


Pang, Haihong; Hu, Sharry Y.; Ho, Maurice K C; Ip, Fanny C.F.; An, Hui Jin; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Conference paper

Kowledge-Based Drug Discovery at the Biotechnology Research Institute


Ip, Nancy Yuk-Yu
Conference paper

Molecular Neuroscience: Basic Research and Drug Discovery


Ip, Nancy Yuk-Yu
Conference paper

PSR Formula Rescues Primary Cortical Neurons Against NMDA Excitotoxicity


Ip, Fanny C.F.; Tong, Pui Sze; Cheng, Yee Ling; Lee, Venus Wai Sze; Ip, Nancy Yuk-Yu
Conference paper

Regulation of Synapse Development by Receptor Tyrosine Kinase Signaling


Ip, Nancy Yuk-Yu
Conference paper

Regulation of Synapse Development by Receptor Tyrosine Kinase Signaling


Ip, Nancy Yuk-Yu
Conference paper

Regulation of Synapse Development by Receptor Tyrosine Kinase Signaling


Ip, Nancy Yuk-Yu
Conference paper
2006 28

ent-rosane and labdane diterpenoids from Sagittaria sagittifolia and their antibacterial activity against three oral pathogens

Journal of Natural Products, v. 69, (2), February 2006, p. 255-260
Liu, Xue-Ting; Pan, Qin; Shi, Yao; Williams, Ian Duncan; Sung, Ho Yung; Zhang, Qiong; Liang, Jing-Yu; Ip, Nancy Yuk-Yu; Min, Zhi-Da
Article

GABAB heterodimeric receptors promote Ca2+ influx via store-operated channels in rat cortical neurons and transfected chinese hamster ovary cells

Neuroscience, v. 137, (4), 2006, p. 1347-1358
New, David C.; An, Hui Jin; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Article

Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein - Implications in the regulation of its hexamerization and exocytosis

Journal of Biological Chemistry, v. 281, (15), April 2006, p. 9852-9858
Liu, Yuxin; Cheng, Kai; Gong, Ke; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

STAT3 as a downstream mediator of Trk signaling and functions

Journal of Biological Chemistry, v. 281, (23), June 2006, p. 15636-15644
Ng, Yu Pong; Cheung, Zelda Hiu Yee; Ip, Nancy Yuk-Yu
Article

Synaptic roles of Cdk5: Implications in higher cognitive functions and neurodegenerative diseases

Neuron, v. 50, (1), April 2006, p. 13-18
Cheung, Zelda H.; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

一叶萩的化学成分

中國天然藥物=Chinese Journal of Natural Medicines, v. 4, (4), July 2006, p. 260-263
王英; 李茜; 葉文才; 葉翠芬; 葉玉如; 趙守訓
Article

Signaling through the neurotrophin receptors

Handbook of Neurochemistry and Molecular: Neurobiology Neuroactive Proteins and Peptides / Abel Lajtha, Editor; Ramon Lim, Volume Editor. Germany : Springer, 2006, p. 11-41
Ng, Yu Pong; Lo, Kin Yip; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Book chapter

Activity-Guided Fractionations of Chinese Herbs for Isolation of Neuroprotective Compounds


Ip, Fanny C.F.; Woo, Florence L.C.; Chan, Agnes W.S.; Tong, Pui Sze; Guo, Shengjun; Ip, Nancy Yuk-Yu
Conference paper

ANKRA2 Interacts With p35 and Regulates Gene Transcription


Ng, Alberto K.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

ARMS Regulates Dendritic Development in Hippocampal Neurons


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

ARMS Regulates Dendritic Development in Hippocampal Neurons


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

Axin Is Involved in Nerve Growth Factor-Induced Differentiation of PC12 Cells


Ng, Yu Pong; Lin, Shengcai; Fu, Kit Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Is Involved in BDNF-Stimulated Dendritic Growth in Hippocampal Neurons


Cheung, Zelda H.Y.; Chin, Wing Hong; Chen, Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Is Involved in BDNF-Stimulated Dendritic Growth in Hippocampal Neurons


Cheung, Zelda H.Y.; Chin, Wing Hong; Chen, Yu; Ng, Yu Pong; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Mitochondrial Function Through a Cdk5RAP1-Dependent Mechanism


Wong, Grace K.W.; Fu, Kit Yu; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Cdk5: A Key Regulator of Synaptic Functions


Ip, Nancy Yuk-Yu
Conference paper

Cdk5: A Key Regulator of Synaptic Functions


Ip, Nancy Yuk-Yu
Conference paper

EphA4 Induces Dendritic Spine Retraction Through a Cdk5-Dependent Mechanism


Fu, Wing Yu; Chen, Yu; Sahin, Mustafa; Zhao, Xiaosu; Shi, Lei; Bikoff, Jay B.; Lai, Kwok On; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Induces Dendritic Spine Retraction Through a Cdk5-ephexin1-Dependent Mechanism


Fu, Wing Yu; Chen, Yu; Sahin, Mustafa; Zhao, Xiao Su; Shi, Lei; Bikoff, Jay B.; Lai, Kwok On; Yung, Wing Ho; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Mediated Signaling Regulates the Aggregation of AChRs Stimulated by Agrin


Shi, Lei; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Mediated Signaling Regulates the Agrin-Stimulated Aggregation of AChRs in C2C12 Myotubes


Shi, Lei; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of STAT3 as a Novel Regulator of TRK Signaling and Functions


Ng, Yu Pong; Cheung, Zelda H.Y.; Ip, Nancy Yuk-Yu
Conference paper

NRC-Interacting Factor 1 (NIF-1) Associates With p35 and Is Involved in Neuronal Differentiation


Zhao, Xiao Su; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

NRG-ErbB Signaling: Recent Insights in the Regulation of Gene Transcription


Ip, Nancy Yuk-Yu
Conference paper

Post-synaptic Signaling of New Players at the Synapse


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Mediated Signaling at the Synapse


Ip, Nancy Yuk-Yu
Conference paper

Receptor Tyrosine Kinase-Mediated Signaling at the Synapse


Ip, Nancy Yuk-Yu
Conference paper

Role of Axin in Nerve Growth Factor-Induced Differentiation of PC12 Cells


Ng, Yu Pong; Lin, Shengcai; Fu, Kit Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper
2005 29

A DNA microarray for the authentication of toxic traditional Chinese medicinal plants

Planta Medica, v. 71, (6), June 2005, p. 580-584
Carles, Maria C.; Cheung, Kin Lok; Moganti, Shanti; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Sucher, Nikolaus J.
Article

Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice

Proceedings of the National Academy of Sciences of the United States of America, v. 102, (42), October 2005, p. 15224-15229
Fu, Amy Kit Yu; Ip, Fanny Chun Fun; Fu, Wing Yu; Cheung, Janet; Wang, Jerry H.; Yung, Wing-Ho; Ip, Nancy Yuk-Yu
Article

Agrin regulates growth cone turning of Xenopus spinal motoneurons

Development, v. 132, (19), October 2005, p. 4309-4316
Xu, Xiaohua; Fu, Amy Kit Yu; Ip, Fanny Chun Fun; Wu, Chien-ping; Duan, Shumin; Poo, Mu-ming; Yuan, Xiao-bing; Ip, Nancy Yuk-Yu
Article

alpha-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner

Journal of Cell Biology, v. 169, (5), June 2005, p. 813-824
Luo, Shuo; Chen, Yu; Lai, Kwok On; Arevalo, Juan C.; Froehner, Stanley C.; Adams, Marvin E.; Chao, Moses V.; Ip, Nancy Yuk Yu
Article

Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem

Nature Structural & Molecular Biology, v. 12, (8), August 2005, p. 722-728
Long, Jiafu; Feng, Wei; Wang, Rui; Chan, Ling Nga; Ip, Fanny C.F.; Xia, Jun; Ip, Nancy Yuk-Yu; Zhang, Mingjie
Article

Cytotoxic diterpenoids from the roots of Euphorbia ebracteolata

Planta Medica, v. 71, (4), April 2005, p. 349-354
Shi, Hai Ming; Williams, Ian D.; Sung, Herman H.Y.; Zhu, HX; Ip, Nancy Yuk-Yu; Min, Zhi-Da
Article

Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex

Journal of Neuroscience, v. 25, (20), May 2005, p. 4979-4984
Gu, Zhenglin; Jiang, Qian; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu; Yan, Zhen
Article

SLAM-associated protein as a potential negative regulator in Trk signaling

Journal of Biological Chemistry, v. 280, (50), December 2005, p. 41744-41752
Lo, Kin Yip; Chin, Wing Hong; Ng, Yu Pong; Cheng, Albert W.; Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Article

The N-terminal cytokine binding domain of LIFR is required for CNTF binding and signaling

FEBS Letters, v. 579, (20), August 2005, p. 4317-4323
He, Wei; Gong, Ke; Smith, David K.; Ip, Nancy Yuk-Yu
Article

ANKRA Interacts With p35 and Is a Substrate for Cdk5/p35


Ng, Alberto K.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

ARMS Interacts With Alpha-Syntrophin: Implications for the Localization and Signaling of EphA4 at the Neuromuscular Synapse


Chen, Yu; Luo, Shuo; Lai, Kwok On; Arevalo, Juan C.; Froehner, Stanley C.; Adams, Marvin E.; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

ARMS Interacts With Alpha-Syntrophin: Implications for the Localization and Signaling of EphA4 at the Neuromuscular Synapse


Chen, Yu; Luo, Shuo; Lai, Kwok On; Arevalo, Juan C.; Froehner, Stanley C.; Adams, Marvin E.; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

Arms Interacts With Alpha-Syntrophin:Implications for EphA4 Signaling at the Neuromuscular Synapse


Chen, Yu; Luo, Shuo; Lai, Kwok On; Arvalo, J.C.; Froehner, S.C.; Adams, M.E.; Chao, M.V.; Ip, Nancy Yuk-Yu
Conference paper

CDK5 - An Emerging Key Player at Synapses


Ip, Nancy Yuk-Yu
Conference paper

Cyclin-Dependent Kinase 5 Regulates EphA4-Mediated Signaling and Post-Synaptic Specialization


Fu, Wing Yu; Sahin, Mustafa; Shi, Lei; Chen, Yu; Lai, Kwok On; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Conference paper

Cyclin-Dependent Kinase 5 Regulates the Development of Motor Axons and AChR Clustering at Neuromuscular Synapses


Fu, Kit Yu; Ip, Fanny C.F.; Cheung, Janet H.N.; Wang, Jerry Hsueh-ching; Yung, Wing Ho; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Axin in the Formation of Neuromuscular Junction


Lu, Cheney C.; Fu, Kit Yu; Ng, Yu Pong; Lin, Shengcai; Ip, Nancy Yuk-Yu
Conference paper

Identification of Anaphase Promoting Complex Subunit 2 Isoform as EphA4 Interacting Protein


Hung, Kwok Wang; Shen, Winnie Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of Critical Early Genes Involved in Nerve Growth Factor-Induced PC12 Differentiation


Xiao, Fang; Ng, Yu Pong; Tsim, Karl Wah Keung; Wise, Helen; Wong, Yung Hou; Ip, Nancy Yuk-Yu; Wu, Zhenguo
Conference paper

Identification of NRC-Interacting Factor 1 (NIF-1) as a p35-Interacting Protein


Zhao, Xiaosu; Li, Zhen; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of Trkb as a p35-Interacting Protein and a Cdk5 Substrate


Chin, Wing Hong; Ip, Nancy Yuk-Yu
Conference paper

NGF-Induced Neuronal Differentiation of PC12 Cells: Delineation of Signaling Molecules and Mapping of Pathways.


Leung, W.K.W.; Choi, Chi Yan; Ip, Nancy Yuk-Yu; Wu, Zhenguo; Wong, Yung Hou; Cheung, P.T.; Tsim, Karl Wah Keung
Conference paper

Overexpression of Galphaz Inhibits Muscle Differentiation


Mei, Hua; Wu, Zhenguo; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Conference paper

Pctaire1 Phosphorylates N-Ethylmaleimide Sensitive Fusion Protein and Regulates Constitutive Exocytosis in PC12 Cells


Liu, Yuxin; Cheng, Kai; Hung, Kwok Wang; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Postsynaptic Signaling of New Players at Synapses


Ip, Nancy Yuk-Yu
Conference paper

Role of Axin in Nerve Growth Factor-Stimulated Neurite Outgrowth


Ng, Yu Pong; Lin, Shengcai; Fu, Wing Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Role of Calmodulin-Dependent Kinase II in Nerve Growth Factor-Induced Differentiation of PC12 Cells.


Kam, Yuet Fong; Yung, Ying; Wu, Eddy H.T.; Ng, Yu Pong; Wu, Zhenguo; Tsim, Karl Wah Keung; Wise, Helen; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Conference paper

Screening for NMDA Receptor Antagonists Using Traditional Chinese Medicine


Ip, Fanny C.F.; An, Hui Jin; Chan, Agnes Wing Sze; Tong, Pui Sze; Hu, Sharry Y.; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Signaling Through the Ciliary Neurotrophic Factor Receptor Complex


Ip, Nancy Yuk-Yu
Conference paper
2004 19

Activity of Macrocyclic Jatrophane Diterpenes from Euphorbia kansui in a TrkA Fibroblast Survival Assay

Journal of Natural Products, v. 67, (9), September 2004, p. 1548-1551
Pan, Qin; Ip, Fanny Chun Fun; Ip, Nancy Yuk Yu; Zhu, Hua-Xu; Min, Zhi-Da
Article

Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription

Journal of Biological Chemistry, v. 279, (52), December 2004, p. 54438-54444
Li, Zhen; David, Gregory; Hung, Kwok Wang; Depinho, Ronald A.; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Cdk5: mediator of neuronal death and survival

Neuroscience Letters, v. 361, 1-3, May 2004, p. 47-51
Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Article

Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity

Proceedings of the National Academy of Sciences of the United States of America, v. 101, (17), April 2004, p. 6728-6733
Fu, Amy Kit Yu; Fu, Wing Yu; Ng, Alberto K. Y.; Chien, Winnie W. Y.; Ng, Yu Pong; Wang, Jerry H.; Ip, Nancy Yuk-Yu
Article

Identification of the Jak/Stat proteins as novel downstream targets of EphA4 signaling in muscle - Implications in the regulation of acetylcholinesterase expression

Journal of Biological Chemistry, v. 279, (14), April 2004, p. 13383-13392
Lai, Kwok On; Chen, Yu; Po, Hoi Man; Lok, Ka Chun; Gong, Ke; Ip, Nancy Yuk-Yu
Article

Melia toosendan regulates PC12 cell differentiation via the activation of protein kinase A and extracellular signal-regulated kinases

NeuroSignals, v. 13, (5), September 2004, p. 248-257
Yu, Jowie C.H.; Min, Zhi-Da; Ip, Nancy Yuk-Yu
Article

Use of Silicon-Based Oligonucleotide Chip in Authentication of Toxic Chinese Medicine

Herbal Medicine and Molecular Basis in Health and Disease Managemen / Edited by Lester Pack, Choon Nam Ong, Barry Halliwell. New York : Marcel Dekker, 2004, p. 754-770
Carles, Maria C.; Ip, Nancy Yuk-Yu
Book chapter

Association of Cyclin-Dependent Kinase 5 Activators With EphA4


Fu, Wing Yu; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Phosphorylation of STAT3 Regulates Its Transcriptional Activity in Neuregulin-ErbB Signaling


Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cyclin-Dependent Kinase 5 Phosphorylates STAT3 and Regulates Its Transcriptional Activity

Journal of Neurochemistry, v. 88, February 2004, p. 18
Fu, Kit Yu; Fu, Wing Yu; Ng, Alberto K.Y.; Chien, Winnie W.Y.; Ng, Yu Pong; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Identification of Endophilin B1 as a p35-Interacting Protein


Cheung, Anthony Y.H.; Fu, Wing Yu; Li, Zhen; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of mSds3, a Component of Transcriptional Repressor Complex, as a Novel p35-Interacting Protein


Fu, Kit Yu; Li, Zhen; David, G.; Hung, Kwok Wang; Depinho, R.A.; Ip, Nancy Yuk-Yu
Conference paper

Identification of N-Ethylmaleimide-Sensitive Fusion Protein as a pctaire1 Interacting Protein


Liu, Yuxin; Cheng, Kai; Hung, Kwok Wang; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Pctaire1 Regulates the Dendritic Development in Primary CNS Neurons


Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Postsynaptic Signaling of New Players at the Neuromuscular Synapse


Ip, Nancy Yuk-Yu
Conference paper

Regulation of STAT3 Activation by NGF During PC12 Neuronal Differentiation


Ng, Yu Pong; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Regulation of STAT3 Signaling in NGF-Induced Neuronal Differentiation


Ng, Yu Pong; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

The Role of Cyclin-Dependent Kinase 5 in Retinal Ganglion Cell Survival


Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Conference paper

Tyrosine Phosphorylation of Cyclin-Dependent Kinase 5 by Activated EphA4 Receptor


Fu, Wing Yu; Lai, Kwok On; Gong, Ke; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper
2003 15

Cdk5: A new player at synapses

NeuroSignals, v. 12, (4-5), 2003, p. 180-190
Cheng, K.; Ip, Nancy Yuk-Yu
Article

Central synapse and neuromuscular junction: same players, different roles

Trends in Genetics, v. 19, (7), July 2003, p. 395-402
Lai, Kwok On; Ip, Nancy Yuk-Yu
Article

Ephrin-B1 Reverse Signaling Activates JNK Through a Novel Mechanism that is Independent of Tyrosine Phosphorylation

Journal of Biological Chemistry, v. 278, (27), July 2003, p. 24767-24775
Xu, Zhen; Lai, Kwok On; Zhou, Hai-Meng; Lin, Sheng Cai; Ip, Nancy Yuk-Yu
Article

Leukemia Inhibitory Factor Receptor Signaling Negatively Modulates Nerve Growth Factor-induced Neurite Outgrowth in PC12 Cells and Sympathetic Neurons

Journal of Biological Chemistry, v. 278, (40), October 2003, p. 38731-38739
Ng, Yu Pong; He, Wei; Ip, Nancy Yuk-Yu
Article

Postsynaptic signaling of new players at the neuromuscular junction

Journal of Neurocytology, v. 32, 5-8, June 2003, p. 727-741
Lai, Kwok On; Ip, Nancy Yuk-Yu
Article

Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex

Journal of Biological Chemistry, v. 278, (26), June 2003, p. 23285-23294
Man, David; He, Wei; Sze, Kong Hung; Gong, Ke; Smith, David K.; Zhu, Guang; Ip, Nancy Yuk-Yu
Article

Modernization of traditional Chinese medicine in Hong Kong

Biotechnology in Hong Kong / Edited by Albert Wai-Kit Chan. New York : United States-China Intellectual Property Institute, 1999, p. 30-60
Ip, Nancy Yuk-Yu
Book chapter

Activation of EphA4 Receptor Triggers the JAK/STAT Signaling Pathway


Lai, Kwok On; Chen, Yu; Po, Hoi Man; Lok, Ka Chun; Gong, Ke; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Phosphorylates STAT3 and Regulates Its Transcriptional Activity


Fu, Kit Yu; Ng, Alberto K.Y.; Chien, Winnie W.Y.; Ng, Yu-Pong; Fu, Wing Yu; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Cdk5 During the Formation of the Neuromuscular Junction

Journal of Neurochemistry, v. 87, December 2003, p. 168-168
Fu, Kit Yu; Ip, Fanny C.F.; Cheung, Janet; Wang, Jerry Hsueh-ching; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Leukemia Inhibitory Factor Receptor Signaling Negatively Modulates NGF-Induced Neurite Outgrowth


Ng, Yu-Pong; He, Wei; Ip, Nancy Yuk-Yu
Conference paper

Pctaire-1 Regulates the Dendritic Development of Cultured Cortical Neurons


Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Pctaire-1 Regulates the Neurite Outgrowth and Dendritic Development in Primary Cortical Neurons


Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Slam-associated protein (SAP) interacts with TrkB-full length receptor

The 23rd Annual Scientific Conference of the Hong Kong Society of Neuroscience, 9-10 Dec
Lo, Kin Yip; Chin, Wing Hong; Ip, Nancy Y.
Conference paper

The Roles of G-Proteins in the Formation of Neuromuscular Junction and Myogenesis


Lok, Ka Chun; Fu, Wing Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper
2002 21

Expression of Cdk5 and its activators in NT2 cells during neuronal differentiation

Journal of Neurochemistry, v. 81, (3), May 2002, p. 646-654
Fu, Wing Yu; Wang, Jerry H.; Ip, Nancy Yuk-Yu
Article

Genotyping on a Complementary Metal Oxide Semiconductor Silicon Polymerase Chain Reaction Chip with Integrated DNA Microarray

Analytical Chemistry, v. 74, (13), July 2002, p. 3168-3173
Trau, Dieter Wilhelm; Lee, Ming Hung Thomas; Lao, Ieng Kin; Lenigk, Ralf; Hsing, I-Ming; Ip, Nancy Yuk-Yu; Carles, Maria C.; Sucher, Nikolaus J.
Article

Induction of Cdk5 activity in rat skeletal muscle after nerve injury

NeuroReport, v. 13, (2), February 2002, p. 243-247
Fu, Wing Yu; Fu, Amy Kit Yu; Lok, Ka Chun; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Integration of Signals from Receptor Tyrosine Kinases and G Protein-Coupled Receptors

NeuroSignals, v. 11, (1), January-February 2002, p. 5-19
Lowes, Vicki L.; Ip, Nancy Yuk-Yu; Wong, Ying Hou
Article

Letter to the Editor: Complete 1H, 15N and 13C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR)

Journal of Biomolecular NMR, v. 22, (1), January 2002, p. 95-96
Man, David; Xia, Youlin; Sze, Konghung; Smith, David Keith; He, Wei; Ip, Nancy Yuk-Yu; Zhu, Guang
Article

Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro

FEBS Letters, v. 514, (2-3), March 2002, p. 214-218
He, Wei; Gong, Ke; Zhu, Guang; Smith, David Keith; Ip, Nancy Yuk-Yu
Article

Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35

Journal of Biological Chemistry, v. 277, (35), August 2002, p. 31988-31993
Cheng, Kai; Li, Zhen; Fu, Wing-Yu; Wang, Jerry H; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

A Novel NGF-Like Activity Promotes the Survival of TrkA-Ectopically Expressed Fibroblast Cell Line During Serum Deprivation


Ip, Fanny C.F.; Tsang, Alex F.C.; Wong, Karan K.Y.; Pang, Tracy H.H.; Ip, Nancy Yuk-Yu
Conference paper

Aberrant Development of Neuromuscular Junction in Cdk5 Mutant Mice


Fu, Kit Yu; Ip, Fanny C.F.; Cheung, Janet H.N.; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Agrin-MuSK Signaling Mediates Presynaptic Differentiation


Xu, Xiaohua; Fu, Kit Yu; Yuan, Xiaobing; Jin, Ming; Wu, Chenping; Duan, Shumin; Poo, Mao Ming; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Is Involved in Modulation of ErbB2 Receptor Signaling


Fu, Wing Yu; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Cdk5: A New Player at the Neuromuscular Synapse


Ip, Nancy Yuk-Yu
Conference paper

Cdk5: A New Player at the Neuromuscular Synapse


Ip, Nancy Yuk-Yu
Conference paper

Characterization of the Interacting Domains Between the CNTF Receptor and Its Beta Receptor Components


Ip, Nancy Yuk-Yu
Conference paper

Involvement of G Protein Signaling Pathway at the Neuromuscular Junctions


Lok, Ka C.; Fu, Wing Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Leukemia Inhibitory Factor Receptor Inhibits NGF-Induced Neuronal Differentiation in PC12 Cells


Ng, Yu-Pong; He, Wei; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Nerve Growth Factor-Dependent Activation of C-Jun N-Terminal Kinase in PC12 Cells Is Mediated via Pertussis Toxin-Sensitive G Proteins


Tso, Ha; Yung, Ying; Yu, Jowie C.H.; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Conference paper

Pctaire1 Interacts With P35 and Is a Novel Substrate for Cdk5/P35


Cheng, Kai; Li, Jenny Z.; Fu, Wing Yu; Wang, Jerry Hsueh-ching; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Surface Characterization of DNA Microarray on Silicon Dioxide and Compatible Silicon Materials in the Immobilization Process

Materials Research Society Symposium - Proceedings, v. 711, 2002, p. 25-30
Xu, Wen; Li, Jiong; Xue, Mei; Carles, Maria; Trau, Dieter Wilhelm; Lenigk Ralf; Sucher, Nikolaus J.; Ip, Nancy Yuk-Yu; Chan, Mansun
Conference paper

The Phosphorylation of Pctaire1 by Cdk5 Regulates Its Activity


Cheng, Kai; Li, Jenny Z.; Fu, Wing Yu; Wang, Jerry Hsueh-ching; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Tyrosine Phosphorylation of Jak Kinases and Stat Proteins by Activated EphA4


Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper
2001 15

A reporter gene assay for the detection of phytoestrogens in traditional Chinese medicine

Phytotherapy Research, v. 15, (6), September 2001, p. 487-492
Miller-martini, David M; Chan, Robbie Y.K.; Ip, Nancy Yuk-Yu; Sheu, S.J.; Wong, Yung Hou
Article

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

Nature Neuroscience, v. 4, (4), April 2001, p. 374-381
Fu, Amy Kit Yu; Fu, Wing Yu; Cheung, Janet; Tsim, Karl Wah Keung; Ip, Fanny Chun Fun; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Article

Chips and Qi: Microcomponent-Based Analysis in Traditional Chinese Medicine

Fresenius Journal of Analytical Chemistry, v. 371, (2), September 2001, p. 190-194
Carles, Maria; Lee, Ming Hung Thomas; Moganti, Shanti; Lenigk, Ralf; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Hsing, I-Ming; Sucher, Nikolaus J.
Article

Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation

Journal of Biological Chemistry, v. 276, (2), May 2001, p. 17083-17091
Cheung, William M.W.; Chu, Apple H.; Chu, Patrick W.K.; Ip, Nancy Yuk-Yu
Article

Expression of Eph receptors in skeletal muscle and their localization at the neuromuscular junction

Molecular and Cellular Neuroscience, v. 17, (6), June 2001, p. 1034-1047
Lai, Kwok On; Ip, Fanny Chun Fun; Cheung, Janet; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Expression of the P2Y1 nucleotide receptor in chick muscle: Its functional role in the regulation of acetylcholinesterase and acetylcholine receptor

Journal of Neuroscience, v. 21, (23), December 2001, p. 9224-9234
Choi, Roy Chi Yan; Man, Menlisa L.S.; Ling, Karen K.Y.; Ip, Nancy Yuk-Yu; Simon, Joseph; Barnard, Eric A.; Tsim, Karl Wah Keung
Article

Overexpression of muscle specific kinase increases the transcription and aggregation of acetylcholine receptors in Xenopus embryos

Molecular Brain Research, v. 96, (1-2), November 2001, p. 21-29
Fu, Amy Kit Yu; Cheung, Janet; Smith, Frances Doneison; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Surface characterization of a silicon-chip-based DNA microarray

Langmuir, v. 17, (8), April 2001, p. 2497-2501
Lenigk, Ralf; Carles, Marias; Ip, Nancy Yuk-Yu; Sucher, Nikolaus J.
Article

The expression profiles of neurotrophins and their receptors in rat and chicken tissues during development

Neuroscience Letters, v. 301, (2), March 2001, p. 107-110
Ip, Fanny Chun Fun; Cheung, Janet; Ip, Nancy Yuk-Yu
Article

A Study of the Spectral Sensitivity of Photodiode From a Standard CMOS Process for DNA Detection

International Symposium on IC Technology, Systems and Applications, v. 9, 2001, p. 303-306
Xue, Mei; Xu, Wen; Lu, Gang; Carles, Maria; Sucher, Nikolaus J.; Ip, Nancy Yuk-Yu; Ko, Ping Keung; Chan, Mansun
Conference paper

Characterization of Immobilized DNA Probes on the Surface of Silicon Compatible Materials

Proceedings of the IEEE Hong Kong Electron Devices Meeting, 2001, p. 60-63
Wen, Xiaogang; Mei, X.; Lenigk, Ralf; Carles, Marias; Sucher, Nikolaus J.; Ip, Nancy Yuk-Yu; Chan, Man Sun
Conference paper

Integrated DNA Detection System on Silicon Substrate With Photodiodes

International Symposium on IC Technology, Systems and Applications, v. 9, 2001, p. 299-302
Xu, Wen; Xue, Mei; Lenigk, Ralf; Carles, Marias; Sucher, Nikolaus J.; Ip, Nancy Yuk-Yu; Chan, Mansun
Conference paper

Integrated Photodiode DNA Identification System for Genetic Chip Applications


Xue, Mei; Xu, Wen; Lenigk, Ralf; Carles, Maria; Sucher, Nikolaus J.; Ip, Nancy Yuk-Yu; Chan, Mansun
Conference paper

Leukemia Inhibitory Factor Receptor Signaling Has Regulatory Inhibitory Effect on NGF-Induced Neuronal Differentiation of PC12 Cells


He, Wei; Ng, Yu-Pong; Ip, Nancy Yuk-Yu
Conference paper

Optical Response of Photodiode in Integrated DNA Detection System

Proceedings of the IEEE Hong Kong Electron Devices Meeting, 2001, p. 25-28
Xue, Mei; Xu, Wen; Lu, Gang; Ip, Nancy Yuk-Yu; Ko, Ping Keung; Chan, Mansun
Conference paper
2000 13

A J-multiplied HMQC (MJ-HMQC) experiment for measuring 3JHNHα coupling constants

Journal of Magnetic Resonance, v. 146, (1), September 2000, p. 228-231
Xia, Youlin; Kong, Xiangming; Ip, Nancy Yuk-yu; Zhu, Guang
Article

Altered expression of tissue-type plasminogen activator and type 1 inhibitor in astrocytes of mouse cortex following scratch injury in culture

Neuroscience Letters, v. 285, (2), May 2000, p. 143-146
Tang, Huibin; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Article

Biotechnology finds its way to Hong Kong

International Journal of Biotechnology, v. 2, (4), 2000, p. 355-363
Kung, Shain-Dow; Wong, Joseph Tin Yum; Ip, Nancy Yuk-Yu
Article

Cloning and characterization of muscle-specific kinase in chicken

Molecular and Cellular Neuroscience, v. 16, (5), November 2000, p. 661-673
Ip, Fanny Chun Fun; Glass, David G.; Gies, David R.; Cheung, Janet; Lai, Kwok On; Fu, Amy Kit Yu; Yancopoulos, George D.; Ip, Nancy Yuk-Yu
Article

Developmental and tissue-specific expression of DEAD box protein p72

NeuroReport, v. 11, (3), February 2000, p. 457-462
Ip, Fanny Chun Fun; Chung, Sarah S.K.; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Article

Expression of retinoid receptors during the retinoic acid-induced neuronal differentiation of human embryonal carcinoma cells

Journal of Neurochemistry, v. 75, (1), July 2000, p. 34-40
Cheung, William M.W.; Chu, Patrick W.K.; Lung, Chuek H.; Ip, Nancy Yuk-Yu
Article

Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells

FEBS Letters, v. 486, (3), December 2000, p. 291-296
Cheung, William M.W.; Hui, Wing S.; Chu, Patrick W.K.; Chiu, Siuwai; Ip, Nancy Yuk-Yu
Article

Identification and characterization of differentially expressed genes in denervated muscle

Molecular and Cellular Neuroscience, v. 16, (2), August 2000, p. 127-140
Tang, Huibin; Cheung, William M.W.; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

IL-6 enhanced the retinoic acid-induced differentiation of human acute promyelocytic leukemia cells

Cancer Letters, v. 148, (2), February 2000, p. 207-213
Xie, Ping; Chan, Frances S.L.; Ip, Nancy Yuk-Yu; Leung, Mun-Fai
Article

Induction of TrkA expression by differentiation inducers in human myeloid leukemia KG-1 cells

Leukemia & Lymphoma, v. 36, (5-6), February 2000, p. 595-601
Xie, Ping; Chan, Frances; Ip, Nancy Yuk-Yu; Leung, Mun-Fai
Article

Nerve growth factor potentiated the sodium butyrate- and PMA-induced megakaryocytic differentiation of K562 leukemia cells

Leukemia Research, v. 24, (9), September 2000, p. 751-759
Xie, Ping; Chan, Frances S.L.; Ip, Nancy Yuk-Yu; Leung, Mun-Fai
Article

Precise Temperature Control of Microfluidic Chamber for Gas and Liquid Phase Reactions

Sensors and Actuators A: Physical, v. 84, (1-2), August 2000, p. 11-17
Lao, Ieng Kin; Lee, Ming Hung Thomas; Hsing, I-Ming; Ip, Nancy Yuk-Yu
Article

Synergistic effects of muscarinic agonists and secretin or vasoactive intestinal peptide on the regulation of tyrosine hydroxylase activity in sympathetic neurons

Journal of Neurobiology, v. 42, (1), January 2000, p. 14-21
Ip, Nancy Yuk-Yu; Zigmond, R.E.
Article
1999 7

A cysteine-rich form of Xenopus neuregulin induces the expression of acetylcholine receptors in cultured myotubes

Molecular and Cellular Neuroscience, v. 13, (6), June 1999, p. 415-429
Yang, Jiefei; Zhou, Hong; Choi, Roy Chi Yan; Ip, Nancy Yuk-Yu; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung
Article

Identification and characterization of splice variants of ephrin-A3 and ephrin-A5

FEBS Letters, v. 458, (2), September 1999, p. 265-269
Lai, Kwok On; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Identification of genes induced by neuregulin in cultured myotubes

Molecular and Cellular Neuroscience, v. 14, (3), September 1999, p. 241-253
Fu, Amy Kit Yu; Cheung, William M.W.; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Induction of gp130 and LIF by differentiation inducers in human myeloid leukemia K562 cells

Leukemia Research, v. 23, (12), December 1999, p. 1113-1119
Xie, Ping; Chan, Frances S.L.; Ip, Nancy Yuk-Yu; Leung, M.F.
Article

Production of human CNS neurons from embryonal carcinoma cells using a cell aggregation method

BioTechniques, v. 26, (5), May 1999, p. 946-954
Cheung, William M.W.; Fu, Wing Yu; Hui, Wing S.; Ip, Nancy Yuk-Yu
Article

Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development

European Journal of Neuroscience, v. 11, (2), February 1999, p. 373-382
Fu, Amy Kit Yu; Smith, Frances D.; Zhou, Hong; Chu, Apple H.; Tsim, Karl Wah Keung; Peng, Benjamin H.; Ip, Nancy Yuk-Yu
Article

The Cloning and Expression of Xenopus Laevis MuSK That May Be Involved in Synaptogenesis


Smith, F.D.; Chu, A.H.; Zhou, H.; Fu, Kit Yu; Tsim, K.W.K.; Peng, H.B.; Ip, Nancy Yuk-Yu
Conference paper
1998 8

A Molecular Biology Network for Asia and the Pacific Rim

Science, v. 280, (5370), June 1998, p. 1708
Ip, Nancy Yuk-Yu; Shahi, Gurinder
Article

Cloning and expression of a novel neurotrophin, NT-7, from carp

Molecular and Cellular Neuroscience, v. 11, (1-2), May 1998, p. 64-76
Lai, Kwok On; Fu, Wing Yu; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Cloning of cDNAs encoding Xenopus neuregulin: expression in myotomal muscle during embryo development

Molecular Brain Research, v. 58, (1-2), July 1998, p. 69-73
Yang, Jiefei; Zhou, Hong; Pun, San; Ip, Nancy Yuk-Yu; Peng, H. Benjamin; Tsim, Karl Wah Keung
Article

Expression of BDNF and trkB as a function of age and cognitive performance

Brain Research, v. 812, (1-2), November 1998, p. 200-208
Croll, Susan D.; Ip, Nancy Yuk-Yu; Lindsay, Ronald M.; Wiegand, Stanley J.
Article

Induction of NG108-15 cells differentiation by human bone marrow stromal cells

NeuroReport, v. 9, (7), May 1998, p. 1365-1369
Ho, Siu Hong; So, Lac Hue; Lai, Kwok On; Ip, Nancy Yuk-Yu; Leung, Mun Fai
Article

Interaction of neurotrophins and retinoic acid in neuronal differentiation

Molecules and Cells, v. 8, (4), August 1998, p. 496-502
Cheung, William M.W.; Ip, Nancy Yuk-Yu
Article

The neurotrophins and neuropoietic cytokines: Two families of growth factors acting on neural and hematopoietic cells

Annals of the New York Academy of Sciences, v. 840, (1), May 1998, p. 97-106
Ip, Nancy Yuk-Yu
Article

Regulation of Muscle-Specific Kinase (MuSK) During the Formation of Neuromuscular Junction


Ip, F.C.F.; Fu, Kit Yu; Cheung, J.; Ip, Nancy Yuk-Yu
Conference paper
1997 10

Agrin-deficient myotube retains its acetylcholine receptor aggregation ability when challenged with agrin

Journal of Neurochemistry, v. 69, (6), December 1997, p. 2555-2563
Pun, San; Ng, Yu Pong; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung
Article

Chick muscle expresses various ARIA isoforms: Regulation during development, denervation, and regeneration

Molecular and Cellular Neuroscience, v. 9, (2), 1997, p. 132-143
Ng, Yu Pong; Pun, San; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung
Article

Identification of candidate genes induced by retinoic acid in embryonal carcinoma cells

Journal of Neurochemistry, v. 68, (5), May 1997, p. 1882-1888
Cheung, William M.W.; Chu, Apple H.; Ip, Nancy Yuk-Yu
Article

Induction of TrkA receptor by retinoic acid in leukaemia cell lines

NeuroReport, v. 8, (5), March 1997, p. 1067-1070
Xie, Ping; Cheung, William M.W.; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu; Leung, Mun-Fai
Article

Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron-muscle co-cultures

NeuroReport, v. 8, (18), December 1997, p. 3895-3900
Fu, Amy Kit Yu; Ip, Fanny Chun Fai; Lai, Kwok On; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Article

The EGF-like domain of chick acetylcholine receptor-inducing activity (ARIA) contains its full biological activity

FEBS Letters, v. 403, (2), February 1997, p. 163-167
Yang, Jiefei; Ng, Yu Pong; Pun, San; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung
Article

Trauma-induced striatal CNTF and BDNF mRNA in hemiparkinsonian rats

NeuroReport, v. 8, (2), January 1997, p. 507-511
Plunkett, Robert J.; Ip, Nancy Yuk-Yu; Asada, Hideo; Friedman, Beth; Pan, Li; Kaseloo, Paul A.; Parfitt, Margaret M.
Article

Cloning and Expression of Xenopus MuSK


Chu, A.H.; Smith, F.D.; Ip, F.C.F.; Fu, Kit Yu; Tsim, K.W.K.; Peng, H.B.; Ip, Nancy Yuk-Yu
Conference paper

Identification of Candidate Genes Involved in ARIA Signaling Pathway During the Formation of Neuromuscular Junction Using RAP-PCR


Fu, Kit Yu; Cheung, W.M.W.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Identification of Candidate Genes Involved in the ARIA Signaling Pathway During Synapse Formation


Fu, Kit Yu; Cheung, W.M.W.; Ip, Nancy Yuk-Yu
Conference paper
1996 9

Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury

Journal of Neurochemistry, v. 67, (4), October 1996, p. 1607-1612
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Article

Induction of trk receptors by retinoic acid in a human embryonal carcinoma cell line

NeuroReport, v. 7, (6), April 1996, p. 1204-1208
Cheung, William M.W.; Chu, Apple H.; Leung, Mun-Fai; Ip, Nancy Yuk-Yu
Article

Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras

Journal of Neuroscience Research, v. 46, (5), December 1996, p. 618-629
Lai, Kwok On; Glass, David J.; Geis, David; Yancopoulos, George D.; Ip, Nancy Yuk-Yu
Article

The neurotrophins and CNTF: Two families of collaborative neurotrophic factors

Annual Review of Neuroscience, v. 19, March 1996, p. 491-515
Ip, Nancy Yuk-yu; Yancopoulos, George D.
Article

Agrin Induces Phosphorylation of Muscle-Specific Kinase (MuSK) in Myotube Culture


Fu, Kit Yu; Chan, K.M.; Ip, F.C.F.; Valenzuela, D.M.; Glass, D. J. '; Yancopoulos, G.D.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Developmental Expression and Upregulation of Muscle-Specific Kinase (MuSK) in Denervated Skeletal Muscle of the Chick and Rat


Ip, F.C.F.; Fu, Kit Yu; Tsim, K.W.K.; Cheung, J.; Valenzuela, D.M.; Glass, D.J.; Yancopoulos, G.D.; Ip, Nancy Yuk-Yu
Conference paper

Expression of Muscle-Specific Kinase at the Neuromuscular Junction


Ip, F.C.F.; Fu, Kit Yu; Chan, K.M.; Tsim, K.W.K.; Valenzuela, D.M.; Glass, D.J.; Yancopoulos, G.D.; Ip, Nancy Yuk-Yu
Conference paper

Muscle-Specific Kinase (MuSK) Mediates Nerve-Induced Tyrosine Phosphorylation and Aggregation of Acetylcholine Receptors in Neuron-Muscle Co-Cultures.


Fu, Kit Yu; Ip, F.C.F.; Glass, D.J.; Valenzuela, D.M.; Yancopoulos, G.D.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Regulation of Muscle-Specific Kinase (MuSK) During Development and After Nerve Injury


Ip, F.C.F.; Fu, Kit Yu; Lai,K-O; Cheung, J.; Glass, D.J.; Yancopoulos, G.D.; Ip, Nancy Yuk-Yu
Conference paper
1995 15

BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons

Journal of Neuroscience, v. 15, (2), February 1995, p. 1044-1056
Friedman, Beth; Kleinfeld, David; Ip, Nancy Yuk-Yu; Verge, Valerie M.K.; Moulton, Ronald; Boland, Patricia; Zlotchenko, Elizabeth; Lindsay, Ronald M.; Liu, Liming
Article

Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines

Journal of Biological Chemistry, v. 270, (1), 1995, p. 313-318
Wong, Vivien; Pearsall, Danise; Arriaga, Ruth; Ip, Nancy Yuk-Yu; Stahl, Neil; Lindsay, Ronald M.
Article

Cloning of the α component of the chick ciliary neurotrophic factor receptor: Developmental expression and down-regulation in denervated skeletal muscle

Journal of Neurochemistry, v. 65, (6), December 1995, p. 2393-2400
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Article

Genomic organization and chromosomal localization of the human and mouse genes encoding the α receptor component for ciliary neurotrophic factor

Genomics, v. 25, (1), Jannuary 1995, p. 157-163
Valenzuela, David M.; Rojas, Eduardo; Le beau, Michelle M.; Espinosa III, Rafael; Brannan, Camilynn I.; Mcclain, Joyce; Masiakowski, Piotr; Ip, Nancy Yuk-Yu; Copeland, Neal G.; Jenkins, Nancy A.; Yancopoulos, George D.
Article

Identification of full-length and truncated forms of Ehk-3, a novel member of the Eph receptor tyrosine kinase family

Oncogene, v. 10, (8), April 1995, p. 1573-1580
Valenzuela, D.M.; Rojas, E.; Griffiths, J.A.; Compton, D.L.; Gisser, M.; Ip, Nancy Yuk-Yu; Goldfarb, M.; Yancopoulos, G.D.
Article

Identification of mammalian noggin and its expression in the adult nervous system

Journal of Neuroscience, v. 15, (9), September 1995, p. 6077-6084
Valenzuela, David M.; Economides, Aris N.; Rojas, Eduardo; Lamb, Teresa M.; Nunez, Lorna; Jones, Pam; Ip, Nancy Yuk-Yu; Espinosa III, R.; Brannan, C.I.; Gilbert, David J.; Copeland, Neal G.; Jenkins, Nancy A.; Le beau, Michelle M.; Harland, Richard M.; Yancopoulos, George D.
Article

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

Cell, v. 83, (2), October 1995, p. 313-322
Dechiara, Thomas M.; Vejsada, Richard; Poueymirou, William T.; Acheson, Ann; Suri, Chitra; Conover, Joanne C.; Friedman, Beth; Mcclain, Joyce; Pan, Li; Stahl, Neil; Ip, Nancy Yuk-Yu; Kato, Ann; Yancopoulos, George D.
Article

Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4

Nature, v. 375, (6528), May 1995, p. 235-238
Conover, J.C.; Erickson, J.T.; Katz, D.M.; Bianchi, L.M.; Poueymirou, W.T.; Mcclain, J.; Pan, L.; Helgren, M.; Ip, Nancy Yuk-Yu; Boland, P.; Friedman, B.; Wiegsand, S.; Vejsada, R.; Kato, A.C.; Dechiara, T.M.; Yancopoulos, G.D.
Article

Neurotrophin-3 augments steroid secretion by hamster ovarian follicles in vitro

Zoological Science, v. 12, (4), August 1995, p. 499-502
Waraksa, Julie A.; Lindsay, Ronald M.; Ip, Nancy Yuk-Yu; Hutz, Reinhold J.
Article

Time course of ciliary neurotrophic factor mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum

Journal of Neuroscience Research, v. 40, (1), January 1995, p. 22-30
Asada, H.; Ip, Nancy Yuk-Yu; Pan, L.; Razack, N.; Parfitt, M.M.; Plunkett, R.J.
Article

Neurotrophic factors and their receptors

Gene Expression in The Central Nervous System / Edited by Albert C.H. Yu, Lawrence F. Eng, Uel J. Mcmahan, Howard Schulman, Eric M. Shooter, Alfreda Stadlin. Amsterdam, The Netherlands : Elsevier, 1995, p. 189-195, Ch. 17. Book series: Progress in Brain Research, v. 105
Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Book chapter

Developmental Expression and Downregulation of the ? Component of Chick CNTF in Denervated Skeletal Muscle


Ip, F.C.F.; Fu, Kit Yu; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Expression of Neurotrophic Factors and Their Receptors, and Presynaptic Terminal Proteins During the Formation of the Neuromuscular Junctions


Chan, K.M.; Smith, F.D.; Fu, Kit Yu; Tsim, K.W.K.; Ip, F.C.F.; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Neurotrophic Factors During Synaptogenesis in a Neuron-Muscle Co-Culture System


Fu, Kit Yu; Chan, K.M.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Neurotrophic Factors on Synapse Formation in a Neuron-Muscle Co-Culture System


Fu, Kit Yu; Lai,K-O; Ip, F.C.F.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper
1994 11

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components

Science, v. 263, (5143), January 1994, p. 92-95
Stahl, N.; Boulton, T.G.; Farruggella, T.; Ip, Nancy Yuk-Yu; Davis, S.; Witthuhn, B.A.; Quelle, F.W.; Silvennoinen, O.; Barbieri, G.; Pellegrini, S.; Ihle, J.N.; Yancopoulos, G.D.
Article

CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons

Neuron, v. 13, (2), August 1994, p. 443-455
Ip, Nancy Yuk-Yu; Boulton, Teri G.; Li, Yanping; Verdi, Joesph M.; Birren, Susan J.; Anderson, David J.; Yancopoulos, George D.
Article

Expression and functionality of the trkA proto-oncogene product/NGF receptor in undifferentiated hematopoietic cells

Blood, v. 83, (6), March 1994, p. 1479-1485
Chevalier, Sylvie; Praloran, Vicent; Smith, Carthage; Grogan, Donal Mac; Ip, Nancy Yuk-Yu; Yancopoulos, George D.; Brachet, Philippe; Pouplard, Annick; Gascan, Hugues
Article

In situ hybridization of trkB and trkC receptor mRNA in rat forebrain and association with high-affinity binding of [125I]BDNF, [125I]NT-4/5 and [125I]NT-3

European Journal of Neuroscience, v. 6, (9), September 1994, p. 1389-1405
Altar, C. Anthony; Siuciak, Judith A.; Wright, Paul; Ip, Nancy Yuk-Yu; Lindsay, Ronald M.; Wiegand, Stanley J.
Article

Leukemia inhibitory factor and neurotrophins support overlapping populations of rat nodose sensory neurons in culture

Developmental Biology, v. 161, (2), February 1994, p. 338-344
Thaler, Catherine D.; Suhr, Leigh; Ip, Nancy Yuk-Yu; Katz, David M.
Article

Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes

European Journal of Neuroscience, v. 6, (5), May 1994, p. 693-705
Rudge, John S.; Li, Yanping; Pasnikowski, Elizabeth M.; Mattsson, Karen; Pan, Li; Yancopoulos, George D.; Wiegand, Stanley J.; Lindsay, Ronald M.; Ip, Nancy Yuk-Yu
Article

Neurotrophic factor receptors: Just like other growth factor and cytokine receptors?

Current Opinion in Neurobiology, v. 4, (3), June 1994, p. 400-405
Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Article

Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT- 4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon

Journal of Neuroscience, v. 14, (1), January 1994, p. 335-347
Hyman, Carolyn; Juhasz, Melissa; Jackson, Carl; Wright, Paul; Ip, Nancy Yuk-Yu; Lindsay, Ronald M.
Article

Retrograde axonal transport of LIF is increased by peripheral nerve injury: Correlation with increased LIF expression in distal nerve

Neuron, v. 12, (1), January 1994, p. 191-204
Curtis, Rory; Scherer, Steven S.; Somogyi, Robert; Adryan, Krystyna M.; Ip, Nancy Yuk-Yu; Zhu, Yuan; Lindsay, Ronald M.; Distefano, Peter S.
Article

The tails of two proteins: the scrapie prion protein and the ciliary neurotrophic factor receptor

Brazilian Journal of Medical and Biological Research, v. 27, (2), February 1994, p. 297-301
Stahl, N; Boulton, T.G.; Ip, Nancy Yuk-Yu; Davis, S.; Yancopoulos, G.D.
Article

Neurotrophic Factors and Their Receptors

Annals of Neurology, v. 35, (S), May 1994, p. S13-S16
Ip, Nancy Yuk-Yu; Yancopouloš, George D.
Conference paper
1993 14

Alternative forms of rat TrkC with different functional capabilities

Neuron, v. 10, (5), May 1993, p. 963-974
Valenzuela, David M.; Maisonpierre, Peter C.; Glass, David J.; Rojas, Eduardo; Nunez, Lorna; Kong, Yuan; Gies, David R.; Stitt, Tervor N.; Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Article

Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3

Journal of Neuroscience, v. 13, (12), December 1993, p. 5263-5276
Sofroniew, M.V.; Cooper, J.D.; Svendsen, C.N.; Crossman, P.; Ip, Nancy Yuk-Yu; Lindsay, R.M.; Zafra, F.; Lindholm, D.
Article

Ciliary neurotrophic factor maintains the pluripotentiality of embryonic stem cells

Development, v. 119, (3), 1993, p. 559-565
Conover, J.C.; Ip, Nancy Yuk-Yu; Poueymirou, W.T.; Bates, B.; Goldfarb, M.P.; Dechiara, T.M.; Yancopoulos, G.D.
Article

Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component

Journal of Biological Chemistry, v. 268, (11), April 1993, p. 7628-7631
Stahl, Neil; Davis, Samuel; Wong, Vivien; Taga, Tetsuya; Kishimoto, Tadmitsu; Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Article

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

Journal of Neuroscience, v. 13, (8), August 1993, p. 3394-3405
Ip, Nancy Yuk-Yu; Li, Yanping; Yancopoulos, George D.; Lindsay, Ronald M.
Article

Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain

European Journal of Neuroscience, v. 5, (1), January 1993, p. 25-33
Ip, Nancy Yuk-Yu; Wiegand, Stanley J.; Morse, Joanne; Rudge, John S.
Article

LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

Science, v. 260, (5115), June 1993, p. 1805-1808
Davis, S.; Aldrich, T.H.; Stahl, N.; Pan, L.; Taga, T.; Kishimoto, T.; Ip, Nancy Yuk-Yu; Yancopoulos, G.D.
Article

Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion

Development, v. 117, (4), 1993, p. 1345-1353
Ibanez, Carlos F.; Ernfors, Patrik; Timmusk, Tonis; Ip, Nancy Yuk-Yu; Arenas, Ernest; Yancopoulos, George D.; Persson, Hakan
Article

Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF

Nature, v. 363, (6427), May 1993, p. 350-353
Lohof, Ann M.; Ip, Nancy Yuk-Yu; Poo, Mu-ming
Article

Receptors and signaling pathways of ciliary neurotrophic factor and the neurotrophins

Seminars in Neuroscience, v. 5, (4), August 1993, p. 249-257
Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Article

Released form of CNTF receptor α component as a soluble mediator of CNTF responses

Science, v. 259, (510)2, March 1993, p. 1736-1739
Davis, S.; Aldrich, T.H.; Ip, Nancy Yuk-Yu; Stahl, N.; Scherer, S.; Farruggella, T.; Distefano, P.S.; Curtis, R.; Panayotatos, N.; Gascan, H.; Chevalier, S.; Yancopoulos, G.D.
Article

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

Neuron, v. 10, (2), February 1993, p. 137-149
Ip, Nancy Yuk-Yu; Stitt, Trevor N.; Tapley, Peter; Klein, Rudiger; Glass, David J.; Fandl, James; Greene, Lloyd A.; Barbacid, Mariano; Yancopoulos, George D.
Article

The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons

European Journal of Neuroscience, v. 5, (5), May 1993, p. 466-474
Wong, Vivien; Arriaga, Ruth; Ip, Nancy Yuk-Yu; Lindsay, Ronald M.
Article

The α component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

Neuron, v. 10, (1), January 1993, p. 89-102
Ip, Nancy Yuk-Yu; Mcclain, Joyce; Barrezueta, Nestor X.; Aldrich, Thomas H.; Pan, Li; Li, Yanping; Wiegand, Stanley J.; Friedman, Beth; Davis, Samuel; Yancopoulos, George D.
Article
1992 7

Ciliary neurotrophic factor and its receptor complex

Progress in Growth Factor Research, v. 4, (2), 1992, p. 139-155
Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Article

CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

Cell, v 69, (7), June 1992, p. 1121-1132
Ip, Nancy Yuk-Yu; Nye, Steven H.; Boulton, Tert G.; Davis, Samuel; Taga, Tetsuya; Li, Yanping; Birren, Susan J.; Yasukawa, Kiyoshi; Kishimoto, Tadamitus; Anderson, David J.; Stahl, Neil; Yancopoulos, George D.
Article

Expression of Ciliary Neurotrophic Factor and the Neurotrophins – Nerve Growth Factor, Brain‐Derived Neurotrophic Factor and Neurotrophin 3—in Cultured Rat Hippocampal Astrocytes

European Journal of Neuroscience, v. 4, (6), June 1992
Rudge, John S.; Alderson, Ralph F.; Pasnikowski, Elizabeth; Mcclain, Joyce; Ip, Nancy Yuk-Yu; Lindsay, Ronald M.
Article

K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses

Molecular Biology of the Cell, v. 3, (6), June 1992, p. 677-686
Nye, Steven H.; Squinto, Stephen P.; Glass, David J.; Stitt, Trevor N.; Hantzopoulos, Petros; Macchi, Mary J.; Lindsay, Nancy S.; Ip, Nancy Yuk-Yu; Yancopoulos, George D.
Article

Mammalian neurotrophin-4: Structure, chromosomal localization, tissue distribution, and receptor specificity

Proceedings of the National Academy of Sciences of the United States of America, v. 89, (7), 1992, p. 3060-3064
Ip, Nancy Yuk-Yu; Ibanez, Carlos F.; Nye, Steven H.; Mcclain, Joyce; Jones, Pamela F.; Gies, David R.; Belluscio, Leonardo; Le beau, Michelle M.; Espinosa III, R.; Squinto, Stephen P.; Persson, Hakan; Yancopoulos, George D.
Article

Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo

Neuron, v. 9, (2), August 1992, p. 295-305
Friedman, Beth; Scherer, Steven S.; Rudge, John S.; Helgren, Maureen; Morrisey, Donna; Mcclain, Joyce; Wang, Da-yuan; Wiegand, Stanley J.; Furth, Mark E.; Lindsay, Ronald M.; Ip, Nancy Yuk-Yu
Article

Cloning and Analysis of Neurotrophic Factor Receptors Using Function- Based Strategies

The Cell Surface, v. 57, 1992, p. 53-62
Glass, David J.; Gies, David R.; Stitt, Trevor N.; Davis, Samuel; Hantzopoulos, Petros A.; Ip, Nancy Yuk-Yu; Goldfarb, Mitchell P.; Yancopouloš, George D.
Conference paper
1991 5

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures

Journal of Neuroscience, v. 11, (10), October 1991, p. 3124-3134
Ip, Nancy Yuk-Yu; Li, Yanping; Van de stadt, Ingrid; Panayotatos, Nikos; Alderson, Ralph F.; Lindsay, Ronald M.
Article

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

Cell, v. 65, (4), May 1991, p. 663-675
Boulton, Teri G.; Nye, Steven H.; Robbins, David J.; Ip, Nancy Yuk-Yu; Radziejewska, Elizabeth; Morgenbesser, Sharon D.; Depinho, Ronald A.; Panayotatos, Nikos; Cobb, Melanie H.; Yancopoulos, George D.
Article

Human and rat brain-derived neurotrophic factor and neurotrophin-3: Gene structures, distributions, and chromosomal localizations

Genomics, v. 10, (3), July 1991, p. 558-568
Maisonpierre, Peter C.; Le beau, Michelle M.; Espinosa III, R.; Ip, Nancy Yuk-Yu; Belluscio, Leonardo; De la monte, Suzanne M.; Squinto, Stephen; Furth, Mark E.; Yancopoulos, George D.
Article

The Neurotrophin Family of NGF-Related Neurotrophic Factors

Restorative Neurology and Neuroscience, v. 2, (4-6), 1991, p. 211-220
Lindsay, Ronald M.; Alderson, Ralph F.; Friedman, Beth; Hyman, Carolyn; Ip, Nancy Yuk-Yu; Furth, Mark E.; Maisonpierre, Peter C.; Squinto, Stephen P.; Yancopouloš, George D.
Article

The neurotrophins and CTNF: Specificity of action towards PNS and CNS neurons

Journal de Physiologie, v. 85, (3), 1991, p. 123-130
Ip, Nancy Yuk-Yu; Maisonpierre, P.; Alderson, R.; Friedman, B.; Furth, M.E.; Panayotatos, N.; Squinto, S.; Yancopoulos, G.D.; Lindsay, R.M.
Article
1990 3

DNA linkage analysis and studies of the androgen receptor gene in a large kindred with complete androgen insensitivity

American Journal of Medical Genetics, v. 36, (1), May 1990, p. 104-108
Imperato-Mcginley, Julianne; Ip, Nancy Yuk-Yu; Gautier, Teofilo; Neuweiler, John; Gruenspan, Harry; Liao, Shutsung; Chang, Chawnshang; Balazs, Ivan
Article

Neurotrophin-3: A neurotrophic factor related to NGF and BDNF

Science, v. 247, (4949), March 1990, p. 1446-1451
Maisonpierre, P.C.; Belluscio, L.; Squinto, S.; Ip, Nancy Yuk-Yu; Furth, M.E.; Lindsay, R.M.; Yancopoulos, G.D.
Article

Neurotrophic Factors, Their Receptors, and the Signal Transduction Pathways They Activate

The Brain, v. 55, 1990, p. 371-379
Yancopouloš, George D.; Maisonpierre, P.C.; Ip, Nancy Yuk-Yu; Aldrich, Thomas H.; Belluscio, Leonardo; Boulton, Teri G.; Cobb, Melanie H.; Squinto, Stephen P.; Furth, Mark E.
Conference paper
1989 3

Activation of ganglionic tyrosine hydroxylase by peptides of the secretin-glucagon family: Structure-function studies

Neuroscience, v. 31, (1), 1989, p. 159-167
Schwarzchild, M.A.; Vale, W.; Corigliano-urphy, A.C.; Pisano, J.J.; Ip, Nancy Yuk-Yu; Zigmond, R.E.
Article

Discovery of a novel multilocus DNA polymorphism [DNF24]

Nucleic Acids Research, v. 17, (11), June 1989, p. 4427
Ip, Nancy Yuk-Yu; Nicholas, Leric; Baum, Howard; Balazs, Ivan
Article

Identification and Characterization of a hypervariable region [D18S27] on chromosome 18

Nucleic Acids Research, v. 17, (20), October 1989, p. 8404
Ip, Nancy Yuk-Yu; Van de stadt, I.; Loewy, Z.; Leary, S.; Grzeschik, K.; Balazs, I.
Article
1986 1

Cholinergic and Peptidergic Regulation of Ganglionic Tyrosine Hydroxylase Activity

Dynamics of Cholinergic Function / Edited by Israel Hanin. Springer, 1986, p. 1039-1045
Zigmond, R.E.; Ip, Nancy Yuk-Yu
Book chapter
1985 2

Long-term regulation of tyrosine hydroxylase activity in the superior cervical ganglion in organ culture: Effects of nerve stimulation and dexamethasone

Brain Research, . 338, (1), July 1985, p. 61-70
Ip, Nancy Yuk-Yu; Zigmond, Richard E.
Article

Regulation of the concentration of adenosine 3',5'-cyclic monophosphate and the activity of tyrosine hydroxylase in the rat superior cervical ganglion by three neuropeptides of the secretin family

Journal of Neuroscience, v. 5, (7), July 1985, p. 1947-1954
Ip, Nancy Yuk-Yu; Baldwin, C.; Zigmond, R.E.
Article
1984 3

Acute stimulation of ganglionic tyrosine hydroxylase activity by secretin, VIP and PHI

Peptides, v. 5, (2), March 1984, p. 309-312
Ip, Nancy Yuk-Yu; Baldwin, Claire; Zigmond, Richard E.
Article

Pattern of presynaptic nerve activity can determine the type of neurotransmitter regulating a postsynaptic event

Nature, v. 311, (5985), October 1984, p. 472-474
Ip, Nancy Yuk-Yu; Zigmond, Richard E.
Article

Substance P inhibits the acute stimulation of ganglionic tyrosine hydroxylase activity by a nicotinic agonist

Neuroscience, v. 13, (1), September 1984, p. 217-220
Ip, Nancy Yuk-Yu; Zigmond, R.E.
Article
1983 1

Acute transsynaptic regulation of tyrosine 3-monooxygenase activity in the rat superior cervical ganglion: Evidence for both cholinergic and noncholinergic mechanisms

Proceedings of the National Academy of Sciences of the United States of America, v. 80, (7), 1983, p. 2018-2085
Ip, Nancy Yuk-Yu; Perlman, Robert L.; Zigmond, Richard E.
Article
1982 2

Both nicotinic and muscarinic agonists acutely increase tyrosine 3-monooxygenase activity in the superior cervical ganglion

Journal of Pharmacology and Experimental Therapeutics, v. 223, (2), 1982, p. 280-283
Ip, Nancy Yuk-Yu; Perlman, R.L.; Zigmond, R.E.
Article

Secretin and vasoactive intestinal peptide acutely increase tyrosine 3-monooxygenase in the rat superior cervical ganglion

Proceedings of the National Academy of Sciences of the United States of America, v. 79, (23), December 1982, p. 7566-7569
Ip, Nancy Yuk-Yu; Ho, C.K.; Zigmond, Richard E.
Article
1980 1

Characterization and regulation of receptors for epidermal growth factor in mouse calvaria

Endocrinology, v. 107, (6), December 1980, p. 1738-1746
Shupnik, M.A.; Ip, Nancy Yuk-Yu; Tashjian, A. H. Jr
Article
Article 3

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Communications Medicine, v. 3, April 2023, article number 49
Alzheimer’s Disease Neuroimaging Initiative; Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Lv, Ge; Zhang, Huan; Chen, Jiahang; Ye, Tao; Chen, Yuewen; Zhang, Yulin; Ma, Shuangshuang; Lo, Ronnie M.N.; Tong, Pui Sze; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Guo, Qihao; Mok, Kin Ying Boniface; Shoai, Maryam; Hardy, John; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu

Receptor-ligand interaction controls microglial chemotaxis and amelioration of Alzheimer's disease pathology

Journal of Neurochemistry, v. 166, (6), September 2023, p. 891-903
Lau, Shun Fat; Fu, Kit Yu; Ip, Nancy Yuk-yu

The role of genetic risk factors of Alzheimer's disease in synaptic dysfunction

Seminars in Cell and Developmental Biology, v. 139, April 2023, p. 3-12
Fu, Wing Yu; Ip, Nancy Yuk-Yu
Article 9

AAV Capsid Variants with Brain-Wide Transgene Expression and Decreased Liver Targeting after Intravenous Delivery in Mouse and marmoset

Nature Neuroscience, v. 25, (1), January 2022, p. 106-115
Goertsen, David; Flytzanis, Nicholas C.; Goeden, Nick; Chuapoco, Miguel; Cummins, Alexander; Chen, Yijing; Fan, Yingying; Zhang, Qiangge; Sharma, Jitendra; Duan, Yangyang; Wang, Liping; Feng, Guoping; Chen, Yu; Ip, Nancy Yuk-Yu; Pickel, James; Gradinaru, Viviana

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Nature Aging, v. 2, (7), July 2022, p. 616-634
Jiang, Yuanbing; Zhou, Xiaopu; Wong, Hiu Yi; Ouyang, Li; Ip, Fanny Chui Fun; Chau, Man Ni; Lau, Shun Fat; Wu, Wei; Wong, Yew Kit Daniel; Seo, Heukjin; Fu, Wing Yu; Lai, Chit Hang; Chen, Yuewen; Chen, Yu; Tong, Pui Sze; Alzheimer’s Disease Neuroimaging Initiative; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Mok, Kin Ying Boniface; Shoai, Maryam; Lehallier, Benoit; Losada, Patricia Moran; O'Brien, Eleanor; Porter, Tenielle; Laws, Simon M.; Hardy, John; Wyss-Coray, Tony; Masters, Colin L.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Association of SPI1 haplotypes with altered SPI1 gene expression and Alzheimer’s disease risk

Journal of Alzheimer's Disease, v. 86, (4), April 2022, p. 1861-1873
Cao, Han; Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Chen, Yuewen; Lai, Chit Hang; Lo, Ming Nok; Tong, Pui Sze; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Alzheimer’s Disease Neuroimaging Initiative; Fu, Kit Yu; Ip, Nancy Yuk-yu

Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Nature Biomedical Engineering, v. 6, (2), February 2022, p. 168-180
Duan, Yangyang; Ye, Tao; Qu, Zhe; Chen, Yuewen; Miranda, Abigail Orquiza; Zhou, Xiaopu; Lok, Ka Chun; Chen, Yu; Fu, Kit Yu; Gradinaru, Viviana; Ip, Nancy Yuk-yu

Deep tissue multi-photon imaging using adaptive optics with direct focus sensing and shaping

Nature Biotechnology, v. 40, (11), November 2022, p. 1663-1671
Qin, Zhongya; She, Zhentao; Chen, Congping; Wu, Wanjie; Lau, Ka Yan Jackie; Ip, Nancy Yuk-yu; Qu, Jianan

Demographics and Medication Use of Patients with Late-Onset Alzheimer’s Disease in Hong Kong

Journal of Alzheimer's Disease, v. 87, (3), May 2022, p. 1205-1213
Wong, Hiu Yi; Zhong, Huan; Zhou, Xiaopu; Chan, Phillip Y.C.; Kwok, Timothy C.Y.; Mok, Kin; Hardy, John; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu

Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms

The FEBS Journal, v. 289, (8), April 2022, p. 2202-2218
Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu

Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging

Alzheimer's & Dementia, v. 18, (1), January 2022, p. 88-102
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Nicole C. H.; Cheung, Kit; Lo, Ronnie M. N.; Tong, Pui Sze; Wong, Bonnie W. Y.; Chan, Andrew L. T.; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu

Multi-Omics-Based Autophagy-Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology

Advanced Science, 13 June 2022, article number 2201212
Park, Jong-Chan; Barahona-Torres, Natalia; Jang, So-Young; Mok, KinY.; Kim, HaengJun; Han, Sun-Ho; Cho, Kwang-Hyun; Zhou, Xiaopu; Fu, Amy K.Y.; Ip, Nancy Yuk-yu; Seo, Jieun; Choi, Murim; Jeong, Hyobin; Hwang, Daehee; Lee, Dong Young; Byun, Min Soo; Yi, Dahyun; Han, Jong Won; Mook-Jung, Inhee; Hardy, John
Conference paper 3

An IL1RL1 genetic variant lowers soluble ST2 levels and attenuates the impact of APOE-ε4 in Alzheimer's disease


Jiang, Yuanbing; Zhou, Xiaopu; Wong, Hiu Yi; Ouyang, Li; Ip, Fanny Chui Fun; Chau, Man Ni; Lau, Shun Fat; Wu, Wei; Seo, Heukjin; Fu, Wing Yu; Lai, Chit Hang; Chen, Yuewen; Chen, Yu; Tong, Pui Sze; Alzheimer's Disease Neuroimaging Initiative; Mok, Vincent C.T.; Kwok, Timothy C. Y.; Lehallier, Benoit; Losada, Patricia Morán; O'Brien, Eleanor; Porter, Tenielle; Laws, Simon M.; Wyss-Coray, Tony; Masters, Colin L.; Fu, Kit Yu; Ip, Nancy Yuk-yu

How Long is Enough? Exploring the Optimal Intervals of Long-Range Clinical Note Language Modeling

Proceedings of the 13th International Workshop on Health Text Mining and Information Analysis (LOUHI) / Association for Computational Linguistics. Stroudsburg, USA : Association for Computational Linguistics, 2022, p. 160-172
Cahyawijaya, Samuel; Wilie, Bryan; Lovenia, Holy; Zhong, Mingqian; Zhong, Huan; Ip, Nancy Yuk-yu; Fung, Pascale

SNP2Vec: Scalable Self-Supervised Pre-Training for Genome-Wide Association Study

Proceedings of the 21st Workshop on Biomedical Language Processing / edited by Dina Demner-Fushman, Kevin Bretonnel Cohen, Sophia Ananiadou, Junichi Tsujii. Stroudsburg, USA : Association for Computational Linguistics, 2022, p. 140-154
Cahyawijaya, Samuel; Yu, Tiezheng; Liu, Zihan; Mak, Tiffany T.W.; Zhou, Xiaopu; Ip, Nancy Yuk-yu; Fung, Pascale
Article 16

A near-infrared AIE fluorescent probe for myelin imaging: From sciatic nerve to the optically cleared brain tissue in 3D

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (45), 9 November 2021, article number e2106143118
Wu, Ming-Yu; Wong, Alex Y. H.; Leung, Jong-Kai; Kam, Chuen; Wu, Kenneth Lap-Kei; Chan, Ying-Shing; Liu, Kai; Ip, Nancy Yuk-yu; Chen, Sijie

A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice

European Journal of Medicinal Chemistry, v. 226, December 2021, article number 113827
Ip, Fanny Chui Fun; Fu, Guangmiao; Yang, Fengzhi; Kang, Fangyuan; Sun, Peiran; Ling, Choi Ying; Cheung, Kit; Xie, Fangzhou; Hu, Yueqing; Fu, Lei; Ip, Nancy Yuk-yu

APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention

Current Opinion in Neurobiology, v. 69, August 2021, p. 58-67
Zhou, Xiaopu; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu

Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (1), January 2021, article number e2020810118
Wang, Ye; Fu, Wing Yu; Cheung, Kit; Hung, Kwok Wang; Chen, Congping; Geng, Hongyan; Yung, Wing Ho; Qu, Jianan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Blood transcriptome analysis for Alzheimer' disease in Hong Kong Chinese population

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, v. 17, (S3), December 2021, article number e056643
Zhong, Huan; Zhou, Xiaopu; Jiang, Yuanbing; Chen, Yu; Lai, N.C.H.; Tong, Pui Sze; Lo, Ronnie M.N.; Kwok, Timonthy C.Y.; Mok, Vincent C.T.; Ip, Fanny Chui Fun; Mok, Kin Ying Boniface; Hardy, John; Fu, Kit Yu; Ip, Nancy Yuk-yu

Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Cellular and Molecular Life Sciences, 13 April 2021
Lau, Shun Fat; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Deep learning for polygenic score analysis for Alzheimer's disease risk prediction in the Chinese population

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, v. 17, (S3), December 2021, article number e056625
Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Yuewen; Chen, Jiahang; Zhang, Yulin; Ma, Shuangshuang; Lai, Nicole Chit Hang; Lo, Ronnie M.N.; Cheung, Kit; Tong, Pui Sze; Mok, Kin Ying Boniface; Hardy, John; Guo, Qihao; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Communications Biology, v. 4, (1), February 2021, article number 195
Ye, Tao; Duan, Yangyang; Tsang, Hayley Wing Sum; Xu, He; Chen, Yuewen; Cao, Han; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

GSAP Regulates Lipid Homeostasis and Mitochondrial Function Associated with Alzheimer's Disease

Journal of Experimental Medicine, v. 218, (8), June 2021, article number e20202446
Xu, Peng; Chang, Jerry C.; Zhou, Xiaopu; Wang, Wei; Bamkole, Michael; Wong, Eitan; Bettayeb, Karima; Jiang, Lu-Lin; Huang, Timothy; Luo, Wenjie; Xu, Huaxi; Nairn, Angus C.; Flajolet, Marc; Ip, Nancy Yuk-yu; Li, Yue-Ming; Greengard, Paul

High-resolution two-photon transcranial imaging of brain using direct wavefront sensing

Photonics Research, v. 9, (6), June 2021, p. 1144-1156
Chen, Congping; Qin, Zhongya; He, Sicong; Liu, Shaojun; Lau, Shun Fat; Wu, Wanjie; Zhu, Dan; Ip, Nancy Yuk-yu; Qu, Jianan

IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry

DNA and Cell Biology, v. 40, (9), September 2021, p. 1125-1130
Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

Scientific Reports, v. 11, (1), February 2021, article number 4359
Lau, Ka Yan Jackie; Tian, Min; Shen, Yang; Lau, Shun Fat; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Polygenic Score Models For Alzheimer’s Disease: From Research To Clinical Applications

Frontiers in Neuroscience, v. 15, 29 March 2021, article number 650220
Zhou, Xiaopu; Li, Yolanda Yuen Tung; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu

Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model

STAR Protocols, v. 2, (1), March 2021, article number 100265
Lau, Shun Fat; Wu, Wei; Seo, Heukjin; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Retinal Dysfunction In Alzheimer’s Disease And Implications For Biomarkers

Biomolecules, v. 11, (8), August 2021, article number 1215
Liao, Chunyan; Xu, Jinying; Chen, Yu; Ip, Yuk-yu, Nancy

Rhynchophylline Administration Ameliorates Amyloid-beta Pathology and Inflammation in an Alzheimer's Disease Transgenic Mouse Model

ACS Chemical Neuroscience, v. 12, (22), November 2021, p. 4249-4256
Fu, Wing Yu; Hung, Kwok Wang; Lau, Shun Fat; Butt, Busma; Yuen, Wai Hin; Fu, Guangmiao; Chan, Chi Wai; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper 3

A high-performance biomarker panel for Alzheimer's disease screening and staging identified by large-scale plasma proteomic profiling


Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Chit Hang; Cheung, Kit; Lo, Ming Nok; Tong, Pui Sze; Wong, Wing Yan; Chan, Andrew L.T.; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-Yu

A high-performance biomarker panel for Alzheimer's disease screening and staging identified by large-scale plasma proteomic profiling

The Journal of the Alzheimer’s Association, v. 17, (S5), December 2021, article number e056099, Supplement: Biomarkers – Part 2
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Chit Hang; Cheung, Kit; Lo, Ming Nok; Tong, Pui Sze; Wong, Wing Yan; Chan, Andrew L.T.; Mok, Vincent C.T.; Kwok, Timonthy C.Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu

Deep learning for polygenic score analysis for Alzheimer’s disease risk prediction in the Chinese population


Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Yuewen; Chen, Jiahang; Zhang, Yulin; Ma, Shuangshuang; Lai, Chit Hang; Lo, Ming Nok; Cheung, Kit; Tong, Pui Sze; Mok, Kin Ying Boniface; Hardy, John; Guo, Qihao; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article 6

A Pentacyclic Triterpene from Ligustrum lucidum Targets γ-Secretase

ACS Chemical Neuroscience, v.11, (18), 16 September 2020, p. 2827-2835
Luo, Wenjie; Ip, Fanny Chui Fun; Fu, Guangmiao; Cheung, Kit; Tian, Yuan; Hu, Yueqing; Sinha, Anjana; Cheng, Elaine Y.L.; Wu, Xianzhong; Bustos, Victor; Greengard, Paul; Li, Yue-Ming; Sinha, Subhash C.; Ip, Nancy Yuk-yu

Adaptive optics two-photon endomicroscopy enables deep-brain imaging at synaptic resolution over large volumes

Science Advances, v. 6, (40), 30 September 2020, article number eabc6521
Qin, Zhongya; Chen, Congping; He, Sicong; Wang, Ye; Tam, Kam Fai; Ip, Nancy Yuk-Yu; Qu, Jianan

Genetic and polygenic risk score analysis for Alzheimer’s disease in the Chinese population

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, v. 12, (1), August 2020, article number e12074
Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Lai, Nicole C.H.; Li, Yuen Tung; Jiang, Yuanbing; Zhong, Huan; Chen, Yuewen; Zhang, Yulin; Ma, Shuangshuang; Lo, Ronie M.N.; Cheung, Kit; Tong, Pui Sze; Ko, Ho; Shoai, Maryam; Mok, Kin Ying Boniface; Hardy, John; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Fu, Kit Yu; Ip, Nancy Yuk-yu

IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease

Cell Reports, v. 31, (3), April 2020, article number 107530
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu

p39-associated Cdk5 activity regulates dendritic morphogenesis

Scientific Reports, v. 10, (1), December 2020, article number 18746
Ouyang, Li; Chen, Yu; Wang, Ye; Chen, Yuewen; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-yu

Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America, v. 117, (41), 13 October 2020, p. 25800-25809
Lau, Shun Fat; Cao, Han; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper 1

Adaptive optics two-photon microendoscopy for high-resolution and deep-brain imaging in vivo

Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 11226, February 2020, article number 1122606
Chen, Congping; Qin, Zhongya; He, Sicong; Wu, Wanjie; Wang, Ye; Tam, Kam Fai; Ip, Nancy Yuk-Yu; Qu, Jianan
Article 7

Asymmetric Total Syntheses of Rhynchophylline and Isorhynchophylline

Journal of Organic Chemistry, v. 84, (17), August, 2019, p. 11359-11365
Zhang, Zhihong; Zhang, Wei; Kang, Fangyuan; Ip, Chui Fun Fanny; Ip, Nancy Yuk-yu; Tong, Rongbiao

Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer's Disease

ACS Chemical Neuroscience, v. 10, (9), August 2019, p. 3986-3996
Chen, Yuewen; Xu, Jinying; Zhou, Xiaopu; Liu, Saijuan; Zhang, Yulin; Ma, Shuangshuang; Fu, Kit Yu; Ip, Nancy Yuk-yu; Chen, Yu

Increased Axin expression enhances adult hippocampal neurogenesis and exerts an antidepressant effect

Scientific Reports, v. 9, February 2019, article number 1190, p. 1-10
Chen, Weiwei; Fu, Wing Yu; Su, Yiting; Fang, Weiqun; Fu, Amy K. Y.; Ip, Nancy Yuk-yu

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Nature Communications, v. 10, (1), December 2019, article number 3310
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Kwok, Timothy C. Y.; Mok, Vincent C. T.; Guo, Qihao; Ip, Chui Fun Fanny; Chen, Yuewen; Mullapudi, Nandita; Giusti-Rodríguez, Paola; Sullivan, Patrick F.; Hardy,John; Fu, Kit Yu; Li, Yun; Ip, Nancy Yuk-yu

Synaptic Dysfunction in Alzheimer's Disease: Mechanisms and Therapeutic Strategies

Pharmacology and Therapeutics, v. 195, March 2019, p. 186-198
Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu

Targeting Neuroinflammation as a Therapeutic Strategy for Alzheimer's Disease: Mechanisms, Drug Candidates, and New Opportunities

ACS Chemical Neuroscience, v. 10, (2), February 2019, p. 872-879
Fu, Wing-Yu; Wang, Xiujiao; Ip, Nancy Yuk-yu

α2-chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis

Proceedings of the National Academy of Sciences of the United States of America, v. 116, (27), June 2019, p. 13651-13660
Su, Yiting; Lau, Shun Fat; Ip, P.K. Jacque; Cheung, Kit; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper 7

Adaptive Optics Two-photon Microscopy for in Vivo Imaging of Cortex and Hippocampus in Mouse Brain

Proceedings of SPIE - Neural Imaging and Sensing, v. 10865, 2019, article number 108650M
Chen, Congping; Qin, Zhongya; He, Sicong; Lui, Yan Lik Caleb; Ip, Nancy Yuk-Yu; Qu, Jianan

Deregulation of IL-33/ST2 signaling in Alzheimer’s disease


Jiang, Yuanbing; Zhou, Xiaopu; Wang, Ye; Lai, N.C.H.; Tong, Pui Sze; Mok, V.C.T.; Kwok, T.C.Y.; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu

IL-33/ST2 signaling promotes excitatory synapse formation in the hippocampus


Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

IL-33-dependent transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease


Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk


Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Kwok, T.C.Y.; Mok, V.C.T.; Guo, Q.; Ip, Fanny C.F.; Chen, Y.; Mullapudi, Nandita; Hardy, J.; Fu, Kit Yu; Li, Y.; Ip, Nancy Yuk-yu

Role of IL-33/ST2 signaling in homeostatic synaptic plasticity in the hippocampus


Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Whole-genome sequencing for Alzheimer’s disease risk in the Chinese population


Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Mok, V.C.T.; Guo, Q.; Ip, Fanny C.F.; Chen, Y.; Hardy, J.; Li, Y.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article 7

Avian influenza A H7N9 virus infects human astrocytes and neuronal cells and induces inflammatory immune responses.

Journal of NeuroVirology, v. 24, (6), December 2018, p. 752-760
Ng, Yu Pong; Yip, TF; Malik peiris, JS; Ip, Nancy Yuk-yu; Lee, SMY

Dopamine receptors mediate strategy abandoning via modulation of a specific prelimbic cortex-nucleus accumbens pathway in mice

Proceedings of the National Academy of Sciences of the United States of America, v. 115, (21), May 2018, p. E4890-E4899
Cui, Qiaoling; Li, Qian; Geng, Hongyan; Chen, Lei; Ip, Nancy Yuk-yu; Ke, Ya; Yung, Wing-Ho

Identification of Genetic Risk Factors in The Chinese Population Implicates a Role of the Immune System in Alzheimer’s Disease Pathogenesis

Proceedings of the National Academy of Sciences of the United States of America, v. 115, (8), February 2018, p. 1697-1706
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Zhao, Qianhua; Chen, Keliang; Chen, Yuewen; Hardy, John; Li, Yun; Fu, Kit Yu; Guo, Qihao; Ip, Nancy Yuk-yu

Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs

Scientific Reports, v. 8, (1), May 2018, article number 7377, p. 1-7
Gu, shuo; Fu, Wing Yu; Fu, Kit Yu; Tong, Pui See; Ip, Fanny Chui-Fun; Huang, Xuhui; Ip, Nancy Yuk-Yu

In Vivo Near-Infrared Two-Photon Imaging of Amyloid Plaques in Deep Brain of Alzheimer’s Disease Mouse Model

ACS Chemical Neuroscience, v. 9, (12), December 2018, p. 3128-3136
Chen, Congping; Liang, Zhuoyi; Zhou, Biao; Li, Xuesong; Lui, Yan Lik Caleb; Ip, Nancy Yuk-yu; Qu, Jianan

Methods to study the signal transduction of the surface receptor tyrosine kinase TrkB in neurons

Methods in Molecular Biology, v. 1722, 2018, p. 211-222
Lai, Kwok On; Ip, Nancy Yuk-yu

Two Pairs of Unusual Melibiose and Raffinose Esters From Scrophularia Ningpoensis

Journal of Asian Natural Products Research, v. 20, (3), March 2018, p. 255-262
Zhang, Jun; Liang, Yang; Ip, Fanny C. F.; Ip, Nancy Yuk-yu; Liu, Ting-Ting; Zhong, Ba-Lian; Xu, Shi-Hai
Conference paper 2

Deep brain two-photon NIR fluorescence imaging for study of Alzheimer’s disease

Proceedings of SPIE: Neural Imaging and Sensing 2018, v. 10481, May 2018, article number 104810A, Progress in Biomedical Optics and Imaging
Chen, Congping; Liang, Zhuoyi; Zhou, Biao; Ip, Nancy Yuk-Yu; Qu, Jianan

IL-33/ST2 signaling enhances the formation of excitatory synapses in the hippocampus


Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article 6

A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes

Developmental Cell, v. 41, (4), May 2017, p. 382-391.e5
An, Yitai; Wang, Gang; Diao, Yarui; Long, Yanyang; Fu, Xinrong; Weng, Mingxi; Zhou, Liang; Sun, Kun; Cheung, Tom H.; Ip, Nancy Yuk-yu; Sun, Hao; Wang, Huating; Wu, Zhenguo

A New Iridoid Glycoside and a New Cinnamoyl Glycoside from Scrophularia Ningpoensis Hemsl

Natural Product Research, v. 31, (20), March 2017, p. 2361-2368
Zhang, Jun; Ip, Fanny C. F.; Liang, Yan; Ip, Nancy Yuk-yu; Zhong, Ba-Lian; Lai, Chun-Wang; Xu, Shi-Hai

Anemoside A3 Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating T Helper 17 Cell Response

PLoS ONE, v. 12, (7), July 2017, article number e0182069
Ip, Fanny; Ng, Yupong; Or, Terry Cho Tsun; Sun, Peiran; Fu, Guangmiao; Li, Jessica Y.H.; Ye, Wencai; Cheung, Tom H.; Ip, Nancy Y.Y.

Cdk5-Dependent Phosphorylation of Liprinα1 Mediates Neuronal Activity-Dependent Synapse Development

Proceedings of the National Academy of Sciences of the United States of America, v. 114, (33), August 2017, p. E6992-E7001
Huang, Huiqian; Lin, Xiaochen; Liang, Zhuoyi; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu

Homeostatic Scaling of AMPA Receptors by Semaphorin

Neuron, v. 96, (5), 6 December 2017, p. 955-958
Fu, Kit Yu; Ip, Nancy Yuk-Yu

Regulation of postsynaptic signaling in structural synaptic plasticity

Current Opinion in Neurobiology, v. 45, Aug 2017, p. 148-155
Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper 2

Activation of the melanocortin 4 receptor signaling pathway ameliorates Alzheimer’s disease-like pathology


Tian, Min; Shen, Yang; Fu, Kit Yu; Ip, Nancy Yuk-Yu

IL-33 enhances the development of hippocampal excitatory synapses


Hung, Kwok Wang; Wang, Ye; Chuang, Ching Yi; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Article 11

China Brain Project: Basic Neuroscience, Brain Diseases, and Brain-Inspired Computing

Neuron, v. 92, (3), November 2016, p. 591-596
Poo, Mu-ming; Du, Jiu-lin; Ip, Nancy Y. Y.; Xiong, Zhi-Qi; Xu, Bo; Tan, Tieniu

Design and Synthesis of Dimeric Securinine Analogs with Neuritogenic Activities

ACS Chemical Neuroscience, v. 7, (10), October 2016, p. 1442-1451
Tang, Genyun; Liu, Xin; Ma, Nan; Huang, Xiaojie; Wu, Zhen-Long; Zhang, Wen; Wang, Ying; Zhao, Bing-Xin; Wang, Zhen-Ya; Ip, Fanny C. F.; Ip, Nancy Y. Y.; Ye, Wen-Cai; Shi, Lei; Chen, Wei-Min

Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition)

Autophagy, v. 12, (1), January 2016, p. 1-222
Ip, Nancy Yuk-Yu

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline

Proceedings of the National Academy of Sciences of the United States of America, v. 113, (19), May 2016, p. 2705-2713
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu

Multicolor 4D fluorescence microscopy using ultrathin bessel light sheets

Scientific Reports, v. 6, May 2016, article number 26159
Zhao, Teng; Lau, Sze Cheung; Wang, Ying; Su, Yumian; Wang, Hao; Cheng, Aifang; Herrup, Karl; Ip, Nancy Y.; Du, Shengwang; Loy, M.M.T.

Neuroprotective Effect of a Novel Chinese Herbal Decoction on Cultured Neurons and Cerebral Ischemic Rats

BMC Complementary and Alternative Medicine, v. 16, (1), November 2016, article number 437
Ip, Fanny Chui-Fun; Zhao, Yuming; Chan, Kim Wan; Cheng, Elaine Yee Ling; Tong, Estella Pui Sze; Chandrashekar, Oormila; Fu, Guangmiao; Zhao, Zhong-Zhen; Ip, Nancy Yuk-Yu

New Lignans with Neuroprotective Activity from Adelostemma Gracillimum

Phytochemistry Letters, v. 16, June 2016, p. 1-7
Zhang, Jun; Guo, Shengjun; Chan, Kim Wan; Tong, Pui Sze; Fu, Guangmiao; Mu, Quanzhang; Ip, Fanny C.F.; Ip, Nancy Y.Y.

STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration

Cell Reports, v. 16, (8), 23 August 2016, p. 2102-2115
Zhu, Han; Xiao, Fang; Wang, Gang; Wei, Xiuqing; Jiang, Lei; Chen, Yan; Zhu, Lin; Wang, Haixia; Diao, Yarui; Wang, Huating; Ip, Nancy Y Y; Cheung, Tom H.; Wu, Zhenguo

Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer’s Disease Model

Cell Reports, v. 17, (7), November 2016, p. 1819-1831
Shen, Yang; Tian, Min; Zheng, Yuqiong; Gong, Fei; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu

The Pseudokinase CaMKv is Required for the Activity-dependent Maintenance of Dendritic Spines

Nature Communications, v. 7, October 2016, article number 13282
Liang, Zhuoyi; Zhan, Yi; Shen, Yang; Wong, Catherine C.L.; Yates, John R.R.; Plattner, Florian; Lai, Kwok On; Ip, Nancy Y.Y.

Worldwide initiatives to advance brain research

Nature Neuroscience, v. 19, (9), August 2016, p. 1118-1122
Grillner, Sten; Ip, Nancy Y Y; Koch, Christof; Koroshetz, Walter; Okano, Hideyuki; Polachek, Miri; Poo, Mu-ming; Sejnowski, Terrence Joseph
Conference paper 18

Cdk5 Activity is Required for EphB-mediated Synaptogenesis


Chen, Yu; Wong, Yung Hou; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Cdk5-mediated Phosphorylation of Liprinα1 is Critical for Synaptic Plasticity


Huang, Huiqian; Lin, Xiaochen; Liang, Zhuoyi; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu

Characterization of Pathogenic Mutations and Cellular Phenotypes of Alzheimer’s Disease using Human Induced Pluripotent Stem Cells


Ip, Nancy Yuk-Yu; Fu, Kit Yu; Tong, Pui Sze; Tu, X.; Ye, Tao

Coronin 2B is an Important Regulator of Neuronal Polarization


Chen, Yu; Chen, Y.; Zhang, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Elucidation of the Functional Roles of Rho GTPase-activating Proteins in Adult Neurogenesis


Su, Yiting; Ip, Pak Kan; Min, Lan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Elucidation of the Functional Roles of Rho GTPase-Activating Proteins in Adult Neurogenesis


Su, Yiting; Ip, Nancy Yuk-Yu; Min, L.; Ip, Pak Kan; Fu, Kit Yu

Fine Mapping of the APOE Locus by Low-pass Whole-genome Sequencing in Chinese Alzheimer’s Disease Patients


Zhou, Xiaopu; Chen, Yu; Zhao, Q.; Chu, M.K.M.; Kwok, C.T.; Mok, K.Y.; Zhang, B.; Fu, Kit Yu; Li, Y.; Guo, Q.; Ip, Nancy Yuk-yu

Functional roles of Rho GTPase-activating proteins in adult neurogenesis


Su, Yiting; Ip, Nancy Yuk-Yu; Ip, Pak Kan; Min, L.; Fu, Kit Yu

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline


Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, I.C.W.; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu

IL-33 ameliorates cognitive deficits and amyloid pathology in an Alzheimer’s disease-like mouse model


Fu, Kit Yu; Hung, Kwok Wang; Yuen, M.Y.F.; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Cheung, Tom; Zhang, B; Fu, Wing Yu; Liew, F.Y.; Ip, Nancy Yuk-yu

IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model


Zhou, Xiaopu; Ip, Nancy Yuk-yu; Cheung, Tom; Liew, F.Y.; Chan, I.C.W.; Mak, D.S.Y.; Yuen, M.Y.F.; Hung, Kwok Wang; Fu, Kit Yu; Fu, Wing Yu

IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model


Ip, Nancy Yuk-Yu

IL-33 Modulates the Inflammatory Response in the Brains of Alzheimer’s disease mouse model


Fu, Wing Yu; Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Liew, F.Y.; Cheung, Tom H.; Ip, Nancy Yuk-yu

MC4R Activation Alleviates Amyloid-Beta–Induced Synaptic Dysfunction


Gong, Fei; Shen, Yang; Tian, Min; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Melanocortin 4 Receptor Activation Ameliorates Synaptic Plasticity Impairment in a Mouse Model of Alzheimer’s Disease


Ip, Nancy Yuk-Yu; Lai, Kwok On; Plattner, F.; Yates, III; John, R.; Wong, C.C.L.; Shen, Yang; Zhan, Y.; Liang, Zhuoyi

The Pseudokinase CaMKv Is Required for the Activity-Dependent Maintenance of Dendritic Spines


Liang, Zhuoyi; Zhan, Yi; Shen, Yang; Wong, Catherine C.L.; Yates, John R.R.; Plattner, Florian; Lai, Kwok On; Ip, Nancy Yuk-Yu; John, R.

The Pseudokinase CaMKv Is Required For The Activity-Dependent Maintenance of Dendritic Spines


Liang, Zhuoyi; Zhan, Yi; Shen, Yang; Wong, Catherine C.L.; Yates, John R.R.; Plattner, Florian; Lai, Kwok On; Ip, Nancy Yuk-Yu

Understanding the Melanocortin Microcircuit in the Mouse Hippocampus


Tian, Min; Ip, Nancy Yuk-Yu; Fu, Kit Yu; Zheng, Y.Q.; Shen, Yang
Article 16

Anemoside A3 enhances cognition through the regulation of synaptic function and neuroprotection

Neuropsychopharmacology, v. 40, (8), July 2015, p. 1877-1887
Ip, Fanny Chun Fun; Fu, Wingyu; Cheng, Elaineyl; Tong, Estellaps; Lok, Kachun; Liang, Yan; Ye, Wencai; Ip, Nancy Yuk Yu

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling

PLoS ONE, v. 10, (7), July 2015, article number e0133115
Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Chen, Yuewen; Zhou, Xiaopu; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu

Cdk5 regulates activity-dependent gene expression and dendrite development

Journal of Neuroscience, v. 35, (45), November 2015, p. 15127-15134
Liang, Zhuoyi; Ye, Tao; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk Yu

Cdk5: A Key Player at Neuronal Synapse with Diverse Functions

Mini-Reviews in Medicinal Chemistry, v. 15, (5), 2015, p. 390-395
Lai, Kwok-On; Ip, Nancy Y.Y.

Challenges and opportunities in bioscience for women in China

Asian Biotechnology and Development Review, v. 17, (1), 2015, p. 7-14
Ip, Nancy Yuk-yu

ChemInform Abstract: Highly trans-Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ-Deoxygenation and Heck—Matsuda Reaction: Asymmetric Total Synthesis of (-)-Musellarins A—C (I) and Their Analogues

ChemInform, v. 46, (49), December 2015
Li, Zhilong; Ip, Fanny C.F.; Ip, Nancy Y.Y.; Tong, Rongbiao

Cyclin-dependent kinase 5 (Cdk5)-dependent phosphorylation of p70 ribosomal S6 kinase 1 (S6K) is required for dendritic spine morphogenesis

Journal of Biological Chemistry, v. 290, (23), June 2015, p. 14637-14646
Lai, Kwok-On; Liang, Zhuoyi; Fei, Erkang; Huang, Huiqian; Ip, Nancy Yuk Yu

Emerging roles of axin in cerebral cortical development

Frontiers in Cellular Neuroscience, v. 9, June 2015, article number 217, p. 1-8
Ye, Tao; Fu, Kit Yu; Ip, Nancy Y.Y.

Highly trans-Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ-Deoxygenation and Heck-Matsuda Reaction: Asymmetric Total Synthesis of (-)-Musellarins A-C and Their Analogues

Chemistry - A European Journal, v. 21, (31), 2015, p. 11152-11157
Li, Zhilong; Ip, Fanny Chui Fun; Ip, Nancy Yuk-Yu; Tong, Rongbiao

Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons

Neurobiology of Disease, v. 73, January 2015, p. 366-376
Li, Songshan; He, Qinghai; Wang, Hao; Tang, Xuming; Ho, Kam Wing; Gao, Xin; Zhang, Qian; Shen, Yang; Cheung, Annie; Wong, Francis; Wong, Yung Hou; Ip, Nancy Yuk-yu; Jiang, Liwen; Yung, Wing Ho; Liu, Kai

Neddylation is needed for synapse maturation

Nature Neuroscience, v. 18, (2), February 2015, p. 164-166
Fu, Kit Yu; Ip, Nancy Y.Y.

Neurodegenerative Diseases: What Is to Be Done?

Translational Neuroscience: Toward New Therapies, v. 7, 2015, p. 93-113
Holtzman, D.M.; Nikolich, K.; Pangalos, M.N.; Broich, K.; Ip, Nancy Y.Y.; Koo, E.H.; Koroshetz, W.J.; Masliah, E.; Mucke, L.; Nicotera, P.; Schnaars, M.; Spillantini, M.G.

Ningpoensines A-C: Unusual zwitterionic alkaloids from Scrophularia ningpoensis

Tetrahedron Letters, v. 56, (40), September 2015, p. 5453-5456
Zhang, Jun; Ip, Fanny; Tong, Estellaps; Chan, Kimwan; Li, Liangchun; Ng, Yupong; Ip, Nancy Y.

NRC-interacting factor directs neurite outgrowth in an activity-dependent manner

Neuroscience, v. 289, March 2015, p. 207-213
Zhao, Xiao Su; Fu, Wing Yu; Hung, Kwok Wang; Chien, Winnie W.Y.; Li, Zhongrui; Fu, Kit Yu; Ip, Nancy Y.Y.

Plant alkaloids as drug leads for Alzheimer's disease

Neurochemistry International, v. 89, October 2015, p. 260-270
Ng, Yu Pong; Or, Terry Cho Tsun; Ip, Nancy Yuk-Yu

S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength

Nature Communications, v. 6, October 2015, article number 8665
Zhang, Peng; Fu, Wingyu; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Conference paper 14

Activity-Dependent Regulation of Liprinα1 Phosphorylation During Synapse Development


Huang, Huiqian; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Activity-Dependent Regulation of Liprinα1 Phosphorylation During Synapse Development


Huang, Huiqian; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Axin Regulates Dendritic Spine Development via Cdc42 Signaling


Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Zhou, Xiaopu; Fang, Weiqun; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development


Liang, Zhuoyi; Ye, Tao; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu

Cdk5-Dependent Phosphorylation of p70 Ribosomal s6 Kinase (S6K) Is Required for Dendritic Spine Morphogenesis


Liang, Zhuoyi; Lai, Kwok On; Fei, Erkang; Huang, Huiqian; Ip, Nancy Yuk-Yu

From Understanding Synaptic Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu

Integrating Basic and Translational Research for Brain Disorders


Ip, Nancy Yuk-Yu

MC4R Signaling Modulation Ameliorates Synaptic Dysfunction in Alzheimer’s Disease Models


Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Melanocortin 4 Receptor Signaling Modulation Ameliorates Synaptic Dysfunction in Alzheimer's Disease Models


Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Modulation of Melanocortin 4 Receptor Signaling Ameliorates Synaptic Dysfunction in Alzheimer's Disease Models


Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Wing Yu; Ip, Nancy Yuk-Yu

Role of Cdk5 in Activity-Induced Gene Expression and Dendrite Development


Ye, Tao; Liang, Zhuoyi; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu

S-Nitrosylation–Dependent Proteasomal Degradation Restricts cdk5 Activity to Regulate Hippocampal Synaptic Strength


Fu, Kit Yu; Zhang, Peng; Fu, Wing Yu; Ip, Nancy Yuk-Yu

Synaptic Plasticity in Health and Disease


Ip, Nancy Yuk-Yu

The EphA4 Inhibitor Rhynchophylline Ameliorates Disease Pathology in a Mouse Model of Alzheimer's Disease


Fu, Wing Yu; Butt, Busma Wai Yin; Hung, Kwok Wang; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article 10

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America, v. 111, (27), July 2014, p. 9959-9964
Fu, Amy Kit Yu; Hung, Kwok Wang; Huang, Huiqian; Gu, Shuo; Shen, Yang; Cheng, Elaine Yee Ling; Ip, Fanny C.F.; Huang, Xuhui; Fu, Wing Yu; Ip, Nancy Yuk Yu

Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition

Journal of Neuroscience, v. 34, (22), May 2014, p. 7425-7436
Tang, Jing; Ip, Pak Kan; Ye, Tao; Ng, Yu Pong; Yung, Wing-Ho; Wu, Zhenguo; Fang, Weiqun; Fu, Kit Yu; Ip, Nancy Yuk Yu

Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex

Nature Communications, v. 5, September 2014, article number 4826
Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton

Journal of Neuroscience, v. 34, (7), 2014, p. 2413-2421
Chen, Yuewen; Ip, Fanny Chui Fun; Shi, Lei; Zhang, Zhe; Tang, Huibin; Ng, Yu Pong; Ye, Wen-Cai; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu

CRMP2: Functional roles in neural development and therapeutic potential in neurological diseases

Neuroscientist, v. 20, (6), December 2014, p. 589-598
Ip, Jacque P.K.; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu

Cycloastragenol Is a Potent Telomerase Activator in Neuronal Cells: Implications for Depression Management

NeuroSignals, v. 22, (1), May 2014, p. 52-63
Ip, Fanny Chui Fun; Ng, Yu Pong; An, Hui Jin; Dai, Ying; Pang, Hai Hong; Hu, Yue Qing; Chin, Allison C.; Harley, Calvin B.; Wong, Yung Hou; Ip, Nancy Yuk-Yu

Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice

Cell Reports, v. 9, (5), December 2014, p. 1635-1644
Fang, Wei-Qun; Chen, Wei-Wei; Jiang, Liwen; Liu, Kai; Yung, Wing-Ho; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

p35 Regulates the CRM1-Dependent Nucleocytoplasmic Shuttling of Nuclear Hormone Receptor Coregulator-Interacting Factor 1 (NIF-1)

PLoS ONE, v. 9, (10), October 2014, article number e110584
Zhao, Xiao-Su; Fu, Wing-Yu; Chien, Winnie W.Y.; Li, Zhen; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

老年痴呆症的分子机制

生命科学=Chinese Bulletin of Life Sciences, v. 26, (6), June 2014, p. 550-559
沈陽; 陳宇; 傅潔瑜; 葉玉如

老年癡呆癥——現代腦科學和醫學研究面臨的嚴峻挑戰

生命科學=Chinese Bulletin of Life Sciences, v. 26, (1), January 2014, p. 1
葉玉如
Conference paper 28

Activity-Dependent Regulation of Liprinα1 During Synapse Development


Huang, Huiqian; Lai, Kwok On; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Axin Regulates Synapse Development in the Hippocampus


Liang, Z.; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Blockade of EphA4 Signaling Alleviates Alzheimer's Disease-associated Impairment of Hippocampal Synaptic Plasticity


Hung, Kwok Wang; Fu, Kit Yu; Huang, Huiqian; Gu, Shuo; Cheng, Yee Ling; Ip, Fanny Chui Fun; Fu, Wing-Yu; Ip, Nancy Yuk-Yu

Blockade of EphA4 Signaling Alleviates the Impairment of Hippocampal Synaptic Plasticity Associated With Alzheimer's Disease


Fu, Amy Kit Yu; Hung, Nelson Kwok Wang; Huang, Huiqian; Gu, S.; Shen, Yang; Cheng, Yee Ling; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu

Cdk5-mediated Phosphorylation of RapGEF2 Controls Neuronal Migration in the Developing Cortex


Ye, Tao; Ip, Jacque P.K.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Cdk5-Mediated Phosphorylation of RapGEF2 Controls Neuronal Migration in the Developing Cortex


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Cdk5-Mediated Phosphorylation of RapGEF2 Is Required for Neuronal Migration During Cerebral Cortex Development


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Chinese Medicine in Brain Disorders – Traditional Chinese Medicine-Based Drugs for Treating Brain Disorders


Ip, Nancy Yuk-Yu

Cycloastragenol Is a Potent Telomerase Activator in Neuronal Cells: Implications for Depression Management


Ng, Yu Pong; Ip, Fanny Chui Fun; Fu, Wing Yu; Ip, Nancy Yuk-Yu

From Understanding Neural Plasticity to Drug Discovery for Neurodegenerative Diseases


Ip, Nancy Yuk-Yu

From understanding synaptic plasticity to drug discovery for neurodegenerative diseases

Journal of Neurochemistry, v. 130, August 2014
Ip, Nancy Yuk-Yu

Functional Role of Axin in Synapse Development


Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

Functional Role of Axin in Synapse Development


Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Functional Roles of Melanocortin-4 Receptor in Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Ada W.Y.; Cheng, Elaine; Tian, Min; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

Identification and Characterization of Small Molecule EphA4 Inhibitors as Disease Modifiers for Alzheimer's Disease


Fu, Ada Wing Yu; Hung, Nelson Kwok Wang; Gu, Shuo; Xu, Junyu; Su, A.; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Identification of Novel EphA4 Inhibitors as a Disease-Modifying Treatment for Alzheimer's Disease


Fu, Wing-Yu; Hung, Nelson Kwok Wang; Gu, Shuo; Xu, Jzajing; Su, Audrey; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Melanocortin-4 Receptor Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Ada Wing Yu; Cheng, Yee Ling; Tian, Min; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a PKA-dependent mechanism


Shen, Yang; Fu, Ada W.Y.; Cheng, Yee Ling; Tian, Min; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

Receptor Tyrosine Kinase-dependent Signaling in Synaptic Plasticity and Neurodegenerative Diseases


Ip, Nancy Yuk-Yu

Regulation and Functions of Liprinα1 in Activity-dependent Synapse Development


Huang, H.Q.; Lai, Kwok On; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

S-nitrosylation of Cdk5 and its Activator p35 in Neuronal Morphogenesis and Synaptic Function


Zhang, Peng; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

S-Nitrosylation of Cdk5 and Its Activator p35 in Neuronal Morphogenesis and Synaptic Function


Zhang, Peng; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

S-Nitrosylation of Cyclin-Dependent Kinase 5 and Its Activator p35 Is Crucial for Neuronal Morphogenesis and Synaptic Function


Zhang, Peng; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

Targeting Synaptic Dysfunctions in Alzheimer's Disease


Ip, Nancy Yuk-Yu

The Role of Axin in Dendrite and Spine Development


Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

The Role of Axin in Dendrite and Spine Development


Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

The Role of Liprinα1 in Activity-Dependent Regulation of Synapse Development


Huang, Huiqian; Lai, K.O.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

The Role of Nuclear Cdk5 in Activity-induced Gene Expression during Dendrite Development


Liang, Zhuoyi; Chen, Yu; Lai, Kwok On; Ip, Nancy Yuk-Yu
Article 9

Axin Directs the Amplification and Differentiation of Intermediate Progenitors in the Developing Cerebral Cortex

Neuron, v. 79, (4), August 2013, p. 665-679
Fang, Weiqun; Chen, Weiwei; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Axin: An emerging key scaffold at the synapse

IUBMB Life, v. 65, (8), August 2013, p. 685-691
Chen, Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu

Cdk5 Phosphorylates a Component of the HDAC Complex and Regulates Histone Acetylation during Neuronal Cell Death

NeuroSignals, v. 21, (1-2), February 2013, p. 55-60
Fu, Kit Yu; Hung, Kwok Wang; Wong, Hovy Ho-Wai; Fu, Wing Yu; Ip, Nancy Y.Y.

Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors

Bioorganic and Medicinal Chemistry, v. 21, (3), February 2013, p. 676-683
Hu, Yueqing; Zhang, Jun; Chandrashankra, Oormila; Ip, Fanny C.F.; Ip, Nancy Y.

Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-Dependent Mechanism

Journal of Neuroscience, v. 33, (2), January 2013, p. 464-472
Shen, Yang; Fu, Wing-Yu; Cheng, Elaine Y.L.; Fu, Amy K.Y.; Ip, Nancy Y.

Olean-12-Eno[2,3-c] [1,2,5]Oxadiazol-28-Oic Acid (OEOA) Induces G1 Cell Cycle Arrest and Differentiation in Human Leukemia Cell Lines

PLoS ONE, v. 8, (5), May 2013, article number e63580
Ng, Yu Pong; Chen, Yuewen; Hu, Yueqing; Ip, Fanny Chui Fun; Ip, Nancy Yuk Yu

Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders

Biochimica et Biophysica Acta - Molecular Basis of Disease, v. 1832, (12), December 2013, p. 2257-2263
Lai, Kwok-On; Ip, Nancy Yuk Yu

Telomerase Inhibition Studies of Novel Spiroketal-Containing Rubromycin Derivatives

Australian Journal of Chemistry, v. 66, (5), 2013, p. 530-533
Yuen, Tsz-Ying; Ng, Yu-Pong; Ip, Fanny C.F.; Chen, Jack L.Y.; Atkinson, Darcy J.; Sperry, Jonathan; Ip, Nancy Y.; Brimble, Margaret A.

The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics

Journal of Biological Chemistry, v. 288, (27), July 2013, p. 20034-20045
Xiao, Yangui; Peng, Yinghui; Wan, Jun; Tang, Genyun; Chen, Yuewen; Tang, Jing; Ye, Wen-Cai; Ip, Nancy Y.; Shi, Lei
Conference paper 14

Activity-Dependent Phosphorylation of p70 Ribosomal s6 Kinase (p70S6K) by Cdk5 Is Required for Dendritic Spine Maturation


Lai, Kwok On; Fei, Erkang; Ip, Nancy Yuk-Yu

Axin Regulates Dendrite and Spine Development in Hippocampal Neurons


Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu

Cdk5-dependent Phosphorylation of Mst3 Regulates Radial Migration through Modulating RhoA Activity


Tang, Jing; Ip, Jacque Pak Kan; Fang, Weiqun; Zhong, Wanting; Ng, Yu Pong; Wu, Zhenguo; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu

From Understanding Neural Plasticity to Drug Discovery for Neurodegenerative Diseases


Ip, Nancy Yuk-Yu

From Understanding Synaptic Plasticity to Drug Discovery for Neurogenerative Diseases


Ip, Nancy Yuk-Yu

Inhibition of EphA4 Signaling Reverses the Abeta-induced Synaptic Deficits in the Hippocampus


Fu, Amy Kit Yu; Hung, Kwok Wang; Huang, Huiqian; Gu, Shuo; Shen, Yang; Cheng, Elaine; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu

Multidisciplinary Approaches to Combating Brain Disorders


Ip, Nancy Yuk-Yu

Role of Nuclear Cdk5 in Activity-induced Dendrite Development


Liang, Zhuoyi; Chen, Yu; Cai, Y.L.; Lai, Kwok On; Ip, Nancy Yuk-Yu

Small Molecule Antagonist of Prostaglandin E2 Receptor Ameliorates Experimental Autoimmune Encephalomyelitis


Ip, Fanny Chui Fun; Ng, Yu Pong; Ye, W.C.; Ip, Nancy Yuk-Yu

Stem Cell Strategy for Nervous System Disorders


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Undertaking Innovative Research in China: In Search of New Molecular Targets for Alzheimer's Disease


Ip, Nancy Yuk-Yu
Article 11

Ankyrin repeat-rich membrane spanning protein (Kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development

Journal of Neuroscience, v. 32, (24), June 2012, p. 8263-8269
Chen, Yu; Fu, Ada W.Y.; Ip, Pak Kan; Ye, Tao; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Y.

Astragaloside IV and Cycloastragenol Stimulate the Phosphorylation of Extracellular Signal-Regulated Protein Kinase in Multiple Cell Types

Planta Medica, v. 78, (2), January 2012, p. 115-121
Yung, Ying Lisa; Lam, Wing See; Ho, Maurice K.C.; Hu, Sharry Y.; Ip, Fanny C.F.; Pang, Haihong; Chin, Allison; Harley, Calvin B.; Ip, Nancy Yuk-yu; Wong, Yung Hou

Cdk5: a multifaceted kinase in neurodegenerative diseases

Trends in Cell Biology, v. 22, (3), March 2012, p. 169-175
Cheung, Zelda H.; Ip, Nancy Y.

Cyclin-Dependent Kinase 5 in Axon Growth and Regeneration

International Review of Neurobiology, v. 105, December 2012, p. 91-115
Ye, Tao; Fu, Kit Yu; Ip, Nancy Y.

Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons

Experimental Neurology, v.233, (2), 2012, p. 791-798
Huang, Ying; Ko, Ho; Cheung, Zelda H.; Yung, Ken Kin Lam; Yao, Tai; Wang, Jianjun; Morozov, Alexei; Ke, Ya; Ip, Nancy Yuk-yu; Yung, Wingho

Eph receptors at synapses: Implications in neurodegenerative diseases

Cellular Signalling, v. 24, (3), March 2012, p. 606-611
Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu

Guidelines for the use and interpretation of assays for monitoring autophagy

Autophagy, v. 8, (4), 2012, p. 445-544
Klionsky, Daniel J.; Ip, Nancy Yuk-yu

Molecular mechanisms underlying maturation and maintenance of the vertebrate neuromuscular junction

Trends in Neurosciences, v.35, (7), July 2012, p. 441-453
Shi, Ling; Fu, Kit Yu; Ip, Nancy Yuk-yu

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function

Cell Death and Differentiation, v. 19, (2), 2012, p. 257-266
Fitzgerald, J.C.; Camprubi, M.D.; Dunn, L.; Wu, H.C.; Ip, N.Y.; Kruger, R.; Martins, L.M.; Wood, N.W.; Plun-Favreau, H.

TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory

Nature Neuroscience, v.15, (11), 2012, Nov, p. 1506-1515
Lai, Kwok On; Wong, Alan S.L.; Cheung, Man Chun; Xu, Pei; Liang, Zhuoyi; Lok, Ka Chun; Xie, Hui; Palko, Mary E.; Yung, Wing-Ho; Tessarollo, Lino; Cheung, Zelda H.Y.; Ip, Nancy Y.Y.

α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2

Nature Neuroscience, v.15, (1), January 2012, p. 39-47
Ip, Pak Kan; Shi, Lei; Chen, Yu; Itoh, Yasuhiro; Fu, Wing Yu; Betz, Andrea; Yung, Wing-Ho; Gotoh, Yukiko; Fu, Kit Yu; Ip, Nancy Yuk-yu
Book chapter 2

Cyclin-Dependent Kinase 5 – an Emerging Player in Parkinson's Disease Pathophysiology

Mechanisms in Parkinson's Disease - Models and Treatments / Edited by Juliana Dushanova. InTechOpen, 2012, p. 141-156
Cheung, Zelda H.; Ip, Nancy Yuk-Yu

Eph Receptor

Encyclopedia of Signaling Molecules / Edited by Sangdun Choi. Springer International Publishing, 2012, p. 560-567
Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper 19

Axin Regulates the Balance Between Proliferation and Neuronal Differentiation of Neural Precursor Cells


Fang, Weiqun; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu

Cdk5-Dependent Regulation of Rap1 Signaling in Cortical Neuronal Migration


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

CM-Based Drug Discovery for Neurodegenerative Diseases


Ip, Nancy Yuk-Yu

Functional Roles of cdk5 in Rap1 Signaling During Neuronal Migration


Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Functional Roles of Mst3 in Radial Migration During Mouse Cerebral Cortex Development


Tang, J.; Ip, J.P.K.; Fang, W.Q.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Functional Roles of Mst3 in Radial Migration During the Development of Mouse Cerebral Cortex


Tang, Jing; Ip, Pak Kan; Fang, Weiqun; Zhong, Weiting; Ng, Yu Pong; Wu, Zhenguo; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Y.; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity


Shen, Yang; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu

Nucleocytoplasmic Shuttling of Axin Balances Proliferation and Neuronal Differentiation of Neural Progenitor Cells


Fang, W.Q.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

P39-Associated Cdk5 Activity Regulates Dendrite Development


Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

P39-Associated Cdk5 Activity Regulates Dendrite Growth in Neuronal Development


Fu, Amy Kit Yu; Chen, Yu; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu

Role of Cdk5 in Activity-Dependent Dendrite Development and Spine Morphogenesis


Lai, Kwok On; Ip, Nancy Yuk-Yu

Roles of a2-Chimaerin in Neural Circuit Wiring and Function


Fu, Kit Yu; Min, L.; Yung, W.H.; Ip, J.P.K.; Ip, Nancy Yuk-Yu

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) and Its Activator in Neural Development.


Zhang, Peng; Ip, Pak Kan; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) and Its Activator p35 Regulate Neural Development


Zhang, P.; Ip, J.P.K.; Fu, W.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Understanding Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu

Understanding Receptor Tyrosine Kinase-Dependent Signaling in Synaptic Plasticity


Ip, Nancy Yuk-Yu

Α2-Chimaerin Is Required for Proper Functioning of Neural Circuits


Ip, Pak Kan; Yung, Wing Ho; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article 14

A New Carotenoid Glycoside from Rehmannia Glutinosa

Natural Product Research, v.25, (13), August 2011, p. 1213-1218
Fu, Guangmiao; Shi, Shepo; Ip, Fanny C.F.; Pang, Haihong; Ip, Nancy Yuk-yu

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

Nature Neuroscience, v. 14, (2), February 2011, p. 181-191
Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-yu

Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives

Journal of Neurochemistry, v.118, (3), August 2011, p. 317-325
Cheung, Zelda H.; Ip, Nancy Yuk-yu

Career Development for Women Scientists in Asia

Neuron, v. 70, (6), June 2011, p. 1029-1032
Ip, Nancy Y.

Cdk5-Mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development

Journal of Neuroscience, v. 31, (38), September 2011, p. 13613-13624
Fang, Wei-Qun; Ip, Jacque P.K.; Li, Rui; Ng, Yu Pong; Lin, Shengcai; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu

Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

Nature Cell Biology, v. 13, (5), May 2011, p. 568-579
Wong, Alan S.L.; Lee, Rebecca H.K.; Cheung, Anthony Y.; Yeung, Patrick K.; Chung, Sookja K.; Cheung, Zelda H.; Ip, Nancy Yuk-yu

Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development

Neuroscience, v.180, April 2011, p. 353-359
Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-yu

Expression of Gαz in C2C12 Cells Restrains Myogenic Differentiation

Cellular Signalling, v. 23, (2), February 2011, p. 389-397
Mei, Hua; Ho, Kwok Chung Maurice; Yung, Ying; Wu, Zhenguo; Ip, Nancy Yuk-yu; Wong, Yung Hou

From Understanding Synaptic Plasticity to the Development of Cognitive Enhancers

International Journal of Neuropsychopharmacology, v. 14, (9), October 2011, p. 1247-1256
Cheung, Zelda Hiu Yee; Ip, Nancy Yuk-yu

Intestinal Transport of Bis(12)-hupyridone in Caco-2 Cells and its Improved Permeability by the Surfactant Brij-35

Biopharmaceutics & Drug Disposition, v. 32, (3), April 2011, p. 140-150
Yu, Hua; Hu, Yue Qing; Ip, Fanny C.F.; Zuo, Zhong; Han, Yi Fan; Ip, Nancy Yuk-yu

Molecular machinery of macroautophagy and its deregulation in diseases

Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1812, (11), November 2011, p. 1490-1497
Wong, Alan S.L.; Cheung, Zelda H Y; Ip, Nancy Yuk-yu

Natural products targeting telomere maintenance

MedChemComm, v. 2, (4), April 2011, p. 229-245
Chen, Jack Li-Yang; Sperry, Jonathan; Ip, Nancy Y.; Brimble, Margaret A.

Scapinin-induced Inhibition of Axon Elongation Is Attenuated by Phosphorylation and Translocation to the Cytoplasm

Journal of Biological Chemistry, v. 286, (22), June 2011, p. 19724-19734
Farghaian, Hovik; Chen, Yu; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Pak Kan; Ip, Nancy Yuk-yu; Turnley, Ann M.; Cole, Adam R.

Triterpenoids with neurotrophic activity from Ganoderma lucidum

Natural Product Research, v. 25, (17), 2011, p. 1607-1613
Zhang, X.Q.; Ip, Fanny C.F.; Zhang, Dongmei; Chen, Lixin; Zhang, W.; Li, Yaolan; Ip, Nancy Yuk-yu; Ye, Wencai
Conference paper 13

A2-Chimaerin Regulates Crmp-2 Activity to Control Cortical Neuronal Migration


Ip, J.P.; Shi, L.; Itoh, Y.; Fu, Wing Yu; Gotoh, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

Cdk5 Regulates Axon Formation in Cerebral Cortex Through Phosphorylation of Axin


Fu, Kit Yu; Fang,W-Q; Ip, J.P.; Li, R.; Lin,S-C; Chen, Y.; Ip, Nancy Yuk-Yu

EphB Receptor Regulates Glutamatergic Synaptogenesis Through a Cdk5-Dependent Mechanism


Chen, Y.; Wong, H.; Fu, WY; Fu, Kit Yu; Ip, Nancy Yuk-Yu

From Understanding Neural Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu

From Understanding Neural Plasticity to Development of Cognitive Enhancers


Ip, Nancy Yuk-Yu

Functional Roles of Melanocortin-4 Receptor in Synapse Maintenance


Shen, Y.; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu

Functional Roles of Mst3 in Radial Migration During the Development of Mouse Cerebral Cortex


Tang, J.; Ip, J.P.; Shi, L.; Fu, Kit Yu; Ip, Nancy Yuk-Yu

S-Nitrosylation of Cdk5 Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development


Zhang, P.; Yu,P-C; Tsang, A.H.; Chen, Y.; Fu, Kit Yu; Fu, WY; Chung, Kenny Ka Kin; Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu

Understanding the Molecular Basis of Neural Plasticity


Ip, Nancy Yuk-Yu