Faculty Profiles - YANG Liangliang | The Hong Kong University of Science and Technology

Liangliang YANG
楊亮亮

PhD in Organic Chemistry
Nankai University, 2020

Research Assistant Professor
Department of Chemistry

(852) 2358 7376
yangll@ust.hk
Room CYT6014
Personal Web

Google Scholar

OGf7uD0AAAAJ

ORCID

0009-0001-8144-1611

Scopus ID

57766325600

Research Interest Publications Projects Teaching Assignment

Research Interest

Enantioselective reactions
Homogeneous catalysis
Heterocyclic scaffolds
Organic chemistry
Synthetic organic chemistry

Publications

All Years 12 2025 1 2024 2 2023 0 2022 2 2021 4 2020 1 2019 2

2025 1

Enantioselective type II intramolecular [5 + 2] cycloadditions of oxidopyrylium ylides using chiral-phosphoric-acid catalysis

Nature Synthesis, May 2025
Yang, Liangliang; Chan, Ka Lok; Cheung, Ka Key; Chiu, Pauline; Lin, Zhenyang; Sun, Jianwei
Article

2024 2

Catalytic Enantioselective Nucleophilic α-Chlorination of Ketones with NaCl

Journal of the American Chemical Society, v. 146, (4), January 2024, p. 2779-2788
Li, Zhiyang; Wang, Baocheng; Zhang, Chaoshen; Lo, Wai Yam; Yang, Liangliang; Sun, Jianwei
Article

Rhodium-catalyzed enantioselective C−Ge bond formation by carbene insertion: Efficient access to chiral organogermanes

Chem Catalysis, v. 4, (1), January 2024, article number 100826
Han, Ai-Cui; Zhang, Xuan-Ge; Yang, Liangliang; Pan, Jia-Bin; Zou, Hui-Na; Li, Mao-Lin; Xiao, Li-Jun; Zhou, Qi-Lin
Article

2022 2

Ammonia to chiral α-amino acid

Nature Catalysis, v. 5, (6), June 2022, p. 471-472
Yang, Liangliang; Sun, Jianwei
Article

Catalytic Asymmetric Synthesis of Chiral Propargylic Boron Compounds through B-H Bond Insertion Reactions

ACS Catalysis, v. 12, (17), September 2022, p. 10654-10660
Zou, Hui-Na; Zhao, Yu-Tao; Yang, Liangliang; Huang, Ming-Yao; Zhang, Jing-Wei; Huang, Meng-Lin; Zhu, Shou-Fei
Article

2021 4

Chiral Dirhodium Tetraphosphate-Catalyzed Enantioselective Si-H Bond Insertion of α-Aryldiazoacetates

Journal of Organic Chemistry, v. 86, (14), July 2021, p. 9692-9698
Yang, Liangliang; Cao, Jin; Zhao, Tian-Yuan; Zhu, Shou-Fei; Zhou, Qi-Lin
Article

Dirhodium-Catalyzed Enantioselective B−H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

Angewandte Chemie - International Edition, v. 60, (45), November 2021, p. 24214-24219
Zhao, Yu-Tao; Su, Yu-Xuan; Li, Xiao-Yu; Yang, Liangliang; Huang, Ming-Yao; Zhu, Shou-Fei
Article

Enantioselective Insertion of Alkynyl Carbenes into Si-H Bonds: An Efficient Access to Chiral Propargylsilanes and Allenylsilanes

Journal of the American Chemical Society, v. 143, (17), May 2021, p. 6401-6406
Yang, Liangliang; Ouyang, Jing; Zou, Hui-Na; Zhu, Shou-Fei; Zhou, Qi-Lin
Article

Nickel-Catalyzed Desymmetrizing Cyclization of 1,6-Dienes to Construct Quaternary Stereocenters

Organic Letters, v. 23, (10), May 2021, p. 3814-3817
Zhao, Tian-Yuan; Li, Ke; Yang, Liangliang; Zhu, Shou-Fei; Zhou, Qi-Lin
Article

2020 1

Enantioselective Diarylcarbene Insertion into Si-H Bonds Induced by Electronic Properties of the Carbenes

Journal of the American Chemical Society, v. 142, (28), July 2020, p. 12394-12399
Yang, Liangliang; Evans, Declan; Xu, Bin; Li, Wen-Tao; Li, Mao-Lin; Zhu, Shou-Fei; Houk, K.N.; Zhou, Qi-Lin
Article

2017 2

Cinchona Alkaloid Catalyzed Enantioselective [4 + 2] Annulation of Allenic Esters and in Situ Generated ortho-Quinone Methides: Asymmetric Synthesis of Functionalized Chromans

Journal of Organic Chemistry, v. 82, (10), May 2017, p. 5433-5440
Deng, Yu-Hua; Chu, Wen-Dao; Zhang, Xiang-Zhi; Yan, Xu; Yu, Ke-Yin; Yang, Liangliang; Huang, Hanmin; Fan, Chun-An
Article

Mechanism studies of Ir-catalyzed asymmetric hydrogenation of unsaturated carboxylic acids

Journal of the American Chemical Society, v. 139, (1), January 2017, p. 541-547
Li, Mao-Lin; Yang, Shuang; Su, Xun-Cheng; Wu, Hui-Ling; Yang, Liangliang; Zhu, Shou-Fei; Zhou, Qi-Lin
Article

Article 1

Enantioselective type II intramolecular [5 + 2] cycloadditions of oxidopyrylium ylides using chiral-phosphoric-acid catalysis

Nature Synthesis, May 2025
Yang, Liangliang; Chan, Ka Lok; Cheung, Ka Key; Chiu, Pauline; Lin, Zhenyang; Sun, Jianwei

Article 2

Catalytic Enantioselective Nucleophilic α-Chlorination of Ketones with NaCl

Journal of the American Chemical Society, v. 146, (4), January 2024, p. 2779-2788
Li, Zhiyang; Wang, Baocheng; Zhang, Chaoshen; Lo, Wai Yam; Yang, Liangliang; Sun, Jianwei

Rhodium-catalyzed enantioselective C−Ge bond formation by carbene insertion: Efficient access to chiral organogermanes

Chem Catalysis, v. 4, (1), January 2024, article number 100826
Han, Ai-Cui; Zhang, Xuan-Ge; Yang, Liangliang; Pan, Jia-Bin; Zou, Hui-Na; Li, Mao-Lin; Xiao, Li-Jun; Zhou, Qi-Lin

Article 2

Ammonia to chiral α-amino acid

Nature Catalysis, v. 5, (6), June 2022, p. 471-472
Yang, Liangliang; Sun, Jianwei

Catalytic Asymmetric Synthesis of Chiral Propargylic Boron Compounds through B-H Bond Insertion Reactions

ACS Catalysis, v. 12, (17), September 2022, p. 10654-10660
Zou, Hui-Na; Zhao, Yu-Tao; Yang, Liangliang; Huang, Ming-Yao; Zhang, Jing-Wei; Huang, Meng-Lin; Zhu, Shou-Fei

Article 4

Chiral Dirhodium Tetraphosphate-Catalyzed Enantioselective Si-H Bond Insertion of α-Aryldiazoacetates

Journal of Organic Chemistry, v. 86, (14), July 2021, p. 9692-9698
Yang, Liangliang; Cao, Jin; Zhao, Tian-Yuan; Zhu, Shou-Fei; Zhou, Qi-Lin

Dirhodium-Catalyzed Enantioselective B−H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

Angewandte Chemie - International Edition, v. 60, (45), November 2021, p. 24214-24219
Zhao, Yu-Tao; Su, Yu-Xuan; Li, Xiao-Yu; Yang, Liangliang; Huang, Ming-Yao; Zhu, Shou-Fei

Enantioselective Insertion of Alkynyl Carbenes into Si-H Bonds: An Efficient Access to Chiral Propargylsilanes and Allenylsilanes

Journal of the American Chemical Society, v. 143, (17), May 2021, p. 6401-6406
Yang, Liangliang; Ouyang, Jing; Zou, Hui-Na; Zhu, Shou-Fei; Zhou, Qi-Lin

Nickel-Catalyzed Desymmetrizing Cyclization of 1,6-Dienes to Construct Quaternary Stereocenters

Organic Letters, v. 23, (10), May 2021, p. 3814-3817
Zhao, Tian-Yuan; Li, Ke; Yang, Liangliang; Zhu, Shou-Fei; Zhou, Qi-Lin

Article 1

Enantioselective Diarylcarbene Insertion into Si-H Bonds Induced by Electronic Properties of the Carbenes

Journal of the American Chemical Society, v. 142, (28), July 2020, p. 12394-12399
Yang, Liangliang; Evans, Declan; Xu, Bin; Li, Wen-Tao; Li, Mao-Lin; Zhu, Shou-Fei; Houk, K.N.; Zhou, Qi-Lin

Article 2

Cinchona Alkaloid Catalyzed Enantioselective [4 + 2] Annulation of Allenic Esters and in Situ Generated ortho-Quinone Methides: Asymmetric Synthesis of Functionalized Chromans

Journal of Organic Chemistry, v. 82, (10), May 2017, p. 5433-5440
Deng, Yu-Hua; Chu, Wen-Dao; Zhang, Xiang-Zhi; Yan, Xu; Yu, Ke-Yin; Yang, Liangliang; Huang, Hanmin; Fan, Chun-An

Mechanism studies of Ir-catalyzed asymmetric hydrogenation of unsaturated carboxylic acids

Journal of the American Chemical Society, v. 139, (1), January 2017, p. 541-547
Li, Mao-Lin; Yang, Shuang; Su, Xun-Cheng; Wu, Hui-Ling; Yang, Liangliang; Zhu, Shou-Fei; Zhou, Qi-Lin

2017 2

Cinchona Alkaloid Catalyzed Enantioselective [4 + 2] Annulation of Allenic Esters and in Situ Generated ortho-Quinone Methides: Asymmetric Synthesis of Functionalized Chromans

Journal of Organic Chemistry, v. 82, (10), May 2017, p. 5433-5440
Deng, Yu-Hua; Chu, Wen-Dao; Zhang, Xiang-Zhi; Yan, Xu; Yu, Ke-Yin; Yang, Liangliang; Huang, Hanmin; Fan, Chun-An
Article

Mechanism studies of Ir-catalyzed asymmetric hydrogenation of unsaturated carboxylic acids

Journal of the American Chemical Society, v. 139, (1), January 2017, p. 541-547
Li, Mao-Lin; Yang, Shuang; Su, Xun-Cheng; Wu, Hui-Ling; Yang, Liangliang; Zhu, Shou-Fei; Zhou, Qi-Lin
Article

No Publications

Teaching Assignment

2024-25 Spring 1 2024-25 Winter 0 2024-25 Fall 0 2023-24 Summer 0 2023-24 Spring 0 2023-24 Winter 0

CHEM4689

Capstone Project

No Teaching Assignments

Projects

From January 2023 to December 2025

All Projects 1

No Projects.
Development of New Asymmetric Reactions

新型有機不對稱反應的發展 Participating

China National Postdoctoral Council under the Ministry of Human Resources and Social Security
Project Team (HKUST)
SUN Jianwei (Lead)

YANG Liangliang
2021 - 2023

Research Interest

Publications

2025 1

2024 2

2022 2

2021 4

2020 1

2017 2

Article 1

Article 2

Article 2

Article 4

Article 1

Article 2

2017 2

Teaching Assignment

Projects

From January 2023 to December 2025

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