Faculty Profiles - HUANG Jinqing | The Hong Kong University of Science and Technology

Jinqing HUANG
黃晉卿

PhD in Physical Chemistry
The University of Hong Kong, 2015

Associate Professor
Department of Chemistry

(852) 3469 2627
jqhuang@ust.hk
Room 4544
Personal Web

Google Scholar

AzZLMCsAAAAJ

ORCID

0000-0001-6865-8528

Scopus ID

56135622500

Research Interest Publications Projects Teaching Assignment RPG Supervision Space used

Research Interest

Single molecule manipulation
Raman spectroscopy
Protein folding
Biophysical chemistry

Publications

All Years 60 2025 0 2024 18 2023 7 2022 14 2021 5 2020 5 2019 11

2024 18

Additional label-free chemical resolution to single-molecule force spectroscopy

Biophysical Journal, v. 123, (3), February 2024, p. 448a-449a, Supplement 1
Huang, Jinqing
Article

Antibiofilm and pH-responsive properties of nature-derived mucin biomaterials and their potentials for chronic wound care

Matter, v. 7, (12), December 2024, p. 4356-4372
Feng, Xianzhen; Zhang, Jianing; Rodriguez Serrano, Alan Fernando; Huang, Jinqing; Hsing, I-ming
Article

Differential effects of SARS-CoV-2 amyloidogenic segments on the aggregation and toxicity of human islet amyloid polypeptide within membrane environments

International Journal of Biological Macromolecules, v. 283, December 2024, article number 137930
Zhang, Jianing; Mesias, Vince St. Dollente; Chesney, Andrew D.; Anand, Vignesh K.; Feng, Xianzhen; Hsing, I-Ming; Hansmann, Ulrich H.E.; Huang, Jinqing
Article

Distinct Effects of SARS-CoV-2 Protein Segments on Structural Stability, Amyloidogenic Potential, and α-Synuclein Aggregation

ChemBioChem, v. 25, (24), 2024, article number e202400598
Mesias, Vince St. Dollente; Zhang, Jianing; Zhu, Hongni; Dai, Xin; Li, Jixi; Huang, Jinqing
Article

Dynamic conformational changes of a tardigrade group-3 late embryogenesis abundant protein modulate membrane biophysical properties

PNAS Nexus, v. 3, (1), January 2024, article number pgae006
Li, Xiao-Han; Yu, Conny W.H.; Gomez-Navarro, Natalia; Stancheva, Viktoriya; Zhu, Hongni; Murthy, Andal; Wozny, Michael; Malhotra, Ketan; Johnson, Christopher M.; Blackledge, Martin; Santhanam, Balaji; Liu, Wei; Huang, Jinqing; Freund, Stefan M. V.; Miller, Elizabeth A.; Babu, M Madan
Article

Intense NIR-II luminescence through stabilization of tetrahedral (Mn⁵⁺O₄) lumophore in apatites with high external quantum efficiency

Acta Materialia, v. 273, July 2024, article number 119981
Huang, Wenjing; Zhang, Jiahui; Fan, Jiaqi; Zhang, Jilin; Huang, Jinqing; Chen, Peican; Zhou, Liya; Zhang, Xinguo
Article

Metastable biological matter in liquid phase separation

Applied Research, v. 3, (2), April 2024, article number e202300071
Liu, Jianhui; Liu, Xiaolin; Zhang, Tianfu; Huang, Jinqing; Tang, Benzhong; Chau, Ying
Article

Novel solution and solid-state emissive long-wavelength carbon dots for water sensing and white LED applications

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, v. 304, January 2024, article number 123328
Zhou, Weiying; Sun, Zishan; Fan, Jiaqi; Huang, Wenjing; Zhang, Jiahui; Song, Hongji; Zhou, Liya; Huang, Jinqing; Wu, Zhan-chao; Zhang, Xinguo
Article

Red-Shifting B₁₂-Dependent Photoreceptor Protein via Optical Coupling for Inducible Living Materials

Angewandte Chemie-International Edition, v. 63, (50), December 2024, article number e202411105
Fok, Hong Kiu Francis; Dai, Xin; Yi, Qikun; Che, Chi Ming; Jiang, Lingxiang; Duan, Liting; Huang, Jinqing; Yang, Zhongguang; Sun, Fei
Article

Two-photon fluorescence-guided precise photothermal therapy located in a single cancer cell utilizing bifunctional N-doped carbon quantum dots

Journal of Colloid and Interface Science, v. 662, May 2024, p. 719-726
Li, Dan; Huang, Kai; She, Jiahong; Cai, Yuying; Liu, Boyuan; Wei, Zhongchao; Chen, Yibo; Huang, Jinqing; Fan, Haihua
Article

Water-Vapor-Triggered Dual-Mode Optical Responses in Rare-Earth-Doped Hollow Nanospheres

Nano Letters, v. 24, (47), November 2024, p. 15001-15007
Huang, Hongji; Chen, Zixian; Zheng, Hanqi; Ou, Yingyi; Zhang, Jianing; Xiao, Kang; Huang, Jinqing; Liu, Zhao-Qing; Chen, Yibo
Article

ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction

Cell Death and Disease, v. 15, (7), July 2024, article number 487, p. 1-10
Xie, Feiyan; Wu, Di; Huang, Jing; Liu, Xuehe; Shen, Yanfang; Huang, Jinqing; Su, Zhipeng; Li, Jixi
Article

Active characterizations of biological macromolecules at the single-molecule level by optical tweezers-coupled Raman spectroscopy

Huang, Jinqing
Conference paper

Additional label-free chemical resolution to single-molecule force spectroscopy

Huang, Jinqing
Conference paper

Dynamic and controllable characterization of biological macromolecules at a single-molecule level using optical tweezers-coupled Raman spectroscopy

Huang, Jinqing
Conference paper

Dynamic and controllable characterization of biological macromolecules at the single-molecule level using optical tweezers-coupled Raman spectroscopy

Huang, Jinqing
Conference paper

Dynamic and Controllable Characterization of Biological Macromolecules at the Single-Molecule Level using Optical Tweezers-Coupled Raman Spectroscopy

Huang, Jinqing
Conference paper

Site-specific DNA-metal complex interactions studied by single-molecule force coupled surface-enhanced Raman spectroscopy (SERS)

Huang, Jinqing
Conference paper

2023 7

Construction of Multiphasic Membraneless Organelles towards Spontaneous Spatial Segregation and Directional Flow of Biochemical Reactions

Chemical Science, v. 14, (4), January 2023, p. 801-811
Zhorabek, Fariza; Abesekara, Manisha Sandupama; Liu, Jianhui; Dai, Xin; Huang, Jinqing; Chau, Ying
Article

Efficient optical plasmonic tweezer-controlled single-molecule SERS characterization of pH-dependent amylin species in aqueous milieus

Nature Communications, v. 14, (1), November 2023, article number 6996
Fu, Wenhao; Chi, Huanyu; Dai, Xin; Zhu, Hongni; Mesias, Vince St. Dollente; Liu, Wei; Huang, Jinqing
Article

Flexible Hf₆Ta₂O₁₇@ acidified carbon nanotube composite films with enhanced interfacial interaction for high-performance supercapacitors

Ceramics International, v. 49, (13), July 2023, p. 22089-22099
Xue, Yufeng; Ruan, Piao; Zhu, Li; Cao, Yi; Fu, Wenhao; Huang, Jinqing; Qiu, Wenfeng
Article

Single-molecule force manipulation facilitated multiple rereads of a drug-bound DNA at specified sites by surface-enhanced Raman spectroscopy

Biophysical Journal, v. 122, (3, Supplement 1), February 2023, p. 429a
Huang, Jinqing
Article

Synthesis and luminescent properties of ZnWO₄: Cr³⁺ nanoparticles for NIR-II fluorescence imaging

Ceramics International, v. 49, (15), August 2023, p. 25682-25688
Xiao, Qiang; Zhou, Weiying; Fan, Jiaqi; Zhou, Liya; Chen, Peican; Mo, Fowang; Huang, Jinqing; Liu, Xiang; Zhang, Xinguo
Article

Tunable lipid-coated nanoporous silver sheet for characterization of protein-membrane interactions by surface-enhanced Raman scattering (SERS)

Analytical and Bioanalytical Chemistry, v. 415, (16), April 2023, p. 3243-3253
Zhu, Hongni; Zhang, Jianing; Dai, Xin; Mesias, Vince St. Dollente; Chi, Huanyu; Wang, Congcheng; Yeung, Chi Shun; Chen, Qing; Liu, Wei; Huang, Jinqing
Article

Single-molecule force manipulation facilitated multiple rereads of a drug-bound DNA at specified sites by surface-enhanced Raman spectroscopy

Huang, Jinqing
Conference paper

2022 14

A SURF4-to-Proteoglycan Relay Mechanism that Mediates the Sorting and Secretion of a Tagged Variant of Sonic Hedgehog

Proceedings of the National Academy of Sciences of the United States of America, v. 119, (11), March 2022, article number e2113991119
Tang, Xiao; Chen, Rong; Mesias, Vince St. Dollente; Wang, Tingxuan; Wang, Ying; Poljak, Kristina; Fan, Xinyu; Miao, Hanchi; Hu, Junjie; Zhang, Liang; Huang, Jinqing; Yao, Shuhuai; Miller, Elizabeth A.; Guo, Yusong
Article

Bright Red-Emitting P, Br Co-Doped Carbon Dots as “OFF-ON” Fluorescent Probe for Cu²⁺ and L-cysteine Detection

Journal of Alloys and Compounds, v. 897, March 2022, article number 162731
Zhou, Weiying; Mo, Fuwang; Sun, Zishan; Luo, Jiabao; Fan, Jiaqi; Zhu, Hongni; Zhu, Zhenpeng; Huang, Jinqing; Zhang, Xinguo
Article

Combing force manipulation and Raman spectroscopy characterization to study protein structures

Biophysical Journal, v. 121, (3), February 2022, p. 3a, Supplement 1
Huang, Jinqing
Article

Controlling synthetic membraneless organelles by a red-light-dependent singlet oxygen-generating protein

Nature Communications, v. 13, (1), June 2022, article number 3197
Li, Manjia; Park, Byung Min; Dai, Xin; Xu, Yingjie; Huang, Jinqing; Sun, Fei
Article

Directed assembly of genetically engineered eukaryotic cells into living functional materials via ultrahigh-affinity protein interactions

Science Advances, v. 8, (44), 4 November 2022, article number eade0073
Yi, Qikun; Dai, Xin; Park, Byung Min; Gu, Junhao; Luo, Jiren; Wang, Ri; Yu, Cong; Kou, Songzi; Huang, Jinqing; Lakerveld, Richard; Sun, Fei
Article

High-efficient and pH-sensitive orange luminescence from silicon-doped carbon dots for information encryption and bio-imaging

Journal of Colloid and Interface Science, v. 607, (Part 1), February 2022, p. 16-23
Sun, Zishan; Zhou, Weiying; Luo, Jiabao; Fan, Jiaqi; Wu, Zhan-chao; Zhu, Hongni; Huang, Jinqing; Zhang, Xinguo
Article

Minimalist Design of an Intrinsically Disordered Protein-Mimicking Scaffold for an Artificial Membraneless Organelle

ACS Central Science, v. 8, (4), April 2022, p. 493-500
Liu, Jianhui; Zhorabek, Fariza; Dai, Xin; Huang, Jinqing; Chau, Ying
Article

Moderate Binding between Two SARS-CoV-2 Protein Segments and α-Synuclein Alters Its Toxic Oligomerization Propensity Differently

The Journal of Physical Chemistry Letters, v. 13, (45), November 2022, p. 10642-10648
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Liu, Wei; Guo, Yusong; Huang, Jinqing
Article

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Journal of Visualized Experiments, v. 2022, (184), June 2022, article number e63862
Dai, Xin; Qiu, Wenting; Huang, Jinqing
Article

Protein purification, crystallization, and structure determination of human DEAD-box RNA helicase DDX21 in different unwinding states

STAR Protocols, v. 3, (3), 16 September 2022, article number 101642
Chen, Zijun; Huang, Jinqing; Li, Jixi
Article

Red-emitting carbon dots as luminescent agent in wide-range water detection in organic solvents and polarity-selective zebrafish imaging

Journal of Alloys and Compounds, v. 920, 5 November 2022, article number 165963
Zhou, Weiying; Liu, Chuang; Fan, Jiaqi; Luo, Jiabao; Liu, Lihong; Huang, Jinqing; Liu, Ruiyuan; Zhang, Xinguo
Article

Combing force manipulation and Raman spectroscopy characterization to study protein structures

Huang, Jinqing
Conference paper

Efficient separation and characterization of biomolecules by optical tweezers-controlled surface-enhanced Raman spectroscopy

Huang, Jinqing
Conference paper

Manipulation and characterization of biomolecule-metal complex interaction at the single-molecule level

Huang, Jinqing
Conference paper

2021 5

Effective ACE2 peptide-nanoparticle conjugation and its binding with the SARS-Cov-2 RBD quantified by dynamic light scattering

Chemical Communications, v. 57, (57), July 2021, p. 6979-6982
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing
Article

Insights into unexpected photoisomerization from photooxidation of tribromoacetic acid in aqueous environment using ultrafast spectroscopy

Journal of Hazardous Materials, v. 418, September 2021, article number 126214
Yeung, Chi Shun; Tse, Ho Yin; Lau, Chun Yin; Guan, Jianyu; Huang, Jinqing; Phillips, David Lee; Leu, Shao-Yuan
Article

Optical tweezers-controlled hotspot for sensitive and reproducible surface-enhanced Raman spectroscopy characterization of native protein structures

Nature Communications, v. 12, (1), February 2021, article number 1292
Dai, Xin; Fu, Wenhao; Chi, Huanyu; Mesias, Vince St. Dollente; Zhu, Hongni; Leung, Cheuk Wai; Liu, Wei; Huang, Jinqing
Article

Combining optical tweezers microscopy and surface-enhanced Raman spectroscopy (SERS) to characterize protein structures

Huang, Jinqing
Conference paper

Truncated Angiotensin-Converting Enzyme-2 peptide conjugated nanoparticles as an efficient, specific, and long-lasting antiviral platform for SARS-CoV-2

Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing
Conference paper

2020 5

Highly reusable nanoporous silver sheet for sensitive SERS detection of pesticides

Analyst, v. 145, (15), August 2020, p. 5158-5165
Chi, Huanyu; Wang, Congcheng; Wang, Zhien; Zhu, Hongni; Mesias, Vince St. Dollente; Dai, Xin; Chen, Qing; Liu, Wei; Huang, Jinqing
Article

Single-Molecule Mechanical Unfolding of AT-Rich Chromosomal Fragile Site DNA Hairpins: Resolving the Thermodynamic and Kinetic Effects of a Single G-T Mismatch

The Journal of Physical Chemistry. B, v. 124, (42), 22 October 2020, p. 9365-9370
Li, Xiong; Pei, Yufeng; Zhang, Yashuo; Liu, Yajun; Fu, Wenhao; Li, Jixi; You, Huijuan; Huang, Jinqing
Article

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation

Advanced Science, 2020
Huang, Jinqing
Article

DNA‑Pt complex interactions investigated by single‑molecule force spectroscopy and surface‑enhanced Raman spectroscopy

Dai, Xin; Li, Xiong; Leung, Cheuk Wai; Zhu, Hongni; Huang, Jinqing
Conference paper

Octave-spanning mid-infrared pulses for ultrafast temporal resolution in single-molecule manipulations and characterizations

Huang, Jinqing
Conference paper

2017 1

A spectroscopic study of the excited state proton transfer processes of (8-bromo-7-hydroxyquinolin-2-yl)methyl-protected phenol in aqueous solutions

Photochemical and Photobiological Sciences, v. 16, (4), April 2017, p. 575-584
Huang, Jinqing; Muliawan, Adna P.; Ma, Jiani; Li, Mingde; Chiu, Hoikei; Lan, Xin; Deodato, Davide; Phillips, David Lee; Dore, Timothy M.
Article

2016 2

Octave-spanning mid-infrared pulses by plasma generation in air pumped with an Yb:KGW source

Optics Letters, v. 41, (21), November 2016, p. 4855-4858
Huang, Jinqing; Alexander Parobek; Ziad Ganim
Article

Substituent Effects on the Photodeprotection Reactions of Selected Ketoprofen Derivatives in Phosphate Buffered Aqueous Solutions

Scientific Reports, v. 6, February 2016, article number 21606
Liu, Mingyue; Li, Mingde; Huang, Jinqing; Li, Tianlu; Liu, Han; Li, Xuechen; Phillips, David Lee
Article

2015 2

How Does the C–Halogen Bond Break in the Photosubstitution Reaction of 3-Fluorobenzophenone in Acidic Aqueous Solutions?

Journal of Organic Chemistry, v. 80, (19), October 2015, p. 9425-9436
Huang, Jinqing; Ma, Jiani; Li, Mingde; Liu, Mingyue; Zhang, Xiting; Phillips, David Lee
Article

Investigation of the Role of Protonation of Benzophenone and Its Derivatives in Acidic Aqueous Solutions Using Time-Resolved Resonance Raman Spectroscopy: How Are Ketyl Radicals Formed in Aqueous Solutions?

Journal of Physical Chemistry B, v. 119, (6), February 2015, p. 2241-2252
Li, Mingde; Huang, Jinqing; Liu, Mingyue; Li, Songbo; Ma, Jiani; Phillips, David Lee
Article

2014 2

A Computational Chemistry Investigation of the Mechanism of the Water-Assisted Decomposition of Trichloroethylene Oxide

Journal of Physical Chemistry A, v. 118, (9), March 2014, p. 1557-1567
Huang, Jinqing; Yeung, Chishun; Ma, Jiani; Gayner, Emma R.; Phillips, David Lee
Article

Direct Time-Resolved Spectroscopic Observation of Arylnitrenium Ion Reactions with Guanine-Containing DNA Oligomers

Journal of Organic Chemistry, v. 79, (8), April 2014, p. 3610-3614
Xue, Jiadan; Du, Lili; Zhu, Ruixue; Huang, Jinqing; Phillips, David Lee
Article

2013 1

Meta Versus Para Substitution: How Does C–H Activation in a Methyl Group Occur in 3-Methylbenzophenone but Does Not Take Place in 4-Methylbenzophenone?

Journal of Organic Chemistry, v. 78, (10), May 2013, p. 4867-4878
Ma, Jiani; Su, Tao; Li, Mingde; Zhang, Xiting; Huang, Jinqing; Phillips, David Lee
Article

2012 1

How and When Does an Unusual and Efficient Photoredox Reaction of 2-(1-Hydroxyethyl) 9,10-Anthraquinone Occur? A Combined Time-Resolved Spectroscopic and DFT Study

Journal of the American Chemical Society, v. 134, (36), September 2012, p. 14858-14868
Ma, Jiani; Su, Tao; Li, Mingde; Du, Wei; Huang, Jinqing; Guan, Xiangguo; Phillips, David Lee
Article

2010 1

Synthesis and luminescence of Eu²⁺-doped alkaline-earth apatites for application in white LED

Journal of Luminescence, v. 130, (4), April 2010, p. 554-559
Zhang, Xinguo; Zhang, Jilin; Huang, Jinqing; Tang, Xueping; Gong, Menglian
Article

2009 1

Near UV-based LED fabricated with Ba₅SiO₄(F,Cl)₆:Eu²⁺ as blue- and green-emitting phosphor

Optical Materials, v. 32, (1), November 2009, p. 75-78
Zhang, Xinguo; Wang, Xiaoxiao; Huang, Jinqing; Shi, Jinxin; Gong, Menglian
Article

Article 12

Additional label-free chemical resolution to single-molecule force spectroscopy

Biophysical Journal, v. 123, (3), February 2024, p. 448a-449a, Supplement 1
Huang, Jinqing

Antibiofilm and pH-responsive properties of nature-derived mucin biomaterials and their potentials for chronic wound care

Matter, v. 7, (12), December 2024, p. 4356-4372
Feng, Xianzhen; Zhang, Jianing; Rodriguez Serrano, Alan Fernando; Huang, Jinqing; Hsing, I-ming

Differential effects of SARS-CoV-2 amyloidogenic segments on the aggregation and toxicity of human islet amyloid polypeptide within membrane environments

International Journal of Biological Macromolecules, v. 283, December 2024, article number 137930
Zhang, Jianing; Mesias, Vince St. Dollente; Chesney, Andrew D.; Anand, Vignesh K.; Feng, Xianzhen; Hsing, I-Ming; Hansmann, Ulrich H.E.; Huang, Jinqing

Distinct Effects of SARS-CoV-2 Protein Segments on Structural Stability, Amyloidogenic Potential, and α-Synuclein Aggregation

ChemBioChem, v. 25, (24), 2024, article number e202400598
Mesias, Vince St. Dollente; Zhang, Jianing; Zhu, Hongni; Dai, Xin; Li, Jixi; Huang, Jinqing

Dynamic conformational changes of a tardigrade group-3 late embryogenesis abundant protein modulate membrane biophysical properties

PNAS Nexus, v. 3, (1), January 2024, article number pgae006
Li, Xiao-Han; Yu, Conny W.H.; Gomez-Navarro, Natalia; Stancheva, Viktoriya; Zhu, Hongni; Murthy, Andal; Wozny, Michael; Malhotra, Ketan; Johnson, Christopher M.; Blackledge, Martin; Santhanam, Balaji; Liu, Wei; Huang, Jinqing; Freund, Stefan M. V.; Miller, Elizabeth A.; Babu, M Madan

Intense NIR-II luminescence through stabilization of tetrahedral (Mn⁵⁺O₄) lumophore in apatites with high external quantum efficiency

Acta Materialia, v. 273, July 2024, article number 119981
Huang, Wenjing; Zhang, Jiahui; Fan, Jiaqi; Zhang, Jilin; Huang, Jinqing; Chen, Peican; Zhou, Liya; Zhang, Xinguo

Metastable biological matter in liquid phase separation

Applied Research, v. 3, (2), April 2024, article number e202300071
Liu, Jianhui; Liu, Xiaolin; Zhang, Tianfu; Huang, Jinqing; Tang, Benzhong; Chau, Ying

Novel solution and solid-state emissive long-wavelength carbon dots for water sensing and white LED applications

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, v. 304, January 2024, article number 123328
Zhou, Weiying; Sun, Zishan; Fan, Jiaqi; Huang, Wenjing; Zhang, Jiahui; Song, Hongji; Zhou, Liya; Huang, Jinqing; Wu, Zhan-chao; Zhang, Xinguo

Red-Shifting B₁₂-Dependent Photoreceptor Protein via Optical Coupling for Inducible Living Materials

Angewandte Chemie-International Edition, v. 63, (50), December 2024, article number e202411105
Fok, Hong Kiu Francis; Dai, Xin; Yi, Qikun; Che, Chi Ming; Jiang, Lingxiang; Duan, Liting; Huang, Jinqing; Yang, Zhongguang; Sun, Fei

Two-photon fluorescence-guided precise photothermal therapy located in a single cancer cell utilizing bifunctional N-doped carbon quantum dots

Journal of Colloid and Interface Science, v. 662, May 2024, p. 719-726
Li, Dan; Huang, Kai; She, Jiahong; Cai, Yuying; Liu, Boyuan; Wei, Zhongchao; Chen, Yibo; Huang, Jinqing; Fan, Haihua

Water-Vapor-Triggered Dual-Mode Optical Responses in Rare-Earth-Doped Hollow Nanospheres

Nano Letters, v. 24, (47), November 2024, p. 15001-15007
Huang, Hongji; Chen, Zixian; Zheng, Hanqi; Ou, Yingyi; Zhang, Jianing; Xiao, Kang; Huang, Jinqing; Liu, Zhao-Qing; Chen, Yibo

ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction

Cell Death and Disease, v. 15, (7), July 2024, article number 487, p. 1-10
Xie, Feiyan; Wu, Di; Huang, Jing; Liu, Xuehe; Shen, Yanfang; Huang, Jinqing; Su, Zhipeng; Li, Jixi

Conference paper 6

Active characterizations of biological macromolecules at the single-molecule level by optical tweezers-coupled Raman spectroscopy

Huang, Jinqing

Additional label-free chemical resolution to single-molecule force spectroscopy

Huang, Jinqing

Dynamic and controllable characterization of biological macromolecules at a single-molecule level using optical tweezers-coupled Raman spectroscopy

Huang, Jinqing

Dynamic and controllable characterization of biological macromolecules at the single-molecule level using optical tweezers-coupled Raman spectroscopy

Huang, Jinqing

Dynamic and Controllable Characterization of Biological Macromolecules at the Single-Molecule Level using Optical Tweezers-Coupled Raman Spectroscopy

Huang, Jinqing

Site-specific DNA-metal complex interactions studied by single-molecule force coupled surface-enhanced Raman spectroscopy (SERS)

Huang, Jinqing

Article 6

Construction of Multiphasic Membraneless Organelles towards Spontaneous Spatial Segregation and Directional Flow of Biochemical Reactions

Chemical Science, v. 14, (4), January 2023, p. 801-811
Zhorabek, Fariza; Abesekara, Manisha Sandupama; Liu, Jianhui; Dai, Xin; Huang, Jinqing; Chau, Ying

Efficient optical plasmonic tweezer-controlled single-molecule SERS characterization of pH-dependent amylin species in aqueous milieus

Nature Communications, v. 14, (1), November 2023, article number 6996
Fu, Wenhao; Chi, Huanyu; Dai, Xin; Zhu, Hongni; Mesias, Vince St. Dollente; Liu, Wei; Huang, Jinqing

Flexible Hf₆Ta₂O₁₇@ acidified carbon nanotube composite films with enhanced interfacial interaction for high-performance supercapacitors

Ceramics International, v. 49, (13), July 2023, p. 22089-22099
Xue, Yufeng; Ruan, Piao; Zhu, Li; Cao, Yi; Fu, Wenhao; Huang, Jinqing; Qiu, Wenfeng

Single-molecule force manipulation facilitated multiple rereads of a drug-bound DNA at specified sites by surface-enhanced Raman spectroscopy

Biophysical Journal, v. 122, (3, Supplement 1), February 2023, p. 429a
Huang, Jinqing

Synthesis and luminescent properties of ZnWO₄: Cr³⁺ nanoparticles for NIR-II fluorescence imaging

Ceramics International, v. 49, (15), August 2023, p. 25682-25688
Xiao, Qiang; Zhou, Weiying; Fan, Jiaqi; Zhou, Liya; Chen, Peican; Mo, Fowang; Huang, Jinqing; Liu, Xiang; Zhang, Xinguo

Tunable lipid-coated nanoporous silver sheet for characterization of protein-membrane interactions by surface-enhanced Raman scattering (SERS)

Analytical and Bioanalytical Chemistry, v. 415, (16), April 2023, p. 3243-3253
Zhu, Hongni; Zhang, Jianing; Dai, Xin; Mesias, Vince St. Dollente; Chi, Huanyu; Wang, Congcheng; Yeung, Chi Shun; Chen, Qing; Liu, Wei; Huang, Jinqing

Conference paper 1

Single-molecule force manipulation facilitated multiple rereads of a drug-bound DNA at specified sites by surface-enhanced Raman spectroscopy

Huang, Jinqing

Article 11

A SURF4-to-Proteoglycan Relay Mechanism that Mediates the Sorting and Secretion of a Tagged Variant of Sonic Hedgehog

Proceedings of the National Academy of Sciences of the United States of America, v. 119, (11), March 2022, article number e2113991119
Tang, Xiao; Chen, Rong; Mesias, Vince St. Dollente; Wang, Tingxuan; Wang, Ying; Poljak, Kristina; Fan, Xinyu; Miao, Hanchi; Hu, Junjie; Zhang, Liang; Huang, Jinqing; Yao, Shuhuai; Miller, Elizabeth A.; Guo, Yusong

Bright Red-Emitting P, Br Co-Doped Carbon Dots as “OFF-ON” Fluorescent Probe for Cu²⁺ and L-cysteine Detection

Journal of Alloys and Compounds, v. 897, March 2022, article number 162731
Zhou, Weiying; Mo, Fuwang; Sun, Zishan; Luo, Jiabao; Fan, Jiaqi; Zhu, Hongni; Zhu, Zhenpeng; Huang, Jinqing; Zhang, Xinguo

Combing force manipulation and Raman spectroscopy characterization to study protein structures

Biophysical Journal, v. 121, (3), February 2022, p. 3a, Supplement 1
Huang, Jinqing

Controlling synthetic membraneless organelles by a red-light-dependent singlet oxygen-generating protein

Nature Communications, v. 13, (1), June 2022, article number 3197
Li, Manjia; Park, Byung Min; Dai, Xin; Xu, Yingjie; Huang, Jinqing; Sun, Fei

Directed assembly of genetically engineered eukaryotic cells into living functional materials via ultrahigh-affinity protein interactions

Science Advances, v. 8, (44), 4 November 2022, article number eade0073
Yi, Qikun; Dai, Xin; Park, Byung Min; Gu, Junhao; Luo, Jiren; Wang, Ri; Yu, Cong; Kou, Songzi; Huang, Jinqing; Lakerveld, Richard; Sun, Fei

High-efficient and pH-sensitive orange luminescence from silicon-doped carbon dots for information encryption and bio-imaging

Journal of Colloid and Interface Science, v. 607, (Part 1), February 2022, p. 16-23
Sun, Zishan; Zhou, Weiying; Luo, Jiabao; Fan, Jiaqi; Wu, Zhan-chao; Zhu, Hongni; Huang, Jinqing; Zhang, Xinguo

Minimalist Design of an Intrinsically Disordered Protein-Mimicking Scaffold for an Artificial Membraneless Organelle

ACS Central Science, v. 8, (4), April 2022, p. 493-500
Liu, Jianhui; Zhorabek, Fariza; Dai, Xin; Huang, Jinqing; Chau, Ying

Moderate Binding between Two SARS-CoV-2 Protein Segments and α-Synuclein Alters Its Toxic Oligomerization Propensity Differently

The Journal of Physical Chemistry Letters, v. 13, (45), November 2022, p. 10642-10648
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Liu, Wei; Guo, Yusong; Huang, Jinqing

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Journal of Visualized Experiments, v. 2022, (184), June 2022, article number e63862
Dai, Xin; Qiu, Wenting; Huang, Jinqing

Protein purification, crystallization, and structure determination of human DEAD-box RNA helicase DDX21 in different unwinding states

STAR Protocols, v. 3, (3), 16 September 2022, article number 101642
Chen, Zijun; Huang, Jinqing; Li, Jixi

Red-emitting carbon dots as luminescent agent in wide-range water detection in organic solvents and polarity-selective zebrafish imaging

Journal of Alloys and Compounds, v. 920, 5 November 2022, article number 165963
Zhou, Weiying; Liu, Chuang; Fan, Jiaqi; Luo, Jiabao; Liu, Lihong; Huang, Jinqing; Liu, Ruiyuan; Zhang, Xinguo

Conference paper 3

Combing force manipulation and Raman spectroscopy characterization to study protein structures

Huang, Jinqing

Efficient separation and characterization of biomolecules by optical tweezers-controlled surface-enhanced Raman spectroscopy

Huang, Jinqing

Manipulation and characterization of biomolecule-metal complex interaction at the single-molecule level

Huang, Jinqing

Article 3

Effective ACE2 peptide-nanoparticle conjugation and its binding with the SARS-Cov-2 RBD quantified by dynamic light scattering

Chemical Communications, v. 57, (57), July 2021, p. 6979-6982
Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing

Insights into unexpected photoisomerization from photooxidation of tribromoacetic acid in aqueous environment using ultrafast spectroscopy

Journal of Hazardous Materials, v. 418, September 2021, article number 126214
Yeung, Chi Shun; Tse, Ho Yin; Lau, Chun Yin; Guan, Jianyu; Huang, Jinqing; Phillips, David Lee; Leu, Shao-Yuan

Optical tweezers-controlled hotspot for sensitive and reproducible surface-enhanced Raman spectroscopy characterization of native protein structures

Nature Communications, v. 12, (1), February 2021, article number 1292
Dai, Xin; Fu, Wenhao; Chi, Huanyu; Mesias, Vince St. Dollente; Zhu, Hongni; Leung, Cheuk Wai; Liu, Wei; Huang, Jinqing

Conference paper 2

Combining optical tweezers microscopy and surface-enhanced Raman spectroscopy (SERS) to characterize protein structures

Huang, Jinqing

Truncated Angiotensin-Converting Enzyme-2 peptide conjugated nanoparticles as an efficient, specific, and long-lasting antiviral platform for SARS-CoV-2

Mesias, Vince St. Dollente; Zhu, Hongni; Tang, Xiao; Dai, Xin; Guo, Yusong; Liu, Wei; Huang, Jinqing

Article 3

Highly reusable nanoporous silver sheet for sensitive SERS detection of pesticides

Analyst, v. 145, (15), August 2020, p. 5158-5165
Chi, Huanyu; Wang, Congcheng; Wang, Zhien; Zhu, Hongni; Mesias, Vince St. Dollente; Dai, Xin; Chen, Qing; Liu, Wei; Huang, Jinqing

Single-Molecule Mechanical Unfolding of AT-Rich Chromosomal Fragile Site DNA Hairpins: Resolving the Thermodynamic and Kinetic Effects of a Single G-T Mismatch

The Journal of Physical Chemistry. B, v. 124, (42), 22 October 2020, p. 9365-9370
Li, Xiong; Pei, Yufeng; Zhang, Yashuo; Liu, Yajun; Fu, Wenhao; Li, Jixi; You, Huijuan; Huang, Jinqing

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation

Advanced Science, 2020
Huang, Jinqing

Conference paper 2

DNA‑Pt complex interactions investigated by single‑molecule force spectroscopy and surface‑enhanced Raman spectroscopy

Dai, Xin; Li, Xiong; Leung, Cheuk Wai; Zhu, Hongni; Huang, Jinqing

Octave-spanning mid-infrared pulses for ultrafast temporal resolution in single-molecule manipulations and characterizations

Huang, Jinqing

Article 1

A spectroscopic study of the excited state proton transfer processes of (8-bromo-7-hydroxyquinolin-2-yl)methyl-protected phenol in aqueous solutions

Photochemical and Photobiological Sciences, v. 16, (4), April 2017, p. 575-584
Huang, Jinqing; Muliawan, Adna P.; Ma, Jiani; Li, Mingde; Chiu, Hoikei; Lan, Xin; Deodato, Davide; Phillips, David Lee; Dore, Timothy M.

Article 2

Octave-spanning mid-infrared pulses by plasma generation in air pumped with an Yb:KGW source

Optics Letters, v. 41, (21), November 2016, p. 4855-4858
Huang, Jinqing; Alexander Parobek; Ziad Ganim

Substituent Effects on the Photodeprotection Reactions of Selected Ketoprofen Derivatives in Phosphate Buffered Aqueous Solutions

Scientific Reports, v. 6, February 2016, article number 21606
Liu, Mingyue; Li, Mingde; Huang, Jinqing; Li, Tianlu; Liu, Han; Li, Xuechen; Phillips, David Lee

Article 2

How Does the C–Halogen Bond Break in the Photosubstitution Reaction of 3-Fluorobenzophenone in Acidic Aqueous Solutions?

Journal of Organic Chemistry, v. 80, (19), October 2015, p. 9425-9436
Huang, Jinqing; Ma, Jiani; Li, Mingde; Liu, Mingyue; Zhang, Xiting; Phillips, David Lee

Investigation of the Role of Protonation of Benzophenone and Its Derivatives in Acidic Aqueous Solutions Using Time-Resolved Resonance Raman Spectroscopy: How Are Ketyl Radicals Formed in Aqueous Solutions?

Journal of Physical Chemistry B, v. 119, (6), February 2015, p. 2241-2252
Li, Mingde; Huang, Jinqing; Liu, Mingyue; Li, Songbo; Ma, Jiani; Phillips, David Lee

Article 2

A Computational Chemistry Investigation of the Mechanism of the Water-Assisted Decomposition of Trichloroethylene Oxide

Journal of Physical Chemistry A, v. 118, (9), March 2014, p. 1557-1567
Huang, Jinqing; Yeung, Chishun; Ma, Jiani; Gayner, Emma R.; Phillips, David Lee

Direct Time-Resolved Spectroscopic Observation of Arylnitrenium Ion Reactions with Guanine-Containing DNA Oligomers

Journal of Organic Chemistry, v. 79, (8), April 2014, p. 3610-3614
Xue, Jiadan; Du, Lili; Zhu, Ruixue; Huang, Jinqing; Phillips, David Lee

Article 1

Meta Versus Para Substitution: How Does C–H Activation in a Methyl Group Occur in 3-Methylbenzophenone but Does Not Take Place in 4-Methylbenzophenone?

Journal of Organic Chemistry, v. 78, (10), May 2013, p. 4867-4878
Ma, Jiani; Su, Tao; Li, Mingde; Zhang, Xiting; Huang, Jinqing; Phillips, David Lee

Article 1

How and When Does an Unusual and Efficient Photoredox Reaction of 2-(1-Hydroxyethyl) 9,10-Anthraquinone Occur? A Combined Time-Resolved Spectroscopic and DFT Study

Journal of the American Chemical Society, v. 134, (36), September 2012, p. 14858-14868
Ma, Jiani; Su, Tao; Li, Mingde; Du, Wei; Huang, Jinqing; Guan, Xiangguo; Phillips, David Lee

Article 1

Synthesis and luminescence of Eu²⁺-doped alkaline-earth apatites for application in white LED

Journal of Luminescence, v. 130, (4), April 2010, p. 554-559
Zhang, Xinguo; Zhang, Jilin; Huang, Jinqing; Tang, Xueping; Gong, Menglian

Article 1

Near UV-based LED fabricated with Ba₅SiO₄(F,Cl)₆:Eu²⁺ as blue- and green-emitting phosphor

Optical Materials, v. 32, (1), November 2009, p. 75-78
Zhang, Xinguo; Wang, Xiaoxiao; Huang, Jinqing; Shi, Jinxin; Gong, Menglian

2017 1

A spectroscopic study of the excited state proton transfer processes of (8-bromo-7-hydroxyquinolin-2-yl)methyl-protected phenol in aqueous solutions

Photochemical and Photobiological Sciences, v. 16, (4), April 2017, p. 575-584
Huang, Jinqing; Muliawan, Adna P.; Ma, Jiani; Li, Mingde; Chiu, Hoikei; Lan, Xin; Deodato, Davide; Phillips, David Lee; Dore, Timothy M.
Article

2016 2

Octave-spanning mid-infrared pulses by plasma generation in air pumped with an Yb:KGW source

Optics Letters, v. 41, (21), November 2016, p. 4855-4858
Huang, Jinqing; Alexander Parobek; Ziad Ganim
Article

Substituent Effects on the Photodeprotection Reactions of Selected Ketoprofen Derivatives in Phosphate Buffered Aqueous Solutions

Scientific Reports, v. 6, February 2016, article number 21606
Liu, Mingyue; Li, Mingde; Huang, Jinqing; Li, Tianlu; Liu, Han; Li, Xuechen; Phillips, David Lee
Article

2015 2

How Does the C–Halogen Bond Break in the Photosubstitution Reaction of 3-Fluorobenzophenone in Acidic Aqueous Solutions?

Journal of Organic Chemistry, v. 80, (19), October 2015, p. 9425-9436
Huang, Jinqing; Ma, Jiani; Li, Mingde; Liu, Mingyue; Zhang, Xiting; Phillips, David Lee
Article

Investigation of the Role of Protonation of Benzophenone and Its Derivatives in Acidic Aqueous Solutions Using Time-Resolved Resonance Raman Spectroscopy: How Are Ketyl Radicals Formed in Aqueous Solutions?

Journal of Physical Chemistry B, v. 119, (6), February 2015, p. 2241-2252
Li, Mingde; Huang, Jinqing; Liu, Mingyue; Li, Songbo; Ma, Jiani; Phillips, David Lee
Article

2014 2

A Computational Chemistry Investigation of the Mechanism of the Water-Assisted Decomposition of Trichloroethylene Oxide

Journal of Physical Chemistry A, v. 118, (9), March 2014, p. 1557-1567
Huang, Jinqing; Yeung, Chishun; Ma, Jiani; Gayner, Emma R.; Phillips, David Lee
Article

Direct Time-Resolved Spectroscopic Observation of Arylnitrenium Ion Reactions with Guanine-Containing DNA Oligomers

Journal of Organic Chemistry, v. 79, (8), April 2014, p. 3610-3614
Xue, Jiadan; Du, Lili; Zhu, Ruixue; Huang, Jinqing; Phillips, David Lee
Article

2013 1

Meta Versus Para Substitution: How Does C–H Activation in a Methyl Group Occur in 3-Methylbenzophenone but Does Not Take Place in 4-Methylbenzophenone?

Journal of Organic Chemistry, v. 78, (10), May 2013, p. 4867-4878
Ma, Jiani; Su, Tao; Li, Mingde; Zhang, Xiting; Huang, Jinqing; Phillips, David Lee
Article

2012 1

How and When Does an Unusual and Efficient Photoredox Reaction of 2-(1-Hydroxyethyl) 9,10-Anthraquinone Occur? A Combined Time-Resolved Spectroscopic and DFT Study

Journal of the American Chemical Society, v. 134, (36), September 2012, p. 14858-14868
Ma, Jiani; Su, Tao; Li, Mingde; Du, Wei; Huang, Jinqing; Guan, Xiangguo; Phillips, David Lee
Article

2010 1

Synthesis and luminescence of Eu²⁺-doped alkaline-earth apatites for application in white LED

Journal of Luminescence, v. 130, (4), April 2010, p. 554-559
Zhang, Xinguo; Zhang, Jilin; Huang, Jinqing; Tang, Xueping; Gong, Menglian
Article

2009 1

Near UV-based LED fabricated with Ba₅SiO₄(F,Cl)₆:Eu²⁺ as blue- and green-emitting phosphor

Optical Materials, v. 32, (1), November 2009, p. 75-78
Zhang, Xinguo; Wang, Xiaoxiao; Huang, Jinqing; Shi, Jinxin; Gong, Menglian
Article

No Publications

Teaching Assignment

2024-25 Spring 4 2024-25 Winter 0 2024-25 Fall 5 2023-24 Summer 1 2023-24 Spring 1 2023-24 Winter 0

CHEM4689	Capstone Project
SCIE3110	Teaching Science Using Innovative Teaching Tools
UROP1100O	Undergraduate Research Opportunities Series 1
UROP2100O	Undergraduate Research Opportunities Series 2

CHEM4410	Physical Chemistry in Biological Applications
CHEM4689	Capstone Project
CHEM4691	Capstone Research I
SCIE3900	International Research Experience
UROP1100N	Undergraduate Research Opportunities Series 1

UROP1000

Undergraduate Research Opportunities

CHEM3420

Physical Chemistry II

No Teaching Assignments

Research Postgraduate (RPG) Supervision

From January 2022 to December 2025 (As of 15 May 2025)

All Supervisions Current RPGs Graduated RPGs

Current RPGs

Doctor of Philosophy

CHEN, Shijie
Chemistry
ZHANG, Jianing
Chemistry
LIU, Shijia
Chemistry

Graduated RPGs

Doctor of Philosophy

FU, Wenhao
Chemistry( Completed in 2023 )
MESIAS, Vince St. Dollente
Chemistry( Completed in 2023 )

Master of Philosophy

CHIU, King Wai
Chemistry( Completed in 2023 )

Projects

From January 2023 to December 2025

All Projects 6 Leading Projects 5 Participating Projects 1

Unveiling the dynamic interactions of α-synuclein, its mRNA, antisense oligonucleotides, and small molecules by single-molecule force-coupled Raman spectroscopy

透過單分子力譜結合拉曼光譜的方法揭示α-突觸核蛋白、其mRNA、反義寡核苷酸和小分子的動態相互作用 Leading

RGC - General Research Fund
Project Team (HKUST)
HUANG Jinqing (Lead)
2025 -
Single-molecule force-coupled Raman characterizations of the interactions between metal complexes and DNA with specific sequences and structures at single-base resolution

利用單分子力譜結合拉曼光譜的方法以單鹼基分辨率進行金屬配合物與具有特定序列和結構的 DNA 之間的相互作用的表徵研究 Leading

RGC - General Research Fund
Project Team (HKUST)
HUANG Jinqing (Lead)
2024 -
Investigating the interactions between α-synuclein and SARS-CoV-2 proteins and their influences on α-synuclein aggregation by novel single-molecule manipulation and characterization approaches

通過新穎的單分子操控和表徵方法來研究α-突觸核蛋白和 SARS-CoV-2病毒蛋白之間的相互作用及其對α-突觸核蛋白聚集的影響 Leading

RGC - General Research Fund
Project Team (HKUST)
HUANG Jinqing (Lead)
2023 -
The Molecular Mechanism and Function of RNA Helicase DDX21 in Regulating the Virus-induced Immune Response

RNA解旋酶DDX21調控病毒感染引起免疫應答的分子機制和作用機理 Leading

National Natural Science Foundation of China (NSFC) / Research Grants Council (RGC)
Project Team (HKUST)
HUANG Jinqing (Lead)
2022 -
Characterization of alpha-synuclein oligomers and their interaction with membranes under complex physiological factors using optical tweezers-controlled surface-enhanced Raman spectroscopy

用光鑷控制的表面增強拉曼光譜表徵α-突觸核蛋白低聚體及其在複雜生理因素下與膜的相互作用 Leading

RGC - General Research Fund
Project Team (HKUST)
HUANG Jinqing (Lead)
2022 - 2024
Mimicking membraneless organelles by dynamic assembly of polymer-peptide hybrids and nucleic acids

基於聚合物-多肽雜化物及核酸動態組裝的無膜細胞器模擬 Participating

RGC - General Research Fund
Project Team (HKUST)
CHAU Ying (Lead)

HUANG Jinqing
2021 - 2023

Research Interest

Publications

2024 18

2023 7

2022 14

2021 5

2020 5

2017 1

2016 2

2015 2

2014 2

2013 1

2012 1

2010 1

2009 1

Article 12

Conference paper 6

Article 6

Conference paper 1

Article 11

Conference paper 3

Article 3

Conference paper 2

Article 3

Conference paper 2

Article 1

Article 2

Article 2

Article 2

Article 1

Article 1

Article 1

Article 1

2017 1

2016 2

2015 2

2014 2

2013 1

2012 1

2010 1

2009 1

Teaching Assignment

Research Postgraduate (RPG) Supervision

From January 2022 to December 2025 (As of 15 May 2025)

Current RPGs

Graduated RPGs

Projects

From January 2023 to December 2025

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