Faculty Profiles - GAO Jieqiong | The Hong Kong University of Science and Technology

Jieqiong GAO
高潔瓊

Doctor of Natural Sciences
University of Osnabrück, 2018

Assistant Professor
Division of Life Science

(852) 2358 7293
jqgao@ust.hk
Room 5544
Personal Web

Google Scholar

2VrB1-AAAAAJ

ORCID

0000-0002-5223-6547

ResearcherID

EUZ-5948-2022

Scopus ID

57193083800

Research Interest Publications

Research Interest

Cellular and molecular mechanisms
Cell biology
Cell signaling
Intracellular protein trafficking
Membrane trafficking

Publications

All Years 16 2025 0 2024 0 2023 1 2022 1 2021 1 2020 1 2019 12

2023 1

Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuole

Journal of Cell Science, v. 136, (12), June 2023, article number jcs260889
Grziwa, Sophie; Schäfer, Jan-Hannes; Nicastro, Raffaele; Arens, Annabel; De Virgilio, Claudio; Fröhlich, Florian; Moeller, Arne; Gao, Jieqiong; Langemeyer, Lars; Ungermann, Christian
Article

2022 1

The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity

Journal of Cell Biology, v. 221, (5), May 2022, article number e202109084
Gao, Jieqiong; Nicastro, Raffaele; Péli-Gulli, Marie-Pierre; Grziwa, Sophie; Chen, Zilei; Kurre, Rainer; Piehler, Jacob; De Virgilio, Claudio; Fröhlich, Florian; Ungermann, Christian
Article

2021 1

TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles

Current Biology, v. 31, (2), January 2021, p. 297-309.e8
Chen, Zilei; Malia, Pedro Carpio; Hatakeyama, Riko; Nicastro, Raffaele; Hu, Zehan; Péli-Gulli, Marie-Pierre; Gao, Jieqiong; Nishimura, Taki; Eskes, Elja; Stefan, Christopher J.; Winderickx, Joris; Dengjel, Jörn; De Virgilio, Claudio; Ungermann, Christian
Article

2020 1

Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex

EMBO Reports, v. 21, (12), December 2020, article number e50733
Gao, Jieqiong; Kurre, Rainer; Rose, Jaqueline; Walter, Stefan; Fröhlich, Florian; Piehler, Jacob; Reggiori, Fulvio; Ungermann, Christian
Article

2019 1

The multi-functional SNARE protein Ykt6 in autophagosomal fusion processes

Cell Cycle, v. 18, (6-7), April 2019, p. 639-651
Kriegenburg, Franziska; Bas, Levent; Gao, Jieqiong; Ungermann, Christian; Kraft, Claudine
Article

2018 2

A novel in vitro assay reveals SNARE topology and the role of Ykt6 in autophagosome fusion with vacuoles

Journal of Cell Biology, v. 217, (10), October 2018, p. 3670-3682
Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian
Article

Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure

eLife, v. 7, February 2018, article number e31145
Gao, Jieqiong; Langemeyer, Lars; Kümmel, Daniel; Reggiori, Fulvio; Ungermann, Christian
Article

2017 2

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

Nature Communications, v. 8, (1), December 2017, article number 295
Sánchez-Wandelmer, Jana; Kriegenburg, Franziska; Rohringer, Sabrina; Schuschnig, Martina; Gómez-Sánchez, Rubén; Zens, Bettina; Abreu, Susana; Hardenberg, Ralph; Hollenstein, David; Gao, Jieqiong; Ungermann, Christian; Martens, Sascha; Kraft, Claudine; Reggiori, Fulvio
Article

Multivalent Rab interactions determine tether-mediated membrane fusion

Molecular Biology of the Cell, v. 28, (2), January 2017, p. 322-332
Lürick, Anna; Gao, Jieqiong; Kuhlee, Anne; Yavavli, Erdal; Langemeyer, Lars; Perz, Angela; Raunser, Stefan; Ungermann, Christian
Article

2014 4

Dual effects of carnosine on energy metabolism of cultured cortical astrocytes under normal and ischemic conditions

Regulatory Peptides, v. 192, June 2014, p. 45-52
Shen, Yao; Tian, Yueyang; Yang, Jianbo; Shi, Xiaojie; Ouyang, Li; Gao, Jieqiong; Lu, Jianxin
Article

Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy

Autophagy, v. 10, (10), October 2014, p. 1801-1813
Zhang, Xiangnan; Yuan, Yang; Jiang, Lei; Zhang, Jingying; Gao, Jieqiong; Shen, Zhe; Zheng, Yanrong; Deng, Tian; Yan, Haijing; Li, Wenlu; Hou, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Zhang, Zhuohua; Chen, Zhong
Article

Exposure to high glutamate concentration activates aerobic glycolysis but inhibits ATP-linked respiration in cultured cortical astrocytes

Cell Biochemistry and Function, v. 32, (6), July 2014, article number 10.1002/cbf.3047, p. 530-537
Shen, Yao; Tian, Yueyang; Shi, Xiaojie; Yang, Jianbo; Ouyang, Li; Gao, Jieqiong; Lu, Jianxin
Article

Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms

Nature Communications, v. 5, February 2014, article number 3334
Yan, Haijing; Zhang, Xiangnan; Ma, Jing; Hou, Weiwei; Zhang, Xingzhou; Wang, Xiaofen; Gao, Jieqiong; Shen, Yao; Lv, Jianxin; Ohtsu, Hiroshi; Han, Feng; Wang, Guanghui; Chen, Zhong
Article

2013 2

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

Autophagy, v. 9, (9), September 2013, p. 1321-1333
Zhang, Xiangnan; Yan, Haijing; Yuan, Yang; Gao, Jieqiong; Shen, Zhe; Cheng, Yun; Shen, Yao; Wang, Rong-Rong; Wang, Xiaofen; Hu, Wei-Wei; Wang, Guanghui; Chen, Zhong
Article

Modulation of astrocytic glutamine synthetase expression and cell viability by histamine in cultured cortical astrocytes exposed to OGD insults

Neuroscience Letters, v. 549, August 2013, p. 69-73
Wang, Xiao-fen; Hu, Wei-wei; Yan, Hai-jing; Tan, Li; Gao, Jie-qiong; Tian, Yue-yang; Shi, Xiao-jie; Hou, Wei-wei; Li, Juan; Shen, Yao; Chen, Zhong
Article

2012 1

Acidic preconditioning protects against ischemia-induced brain injury

Neuroscience Letters, v. 523, (1), August 2012, p. 3-8
Zhang, Chen-hui; Fan, Yan-ying; Wang, Xiao-fen; Xiong, Jia-yan; Tang, Ying-ying; Gao, Jie-qiong; Shen, Zhe; Song, Xiao-hui; Zhang, Jing-ying; Shen, Yao; Li, Qing; Zhang, Xiangnan; Chen, Zhong
Article

Article 1

Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuole

Journal of Cell Science, v. 136, (12), June 2023, article number jcs260889
Grziwa, Sophie; Schäfer, Jan-Hannes; Nicastro, Raffaele; Arens, Annabel; De Virgilio, Claudio; Fröhlich, Florian; Moeller, Arne; Gao, Jieqiong; Langemeyer, Lars; Ungermann, Christian

Article 1

The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity

Journal of Cell Biology, v. 221, (5), May 2022, article number e202109084
Gao, Jieqiong; Nicastro, Raffaele; Péli-Gulli, Marie-Pierre; Grziwa, Sophie; Chen, Zilei; Kurre, Rainer; Piehler, Jacob; De Virgilio, Claudio; Fröhlich, Florian; Ungermann, Christian

Article 1

TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles

Current Biology, v. 31, (2), January 2021, p. 297-309.e8
Chen, Zilei; Malia, Pedro Carpio; Hatakeyama, Riko; Nicastro, Raffaele; Hu, Zehan; Péli-Gulli, Marie-Pierre; Gao, Jieqiong; Nishimura, Taki; Eskes, Elja; Stefan, Christopher J.; Winderickx, Joris; Dengjel, Jörn; De Virgilio, Claudio; Ungermann, Christian

Article 1

Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex

EMBO Reports, v. 21, (12), December 2020, article number e50733
Gao, Jieqiong; Kurre, Rainer; Rose, Jaqueline; Walter, Stefan; Fröhlich, Florian; Piehler, Jacob; Reggiori, Fulvio; Ungermann, Christian

Article 1

The multi-functional SNARE protein Ykt6 in autophagosomal fusion processes

Cell Cycle, v. 18, (6-7), April 2019, p. 639-651
Kriegenburg, Franziska; Bas, Levent; Gao, Jieqiong; Ungermann, Christian; Kraft, Claudine

Article 2

A novel in vitro assay reveals SNARE topology and the role of Ykt6 in autophagosome fusion with vacuoles

Journal of Cell Biology, v. 217, (10), October 2018, p. 3670-3682
Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian

Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure

eLife, v. 7, February 2018, article number e31145
Gao, Jieqiong; Langemeyer, Lars; Kümmel, Daniel; Reggiori, Fulvio; Ungermann, Christian

Article 2

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

Nature Communications, v. 8, (1), December 2017, article number 295
Sánchez-Wandelmer, Jana; Kriegenburg, Franziska; Rohringer, Sabrina; Schuschnig, Martina; Gómez-Sánchez, Rubén; Zens, Bettina; Abreu, Susana; Hardenberg, Ralph; Hollenstein, David; Gao, Jieqiong; Ungermann, Christian; Martens, Sascha; Kraft, Claudine; Reggiori, Fulvio

Multivalent Rab interactions determine tether-mediated membrane fusion

Molecular Biology of the Cell, v. 28, (2), January 2017, p. 322-332
Lürick, Anna; Gao, Jieqiong; Kuhlee, Anne; Yavavli, Erdal; Langemeyer, Lars; Perz, Angela; Raunser, Stefan; Ungermann, Christian

Article 4

Dual effects of carnosine on energy metabolism of cultured cortical astrocytes under normal and ischemic conditions

Regulatory Peptides, v. 192, June 2014, p. 45-52
Shen, Yao; Tian, Yueyang; Yang, Jianbo; Shi, Xiaojie; Ouyang, Li; Gao, Jieqiong; Lu, Jianxin

Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy

Autophagy, v. 10, (10), October 2014, p. 1801-1813
Zhang, Xiangnan; Yuan, Yang; Jiang, Lei; Zhang, Jingying; Gao, Jieqiong; Shen, Zhe; Zheng, Yanrong; Deng, Tian; Yan, Haijing; Li, Wenlu; Hou, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Zhang, Zhuohua; Chen, Zhong

Exposure to high glutamate concentration activates aerobic glycolysis but inhibits ATP-linked respiration in cultured cortical astrocytes

Cell Biochemistry and Function, v. 32, (6), July 2014, article number 10.1002/cbf.3047, p. 530-537
Shen, Yao; Tian, Yueyang; Shi, Xiaojie; Yang, Jianbo; Ouyang, Li; Gao, Jieqiong; Lu, Jianxin

Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms

Nature Communications, v. 5, February 2014, article number 3334
Yan, Haijing; Zhang, Xiangnan; Ma, Jing; Hou, Weiwei; Zhang, Xingzhou; Wang, Xiaofen; Gao, Jieqiong; Shen, Yao; Lv, Jianxin; Ohtsu, Hiroshi; Han, Feng; Wang, Guanghui; Chen, Zhong

Article 2

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

Autophagy, v. 9, (9), September 2013, p. 1321-1333
Zhang, Xiangnan; Yan, Haijing; Yuan, Yang; Gao, Jieqiong; Shen, Zhe; Cheng, Yun; Shen, Yao; Wang, Rong-Rong; Wang, Xiaofen; Hu, Wei-Wei; Wang, Guanghui; Chen, Zhong

Modulation of astrocytic glutamine synthetase expression and cell viability by histamine in cultured cortical astrocytes exposed to OGD insults

Neuroscience Letters, v. 549, August 2013, p. 69-73
Wang, Xiao-fen; Hu, Wei-wei; Yan, Hai-jing; Tan, Li; Gao, Jie-qiong; Tian, Yue-yang; Shi, Xiao-jie; Hou, Wei-wei; Li, Juan; Shen, Yao; Chen, Zhong

Article 1

Acidic preconditioning protects against ischemia-induced brain injury

Neuroscience Letters, v. 523, (1), August 2012, p. 3-8
Zhang, Chen-hui; Fan, Yan-ying; Wang, Xiao-fen; Xiong, Jia-yan; Tang, Ying-ying; Gao, Jie-qiong; Shen, Zhe; Song, Xiao-hui; Zhang, Jing-ying; Shen, Yao; Li, Qing; Zhang, Xiangnan; Chen, Zhong

2019 1

The multi-functional SNARE protein Ykt6 in autophagosomal fusion processes

Cell Cycle, v. 18, (6-7), April 2019, p. 639-651
Kriegenburg, Franziska; Bas, Levent; Gao, Jieqiong; Ungermann, Christian; Kraft, Claudine
Article

2018 2

A novel in vitro assay reveals SNARE topology and the role of Ykt6 in autophagosome fusion with vacuoles

Journal of Cell Biology, v. 217, (10), October 2018, p. 3670-3682
Gao, Jieqiong; Reggiori, Fulvio; Ungermann, Christian
Article

Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure

eLife, v. 7, February 2018, article number e31145
Gao, Jieqiong; Langemeyer, Lars; Kümmel, Daniel; Reggiori, Fulvio; Ungermann, Christian
Article

2017 2

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

Nature Communications, v. 8, (1), December 2017, article number 295
Sánchez-Wandelmer, Jana; Kriegenburg, Franziska; Rohringer, Sabrina; Schuschnig, Martina; Gómez-Sánchez, Rubén; Zens, Bettina; Abreu, Susana; Hardenberg, Ralph; Hollenstein, David; Gao, Jieqiong; Ungermann, Christian; Martens, Sascha; Kraft, Claudine; Reggiori, Fulvio
Article

Multivalent Rab interactions determine tether-mediated membrane fusion

Molecular Biology of the Cell, v. 28, (2), January 2017, p. 322-332
Lürick, Anna; Gao, Jieqiong; Kuhlee, Anne; Yavavli, Erdal; Langemeyer, Lars; Perz, Angela; Raunser, Stefan; Ungermann, Christian
Article

2014 4

Dual effects of carnosine on energy metabolism of cultured cortical astrocytes under normal and ischemic conditions

Regulatory Peptides, v. 192, June 2014, p. 45-52
Shen, Yao; Tian, Yueyang; Yang, Jianbo; Shi, Xiaojie; Ouyang, Li; Gao, Jieqiong; Lu, Jianxin
Article

Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy

Autophagy, v. 10, (10), October 2014, p. 1801-1813
Zhang, Xiangnan; Yuan, Yang; Jiang, Lei; Zhang, Jingying; Gao, Jieqiong; Shen, Zhe; Zheng, Yanrong; Deng, Tian; Yan, Haijing; Li, Wenlu; Hou, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Lu, Jianxin; Shen, Yao; Dai, Haibing; Hu, Wei-Wei; Zhang, Zhuohua; Chen, Zhong
Article

Exposure to high glutamate concentration activates aerobic glycolysis but inhibits ATP-linked respiration in cultured cortical astrocytes

Cell Biochemistry and Function, v. 32, (6), July 2014, article number 10.1002/cbf.3047, p. 530-537
Shen, Yao; Tian, Yueyang; Shi, Xiaojie; Yang, Jianbo; Ouyang, Li; Gao, Jieqiong; Lu, Jianxin
Article

Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms

Nature Communications, v. 5, February 2014, article number 3334
Yan, Haijing; Zhang, Xiangnan; Ma, Jing; Hou, Weiwei; Zhang, Xingzhou; Wang, Xiaofen; Gao, Jieqiong; Shen, Yao; Lv, Jianxin; Ohtsu, Hiroshi; Han, Feng; Wang, Guanghui; Chen, Zhong
Article

2013 2

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

Autophagy, v. 9, (9), September 2013, p. 1321-1333
Zhang, Xiangnan; Yan, Haijing; Yuan, Yang; Gao, Jieqiong; Shen, Zhe; Cheng, Yun; Shen, Yao; Wang, Rong-Rong; Wang, Xiaofen; Hu, Wei-Wei; Wang, Guanghui; Chen, Zhong
Article

Modulation of astrocytic glutamine synthetase expression and cell viability by histamine in cultured cortical astrocytes exposed to OGD insults

Neuroscience Letters, v. 549, August 2013, p. 69-73
Wang, Xiao-fen; Hu, Wei-wei; Yan, Hai-jing; Tan, Li; Gao, Jie-qiong; Tian, Yue-yang; Shi, Xiao-jie; Hou, Wei-wei; Li, Juan; Shen, Yao; Chen, Zhong
Article

2012 1

Acidic preconditioning protects against ischemia-induced brain injury

Neuroscience Letters, v. 523, (1), August 2012, p. 3-8
Zhang, Chen-hui; Fan, Yan-ying; Wang, Xiao-fen; Xiong, Jia-yan; Tang, Ying-ying; Gao, Jie-qiong; Shen, Zhe; Song, Xiao-hui; Zhang, Jing-ying; Shen, Yao; Li, Qing; Zhang, Xiangnan; Chen, Zhong
Article

No Publications

Research Interest

Publications

2023 1

2022 1

2021 1

2020 1

2019 1

2018 2

2017 2

2014 4

2013 2

2012 1

Article 1

Article 1

Article 1

Article 1

Article 1

Article 2

Article 2

Article 4

Article 2

Article 1

2019 1

2018 2

2017 2

2014 4

2013 2

2012 1

Projects

From January 2023 to December 2025

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