Crystal structure of a tetrameric RNA G-quadruplex formed by hexanucleotide repeat expansions of C9orf72 in ALS/FTD

Discovery of a novel marine bacterial AIEgen that lights up specific G-quadruplexes

PRDX1 Interfering Peptide Disrupts Amino Acids 70–90 of PRDX1 to Inhibit the TLR4/NF-κB Signaling Pathway and Attenuate Neuroinflammation and Ischemic Brain Injury

TAT-W61 peptide attenuates neuronal injury through blocking the binding of S100b to the V-domain of Rage during ischemic stroke

The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex

An Essential Noc3p Dimerization Cycle Mediates ORC Double-Hexamer Formation in Replication Licensing

Capturing the hierarchically assorted modules of protein-protein interactions in the organized nucleome

Inhibition of human oral squamous cell carcinoma proliferation and migration by prodrug-activating suicide gene therapies

Cryo-EM structure of human hexameric MCM2-7 complex

Selective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models

The parallel tetrameric DNA G-quadruplex formed by the two-repeat C9orf72 GGGGCC sequence in solution: Dedicated to Professor Chaohui Ye on the occasion of his 80th birthday

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS-and FTD-related GGGGCC sequence

Isotopically Dimethyl Labeling-Based Quantitative Proteomic Analysis Of Phosphoproteomes Of Soybean Cultivars

Quantitative evaluation and comparison of two prodrug-activating suicide gene therapies on oral squamous cell carcinoma

Simultaneous Real-Time Three-Dimensional Localization and FRET Measurement of Two Distinct Particles

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS and FTD related GGGGCC sequence

An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication

Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution

G-quadruplex structures formed by human telomeric DNA and C9orf72 hexanucleotide repeats

The Biophysical Society of Hong Kong (BPHK): past, present, and future

The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites

Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence

Responsive Upconversion Nanoprobe for Monitoring and Inhibition of EBV-Associated Cancers via Targeting EBNA1

G-quadruplex Structures Formed by Human Telomeric DNA and C9orf72 Hexanucleotide Repeats

Mechanistic study of human DNA replication proteins that regulate cell proliferation and differentiation

Structure-functional Study of G-rich Oligonucleotides

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Mediated Latent DNA replication in Human Cells

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1(EBNA1) Mediated DNA Replication in Human Cells

与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction

Quadruplex Nucleic Acid Structure Determination by Solution NMR

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Mechanistic Study of Human DNA Replication Initiation and Relating Diseases

Mechanistic study of human proteins that regulate cell proliferation and differentiation

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation

Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation

Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad

Structure-functional study of human pre-replication complex

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex

Dynamic Nuclear Polarization: New Methodology and Applications

NMR of Proteins and Small Biomolecules Preface

Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode

Structural basis for homeodomain recognition by the cell-cycle regulator Geminin

Structural insights into the Cdt1-mediated MCM2-7 chromatin loading

Crowding effect on calmodulin bakcbone dynamics

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)

1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNALeu (CAG)

NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry

Recent development in DMP(chapter 8), Advance Topics in Chemistry

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6

Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk

Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy

The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells

Characterization and structural determination of the Cdt1 binding domain of human Mcm6

Solution structure of the Cdt1 binding domain of human Mcm6

The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome

Identification of the functional domains involved in the interaction between human Cdt1 and Mcm6

MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9

SET8 plays a role in controlling G(1)/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail

TROSY-based NMR experiments for NMR studies of large biomolecules

Interaction between trichosanthin, a ribosome inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation

SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20

(3,2)D GFT-NMR experiments for fast data collection from proteins

Elucidation of the solution conformations of loloatin C by NMR Spectroscopy and molecular simulation

Escherichia coli tRNA₄^Arg(UCU) induces a constrained conformation of the crucial Ω-loop of arginyl-tRNA synthetase

Protein flexibility and intrinsic disorder

TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins.

TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding.

TROSY based correlation and NOE spectroscopy for NMR structural studies of large proteins

TROSY-Based NMR Experiments for the Study of Macromolecular Dynamics and Hydrogen Bonding

Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity

Improved amino acid flexibility parameters

Interaction between calcium-free calmodulin and IQ motif of neurogranin studied by nuclear magnetic resonance spectroscopy

Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex

Substrate-induced conformational changes in Escherichia coli arginyl-tRNA synthetase observed by F-19 NMR spectroscopy

Clean SEA-HSQC: A method to map solvent exposed amides in large non-deuterated proteins with gradient-enhanced HSQC

Investigation of the structural stability of the human acidic fibroblast growth factor by hydrogen-deuterium exchange

Letter to the Editor: Complete ¹H, ¹⁵N and ¹³C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR)

Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro

NMR Analysis of Bovine tRNA(Trp) - Conformation Dependence of Mg2+ Binding

Protein dynamics measurements by 3D HNCO based NMR experiments

Recognition by Tryptophanyl-tRNA Synthetases of Discriminator Bbase on tRNA(TrP) from Three Biological Domains

Multidimensional NMR data processing

NMR analysis of bovine tRNATrp: conformational dependence of Mg2+ binding sites

3D H-aro-NOESY-CH3NH and C-aro-NOESY-CH3NH experiments for double labeled proteins

The dual effects of ethylene on the negative gravicurvature of arabidopsis inflorescence, an intriguing action model for the plant hormone ethylene

Multidimensional NMR Spectroscopic Signal Processing

A J-multiplied HMQC (MJ-HMQC) experiment for measuring ³J_HNHα coupling constants

Cernuosides A and B, two sucrase inhibitors from Pulsatilla cernua

Determination of internucleotide (h)J(HN) couplings by the modified 2D J(NN)-correlated [N-15, H-1] TROSY

NMR studies of Bacillus subtilis tRNA(Trp) hyperexpressed in Escherichia coli - Assignment of imino proton signals and determination of thermal stability

Protein dynamics measurements by TROSY-based NMR experiments

Sensitivity enhancement of HCACO by using an HMQC magnetization transfer scheme

Transverse relaxation optimized 3D and 4D N-15/N-15 separated NOESY experiments of N-15 labeled proteins

2D and 3D TROSY-enhanced NOESY of N-15 labeled proteins

Gradient and sensitivity enhanced multiple-quantum coherence in heteronuclear multidimensional NMR experiments

Gradient and sensitivity enhancement of 2D TROSY with water flip-back, 3D NOESY-TROSY and TOCSY-TROSY experiments

Phase sensitive 3D J-resolved HMBC experiment for spectral assignment and measurement of long-range heteronuclear coupling constants

Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy

Sensitivity enhancement in transverse relaxation optimized NMR spectroscopy

Spectral parameter estimation by an iterative quadratic maximum likelihood method

Suppression of diagonal peaks with singular value decomposition

Post-acquisition solvent suppression by singular-value decomposition

Quantitative NMR signal analysis by an iterative quadratic maximum likelihood method

Using neural network predicted secondary structure information in automatic protein NMR assignment

Application of a three-dimensional maximum-entropy method to processing sections of three-dimensional NMR spectra

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

Analysis of Sugar Puckers and Glycosidic Torsion Angles in a DNA G-Tetrad Structure by Heteronuclear Three-Bond J Couplings

Measurement of two- and three-bond 1H-13C J couplings from quantitative heteronuclear J correlation for molecules with overlapping 1H resonances, Using T1 Noise Reduction

Stable Isotope Applications in Biomolecular Structure and Mechanisms

Measurement of homo- and heteronuclear J couplings from quantitative J correlation

Discrete Fourier Transformation of NMR Signals. The Relationship between Sampling Delay Time and Spectral Baseline

Quantitative Measurement of Long-range 1H-13C J Couplings from Proton Detected HMBC Spectra.

Improved Linear Prediction of Truncated Damped Sinusoids Using modified Backward-Forward Linear Prediction

Solution Structure of a Calmodulin-Target Peptide Complex by Multidimensional NMR

Four-Dimensional Heteronuclear Triple Resonance NMR of Isotopically Enriched Proteins for Sequential assignment of Backbone atoms.

Removal of F1 Baseline Distortion and Optimization of Folding in Multi-Dimensional NMR Spectra

Two-dimensional Linear Prediction for Signals Truncated in Both Dimensions

Improved Linear Prediction for Truncated Signals of Known Phase.

Distribution of Energy in Polymers Due to Incident Electrons and Protons

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites

Article

Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence

Article

Responsive Upconversion Nanoprobe for Monitoring and Inhibition of EBV-Associated Cancers via Targeting EBNA1

Article

G-quadruplex Structures Formed by Human Telomeric DNA and C9orf72 Hexanucleotide Repeats

Conference paper

Mechanistic study of human DNA replication proteins that regulate cell proliferation and differentiation

Conference paper

Structure-functional Study of G-rich Oligonucleotides

Conference paper

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Conference paper

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) Mediated Latent DNA replication in Human Cells

Conference paper

Mechanistic Study of Epstein-Barr Virus Nuclear Antigen 1(EBNA1) Mediated DNA Replication in Human Cells

Conference paper

与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构

Conference paper

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction

Article

Quadruplex Nucleic Acid Structure Determination by Solution NMR

Article

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Article

Mechanistic Study of Human DNA Replication Initiation and Relating Diseases

Conference paper

Mechanistic study of human proteins that regulate cell proliferation and differentiation

Conference paper

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad

Conference paper

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad

Article

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad

Conference paper

Structure-functional study of human pre-replication complex

Conference paper

Mechanistic Study of Human Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex

Conference paper

Dynamic Nuclear Polarization: New Methodology and Applications

Article

NMR of Proteins and Small Biomolecules Preface

Article

Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode

Article

Structural basis for homeodomain recognition by the cell-cycle regulator Geminin

Article

Structural insights into the Cdt1-mediated MCM2-7 chromatin loading

Article

Crowding effect on calmodulin bakcbone dynamics

Conference paper

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)

Article

1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNALeu (CAG)

Article

NMR of Proteins or Small Biomolecules, Advance Topics in Chemistry

Book

Recent development in DMP(chapter 8), Advance Topics in Chemistry

Book chapter

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Conference paper

Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6

Conference paper

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6

Article

Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Article

Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk

Article

Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy

Article

The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells

Article

Characterization and structural determination of the Cdt1 binding domain of human Mcm6

Conference paper

Solution structure of the Cdt1 binding domain of human Mcm6

Conference paper

The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome

Article

Identification of the functional domains involved in the interaction between human Cdt1 and Mcm6

Conference paper

MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9

Article

SET8 plays a role in controlling G(1)/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail

Article

TROSY-based NMR experiments for NMR studies of large biomolecules

Article

Interaction between trichosanthin, a ribosome inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses

Article

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation

Article

SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20

Article

(3,2)D GFT-NMR experiments for fast data collection from proteins

Article

Elucidation of the solution conformations of loloatin C by NMR Spectroscopy and molecular simulation

Article

Escherichia coli tRNA₄^Arg(UCU) induces a constrained conformation of the crucial Ω-loop of arginyl-tRNA synthetase

Article

Protein flexibility and intrinsic disorder

Article

TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins.

Article

TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding.

Article

TROSY based correlation and NOE spectroscopy for NMR structural studies of large proteins

Book chapter

TROSY-Based NMR Experiments for the Study of Macromolecular Dynamics and Hydrogen Bonding

Book chapter

Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity

Article

Improved amino acid flexibility parameters

Article

Interaction between calcium-free calmodulin and IQ motif of neurogranin studied by nuclear magnetic resonance spectroscopy

Article

Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex

Article

Substrate-induced conformational changes in Escherichia coli arginyl-tRNA synthetase observed by F-19 NMR spectroscopy

Article

Clean SEA-HSQC: A method to map solvent exposed amides in large non-deuterated proteins with gradient-enhanced HSQC

Article

Investigation of the structural stability of the human acidic fibroblast growth factor by hydrogen-deuterium exchange

Article

Letter to the Editor: Complete ¹H, ¹⁵N and ¹³C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR)

Article

Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro

Article

NMR Analysis of Bovine tRNA(Trp) - Conformation Dependence of Mg2+ Binding

Article

Protein dynamics measurements by 3D HNCO based NMR experiments

Article

Recognition by Tryptophanyl-tRNA Synthetases of Discriminator Bbase on tRNA(TrP) from Three Biological Domains

Article

Multidimensional NMR data processing

Book chapter

NMR analysis of bovine tRNATrp: conformational dependence of Mg2+ binding sites

Conference paper

3D H-aro-NOESY-CH3NH and C-aro-NOESY-CH3NH experiments for double labeled proteins

Article

The dual effects of ethylene on the negative gravicurvature of arabidopsis inflorescence, an intriguing action model for the plant hormone ethylene

Article

Multidimensional NMR Spectroscopic Signal Processing

Book chapter

A J-multiplied HMQC (MJ-HMQC) experiment for measuring ³J_HNHα coupling constants

Article

Cernuosides A and B, two sucrase inhibitors from Pulsatilla cernua

Article

Determination of internucleotide (h)J(HN) couplings by the modified 2D J(NN)-correlated [N-15, H-1] TROSY

Article

NMR studies of Bacillus subtilis tRNA(Trp) hyperexpressed in Escherichia coli - Assignment of imino proton signals and determination of thermal stability

Article

Protein dynamics measurements by TROSY-based NMR experiments

Article

Sensitivity enhancement of HCACO by using an HMQC magnetization transfer scheme

Article

Transverse relaxation optimized 3D and 4D N-15/N-15 separated NOESY experiments of N-15 labeled proteins

Article

2D and 3D TROSY-enhanced NOESY of N-15 labeled proteins

Article

Gradient and sensitivity enhanced multiple-quantum coherence in heteronuclear multidimensional NMR experiments

Article

Gradient and sensitivity enhancement of 2D TROSY with water flip-back, 3D NOESY-TROSY and TOCSY-TROSY experiments

Article

Phase sensitive 3D J-resolved HMBC experiment for spectral assignment and measurement of long-range heteronuclear coupling constants

Article

Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy

Article

Sensitivity enhancement in transverse relaxation optimized NMR spectroscopy

Article

Spectral parameter estimation by an iterative quadratic maximum likelihood method

Article

Suppression of diagonal peaks with singular value decomposition

Article

Post-acquisition solvent suppression by singular-value decomposition

Article

Quantitative NMR signal analysis by an iterative quadratic maximum likelihood method

Article

Using neural network predicted secondary structure information in automatic protein NMR assignment

Article

Application of a three-dimensional maximum-entropy method to processing sections of three-dimensional NMR spectra

Article

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

Article

Analysis of Sugar Puckers and Glycosidic Torsion Angles in a DNA G-Tetrad Structure by Heteronuclear Three-Bond J Couplings

Article

Measurement of two- and three-bond 1H-13C J couplings from quantitative heteronuclear J correlation for molecules with overlapping 1H resonances, Using T1 Noise Reduction

Article

Stable Isotope Applications in Biomolecular Structure and Mechanisms

Article

Measurement of homo- and heteronuclear J couplings from quantitative J correlation

Book chapter

Discrete Fourier Transformation of NMR Signals. The Relationship between Sampling Delay Time and Spectral Baseline

Article

Quantitative Measurement of Long-range 1H-13C J Couplings from Proton Detected HMBC Spectra.

Article

Improved Linear Prediction of Truncated Damped Sinusoids Using modified Backward-Forward Linear Prediction

Article

Solution Structure of a Calmodulin-Target Peptide Complex by Multidimensional NMR

Article

Four-Dimensional Heteronuclear Triple Resonance NMR of Isotopically Enriched Proteins for Sequential assignment of Backbone atoms.

Article

Removal of F1 Baseline Distortion and Optimization of Folding in Multi-Dimensional NMR Spectra

Article

Two-dimensional Linear Prediction for Signals Truncated in Both Dimensions

Article

Improved Linear Prediction for Truncated Signals of Known Phase.

Article

Distribution of Energy in Polymers Due to Incident Electrons and Protons

Article