Faculty Profiles - FUNG Erik | The Hong Kong University of Science and Technology

Erik FUNG
馮以文

MD(Res) in Epidemiology
Imperial College London, 2022

PhD in Medical Genetics
University of Cambridge, 2010

MBChB in Medicine and Surgery
The Chinese University of Hong Kong, 2004

Clinical Associate Professor
Division of Life Science

(852) 3469 3364
erikfung@ust.hk
Room 5525

Google Scholar

OCVyR-YAAAAJ

ResearcherID

CPQ-2868-2022

Scopus ID

55372353100

Research Interest Publications

Research Interest

Heart failure and frailty
Inflammaging
Cardiomyopathies
Sports cardiology

Publications

All Years 97 2025 8 2024 6 2023 5 2022 7 2021 9 2020 11 2019 51

2025 8

Consolidating Concepts From Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management

Journal of Cardiac Failure, v. 137, (1), June 2025, p. 1-10
Lau, Gloria H.W.; Auyeung, Tung Wai; Joyce, Emer; McDonagh, Julee; Yu, Ka Man; Woo, Jean; Lee, Jenny S.W.; Jha, Sunita; MacDonald, Peter S.; Fung, Erik
Article

Effects of recombinant GDF15 pretreatment on mitochondrial damage and cytotoxicity induced by doxorubicin in human stem cell-derived cardiomyocytes

European Journal of Heart Failure, v. 27, (S1), March 2025, article number 21
Fung, Erik; Luo, H.; Chen, JCH; Poon, E.
Article

eSports, exergames, and eAthletes: opportunities and challenges for preventive cardiology on a global scale

European Journal of Preventive Cardiology, v. 32, (1), January 2025, p. 88-90
Fung, Erik; Pelliccia, Antonio
Article

Modeling of G2151S Missense Mutation in Filamin C Cardiomyopathy Reveals Alteration in Phosphorylation Affecting Binding with FILIP1

The Journal of Heart and Lung Transplantation, v. 44, (4), April 2025, p. S221-S222
Zhang, X.; Guo, D.; Zhao, H.; Yang, D.; Fung, Erik
Article

NT-proBNP improves prediction of cardiorenal complications in type 2 diabetes: the Hong Kong Diabetes Biobank

Diabetologia, v. 68, (2), February 2025, p. 342-356
Ma, Ronald C. W.; Tam, Claudia H. T.; Hou, Yong; Lau, Eric S. H.; Ozaki, Risa; Lui, Juliana N. M.; Chow, Elaine; Kong, Alice P. S.; Huang, Chuiguo; Ng, Alex C. W.; Fung, Erik G.; Luk, Andrea O. Y.; So, Wing Yee; Lim, Cadmon K. P.; Chan, Juliana C. N.
Article

Effects of recombinant GDF15 pretreatment on mitochondrial damage and cytotoxicity induced by doxorubicin in human stem cell-derived cardiomyocytes

European Journal of Heart Failure Supplements, June 2025
Fung, Erik; Luo, H.; Chen, JCH; Poon, E.
Conference paper

Effects of recombinant GDF15 pretreatment on mitochondrial damage and cytotoxicity induced by doxorubicin in human stem cell-derived cardiomyocytes

N/A / European Society of Cardiology (ESC). European Society of Cardiology (ESC), 2025
Fung, Erik
Conference paper

Portable Electrical Impedance Tomography Enables Heart Ejection Fraction Measurement for Health Screening in Nonspecialist Settings

2025 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2025) / Institute of Electrical and Electronics Engineers. Institute of Electrical and Electronics Engineers, 2025
Lawson, Michael; Lui, Henry; Huen, Vicky; Chan, Kannie W.Y.; Chan, Kevin C.; Wong, Eddie C.; Fung, Erik; Chan, Russell W.
Conference paper

2024 6

A Longitudinal 20-year Analysis Indicates Acceleration of Cardiometabolic Comorbidities on Dementia Risk

Circulation, v. 150, (Supplement 1), November 2024
Huang, Lihua; Danish, Muhammad; AuYeung, Tung Wai; Lee, Jenny; Kwok, Timothy; Abrigo, Jill; Wei, Yingying; Lo, Cecilia; Fung, Erik
Article

Assessing and managing frailty in advanced heart failure: An International Society for Heart and Lung Transplantation consensus statement

Journal of Heart and Lung Transplantation, v. 43, (1), January 2024, p. 1-27
Denfeld, Quin E.; Jha, Sunita R.; Fung, Erik; Jaarsma, Tiny; Maurer, Mathew S.; Reeves, Gordon R.; Afilalo, Jonathan; Beerli, Nadine; Bellumkonda, Lavanya; De Geest, Sabina; Gorodeski, Eiran Z.; Joyce, Emer; Kobashigawa, Jon; Mauthner, Oliver; McDonagh, Julee; Uchmanowicz, Izabella; Dickson, Victoria Vaughan; Lindenfeld, JoAnn; Macdonald, Peter
Article

Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes Biobank

Diabetologia, v. 67, (5), February 2024, p. 837-849
Jin, Qiao; Yu, Weichuan; Ma, Ronald C. W.; Fung, Erik
Article

Early Metabolomic and Immunologic Biomarkers as Prognostic Indicators for COVID-19

Metabolites, v. 14, (7), July 2024, article number 380
Chen, Zigui; Fung, Erik; Wong, Chun-Kwok; Ling, Lowell; Lui, Grace; Lai, Christopher K. C.; Ng, Rita W. Y.; Sze, Ryan K. H.; Ho, Wendy C. S.; Hui, David S. C.; Chan, Paul K. S.
Article

Evaluating Immunoassay Detection of GDF11 and Cross-Reactivity with GDF8, and Comparative Analysis of Serum GDF11 Levels Across Frailty Classes in Community-Living Older Adults

Journal of Frailty and Aging, v. 13, (Supplement 1), 2024, p. S91-S92
Yu, Ka Man; Lau, Gloria H.W.; Hao, Yidan; Woo, Jean; Fung, Erik
Article

The Asian Fabry Cardiomyopathy High-Risk Screening Study 2 (ASIAN-FAME-2): Prevalence of Fabry Disease in Patients with Left Ventricular Hypertrophy

Journal of Clinical Medicine, v. 13, (13), July 2024, article number 3896
Leung, Sophia Po-Yee; Dougherty, Scott; Zhang, Xiao-Yu; Kam, Kevin K. H.; Chi, Wai-Kin; Chan, Joseph Y. S.; Fung, Erik; Wong, Jeffrey K. T.; Choi, Paul C. L.; Chan, David K. H.; Sheng, Bun; Lee, Alex Pui-Wai
Article

2023 5

Diagnosing Hypertrophic Cardiomyopathy in Athletes

Journal of the Hong Kong College of Cardiology, v. 30, (3), May 2023, p. 12-18
Srisukajorn, Chalisa; Jirakulaporn, Tamonwan M.; Huang, Helen C.; Fung, Erik; Teekakirikul, Polakit
Article

Divergent Survival Outcomes Associated with Elevated Branched-Chain Amino Acid Levels among Older Adults with or without Hypertension and Diabetes: A Validated, Prospective, Longitudinal Follow-Up Study

Biomolecules, v. 13, (8), August 2023, article number 1252
Fung, Erik; Ng, Kwan Hung; Kwok, Timothy; Lui, Leong-Ting; Palaniswamy, Saranya; Chan, Queenie; Lim, Lee-Ling; Wiklund, Petri; Xie, Suyi; Turner, Cheryl; Elshorbagy, Amany K.; Refsum, Helga; Leung, Jason C. S.; Kong, Alice P. S.; Chan, Juliana C. N.; Järvelin, Marjo-Riitta; Woo, Jean
Article

Heterozygous Filamin C Truncating Mutation Disrupts Cardiac Development And Function

Journal of Cardiac Failure, v. 29, (4), April 2023, p. 695-696
Guo, Donghao; Zhao, Hui; Fung, Erik
Article

Towards clinical application of GlycA and GlycB for early detection of inflammation associated with (pre)diabetes and cardiovascular disease: recent evidence and updates

Journal of Inflammation (United Kingdom), v. 20, (1), October 2023, article number 32
Fung, Erik; Chan, Eunice Y. S.; Ng, Kwan Hung; Yu, Ka Man; Li, Huijun; Wang, Yulan
Article

Towards understanding the link between gut microbiota and heart failure in the heart-gut axis

European Journal of Preventive Cardiology, v. 30, (12), September 2023, p. 1272-1273
Fung, Erik; Wilson Tang, W.H.
Article

2022 7

Asymptomatic left ventricular dysfunction and cardiopulmonary exercise testing for mortality risk prediction

European Journal of Preventive Cardiology, v. 29, (7), May 2022, p. 1156-1157
Fung, Erik; Lau, Gloria H.W.
Article

Differential risks for heart failure hospitalization following severe respiratory infection by common pathogens

European Journal of Preventive Cardiology, v. 29, (4), March 2022, p. E163-E166
Fung, Erik; Cheng, Ho Yu; Choi, Kai Chow; Hui, David S. C; Yang, Chen; Chair, Sek Ying
Article

Early risk of acute myocardial infarction following hospitalization for severe influenza infection in the middle-aged population of Hong Kong

PLoS ONE, v. 17, (8 August), August 2022, article number e0272661
Cheng, Ho Yu; Fung, Erik; Choi, Kai Chow; Zou, Hui Jing; Chair, Sek Ying
Article

Inotropic Support for End-Stage Heart Failure in the Ambulatory Setting

Journal of Cardiac Failure, v. 28, (Supplement), September 2022, p. 14
Fung, Erik
Article

Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Biomolecules, v. 12, (7), July 2022, article number 934
Xie, Suyi; Li, Qi; Luk, Andrea O. Y.; Lan, Hui-Yao; Chan, Paul K. S.; Bayés-Genís, Antoni; Chan, Francis K. L.; Fung, Erik
Article

Pulmonary Arterial Hypertension Management in Asia: State of the Art From Japan, and Next Steps

JACC: Asia, v. 2, (3), June 2022, p. 285-286
Fung, Erik
Article

Mortality hazard of hypertension and diabetes, and inversive effects of obesity and circulating branched-chain amino acids in old age

The Journal of Frailty & Aging, v. 11, (Supplement 1), April 2022, p. 1-45
Fung, Erik; Lui, Leong-Ting; Palaniswamy, Saranya; Chan, Queenie; Lim, Lee-Ling; Chan, Juliana C.N.; Kwok, Timothy; Kong, Alice P.S.; Järvelin, Marjo-Riitta; Woo, Jean
Conference paper

2021 9

Asian Pacific Society of Cardiology Consensus Recommendations for Pre-participation Screening in Young Competitive Athletes

European Cardiology Review, v. 16, November 2021, article number 26
Wang, Luokai; Yeo, Tee Joo; Tan, Benedict; Destrube, Bernard; Tong, Khim Leng; Tan, Swee Yaw; Chan, Gregory; Huang, Zijuan; Tan, Frankie; Wang, Yu Chen; Lee, Jong-Young; Fung, Erik; Mak, Gary Yiu Kwong; So, Raymond; Wanlapakorn, Chaisiri; Ambari, Ade Meidian; Cuenza, Lucky; Koh, Choong Hou; Tan, Jack Wei Chieh
Article

Characterising frailty, metrics of continuous glucose monitoring, and mortality hazards in older adults with type 2 diabetes on insulin therapy (HARE): a prospective, observational cohort study

The Lancet Healthy Longevity, v. 2, (11), November 2021, p. e724-e735
Fung, Erik; Lui, Leong-Ting; Huang, Lei; Cheng, King Fai; Lau, Gloria H W; Chung, Yi Ting; Ahmadabadi, Behzad Nasiri; Xie, Suyi; Lee, Jenny S W; Hui, Elsie; So, Wing Yee; Sung, Joseph J Y; King, Irwin; Goggins, William B; Chan, Queenie; Järvelin, Marjo-Riitta; Ma, Ronald C W; Chow, Elaine; Kwok, Timothy
Article

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease

Human Genetics and Genomics Advances, v. 2, (3), July 2021, article number 100037
Teekakirikul, Polakit; Fung, Erik; Lo, Cecilia W.
Article

Functional Validation of a Pathogenic Missense Variant in Human Filamin C Cardiomyopathy through Disruption of a Zebrafish Homologue Recapitulates Cardiac Disease

The Journal of Heart and Lung Transplantation, v. 40, (4), April 2021, p. S237
Fung, Erik; Guo, D.; Zhu, W.; Ahmadabadi, B.N.; Lee, C.; Teekakirikul, P.; Zhao, H.
Article

Heart Failure with Reduced, Midrange and Preserved Ejection Fraction in Chinese with Type 2 Diabetes: Risk Factors and Prognosis

diabetes, v. 70, (Supplement 1), June 2021, article number 223-OR
Luk, Andrea; Zhang, Xinge; Fung, Erik; Wu, Hongjiang; Lau, Eric S.; Yang, Aimin; Chow, Elaine; Kong, Alice P.; Ma, Ronald C.; Chan, Juliana C.
Article

High prevalence of late-onset fabry cardiomyopathy in a cohort of 499 non-selective patients with left ventricular hypertrophy: The asian fabry cardiomyopathy high-risk screening study (asian-fame)

Journal of Clinical Medicine, v. 10, (10), May 2021, article number 2160
Fan, Yiting; Chan, Tsz-Ngai; Chow, Josie T. Y.; Kam, Kevin K. H.; Chi, Wai-Kin; Chan, Joseph Y. S.; Fung, Erik; Tong, Mabel M. P.; Wong, Jeffery K. T.; Choi, Paul C. L.; Chan, David K. H.; Sheng, Bun; Lee, Alex Pui-Wai
Article

Influenza-associated hospitalizations and risk of subsequent heart failure hospital admissions: A 20-year territorywide registry study in Hong Kong, China

American Journal of Epidemiology, v. 190, (5), May 2021, p. 779-785
Chair, Sek Ying; Cheng, Ho Yu; Choi, Kai Chow; Siow, Elaine K. C.; Cao, Xi; Fung, Erik
Article

Predicting 10-year mortality in older adults using VO₂max, oxygen uptake efficiency slope and frailty class

European Journal of Preventive Cardiology, v. 28, (10), October 2021, p. 1148-1151
Fung, Erik; Ting Lui, Leong; Gustafsson, Finn; Yau, Forrest C. F; Leung, Jason C. S; Wiklund, Petri; Järvelin, Marjo-Riitta; MacDonald, Peter S; Woo, Jean
Article

Towards early risk biomarkers: serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood

eBioMedicine, v. 72, October 2021, article number 103611
Ojanen, Xiaowei; Cheng, Runtan; Törmäkangas, Timo; Rappaport, Noa; Wilmanski, Tomasz; Wu, Na; Fung, Erik; Nedelec, Rozenn; Sebert, Sylvain; Vlachopoulos, Dimitris; Yan, Wei; Price, Nathan D.; Cheng, Sulin; Wiklund, Petri
Article

2020 11

A mutation in the filamin C gene causes diverse phenotypic expression in familial cardiomyopathies

Canadian Journal of Cardiology, v 36, (10), October 2020, p. S57-S58
Fung, Erik; Zhu, W.; Guo, D.; Ahmadabadi, B. Nasiri; Lee, C.; Teekakirikul, P.
Article

Alternative Hypothesis to Explain Disease Progression in Rheumatic Heart Disease

Circulation, v. 142, (22), December 2020, p. 2091-2094
Karthikeyan, Ganesan; Fung, Erik; Foo, Roger S.-Y.
Article

Cardiac Manifestations of Sarcopenia

Journal of Nutrition, Health and Aging, v. 24, (5), May 2020, p. 478-484
Yang, X.; Woo, Jean; Ting Lui, L.; Li, Q.; Fai Cheng, K.; Fan, Y.; Yau, F.; Lee, A.P.W.; Lee, J.S.W.; Fung, E.
Article

Circulating branched-chain amino acids and incident heart failure in type 2 diabetes: The Hong Kong Diabetes Register

Diabetes/Metabolism Research and Reviews, v. 36, (3), March 2020, article number e3253
Lim, Lee-Ling; Lau, Eric S.H.; Fung, Erik; Lee, Heung-Man; Ma, Ronald C.W.; Tam, Claudia H.T.; Wong, Willy K.K.; Ng, Alex C.W.; Chow, Elaine; Luk, Andrea O.Y.; Jenkins, Alicia; Chan, Juliana C.N.; Kong, Alice P.S.
Article

Cross-sectional analysis of 6-minute walk distance and diastolic function in a Hong Kong cohort of community-living older adults

European Heart Journal, v. 41, (Supplementary 1), January 2020, article number P39
Yang, X.; Lui, L.T.; Li, Q.; Cheng, K.F.; Liu, S.; Yau, F.; Sahota, D.; Fan, Y.; Lee, A.P.W.; Woo, J.; Fung, Erik
Article

Demographic and Echocardiographic Predictors of Later-onset Cardiac Variant of Fabry Disease Among Chinese Patients With Left Ventricular Hypertrophy

Circulation, v. 142, (Supplementary 3), November 2020
Chan, Tsz Ngai; Chow, Josie Tsz ying; Kam, Kevin Ka Ho; Sheng, Bun; Fan, Yiting; Wong, Ka Tak; Mabel, Tong Mei Po; Choi, Paul CL; Fung, Erik; Chan, Joseph YS; Chi, Wai Kin; Lee, Alex Pui-Wai
Article

Dual Biomarker Approach To Distinguish Cardiac And Non-cardiac Frailty

The Journal of Frailty & Aging, v. 9, (Supplement 1), March 2020, p. 46-179
Fung, Erik; Li, Qi; Xie, Suyi; Lui, Leong Ting; Woo, Jean
Article

Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy

Journal of Cellular and Molecular Medicine, v. 24, (22), November 2020, p. 13093-13103
Ni, Jun; Yang, Fuye; Huang, Xiao-Ru; Meng, Jinxiu; Chen, Jiaoyi; Bader, Michael; Penninger, Josef M.; Fung, Erik; Yu, Xue-Qing; Lan, Hui-Yao
Article

Elevated GDF-15 levels may indicate malnutrition in chronic compensated heart failure with or without diabetes mellitus

European Heart Journal, v. 41, Supplement 2, November 2020, p. 1169
Xie, S.; Lui, L.T.; Ma, R.C.W.; Graham, C.A.; Chan, P.K.S.; Chan, F.K.L.; Fung, Erik
Article

Growth Differentiation Factor 15 As a Composite Diabetic Cardiovascular Disease Indicator Including Heart Failure: A Systematic Review and Meta-Analysis

Journal of Cardiac Failure, v. 26, (10), October 2020, p. S17
Xie, Suyi; Li, Qi; Fung, Erik
Article

Screening for Fabry Disease in patients with unexplained left ventricular hypertrophy

PLoS ONE, v. 15, (9 September), September 2020, article number e0239675
Sadasivan, Chandu; Chow, Josie T.Y.; Sheng, Bun; Chan, David K.H.; Fan, Yiting; Choi, Paul C.L.; Wong, Jeffrey K.T.; Tong, Mabel M.B.; Chan, Tsz-Ngai; Fung, Erik; Kam, Kevin K.H.; Chan, Joseph Y.S.; Chi, Wai-Kin; Paterson, D. Ian; Senaratne, Manohara; Brass, Neil; Oudit, Gavin Y.; Lee, Alex P.W.
Article

2019 13

Analysis of survival associated with pulmonary arterial hypertension in patients with systemic lupus erythematosus

Annals of the Rheumatic Diseases, v. 78, (Supplement 2), June 2019, article number THU0264, p. 410
Ho, Chi; Fung, Erik; Tam, Lai-Shan
Article

Association analysis of N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) and growth differentiation factor 15 (GDF-15) in cardiac and non-cardiac frailty

European Journal of Heart Failure, v. 21, (S1), May 2019, p. 428-429
Li, Qi; Lui , Leong Ting; Yang, Xiaobo; Liu, Simin; Cheng, King Fai; Lupón, Josep; Bayés-Genís, Antoni; Sahota, Daljit; Woo, Jean; Fung, Erik
Article

Cardiomems^TM in VAD patients

Heart Asia, v. 11, (Supplement 1), August 2019, article number 26, p. A2
Fung, Erik
Article

Early Unplanned Readmissions After Admission to Hospital With Heart Failure

American Journal of Cardiology, v. 124, (5), September 2019, p. 736-745
Kwok, Chun Shing; Seferovic, Petar M; Van Spall, Harriette GC; Helliwell, Toby; Clarson, L.; Lawson, Claire; Kontopantelis, Evangelos; Patwala, Ashish; Duckett, S.; Fung, Erik; Mallen, Christian D; Mamas, Mamas A
Article

Fabry disease in east asia

Heart Asia, v. 11, (Supplement 1), August 2019, article number 31
Lee, Alex PW; Kam, Kevin KH; Fung, Erik; Chow, Josie; Fan, Yiting; Teekakirikul, Polakit; Wong, Katak; Chan, Joseph YS; Chan, David; Sheng, Bun
Article

Frailty, Diastolic Dysfunction, And Latent Heart Failure In The Community-living Elderly In Hong Kong: Cross-sectional Findings From The Ufo Study

Journal of the American College of Cardiology, v. 73, (9), March 2019, p. 1873
Fung, Erik; Yang, Xiaobo; Lui, Leong Ting; Li, Qi; Cheng, King Fai; Sahota, Daljit; Fan, Yiting; Lee, Jenny S.W.; Lee, Alex P.W.; Hui, Elsie; Woo, Jean
Article

Hypertrophic cardiomyopathy: An overview of genetics and management

Biomolecules, v. 9, (12), December 2019, article number 878
Teekakirikul, Polakit; Zhu, Wenjuan; Huang, Helen C.; Fung, Erik
Article

Multifaceted Functions of Epithelial Na+ Channel in Modulating Blood Pressure

Hypertension, v. 73, (2), February 2019, p. 273-281
Li, Qi; Fung, Erik
Article

Optimising heart failure care by multi-disciplinary heart failure clinic (MHFC)

Heart Asia, v. 11, (Supplement 1), August 2019, article number 5, p. A2
Kam, Kevin KH; Yu, Ada; Fung, Erik; Lee, Alex PW
Article

Peak Oxygen Uptake, Oxygen Uptake Efficiency Slope, And 6-minute Walk Distance Can Predict Long-term Survival In Community-based Nonfrail Older Adults

Canadian Journal of Cardiology, v. 35, (10), October 2019, p. S60-S61
Fung, Erik; Woo, J.; Leung, J.; Yau, F.
Article

Sarcopenia and reduced physical fitness are associated with cardiac dysfunction in community-living older adults

European Journal of Heart Failure, v. 21, (S1), May 2019, p. 535
Yang, Xiaobo; Lui, Leong Ting; Qi, Li; Cheng, King Fai; Liu, Simin; Yau, Forrest; Fan, Yiting; Lee, Alex P.W.; Woo, Jean; Fung, Erik
Article

Use of direct oral anticoagulant in atrial fibrillation with gastrointestinal bleeding: Balancing gastrointestinal safety and cardiovascular risks

Journal of Gastroenterology and Hepatology (Australia), v. 34, (6), June 2019, p. 959-960
Sung, Joseph JY; Fung, Erik
Article

Utility of the FRAIL Questionnaire in Detecting Heart Failure with Preserved Ejection Fraction

Journal of Nutrition, Health and Aging, v. 23, (4), April 2019, p. 373-377
Woo, Jean; Yang, X.; Lui, L. Tin; Li, Q.; Cheng, K. Fai; Fan, Y.; Yau, F.; Lee, A.P.W.; Lee, J.S.W.; Fung, Erik
Article

2018 9

#Frailty: A snapshot Twitter report on frailty knowledge translation

Australasian Journal on Ageing, v. 37, (4), December 2018, p. 309-312
Jha, Sunita R; McDonagh, Julee; Prichard, Ros; Newton, Phillip J; Hickman, Louise D; Fung, Erik; Macdonald, Peter S; Ferguson, Caleb
Article

Anticoagulation for mechanical circulatory support

Heart Asia, v. 10, (Supplement 1), 2018-11, article number 23, p. A6
Fung, Erik
Article

Association between oxygen uptake efficiency slope (OUES), an effort-independent measure of cardiorespiratory fitness (VO2max), and robust/pre-frail status in an elderly Chinese population

European Journal of Heart Failure, v. 20, (S1), May 2018, p. 528-529
Fung, Erik; Lui, Leong Ting; Yau, Forrest; Leung, Jason; Woo, Jean
Article

Comorbidities, fragility, and quality of life in heart failure patients with midrange ejection fraction

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, v. 2, (2), June 2018, article number 176
Gastelurrutia, Paloma; Lupon, Josep; Moliner, Pedro; Yang, Xiaobo; Cediel, German; de Antonio, Marta; Domingo, Mar; Altimir, Salvador; González, Beatriz; Rodríguez, Margarita; Rivas, Carmen; Díaz, Violeta; Fung, Erik; Zamora, Elisabet; Santesmases, Javier; Núñez, Julio; Woo, Jean; Bayes-Genis, Antoni
Article

Heart failure and frailty in the community-living elderly population: What the UFO study will tell us

Frontiers in Physiology, v. 9, (APR), April 2018, article number 347
Fung, Erik; Hui, Elsie; Yang, Xiaobo; Lui, Leong T.; Cheng, King F.; Li, Qi; Fan, Yiting; Sahota, Daljit S.; Ma, Bosco H.M.; Lee, Jenny S.W.; Lee, Alex P.W.; Woo, Jean
Article

Impact of frailty on mortality and hospitalization in chronic heart failure: A systematic review and meta-analysis

Journal of the American Heart Association, v. 7, (23), December 2018, article number e008251
Yang, Xiaobo; Lupón, Josep; Vidán, Maria T.; Ferguson, Caleb; Gastelurrutia, Paloma; Newton, Phillip J.; Macdonald, Peter S.; Bueno, Héctor; Bayés-Genís, Antoni; Woo, Jean; Fung, Erik
Article

Letter by Fung et al Regarding Article, “Frailty and Clinical Outcomes in Heart Failure: A Systematic Review and Meta-analysis”

Journal of the American Medical Directors Association, v. 19, (12), December 2018, p. 1143-1146
Fung, Erik; Yang, Xiaobo; Newton, Phillip J.; Ferguson, Caleb; Gastelurrutia, Paloma; Lupón, Josep; Bayés-Genís, Antoni; Jha, Sunita; Macdonald, Peter S.
Article

Performance Of Cardiopulmonary Exercise Capacity And Physical Fitness Indicators In Differentiating Pre-frail And Robust Elderly

Canadian Journal of Cardiology, v. 34, (10), October 2018, p. S6-S7
Fung, Erik; Lui, L.; Leung, J.; Woo, J.
Article

Supportive cardiology: an innovative practice model to integrate palliative care into the management of advanced heart failure

Heart Asia, v. 10, (Supplementary 1), November 2018, article number 22, p. A7
Yu, Doris; Li, Polly; Fung, Erik; Yuen, Jacqueline; Woo, Jean; Chair, SY; Lee, Vivian; Choi, KC; Lo, Raymond
Article

2017 6

C-reactive protein and ageing

Clinical and Experimental Pharmacology and Physiology, v. 44, December 2017, article number 12758, p. 9-14
Tang, Ying; Fung, Erik; Xu, Anping; Lan, Hui-Yao
Article

Deletion of angiotensin-converting enzyme-2 promotes hypertensive nephropathy by targeting smad7 for ubiquitin degradation

Hypertension, v. 70, (4), October 2017, p. 822-830
Liu, Zhen; Huang, Xiao-Ru; Chen, Hai-Yong; Fung, Erik; Liu, Jian; Lan, Hui-Yao
Article

Frailty, co-morbidities and survival in heart failure patients with mid-range ejection fraction

European Heart Journal, v. 38, (Supplement 1), August 2017, p. 111-111
Moliner, P.; Gastelurrutia, P.; Lupon, J.; Yang, X.; De Antonio, M.; Domingo, M.; Altimir, S.; Gonzalez, B.; Rodriguez, M.; Rivas, C.; Fung, Erik; Zamora, E.; Santesmases, J.; Woo, J.; Bayes-Genis, A.
Article

Risks of mortality and hospitalisation in patients with frailty and chronic heart failure: systematic review and meta-analysis

European Heart Journal, v. 38, (Supplement 1), August 2017, article number P4379, p. 906-907
Yang, X.; Lupon, J.; Gastelurrutia, P.; Newton, P.; Bueno, H.; Bayes-Genis, A.; Woo, J.; Fung, Erik
Article

The incidence, risk factors and in-hospital mortality of acute kidney injury in patients after abdominal aortic aneurysm repair surgery

BMC Nephrology, v. 18, (1), May 2017, article number 184
Tang, Ying; Chen, Junzhe; Huang, Kai; Luo, Dan; Liang, Peifen; Feng, Min; Chai, Wenxin; Fung, Erik; Lan, Hui Yao; Xu, Anping
Article

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

Scientific Reports, v. 7, (1), December 2017, article number 1481
Yang, Chen; Huang, Xiao-Ru; Fung, Erik; Liu, Hua-Feng; Lan, Hui-Yao
Article

2016 2

Fulminant eosinophilic myocarditis following ICD implantation in a patient with undisclosed nickel allergy

International Journal of Cardiology, v. 203, January 2016, p. 1018-1019
Fung, Erik; Fong, Michael W.; Correa, Adrian J.; Yoon, Andrew J.; Grazette, Luanda P.
Article

Prevalence of LVAD Items Available for Sale on eBay in the US and Other Countries

Journal of Cardiac Failure, v. 22, (8), August 2016, article number 345, p. S120
Fung, Erik; Grazette, Luanda; Saxon, Leslie; Bowdish, Michael; Yoon, Andrew J.
Article

2015 3

Electrocardiographic patch devices and contemporary wireless cardiac monitoring

Frontiers in Physiology, v. 6, (MAY), May 2015, article number 149
Fung, Erik; Järvelin, Marjo-Riitta; Doshi, Rahul N.; Shinbane, Jerold S.; Carlson, Steven K.; Grazette, Luanda P.; Chang, Philip M.; Sangha, Rajbir S.; Huikuri, Heikki V.; Peters, Nicholas S.
Article

Evolution from electrophysiologic to hemodynamic monitoring: The story of left atrial and pulmonary artery pressure monitors

Frontiers in Physiology, v. 6, (OCT), October 2015, article number 271
Mooney, Deirdre M.; Fung, Erik; Doshi, Rahul N.; Shavelle, David M.
Article

Meta-analysis of randomized controlled trials of genotype-guided vs standard dosing of warfarin

Chest, v. 148, (3), September 2015, p. 701-710
Dahal, Khagendra; Sharma, Sharan P.; Fung, Erik; Lee, Juyong; Moore, Jason H.; Unterborn, John N.; Williams, Scott M.
Article

2014 1

Infant locomotive development and its association with adult blood pressure

European Journal of Pediatrics, v. 173, (10), September 2014, p. 1309-1317
Pillas, Demetris; Fung, Erik; Jarvelin, Marjo-Riitta
Article

2012 2

Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin

Seminars in Thrombosis and Hemostasis, v. 38, (8), November 2012, p. 893-904
Fung, Erik; Patsopoulos, Nikolaos A.; Belknap, Steven M.; O'Rourke, Daniel J.; Robb, John F.; Anderson, Jeffrey L.; Shworak, Nicholas W.; Moore, Jason H.
Article

Macrophages in collateral arteriogenesis

Frontiers in Physiology, v. 3 SEP, September 2012, article number 353
Fung, Erik; Helisch, Armin
Article

2010 1

Multiplexed immunophenotyping of human antigen-presenting cells in whole blood by polychromatic flow cytometry

Nature Protocols, v. 5, (6), February 2010, p. 357-370
Fung, Erik; Esposito, Laura; Todd, John A.; Wicker, Linda S.
Article

2009 4

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

Genes and Immunity, v. 10, (2), March 2009, p. 188-191
Fung, Erik; Smyth, D.J.; Howson, J.M.M.; Cooper, J.D.; Walker, N.M.; Stevens, H.; Wicker, L.S.; Todd, J.A.
Article

Cell-specific CD25 Expression is Determined by Type 1 Diabetes Associated IL2RA Haplotypes

Clinical Immunology, v. 131, (Supplement), April 2009, p. S94
Dendrou, Calliope; Plagnol, Vincent; Fung, Erik; Downes, Kate; Cooper, Jason; Nutland, Sarah; Coleman, Gillian; Himsworth, Matthew; Hardy, Matthew; Burren, Oliver; Healy, Barry; Walker, Neil; Koch, Kerstin; Ouwehand, Willem; Wareham, Nicholas; Todd, John; Wicker, Linda
Article

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

Nature Genetics, v. 41, (9), August 2009, p. 1011-1015
Dendrou, Calliope A; Plagnol, Vincent; Fung, Erik; Yang, Jennie H M; Downes, Kate; Cooper, Jason D; Nutland, Sarah; Coleman, Gillian; Himsworth, Matthew; Hardy, Matthew; Burren, Oliver; Healy, Barry; Walker, Neil M; Koch, Kerstin; Ouwehand, Willem H; Bradley, John R; Wareham, Nicholas J; Todd, John A; Wicker, Linda S
Article

Fluorescence Intensity Normalisation: Correcting for Time Effects in Large-Scale Flow Cytometric Analysis

Advances in Bioinformatics, v. 2009, (1), November 2009, article number 476106
Dendrou, Calliope A.; Fung, Erik; Esposito, Laura; Todd, John A.; Wicker, Linda S.; Plagnol, Vincent
Article

2007 3

Delta-like 4 induces Notch signaling in macrophages: Implications for inflammation

Circulation, v. 115, (23), June 2007, p. 2948-2956
Fung, Erik; Tang, Sai-Man Timothy; Canner, James P.; Morishige, Kunio; Arboleda-Velasquez, Joseph F.; Cardoso, Angelo A.; Carlesso, Nadia; Aster, Jon C.; Aikawa, Masanori
Article

Monocyte biomarkers in autoimmune type 1 diabetes

Acta Diabetologica, v. 44, November 2007, p. S17
Fung, Erik; Plagnol, Vincent; Healy, Barry; Burren, Oliver; Todd, John A.; Wicker, Linda S.
Article

Monocyte immunophenotypes in type 1 diabetes

Clinical Immunology, v. 123, (S), 2007, p. S19-S20
Fung, Erik; Todd, John A.; Wicker, Linda S.
Article

2005 3

CADASIL mutations impair Notch3 glycosylation by Fringe

Human Molecular Genetics, v. 14, (12), June 2005, p. 1631-1639
Arboleda-Velasquez, Joseph F.; Rampal, Raajit; Fung, Erik; Darland, Diane C.; Liu, Min; Martinez, Maria C.; Donahue, Christine P.; Navarro-Gonzalez, Manuel F.; Libby, Peter; D'Amore, Patricia A.; Aikawa, Masanori; Haltiwanger, Robert S.; Kosik, Kenneth S.
Article

Interleukin-1β is a novel target of Notch signaling in macrophages

Circulation, v. 112, (17), October 2005, p. U56
Morishige, Kunio; Tang, S.M. Timothy; Fung, Erik; Aster, Jon C.; Aikawa, Masanori
Article

The potential use of type-5 phosphodiesterase inhibitors in coronary artery bypass graft surgery

Chest, v. 128, (4), October 2005, p. 3065-3073
Fung, Erik; Fiscus, Ronald R.; Yim, Anthony P. C.; Angelini, Gianni D.; Arifi, Ahmed A.
Article

2004 1

Induction of the Notch pathway in activated human macrophages

Circulation, v. 110, (17), October 2004, p. 274
Fung, Erik; Arboleda-Velasquez, Joseph; Deguchi, Jun-o; Libby, Peter; Kosik, Kenneth S.; Aikawa, Masanori
Article

2003 1

Adrenomedullin induces direct (endothelium-independent) vasorelaxations and cyclic adenosine monophosphate elevations that are synergistically enhanced by brain natriuretic peptide in isolated rings of rat thoracic aorta

Journal of Cardiovascular Pharmacology, v. 41, (6), June 2003, p. 849-855
Fung, Erik; Fiscus, Ronald R.
Article

2002 1

Brain Natriuretic Peptide (BNP)-Induced Cyclic GMP Elevations Synergistically Enhance the Vasodilatory and Cyclic AMP Responses to Adrenomedullin in Rat Aortic Rings

Journal of Cardiac Surgery, v. 17, (6), November 2002, article number 101423, p. 565-566
Fung, Erik; Fiscus, Ronald R
Article

2001 1

Synergistic potentiation of adrenomedullin-induced vasorelaxations and cAMP elevations by brain natriuretic peptide (BNP) in endothelium-denuded rat thoracic aorta

Cell Biology International, v. 25, 2001, p. 1052
Fung, Erik; Fiscus, Ronald R.
Article

Article 5

Consolidating Concepts From Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management

Journal of Cardiac Failure, v. 137, (1), June 2025, p. 1-10
Lau, Gloria H.W.; Auyeung, Tung Wai; Joyce, Emer; McDonagh, Julee; Yu, Ka Man; Woo, Jean; Lee, Jenny S.W.; Jha, Sunita; MacDonald, Peter S.; Fung, Erik

Effects of recombinant GDF15 pretreatment on mitochondrial damage and cytotoxicity induced by doxorubicin in human stem cell-derived cardiomyocytes

European Journal of Heart Failure, v. 27, (S1), March 2025, article number 21
Fung, Erik; Luo, H.; Chen, JCH; Poon, E.

eSports, exergames, and eAthletes: opportunities and challenges for preventive cardiology on a global scale

European Journal of Preventive Cardiology, v. 32, (1), January 2025, p. 88-90
Fung, Erik; Pelliccia, Antonio

Modeling of G2151S Missense Mutation in Filamin C Cardiomyopathy Reveals Alteration in Phosphorylation Affecting Binding with FILIP1

The Journal of Heart and Lung Transplantation, v. 44, (4), April 2025, p. S221-S222
Zhang, X.; Guo, D.; Zhao, H.; Yang, D.; Fung, Erik

NT-proBNP improves prediction of cardiorenal complications in type 2 diabetes: the Hong Kong Diabetes Biobank

Diabetologia, v. 68, (2), February 2025, p. 342-356
Ma, Ronald C. W.; Tam, Claudia H. T.; Hou, Yong; Lau, Eric S. H.; Ozaki, Risa; Lui, Juliana N. M.; Chow, Elaine; Kong, Alice P. S.; Huang, Chuiguo; Ng, Alex C. W.; Fung, Erik G.; Luk, Andrea O. Y.; So, Wing Yee; Lim, Cadmon K. P.; Chan, Juliana C. N.

Conference paper 3

Effects of recombinant GDF15 pretreatment on mitochondrial damage and cytotoxicity induced by doxorubicin in human stem cell-derived cardiomyocytes

European Journal of Heart Failure Supplements, June 2025
Fung, Erik; Luo, H.; Chen, JCH; Poon, E.

Effects of recombinant GDF15 pretreatment on mitochondrial damage and cytotoxicity induced by doxorubicin in human stem cell-derived cardiomyocytes

N/A / European Society of Cardiology (ESC). European Society of Cardiology (ESC), 2025
Fung, Erik

Portable Electrical Impedance Tomography Enables Heart Ejection Fraction Measurement for Health Screening in Nonspecialist Settings

2025 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2025) / Institute of Electrical and Electronics Engineers. Institute of Electrical and Electronics Engineers, 2025
Lawson, Michael; Lui, Henry; Huen, Vicky; Chan, Kannie W.Y.; Chan, Kevin C.; Wong, Eddie C.; Fung, Erik; Chan, Russell W.

Article 6

A Longitudinal 20-year Analysis Indicates Acceleration of Cardiometabolic Comorbidities on Dementia Risk

Circulation, v. 150, (Supplement 1), November 2024
Huang, Lihua; Danish, Muhammad; AuYeung, Tung Wai; Lee, Jenny; Kwok, Timothy; Abrigo, Jill; Wei, Yingying; Lo, Cecilia; Fung, Erik

Assessing and managing frailty in advanced heart failure: An International Society for Heart and Lung Transplantation consensus statement

Journal of Heart and Lung Transplantation, v. 43, (1), January 2024, p. 1-27
Denfeld, Quin E.; Jha, Sunita R.; Fung, Erik; Jaarsma, Tiny; Maurer, Mathew S.; Reeves, Gordon R.; Afilalo, Jonathan; Beerli, Nadine; Bellumkonda, Lavanya; De Geest, Sabina; Gorodeski, Eiran Z.; Joyce, Emer; Kobashigawa, Jon; Mauthner, Oliver; McDonagh, Julee; Uchmanowicz, Izabella; Dickson, Victoria Vaughan; Lindenfeld, JoAnn; Macdonald, Peter

Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes Biobank

Diabetologia, v. 67, (5), February 2024, p. 837-849
Jin, Qiao; Yu, Weichuan; Ma, Ronald C. W.; Fung, Erik

Early Metabolomic and Immunologic Biomarkers as Prognostic Indicators for COVID-19

Metabolites, v. 14, (7), July 2024, article number 380
Chen, Zigui; Fung, Erik; Wong, Chun-Kwok; Ling, Lowell; Lui, Grace; Lai, Christopher K. C.; Ng, Rita W. Y.; Sze, Ryan K. H.; Ho, Wendy C. S.; Hui, David S. C.; Chan, Paul K. S.

Evaluating Immunoassay Detection of GDF11 and Cross-Reactivity with GDF8, and Comparative Analysis of Serum GDF11 Levels Across Frailty Classes in Community-Living Older Adults

Journal of Frailty and Aging, v. 13, (Supplement 1), 2024, p. S91-S92
Yu, Ka Man; Lau, Gloria H.W.; Hao, Yidan; Woo, Jean; Fung, Erik

The Asian Fabry Cardiomyopathy High-Risk Screening Study 2 (ASIAN-FAME-2): Prevalence of Fabry Disease in Patients with Left Ventricular Hypertrophy

Journal of Clinical Medicine, v. 13, (13), July 2024, article number 3896
Leung, Sophia Po-Yee; Dougherty, Scott; Zhang, Xiao-Yu; Kam, Kevin K. H.; Chi, Wai-Kin; Chan, Joseph Y. S.; Fung, Erik; Wong, Jeffrey K. T.; Choi, Paul C. L.; Chan, David K. H.; Sheng, Bun; Lee, Alex Pui-Wai

Article 5

Diagnosing Hypertrophic Cardiomyopathy in Athletes

Journal of the Hong Kong College of Cardiology, v. 30, (3), May 2023, p. 12-18
Srisukajorn, Chalisa; Jirakulaporn, Tamonwan M.; Huang, Helen C.; Fung, Erik; Teekakirikul, Polakit

Divergent Survival Outcomes Associated with Elevated Branched-Chain Amino Acid Levels among Older Adults with or without Hypertension and Diabetes: A Validated, Prospective, Longitudinal Follow-Up Study

Biomolecules, v. 13, (8), August 2023, article number 1252
Fung, Erik; Ng, Kwan Hung; Kwok, Timothy; Lui, Leong-Ting; Palaniswamy, Saranya; Chan, Queenie; Lim, Lee-Ling; Wiklund, Petri; Xie, Suyi; Turner, Cheryl; Elshorbagy, Amany K.; Refsum, Helga; Leung, Jason C. S.; Kong, Alice P. S.; Chan, Juliana C. N.; Järvelin, Marjo-Riitta; Woo, Jean

Heterozygous Filamin C Truncating Mutation Disrupts Cardiac Development And Function

Journal of Cardiac Failure, v. 29, (4), April 2023, p. 695-696
Guo, Donghao; Zhao, Hui; Fung, Erik

Towards clinical application of GlycA and GlycB for early detection of inflammation associated with (pre)diabetes and cardiovascular disease: recent evidence and updates

Journal of Inflammation (United Kingdom), v. 20, (1), October 2023, article number 32
Fung, Erik; Chan, Eunice Y. S.; Ng, Kwan Hung; Yu, Ka Man; Li, Huijun; Wang, Yulan

Towards understanding the link between gut microbiota and heart failure in the heart-gut axis

European Journal of Preventive Cardiology, v. 30, (12), September 2023, p. 1272-1273
Fung, Erik; Wilson Tang, W.H.

Article 6

Asymptomatic left ventricular dysfunction and cardiopulmonary exercise testing for mortality risk prediction

European Journal of Preventive Cardiology, v. 29, (7), May 2022, p. 1156-1157
Fung, Erik; Lau, Gloria H.W.

Differential risks for heart failure hospitalization following severe respiratory infection by common pathogens

European Journal of Preventive Cardiology, v. 29, (4), March 2022, p. E163-E166
Fung, Erik; Cheng, Ho Yu; Choi, Kai Chow; Hui, David S. C; Yang, Chen; Chair, Sek Ying

Early risk of acute myocardial infarction following hospitalization for severe influenza infection in the middle-aged population of Hong Kong

PLoS ONE, v. 17, (8 August), August 2022, article number e0272661
Cheng, Ho Yu; Fung, Erik; Choi, Kai Chow; Zou, Hui Jing; Chair, Sek Ying

Inotropic Support for End-Stage Heart Failure in the Ambulatory Setting

Journal of Cardiac Failure, v. 28, (Supplement), September 2022, p. 14
Fung, Erik

Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Biomolecules, v. 12, (7), July 2022, article number 934
Xie, Suyi; Li, Qi; Luk, Andrea O. Y.; Lan, Hui-Yao; Chan, Paul K. S.; Bayés-Genís, Antoni; Chan, Francis K. L.; Fung, Erik

Pulmonary Arterial Hypertension Management in Asia: State of the Art From Japan, and Next Steps

JACC: Asia, v. 2, (3), June 2022, p. 285-286
Fung, Erik

Conference paper 1

Mortality hazard of hypertension and diabetes, and inversive effects of obesity and circulating branched-chain amino acids in old age

The Journal of Frailty & Aging, v. 11, (Supplement 1), April 2022, p. 1-45
Fung, Erik; Lui, Leong-Ting; Palaniswamy, Saranya; Chan, Queenie; Lim, Lee-Ling; Chan, Juliana C.N.; Kwok, Timothy; Kong, Alice P.S.; Järvelin, Marjo-Riitta; Woo, Jean

Article 9

Asian Pacific Society of Cardiology Consensus Recommendations for Pre-participation Screening in Young Competitive Athletes

European Cardiology Review, v. 16, November 2021, article number 26
Wang, Luokai; Yeo, Tee Joo; Tan, Benedict; Destrube, Bernard; Tong, Khim Leng; Tan, Swee Yaw; Chan, Gregory; Huang, Zijuan; Tan, Frankie; Wang, Yu Chen; Lee, Jong-Young; Fung, Erik; Mak, Gary Yiu Kwong; So, Raymond; Wanlapakorn, Chaisiri; Ambari, Ade Meidian; Cuenza, Lucky; Koh, Choong Hou; Tan, Jack Wei Chieh

Characterising frailty, metrics of continuous glucose monitoring, and mortality hazards in older adults with type 2 diabetes on insulin therapy (HARE): a prospective, observational cohort study

The Lancet Healthy Longevity, v. 2, (11), November 2021, p. e724-e735
Fung, Erik; Lui, Leong-Ting; Huang, Lei; Cheng, King Fai; Lau, Gloria H W; Chung, Yi Ting; Ahmadabadi, Behzad Nasiri; Xie, Suyi; Lee, Jenny S W; Hui, Elsie; So, Wing Yee; Sung, Joseph J Y; King, Irwin; Goggins, William B; Chan, Queenie; Järvelin, Marjo-Riitta; Ma, Ronald C W; Chow, Elaine; Kwok, Timothy

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease

Human Genetics and Genomics Advances, v. 2, (3), July 2021, article number 100037
Teekakirikul, Polakit; Fung, Erik; Lo, Cecilia W.

Functional Validation of a Pathogenic Missense Variant in Human Filamin C Cardiomyopathy through Disruption of a Zebrafish Homologue Recapitulates Cardiac Disease

The Journal of Heart and Lung Transplantation, v. 40, (4), April 2021, p. S237
Fung, Erik; Guo, D.; Zhu, W.; Ahmadabadi, B.N.; Lee, C.; Teekakirikul, P.; Zhao, H.

Heart Failure with Reduced, Midrange and Preserved Ejection Fraction in Chinese with Type 2 Diabetes: Risk Factors and Prognosis

diabetes, v. 70, (Supplement 1), June 2021, article number 223-OR
Luk, Andrea; Zhang, Xinge; Fung, Erik; Wu, Hongjiang; Lau, Eric S.; Yang, Aimin; Chow, Elaine; Kong, Alice P.; Ma, Ronald C.; Chan, Juliana C.

High prevalence of late-onset fabry cardiomyopathy in a cohort of 499 non-selective patients with left ventricular hypertrophy: The asian fabry cardiomyopathy high-risk screening study (asian-fame)

Journal of Clinical Medicine, v. 10, (10), May 2021, article number 2160
Fan, Yiting; Chan, Tsz-Ngai; Chow, Josie T. Y.; Kam, Kevin K. H.; Chi, Wai-Kin; Chan, Joseph Y. S.; Fung, Erik; Tong, Mabel M. P.; Wong, Jeffery K. T.; Choi, Paul C. L.; Chan, David K. H.; Sheng, Bun; Lee, Alex Pui-Wai

Influenza-associated hospitalizations and risk of subsequent heart failure hospital admissions: A 20-year territorywide registry study in Hong Kong, China

American Journal of Epidemiology, v. 190, (5), May 2021, p. 779-785
Chair, Sek Ying; Cheng, Ho Yu; Choi, Kai Chow; Siow, Elaine K. C.; Cao, Xi; Fung, Erik

Predicting 10-year mortality in older adults using VO₂max, oxygen uptake efficiency slope and frailty class

European Journal of Preventive Cardiology, v. 28, (10), October 2021, p. 1148-1151
Fung, Erik; Ting Lui, Leong; Gustafsson, Finn; Yau, Forrest C. F; Leung, Jason C. S; Wiklund, Petri; Järvelin, Marjo-Riitta; MacDonald, Peter S; Woo, Jean

Towards early risk biomarkers: serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood

eBioMedicine, v. 72, October 2021, article number 103611
Ojanen, Xiaowei; Cheng, Runtan; Törmäkangas, Timo; Rappaport, Noa; Wilmanski, Tomasz; Wu, Na; Fung, Erik; Nedelec, Rozenn; Sebert, Sylvain; Vlachopoulos, Dimitris; Yan, Wei; Price, Nathan D.; Cheng, Sulin; Wiklund, Petri

Article 11

A mutation in the filamin C gene causes diverse phenotypic expression in familial cardiomyopathies

Canadian Journal of Cardiology, v 36, (10), October 2020, p. S57-S58
Fung, Erik; Zhu, W.; Guo, D.; Ahmadabadi, B. Nasiri; Lee, C.; Teekakirikul, P.

Alternative Hypothesis to Explain Disease Progression in Rheumatic Heart Disease

Circulation, v. 142, (22), December 2020, p. 2091-2094
Karthikeyan, Ganesan; Fung, Erik; Foo, Roger S.-Y.

Cardiac Manifestations of Sarcopenia

Journal of Nutrition, Health and Aging, v. 24, (5), May 2020, p. 478-484
Yang, X.; Woo, Jean; Ting Lui, L.; Li, Q.; Fai Cheng, K.; Fan, Y.; Yau, F.; Lee, A.P.W.; Lee, J.S.W.; Fung, E.

Circulating branched-chain amino acids and incident heart failure in type 2 diabetes: The Hong Kong Diabetes Register

Diabetes/Metabolism Research and Reviews, v. 36, (3), March 2020, article number e3253
Lim, Lee-Ling; Lau, Eric S.H.; Fung, Erik; Lee, Heung-Man; Ma, Ronald C.W.; Tam, Claudia H.T.; Wong, Willy K.K.; Ng, Alex C.W.; Chow, Elaine; Luk, Andrea O.Y.; Jenkins, Alicia; Chan, Juliana C.N.; Kong, Alice P.S.

Cross-sectional analysis of 6-minute walk distance and diastolic function in a Hong Kong cohort of community-living older adults

European Heart Journal, v. 41, (Supplementary 1), January 2020, article number P39
Yang, X.; Lui, L.T.; Li, Q.; Cheng, K.F.; Liu, S.; Yau, F.; Sahota, D.; Fan, Y.; Lee, A.P.W.; Woo, J.; Fung, Erik

Demographic and Echocardiographic Predictors of Later-onset Cardiac Variant of Fabry Disease Among Chinese Patients With Left Ventricular Hypertrophy

Circulation, v. 142, (Supplementary 3), November 2020
Chan, Tsz Ngai; Chow, Josie Tsz ying; Kam, Kevin Ka Ho; Sheng, Bun; Fan, Yiting; Wong, Ka Tak; Mabel, Tong Mei Po; Choi, Paul CL; Fung, Erik; Chan, Joseph YS; Chi, Wai Kin; Lee, Alex Pui-Wai

Dual Biomarker Approach To Distinguish Cardiac And Non-cardiac Frailty

The Journal of Frailty & Aging, v. 9, (Supplement 1), March 2020, p. 46-179
Fung, Erik; Li, Qi; Xie, Suyi; Lui, Leong Ting; Woo, Jean

Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy

Journal of Cellular and Molecular Medicine, v. 24, (22), November 2020, p. 13093-13103
Ni, Jun; Yang, Fuye; Huang, Xiao-Ru; Meng, Jinxiu; Chen, Jiaoyi; Bader, Michael; Penninger, Josef M.; Fung, Erik; Yu, Xue-Qing; Lan, Hui-Yao

Elevated GDF-15 levels may indicate malnutrition in chronic compensated heart failure with or without diabetes mellitus

European Heart Journal, v. 41, Supplement 2, November 2020, p. 1169
Xie, S.; Lui, L.T.; Ma, R.C.W.; Graham, C.A.; Chan, P.K.S.; Chan, F.K.L.; Fung, Erik

Growth Differentiation Factor 15 As a Composite Diabetic Cardiovascular Disease Indicator Including Heart Failure: A Systematic Review and Meta-Analysis

Journal of Cardiac Failure, v. 26, (10), October 2020, p. S17
Xie, Suyi; Li, Qi; Fung, Erik

Screening for Fabry Disease in patients with unexplained left ventricular hypertrophy

PLoS ONE, v. 15, (9 September), September 2020, article number e0239675
Sadasivan, Chandu; Chow, Josie T.Y.; Sheng, Bun; Chan, David K.H.; Fan, Yiting; Choi, Paul C.L.; Wong, Jeffrey K.T.; Tong, Mabel M.B.; Chan, Tsz-Ngai; Fung, Erik; Kam, Kevin K.H.; Chan, Joseph Y.S.; Chi, Wai-Kin; Paterson, D. Ian; Senaratne, Manohara; Brass, Neil; Oudit, Gavin Y.; Lee, Alex P.W.

Article 13

Analysis of survival associated with pulmonary arterial hypertension in patients with systemic lupus erythematosus

Annals of the Rheumatic Diseases, v. 78, (Supplement 2), June 2019, article number THU0264, p. 410
Ho, Chi; Fung, Erik; Tam, Lai-Shan

Association analysis of N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) and growth differentiation factor 15 (GDF-15) in cardiac and non-cardiac frailty

European Journal of Heart Failure, v. 21, (S1), May 2019, p. 428-429
Li, Qi; Lui , Leong Ting; Yang, Xiaobo; Liu, Simin; Cheng, King Fai; Lupón, Josep; Bayés-Genís, Antoni; Sahota, Daljit; Woo, Jean; Fung, Erik

Cardiomems^TM in VAD patients

Heart Asia, v. 11, (Supplement 1), August 2019, article number 26, p. A2
Fung, Erik

Early Unplanned Readmissions After Admission to Hospital With Heart Failure

American Journal of Cardiology, v. 124, (5), September 2019, p. 736-745
Kwok, Chun Shing; Seferovic, Petar M; Van Spall, Harriette GC; Helliwell, Toby; Clarson, L.; Lawson, Claire; Kontopantelis, Evangelos; Patwala, Ashish; Duckett, S.; Fung, Erik; Mallen, Christian D; Mamas, Mamas A

Fabry disease in east asia

Heart Asia, v. 11, (Supplement 1), August 2019, article number 31
Lee, Alex PW; Kam, Kevin KH; Fung, Erik; Chow, Josie; Fan, Yiting; Teekakirikul, Polakit; Wong, Katak; Chan, Joseph YS; Chan, David; Sheng, Bun

Frailty, Diastolic Dysfunction, And Latent Heart Failure In The Community-living Elderly In Hong Kong: Cross-sectional Findings From The Ufo Study

Journal of the American College of Cardiology, v. 73, (9), March 2019, p. 1873
Fung, Erik; Yang, Xiaobo; Lui, Leong Ting; Li, Qi; Cheng, King Fai; Sahota, Daljit; Fan, Yiting; Lee, Jenny S.W.; Lee, Alex P.W.; Hui, Elsie; Woo, Jean

Hypertrophic cardiomyopathy: An overview of genetics and management

Biomolecules, v. 9, (12), December 2019, article number 878
Teekakirikul, Polakit; Zhu, Wenjuan; Huang, Helen C.; Fung, Erik

Multifaceted Functions of Epithelial Na+ Channel in Modulating Blood Pressure

Hypertension, v. 73, (2), February 2019, p. 273-281
Li, Qi; Fung, Erik

Optimising heart failure care by multi-disciplinary heart failure clinic (MHFC)

Heart Asia, v. 11, (Supplement 1), August 2019, article number 5, p. A2
Kam, Kevin KH; Yu, Ada; Fung, Erik; Lee, Alex PW

Peak Oxygen Uptake, Oxygen Uptake Efficiency Slope, And 6-minute Walk Distance Can Predict Long-term Survival In Community-based Nonfrail Older Adults

Canadian Journal of Cardiology, v. 35, (10), October 2019, p. S60-S61
Fung, Erik; Woo, J.; Leung, J.; Yau, F.

Sarcopenia and reduced physical fitness are associated with cardiac dysfunction in community-living older adults

European Journal of Heart Failure, v. 21, (S1), May 2019, p. 535
Yang, Xiaobo; Lui, Leong Ting; Qi, Li; Cheng, King Fai; Liu, Simin; Yau, Forrest; Fan, Yiting; Lee, Alex P.W.; Woo, Jean; Fung, Erik

Use of direct oral anticoagulant in atrial fibrillation with gastrointestinal bleeding: Balancing gastrointestinal safety and cardiovascular risks

Journal of Gastroenterology and Hepatology (Australia), v. 34, (6), June 2019, p. 959-960
Sung, Joseph JY; Fung, Erik

Utility of the FRAIL Questionnaire in Detecting Heart Failure with Preserved Ejection Fraction

Journal of Nutrition, Health and Aging, v. 23, (4), April 2019, p. 373-377
Woo, Jean; Yang, X.; Lui, L. Tin; Li, Q.; Cheng, K. Fai; Fan, Y.; Yau, F.; Lee, A.P.W.; Lee, J.S.W.; Fung, Erik

Article 9

#Frailty: A snapshot Twitter report on frailty knowledge translation

Australasian Journal on Ageing, v. 37, (4), December 2018, p. 309-312
Jha, Sunita R; McDonagh, Julee; Prichard, Ros; Newton, Phillip J; Hickman, Louise D; Fung, Erik; Macdonald, Peter S; Ferguson, Caleb

Anticoagulation for mechanical circulatory support

Heart Asia, v. 10, (Supplement 1), 2018-11, article number 23, p. A6
Fung, Erik

Association between oxygen uptake efficiency slope (OUES), an effort-independent measure of cardiorespiratory fitness (VO2max), and robust/pre-frail status in an elderly Chinese population

European Journal of Heart Failure, v. 20, (S1), May 2018, p. 528-529
Fung, Erik; Lui, Leong Ting; Yau, Forrest; Leung, Jason; Woo, Jean

Comorbidities, fragility, and quality of life in heart failure patients with midrange ejection fraction

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, v. 2, (2), June 2018, article number 176
Gastelurrutia, Paloma; Lupon, Josep; Moliner, Pedro; Yang, Xiaobo; Cediel, German; de Antonio, Marta; Domingo, Mar; Altimir, Salvador; González, Beatriz; Rodríguez, Margarita; Rivas, Carmen; Díaz, Violeta; Fung, Erik; Zamora, Elisabet; Santesmases, Javier; Núñez, Julio; Woo, Jean; Bayes-Genis, Antoni

Heart failure and frailty in the community-living elderly population: What the UFO study will tell us

Frontiers in Physiology, v. 9, (APR), April 2018, article number 347
Fung, Erik; Hui, Elsie; Yang, Xiaobo; Lui, Leong T.; Cheng, King F.; Li, Qi; Fan, Yiting; Sahota, Daljit S.; Ma, Bosco H.M.; Lee, Jenny S.W.; Lee, Alex P.W.; Woo, Jean

Impact of frailty on mortality and hospitalization in chronic heart failure: A systematic review and meta-analysis

Journal of the American Heart Association, v. 7, (23), December 2018, article number e008251
Yang, Xiaobo; Lupón, Josep; Vidán, Maria T.; Ferguson, Caleb; Gastelurrutia, Paloma; Newton, Phillip J.; Macdonald, Peter S.; Bueno, Héctor; Bayés-Genís, Antoni; Woo, Jean; Fung, Erik

Letter by Fung et al Regarding Article, “Frailty and Clinical Outcomes in Heart Failure: A Systematic Review and Meta-analysis”

Journal of the American Medical Directors Association, v. 19, (12), December 2018, p. 1143-1146
Fung, Erik; Yang, Xiaobo; Newton, Phillip J.; Ferguson, Caleb; Gastelurrutia, Paloma; Lupón, Josep; Bayés-Genís, Antoni; Jha, Sunita; Macdonald, Peter S.

Performance Of Cardiopulmonary Exercise Capacity And Physical Fitness Indicators In Differentiating Pre-frail And Robust Elderly

Canadian Journal of Cardiology, v. 34, (10), October 2018, p. S6-S7
Fung, Erik; Lui, L.; Leung, J.; Woo, J.

Supportive cardiology: an innovative practice model to integrate palliative care into the management of advanced heart failure

Heart Asia, v. 10, (Supplementary 1), November 2018, article number 22, p. A7
Yu, Doris; Li, Polly; Fung, Erik; Yuen, Jacqueline; Woo, Jean; Chair, SY; Lee, Vivian; Choi, KC; Lo, Raymond

Article 6

C-reactive protein and ageing

Clinical and Experimental Pharmacology and Physiology, v. 44, December 2017, article number 12758, p. 9-14
Tang, Ying; Fung, Erik; Xu, Anping; Lan, Hui-Yao

Deletion of angiotensin-converting enzyme-2 promotes hypertensive nephropathy by targeting smad7 for ubiquitin degradation

Hypertension, v. 70, (4), October 2017, p. 822-830
Liu, Zhen; Huang, Xiao-Ru; Chen, Hai-Yong; Fung, Erik; Liu, Jian; Lan, Hui-Yao

Frailty, co-morbidities and survival in heart failure patients with mid-range ejection fraction

European Heart Journal, v. 38, (Supplement 1), August 2017, p. 111-111
Moliner, P.; Gastelurrutia, P.; Lupon, J.; Yang, X.; De Antonio, M.; Domingo, M.; Altimir, S.; Gonzalez, B.; Rodriguez, M.; Rivas, C.; Fung, Erik; Zamora, E.; Santesmases, J.; Woo, J.; Bayes-Genis, A.

Risks of mortality and hospitalisation in patients with frailty and chronic heart failure: systematic review and meta-analysis

European Heart Journal, v. 38, (Supplement 1), August 2017, article number P4379, p. 906-907
Yang, X.; Lupon, J.; Gastelurrutia, P.; Newton, P.; Bueno, H.; Bayes-Genis, A.; Woo, J.; Fung, Erik

The incidence, risk factors and in-hospital mortality of acute kidney injury in patients after abdominal aortic aneurysm repair surgery

BMC Nephrology, v. 18, (1), May 2017, article number 184
Tang, Ying; Chen, Junzhe; Huang, Kai; Luo, Dan; Liang, Peifen; Feng, Min; Chai, Wenxin; Fung, Erik; Lan, Hui Yao; Xu, Anping

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

Scientific Reports, v. 7, (1), December 2017, article number 1481
Yang, Chen; Huang, Xiao-Ru; Fung, Erik; Liu, Hua-Feng; Lan, Hui-Yao

Article 2

Fulminant eosinophilic myocarditis following ICD implantation in a patient with undisclosed nickel allergy

International Journal of Cardiology, v. 203, January 2016, p. 1018-1019
Fung, Erik; Fong, Michael W.; Correa, Adrian J.; Yoon, Andrew J.; Grazette, Luanda P.

Prevalence of LVAD Items Available for Sale on eBay in the US and Other Countries

Journal of Cardiac Failure, v. 22, (8), August 2016, article number 345, p. S120
Fung, Erik; Grazette, Luanda; Saxon, Leslie; Bowdish, Michael; Yoon, Andrew J.

Article 3

Electrocardiographic patch devices and contemporary wireless cardiac monitoring

Frontiers in Physiology, v. 6, (MAY), May 2015, article number 149
Fung, Erik; Järvelin, Marjo-Riitta; Doshi, Rahul N.; Shinbane, Jerold S.; Carlson, Steven K.; Grazette, Luanda P.; Chang, Philip M.; Sangha, Rajbir S.; Huikuri, Heikki V.; Peters, Nicholas S.

Evolution from electrophysiologic to hemodynamic monitoring: The story of left atrial and pulmonary artery pressure monitors

Frontiers in Physiology, v. 6, (OCT), October 2015, article number 271
Mooney, Deirdre M.; Fung, Erik; Doshi, Rahul N.; Shavelle, David M.

Meta-analysis of randomized controlled trials of genotype-guided vs standard dosing of warfarin

Chest, v. 148, (3), September 2015, p. 701-710
Dahal, Khagendra; Sharma, Sharan P.; Fung, Erik; Lee, Juyong; Moore, Jason H.; Unterborn, John N.; Williams, Scott M.

Article 1

Infant locomotive development and its association with adult blood pressure

European Journal of Pediatrics, v. 173, (10), September 2014, p. 1309-1317
Pillas, Demetris; Fung, Erik; Jarvelin, Marjo-Riitta

Article 2

Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin

Seminars in Thrombosis and Hemostasis, v. 38, (8), November 2012, p. 893-904
Fung, Erik; Patsopoulos, Nikolaos A.; Belknap, Steven M.; O'Rourke, Daniel J.; Robb, John F.; Anderson, Jeffrey L.; Shworak, Nicholas W.; Moore, Jason H.

Macrophages in collateral arteriogenesis

Frontiers in Physiology, v. 3 SEP, September 2012, article number 353
Fung, Erik; Helisch, Armin

Article 1

Multiplexed immunophenotyping of human antigen-presenting cells in whole blood by polychromatic flow cytometry

Nature Protocols, v. 5, (6), February 2010, p. 357-370
Fung, Erik; Esposito, Laura; Todd, John A.; Wicker, Linda S.

Article 4

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

Genes and Immunity, v. 10, (2), March 2009, p. 188-191
Fung, Erik; Smyth, D.J.; Howson, J.M.M.; Cooper, J.D.; Walker, N.M.; Stevens, H.; Wicker, L.S.; Todd, J.A.

Cell-specific CD25 Expression is Determined by Type 1 Diabetes Associated IL2RA Haplotypes

Clinical Immunology, v. 131, (Supplement), April 2009, p. S94
Dendrou, Calliope; Plagnol, Vincent; Fung, Erik; Downes, Kate; Cooper, Jason; Nutland, Sarah; Coleman, Gillian; Himsworth, Matthew; Hardy, Matthew; Burren, Oliver; Healy, Barry; Walker, Neil; Koch, Kerstin; Ouwehand, Willem; Wareham, Nicholas; Todd, John; Wicker, Linda

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

Nature Genetics, v. 41, (9), August 2009, p. 1011-1015
Dendrou, Calliope A; Plagnol, Vincent; Fung, Erik; Yang, Jennie H M; Downes, Kate; Cooper, Jason D; Nutland, Sarah; Coleman, Gillian; Himsworth, Matthew; Hardy, Matthew; Burren, Oliver; Healy, Barry; Walker, Neil M; Koch, Kerstin; Ouwehand, Willem H; Bradley, John R; Wareham, Nicholas J; Todd, John A; Wicker, Linda S

Fluorescence Intensity Normalisation: Correcting for Time Effects in Large-Scale Flow Cytometric Analysis

Advances in Bioinformatics, v. 2009, (1), November 2009, article number 476106
Dendrou, Calliope A.; Fung, Erik; Esposito, Laura; Todd, John A.; Wicker, Linda S.; Plagnol, Vincent

Article 3

Delta-like 4 induces Notch signaling in macrophages: Implications for inflammation

Circulation, v. 115, (23), June 2007, p. 2948-2956
Fung, Erik; Tang, Sai-Man Timothy; Canner, James P.; Morishige, Kunio; Arboleda-Velasquez, Joseph F.; Cardoso, Angelo A.; Carlesso, Nadia; Aster, Jon C.; Aikawa, Masanori

Monocyte biomarkers in autoimmune type 1 diabetes

Acta Diabetologica, v. 44, November 2007, p. S17
Fung, Erik; Plagnol, Vincent; Healy, Barry; Burren, Oliver; Todd, John A.; Wicker, Linda S.

Monocyte immunophenotypes in type 1 diabetes

Clinical Immunology, v. 123, (S), 2007, p. S19-S20
Fung, Erik; Todd, John A.; Wicker, Linda S.

Article 3

CADASIL mutations impair Notch3 glycosylation by Fringe

Human Molecular Genetics, v. 14, (12), June 2005, p. 1631-1639
Arboleda-Velasquez, Joseph F.; Rampal, Raajit; Fung, Erik; Darland, Diane C.; Liu, Min; Martinez, Maria C.; Donahue, Christine P.; Navarro-Gonzalez, Manuel F.; Libby, Peter; D'Amore, Patricia A.; Aikawa, Masanori; Haltiwanger, Robert S.; Kosik, Kenneth S.

Interleukin-1β is a novel target of Notch signaling in macrophages

Circulation, v. 112, (17), October 2005, p. U56
Morishige, Kunio; Tang, S.M. Timothy; Fung, Erik; Aster, Jon C.; Aikawa, Masanori

The potential use of type-5 phosphodiesterase inhibitors in coronary artery bypass graft surgery

Chest, v. 128, (4), October 2005, p. 3065-3073
Fung, Erik; Fiscus, Ronald R.; Yim, Anthony P. C.; Angelini, Gianni D.; Arifi, Ahmed A.

Article 1

Induction of the Notch pathway in activated human macrophages

Circulation, v. 110, (17), October 2004, p. 274
Fung, Erik; Arboleda-Velasquez, Joseph; Deguchi, Jun-o; Libby, Peter; Kosik, Kenneth S.; Aikawa, Masanori

Article 1

Adrenomedullin induces direct (endothelium-independent) vasorelaxations and cyclic adenosine monophosphate elevations that are synergistically enhanced by brain natriuretic peptide in isolated rings of rat thoracic aorta

Journal of Cardiovascular Pharmacology, v. 41, (6), June 2003, p. 849-855
Fung, Erik; Fiscus, Ronald R.

Article 1

Brain Natriuretic Peptide (BNP)-Induced Cyclic GMP Elevations Synergistically Enhance the Vasodilatory and Cyclic AMP Responses to Adrenomedullin in Rat Aortic Rings

Journal of Cardiac Surgery, v. 17, (6), November 2002, article number 101423, p. 565-566
Fung, Erik; Fiscus, Ronald R

Article 1

Synergistic potentiation of adrenomedullin-induced vasorelaxations and cAMP elevations by brain natriuretic peptide (BNP) in endothelium-denuded rat thoracic aorta

Cell Biology International, v. 25, 2001, p. 1052
Fung, Erik; Fiscus, Ronald R.

2019 13

Analysis of survival associated with pulmonary arterial hypertension in patients with systemic lupus erythematosus

Annals of the Rheumatic Diseases, v. 78, (Supplement 2), June 2019, article number THU0264, p. 410
Ho, Chi; Fung, Erik; Tam, Lai-Shan
Article

Association analysis of N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) and growth differentiation factor 15 (GDF-15) in cardiac and non-cardiac frailty

European Journal of Heart Failure, v. 21, (S1), May 2019, p. 428-429
Li, Qi; Lui , Leong Ting; Yang, Xiaobo; Liu, Simin; Cheng, King Fai; Lupón, Josep; Bayés-Genís, Antoni; Sahota, Daljit; Woo, Jean; Fung, Erik
Article

Cardiomems^TM in VAD patients

Heart Asia, v. 11, (Supplement 1), August 2019, article number 26, p. A2
Fung, Erik
Article

Early Unplanned Readmissions After Admission to Hospital With Heart Failure

American Journal of Cardiology, v. 124, (5), September 2019, p. 736-745
Kwok, Chun Shing; Seferovic, Petar M; Van Spall, Harriette GC; Helliwell, Toby; Clarson, L.; Lawson, Claire; Kontopantelis, Evangelos; Patwala, Ashish; Duckett, S.; Fung, Erik; Mallen, Christian D; Mamas, Mamas A
Article

Fabry disease in east asia

Heart Asia, v. 11, (Supplement 1), August 2019, article number 31
Lee, Alex PW; Kam, Kevin KH; Fung, Erik; Chow, Josie; Fan, Yiting; Teekakirikul, Polakit; Wong, Katak; Chan, Joseph YS; Chan, David; Sheng, Bun
Article

Frailty, Diastolic Dysfunction, And Latent Heart Failure In The Community-living Elderly In Hong Kong: Cross-sectional Findings From The Ufo Study

Journal of the American College of Cardiology, v. 73, (9), March 2019, p. 1873
Fung, Erik; Yang, Xiaobo; Lui, Leong Ting; Li, Qi; Cheng, King Fai; Sahota, Daljit; Fan, Yiting; Lee, Jenny S.W.; Lee, Alex P.W.; Hui, Elsie; Woo, Jean
Article

Hypertrophic cardiomyopathy: An overview of genetics and management

Biomolecules, v. 9, (12), December 2019, article number 878
Teekakirikul, Polakit; Zhu, Wenjuan; Huang, Helen C.; Fung, Erik
Article

Multifaceted Functions of Epithelial Na+ Channel in Modulating Blood Pressure

Hypertension, v. 73, (2), February 2019, p. 273-281
Li, Qi; Fung, Erik
Article

Optimising heart failure care by multi-disciplinary heart failure clinic (MHFC)

Heart Asia, v. 11, (Supplement 1), August 2019, article number 5, p. A2
Kam, Kevin KH; Yu, Ada; Fung, Erik; Lee, Alex PW
Article

Peak Oxygen Uptake, Oxygen Uptake Efficiency Slope, And 6-minute Walk Distance Can Predict Long-term Survival In Community-based Nonfrail Older Adults

Canadian Journal of Cardiology, v. 35, (10), October 2019, p. S60-S61
Fung, Erik; Woo, J.; Leung, J.; Yau, F.
Article

Sarcopenia and reduced physical fitness are associated with cardiac dysfunction in community-living older adults

European Journal of Heart Failure, v. 21, (S1), May 2019, p. 535
Yang, Xiaobo; Lui, Leong Ting; Qi, Li; Cheng, King Fai; Liu, Simin; Yau, Forrest; Fan, Yiting; Lee, Alex P.W.; Woo, Jean; Fung, Erik
Article

Use of direct oral anticoagulant in atrial fibrillation with gastrointestinal bleeding: Balancing gastrointestinal safety and cardiovascular risks

Journal of Gastroenterology and Hepatology (Australia), v. 34, (6), June 2019, p. 959-960
Sung, Joseph JY; Fung, Erik
Article

Utility of the FRAIL Questionnaire in Detecting Heart Failure with Preserved Ejection Fraction

Journal of Nutrition, Health and Aging, v. 23, (4), April 2019, p. 373-377
Woo, Jean; Yang, X.; Lui, L. Tin; Li, Q.; Cheng, K. Fai; Fan, Y.; Yau, F.; Lee, A.P.W.; Lee, J.S.W.; Fung, Erik
Article

2018 9

#Frailty: A snapshot Twitter report on frailty knowledge translation

Australasian Journal on Ageing, v. 37, (4), December 2018, p. 309-312
Jha, Sunita R; McDonagh, Julee; Prichard, Ros; Newton, Phillip J; Hickman, Louise D; Fung, Erik; Macdonald, Peter S; Ferguson, Caleb
Article

Anticoagulation for mechanical circulatory support

Heart Asia, v. 10, (Supplement 1), 2018-11, article number 23, p. A6
Fung, Erik
Article

Association between oxygen uptake efficiency slope (OUES), an effort-independent measure of cardiorespiratory fitness (VO2max), and robust/pre-frail status in an elderly Chinese population

European Journal of Heart Failure, v. 20, (S1), May 2018, p. 528-529
Fung, Erik; Lui, Leong Ting; Yau, Forrest; Leung, Jason; Woo, Jean
Article

Comorbidities, fragility, and quality of life in heart failure patients with midrange ejection fraction

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, v. 2, (2), June 2018, article number 176
Gastelurrutia, Paloma; Lupon, Josep; Moliner, Pedro; Yang, Xiaobo; Cediel, German; de Antonio, Marta; Domingo, Mar; Altimir, Salvador; González, Beatriz; Rodríguez, Margarita; Rivas, Carmen; Díaz, Violeta; Fung, Erik; Zamora, Elisabet; Santesmases, Javier; Núñez, Julio; Woo, Jean; Bayes-Genis, Antoni
Article

Heart failure and frailty in the community-living elderly population: What the UFO study will tell us

Frontiers in Physiology, v. 9, (APR), April 2018, article number 347
Fung, Erik; Hui, Elsie; Yang, Xiaobo; Lui, Leong T.; Cheng, King F.; Li, Qi; Fan, Yiting; Sahota, Daljit S.; Ma, Bosco H.M.; Lee, Jenny S.W.; Lee, Alex P.W.; Woo, Jean
Article

Impact of frailty on mortality and hospitalization in chronic heart failure: A systematic review and meta-analysis

Journal of the American Heart Association, v. 7, (23), December 2018, article number e008251
Yang, Xiaobo; Lupón, Josep; Vidán, Maria T.; Ferguson, Caleb; Gastelurrutia, Paloma; Newton, Phillip J.; Macdonald, Peter S.; Bueno, Héctor; Bayés-Genís, Antoni; Woo, Jean; Fung, Erik
Article

Letter by Fung et al Regarding Article, “Frailty and Clinical Outcomes in Heart Failure: A Systematic Review and Meta-analysis”

Journal of the American Medical Directors Association, v. 19, (12), December 2018, p. 1143-1146
Fung, Erik; Yang, Xiaobo; Newton, Phillip J.; Ferguson, Caleb; Gastelurrutia, Paloma; Lupón, Josep; Bayés-Genís, Antoni; Jha, Sunita; Macdonald, Peter S.
Article

Performance Of Cardiopulmonary Exercise Capacity And Physical Fitness Indicators In Differentiating Pre-frail And Robust Elderly

Canadian Journal of Cardiology, v. 34, (10), October 2018, p. S6-S7
Fung, Erik; Lui, L.; Leung, J.; Woo, J.
Article

Supportive cardiology: an innovative practice model to integrate palliative care into the management of advanced heart failure

Heart Asia, v. 10, (Supplementary 1), November 2018, article number 22, p. A7
Yu, Doris; Li, Polly; Fung, Erik; Yuen, Jacqueline; Woo, Jean; Chair, SY; Lee, Vivian; Choi, KC; Lo, Raymond
Article

2017 6

C-reactive protein and ageing

Clinical and Experimental Pharmacology and Physiology, v. 44, December 2017, article number 12758, p. 9-14
Tang, Ying; Fung, Erik; Xu, Anping; Lan, Hui-Yao
Article

Deletion of angiotensin-converting enzyme-2 promotes hypertensive nephropathy by targeting smad7 for ubiquitin degradation

Hypertension, v. 70, (4), October 2017, p. 822-830
Liu, Zhen; Huang, Xiao-Ru; Chen, Hai-Yong; Fung, Erik; Liu, Jian; Lan, Hui-Yao
Article

Frailty, co-morbidities and survival in heart failure patients with mid-range ejection fraction

European Heart Journal, v. 38, (Supplement 1), August 2017, p. 111-111
Moliner, P.; Gastelurrutia, P.; Lupon, J.; Yang, X.; De Antonio, M.; Domingo, M.; Altimir, S.; Gonzalez, B.; Rodriguez, M.; Rivas, C.; Fung, Erik; Zamora, E.; Santesmases, J.; Woo, J.; Bayes-Genis, A.
Article

Risks of mortality and hospitalisation in patients with frailty and chronic heart failure: systematic review and meta-analysis

European Heart Journal, v. 38, (Supplement 1), August 2017, article number P4379, p. 906-907
Yang, X.; Lupon, J.; Gastelurrutia, P.; Newton, P.; Bueno, H.; Bayes-Genis, A.; Woo, J.; Fung, Erik
Article

The incidence, risk factors and in-hospital mortality of acute kidney injury in patients after abdominal aortic aneurysm repair surgery

BMC Nephrology, v. 18, (1), May 2017, article number 184
Tang, Ying; Chen, Junzhe; Huang, Kai; Luo, Dan; Liang, Peifen; Feng, Min; Chai, Wenxin; Fung, Erik; Lan, Hui Yao; Xu, Anping
Article

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

Scientific Reports, v. 7, (1), December 2017, article number 1481
Yang, Chen; Huang, Xiao-Ru; Fung, Erik; Liu, Hua-Feng; Lan, Hui-Yao
Article

2016 2

Fulminant eosinophilic myocarditis following ICD implantation in a patient with undisclosed nickel allergy

International Journal of Cardiology, v. 203, January 2016, p. 1018-1019
Fung, Erik; Fong, Michael W.; Correa, Adrian J.; Yoon, Andrew J.; Grazette, Luanda P.
Article

Prevalence of LVAD Items Available for Sale on eBay in the US and Other Countries

Journal of Cardiac Failure, v. 22, (8), August 2016, article number 345, p. S120
Fung, Erik; Grazette, Luanda; Saxon, Leslie; Bowdish, Michael; Yoon, Andrew J.
Article

2015 3

Electrocardiographic patch devices and contemporary wireless cardiac monitoring

Frontiers in Physiology, v. 6, (MAY), May 2015, article number 149
Fung, Erik; Järvelin, Marjo-Riitta; Doshi, Rahul N.; Shinbane, Jerold S.; Carlson, Steven K.; Grazette, Luanda P.; Chang, Philip M.; Sangha, Rajbir S.; Huikuri, Heikki V.; Peters, Nicholas S.
Article

Evolution from electrophysiologic to hemodynamic monitoring: The story of left atrial and pulmonary artery pressure monitors

Frontiers in Physiology, v. 6, (OCT), October 2015, article number 271
Mooney, Deirdre M.; Fung, Erik; Doshi, Rahul N.; Shavelle, David M.
Article

Meta-analysis of randomized controlled trials of genotype-guided vs standard dosing of warfarin

Chest, v. 148, (3), September 2015, p. 701-710
Dahal, Khagendra; Sharma, Sharan P.; Fung, Erik; Lee, Juyong; Moore, Jason H.; Unterborn, John N.; Williams, Scott M.
Article

2014 1

Infant locomotive development and its association with adult blood pressure

European Journal of Pediatrics, v. 173, (10), September 2014, p. 1309-1317
Pillas, Demetris; Fung, Erik; Jarvelin, Marjo-Riitta
Article

2012 2

Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin

Seminars in Thrombosis and Hemostasis, v. 38, (8), November 2012, p. 893-904
Fung, Erik; Patsopoulos, Nikolaos A.; Belknap, Steven M.; O'Rourke, Daniel J.; Robb, John F.; Anderson, Jeffrey L.; Shworak, Nicholas W.; Moore, Jason H.
Article

Macrophages in collateral arteriogenesis

Frontiers in Physiology, v. 3 SEP, September 2012, article number 353
Fung, Erik; Helisch, Armin
Article

2010 1

Multiplexed immunophenotyping of human antigen-presenting cells in whole blood by polychromatic flow cytometry

Nature Protocols, v. 5, (6), February 2010, p. 357-370
Fung, Erik; Esposito, Laura; Todd, John A.; Wicker, Linda S.
Article

2009 4

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

Genes and Immunity, v. 10, (2), March 2009, p. 188-191
Fung, Erik; Smyth, D.J.; Howson, J.M.M.; Cooper, J.D.; Walker, N.M.; Stevens, H.; Wicker, L.S.; Todd, J.A.
Article

Cell-specific CD25 Expression is Determined by Type 1 Diabetes Associated IL2RA Haplotypes

Clinical Immunology, v. 131, (Supplement), April 2009, p. S94
Dendrou, Calliope; Plagnol, Vincent; Fung, Erik; Downes, Kate; Cooper, Jason; Nutland, Sarah; Coleman, Gillian; Himsworth, Matthew; Hardy, Matthew; Burren, Oliver; Healy, Barry; Walker, Neil; Koch, Kerstin; Ouwehand, Willem; Wareham, Nicholas; Todd, John; Wicker, Linda
Article

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

Nature Genetics, v. 41, (9), August 2009, p. 1011-1015
Dendrou, Calliope A; Plagnol, Vincent; Fung, Erik; Yang, Jennie H M; Downes, Kate; Cooper, Jason D; Nutland, Sarah; Coleman, Gillian; Himsworth, Matthew; Hardy, Matthew; Burren, Oliver; Healy, Barry; Walker, Neil M; Koch, Kerstin; Ouwehand, Willem H; Bradley, John R; Wareham, Nicholas J; Todd, John A; Wicker, Linda S
Article

Fluorescence Intensity Normalisation: Correcting for Time Effects in Large-Scale Flow Cytometric Analysis

Advances in Bioinformatics, v. 2009, (1), November 2009, article number 476106
Dendrou, Calliope A.; Fung, Erik; Esposito, Laura; Todd, John A.; Wicker, Linda S.; Plagnol, Vincent
Article

2007 3

Delta-like 4 induces Notch signaling in macrophages: Implications for inflammation

Circulation, v. 115, (23), June 2007, p. 2948-2956
Fung, Erik; Tang, Sai-Man Timothy; Canner, James P.; Morishige, Kunio; Arboleda-Velasquez, Joseph F.; Cardoso, Angelo A.; Carlesso, Nadia; Aster, Jon C.; Aikawa, Masanori
Article

Monocyte biomarkers in autoimmune type 1 diabetes

Acta Diabetologica, v. 44, November 2007, p. S17
Fung, Erik; Plagnol, Vincent; Healy, Barry; Burren, Oliver; Todd, John A.; Wicker, Linda S.
Article

Monocyte immunophenotypes in type 1 diabetes

Clinical Immunology, v. 123, (S), 2007, p. S19-S20
Fung, Erik; Todd, John A.; Wicker, Linda S.
Article

2005 3

CADASIL mutations impair Notch3 glycosylation by Fringe

Human Molecular Genetics, v. 14, (12), June 2005, p. 1631-1639
Arboleda-Velasquez, Joseph F.; Rampal, Raajit; Fung, Erik; Darland, Diane C.; Liu, Min; Martinez, Maria C.; Donahue, Christine P.; Navarro-Gonzalez, Manuel F.; Libby, Peter; D'Amore, Patricia A.; Aikawa, Masanori; Haltiwanger, Robert S.; Kosik, Kenneth S.
Article

Interleukin-1β is a novel target of Notch signaling in macrophages

Circulation, v. 112, (17), October 2005, p. U56
Morishige, Kunio; Tang, S.M. Timothy; Fung, Erik; Aster, Jon C.; Aikawa, Masanori
Article

The potential use of type-5 phosphodiesterase inhibitors in coronary artery bypass graft surgery

Chest, v. 128, (4), October 2005, p. 3065-3073
Fung, Erik; Fiscus, Ronald R.; Yim, Anthony P. C.; Angelini, Gianni D.; Arifi, Ahmed A.
Article

2004 1

Induction of the Notch pathway in activated human macrophages

Circulation, v. 110, (17), October 2004, p. 274
Fung, Erik; Arboleda-Velasquez, Joseph; Deguchi, Jun-o; Libby, Peter; Kosik, Kenneth S.; Aikawa, Masanori
Article

2003 1

Adrenomedullin induces direct (endothelium-independent) vasorelaxations and cyclic adenosine monophosphate elevations that are synergistically enhanced by brain natriuretic peptide in isolated rings of rat thoracic aorta

Journal of Cardiovascular Pharmacology, v. 41, (6), June 2003, p. 849-855
Fung, Erik; Fiscus, Ronald R.
Article

2002 1

Brain Natriuretic Peptide (BNP)-Induced Cyclic GMP Elevations Synergistically Enhance the Vasodilatory and Cyclic AMP Responses to Adrenomedullin in Rat Aortic Rings

Journal of Cardiac Surgery, v. 17, (6), November 2002, article number 101423, p. 565-566
Fung, Erik; Fiscus, Ronald R
Article

2001 1

Synergistic potentiation of adrenomedullin-induced vasorelaxations and cAMP elevations by brain natriuretic peptide (BNP) in endothelium-denuded rat thoracic aorta

Cell Biology International, v. 25, 2001, p. 1052
Fung, Erik; Fiscus, Ronald R.
Article

Research Interest

Publications

2025 8

2024 6

2023 5

2022 7

2021 9

2020 11

2019 13

2018 9

2017 6

2016 2

2015 3

2014 1

2012 2

2010 1

2009 4

2007 3

2005 3

2004 1

2003 1

2002 1

2001 1

Article 5

Conference paper 3

Article 6

Article 5

Article 6

Conference paper 1

Article 9

Article 11

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