Crystal structure of a tetrameric RNA G-quadruplex formed by hexanucleotide repeat expansions of C9orf72 in ALS/FTD

Discovery of a novel marine bacterial AIEgen that lights up specific G-quadruplexes

PRDX1 Interfering Peptide Disrupts Amino Acids 70–90 of PRDX1 to Inhibit the TLR4/NF-κB Signaling Pathway and Attenuate Neuroinflammation and Ischemic Brain Injury

TAT-W61 peptide attenuates neuronal injury through blocking the binding of S100b to the V-domain of Rage during ischemic stroke

The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex

An Essential Noc3p Dimerization Cycle Mediates ORC Double-Hexamer Formation in Replication Licensing

Cryo-EM structure of human hexameric MCM2-7 complex

Selective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models

The parallel tetrameric DNA G-quadruplex formed by the two-repeat C9orf72 GGGGCC sequence in solution: Dedicated to Professor Chaohui Ye on the occasion of his 80th birthday

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS-and FTD-related GGGGCC sequence

Crystal structure of parallel G-quadruplex formed by the two-repeat ALS and FTD related GGGGCC sequence

An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication

Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K⁺ solution

G-quadruplex structures formed by human telomeric DNA and C9orf72 hexanucleotide repeats

The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA

Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence

ALS和FTD相关的双重重复GGGGCC序列形成的平行和反平行G-四链体的表征

K+溶液中8-溴代鸟苷取代的人端粒序列形成的的椅式G-四链体拓扑结构及其变体的NMR溶液结构

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构

¹H, ¹⁵N and ¹³C chemical shift assignments of the homeodomain of Hoxc9 in complex with the cell cycle regulator Geminin

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction

Quadruplex Nucleic Acid Structure Determination by Solution NMR

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad

Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex

Butenolide inhibits marine fouling by altering the primary metabolism of three target organisms

Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode

Structural basis for homeodomain recognition by the cell-cycle regulator Geminin

Structural insights into the Cdt1-mediated MCM2-7 chromatin loading

Crowding effect on calmodulin bakcbone dynamics

基于Cdt1调节的MCM2-7复合物染色质装配的结构机制

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6

Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy

人Mcm6蛋白Cdt1相结合结构域的溶液结构

SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20

Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence

Article

ALS和FTD相关的双重重复GGGGCC序列形成的平行和反平行G-四链体的表征

Conference paper

K+溶液中8-溴代鸟苷取代的人端粒序列形成的的椅式G-四链体拓扑结构及其变体的NMR溶液结构

Conference paper

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Conference paper

与ALS/FTD相关联的C9orf72六核苷酸重复扩增所形成G-四链体DNA的拓扑结构

Conference paper

¹H, ¹⁵N and ¹³C chemical shift assignments of the homeodomain of Hoxc9 in complex with the cell cycle regulator Geminin

Article

Development of stapled helical peptides to perturb the Cdt1-Mcm6 interaction

Article

Quadruplex Nucleic Acid Structure Determination by Solution NMR

Article

Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD

Article

Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad

Conference paper

Molecular basis of the general base catalysis of an α/β- hydrolase catalytic triad

Article

Molecular Basis of the General Base Catalysis of an α/β-Hydrolase Catalytic Triad

Conference paper

Structure-functional Study of Proteins that Regulate Cell Proliferation and Differentiation

Conference paper

The Chair-type Structure of the Intramolecular Human Telomeric G-quadruplex

Conference paper

Butenolide inhibits marine fouling by altering the primary metabolism of three target organisms

Article

Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode

Article

Structural basis for homeodomain recognition by the cell-cycle regulator Geminin

Article

Structural insights into the Cdt1-mediated MCM2-7 chromatin loading

Article

Crowding effect on calmodulin bakcbone dynamics

Conference paper

基于Cdt1调节的MCM2-7复合物染色质装配的结构机制

Conference paper

¹H, ¹⁵N and ¹³C chemical shift assignments of the SH2 domain of human tensin2 (TENC1)

Article

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Conference paper

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Conference paper

¹H, ¹⁵N and ¹³C chemical shift assignments of the Cdt1 binding domain of human Mcm6

Article

Characterization and structure determination of the cdt1 binding domain of human minichromosome maintenance (Mcm) 6

Article

Studying base pair open-close kinetics of tRNA^Leu by TROSY-based proton exchange NMR spectroscopy

Article

人Mcm6蛋白Cdt1相结合结构域的溶液结构

Conference paper

SET8 recognizes the sequence RHRK²⁰VLRDN within the N terminus of histone H4 and mono-methylates lysine 20

Article