Faculty Profiles - YANG Can | The Hong Kong University of Science and Technology

2024 5

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

Nature Communications, v. 15, (1), March 2024, article number 2188, p. 1-27
The Tabula Microcebus Consortium; Liu, Shixuan; Jing, Qiuyu; Ming, Jingsi; Wang, Gefei; Wu, Angela Ruohao; Yang, Can; Yang, Jinxurong; Zhao, Jia; Krasnow, Mark A.; Ferrell, James E.
Article

Association Between Sleep Efficiency Variability and Cognition Among Older Adults: Cross-Sectional Accelerometer Study

JMIR Aging, v. 7, April 2024, article number e54353, p. 1-7
Sakal, Collin; Li, Tingyou; Li, Juan; Yang, Can; Li, Xinyue
Article

Benchmarking Mendelian randomization methods for causal inference using genome-wide association study summary statistics

American Journal of Human Genetics, v. 111, (8), August 2024, p. 1717-1735
Hu, Xianghong; Cai, Mingxuan; Xiao, Jiashun; Wan, Xiaomeng; Wang, Zhiwei; Zhao, Hongyu; Yang, Can
Article

Computational methods for alignment and integration of spatially resolved transcriptomics data

Computational and Structural Biotechnology Journal, v. 23, December 2024, p. 1094-1105
Liu, Yuyao; Yang, Can
Article

MFAI: A Scalable Bayesian Matrix Factorization Approach to Leveraging Auxiliary Information

Journal of Computational and Graphical Statistics, March 2024
Wang, Zhiwei; Zhang, Fa; Zheng, Cong; Hu, Xianghong; Cai, Mingxuan; Yang, Can
Article

2023 8

BOLT-SSI: A Statistical Approach to Screening Interaction Effects for Ultra-High Dimensional Data

Statistica Sinica, v. 33, (4), October 2023, p. 2327-2358
Zhou, Min; Dai, Mingwei; Yao, Yuan; Liu, Jin; Yang, Can; Peng, Heng
Article

Construction of a 3D whole organism spatial atlas by joint modelling of multiple slices with deep neural networks

Nature Machine Intelligence, v. 5, (11), November 2023, p. 1200-1213
Wang, Gefei; Zhao, Jia; Yan, Yan; Wang, Yang; Wu, Angela Ruohao; Yang, Can
Article

Integrating spatial and single-cell transcriptomics data using deep generative models with SpatialScope

Nature Communications, v. 14, (1), November 2023, article number 7848
Wan, Xiaomeng; Xiao, Jiashun; Tam, Sindy Sing Ting; Cai, Mingxuan; Sugimura, Ryohichi; Wang, Yang; Wan, Xiang; Lin, Zhixiang; Wu, Angela Ruohao; Yang, Can
Article

Organoid-based single-cell spatiotemporal gene expression landscape of human embryonic development and hematopoiesis

Signal Transduction and Targeted Therapy, v. 8, (1), June 2023, article number 230
Chao, Yiming; Xiang, Yang; Xiao, Jiashun; Zheng, Weizhong; Ebrahimkhani, Mo R.; Yang, Can; Wu, Angela Ruohao; Liu, Pentao; Huang, Yuanhua; Sugimura, Ryohichi
Article

PALM: a powerful and adaptive latent model for prioritizing risk variants with functional annotations

Bioinformatics, v. 39, (2), February 2023, article number btad068
Yu, Xinyi; Xiao, Jiashun; Cai, Mingxuan; Jiao, Yuling; Wan, Xiang; Liu, Jin; Yang, Can
Article

Reconstructing Close Human Interactions from Multiple Views

ACM Transactions on Graphics, v. 42, (6), December 2023, article number 273, p. 1-14
Shuai, Qing; Yu, Zhiyuan; Zhou, Zhize; Fan, Lixin; Yang, Haijun; Yang, Can; Zhou, Xiaowei
Article

stVAE deconvolves cell-type composition in large-scale cellular resolution spatial transcriptomics

Bioinformatics (Oxford, England), v. 39, (10), October 2023, article number btad642
Li, Chen; Chan, Ting-Fung; Yang, Can; Lin, Zhixiang
Article

XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias

Nature Communications, v. 14, (1), 2023, article number 6870
Cai, Mingxuan; Wang, Zhiwei; Xiao, Jiashun; Hu, Xianghong; Chen, Gang; Yang, Can
Article

2022 5

FIRM: Flexible integration of single-cell RNA-sequencing data for large-scale multi-tissue cell atlas datasets

Briefings in Bioinformatics, v. 23, (5), September 2022, article number bbac167
The Tabula Microcebus Consortium; Ming, Jingsi; Lin, Zhixiang; Zhao, Jia; Wan, Xiang; Yang, Can; Wu, Angela Ruohao
Article

Leveraging the local genetic structure for trans-ancestry association mapping

American Journal of Human Genetics, v. 109, (7), July 2022, p. 1317-1337
Xiao, Jiashun; Cai, Mingxuan; Yu, Xinyi; Hu, Xianghong; Chen, Gang; Wan, Xiang; Yang, Can
Article

Mendelian Randomization for Causal Inference Accounting for Pleiotropy and Sample Structure Using Genome-Wide Summary Statistics

Proceedings of the National Academy of Sciences of the United States of America, v. 119, (28), July 2022, article number e2106858119
Hu, Xianghong; Zhao, Jia; Lin, Zhixiang; Wang, Yang; Peng, Heng; Zhao, Hongyu; Wan, Xiang; Yang, Can
Article

scPI: A Scalable Framework for Probabilistic Inference in Single-Cell RNA-Sequencing Data Analysis

Statistics in Biosciences, 31 January 2022
Ming, Jingsi; Zhao, Jia; Yang, Can
Article

XPXP: Improving polygenic prediction by cross-population and cross-phenotype analysis.

Bioinformatics, v. 38, (7), April 2022, p. 1947-1955
Xiao, Jiashun; Cai, Mingxuan; Hu, Xianghong; Wan, Xiang; Chen, Gang; Yang, Can
Article

2021 6

A unified framework for cross-population trait prediction by leveraging the genetic correlation of polygenic traits

American Journal of Human Genetics, v. 108, (4), April 2021, p. 632-655
Cai, Mingxuan; Xiao, Jiashun; Zhang, Shunkang; Wan, Xiang; Zhao, Hongyu; Chen, Gang; Yang, Can
Article

A Unified Primal Dual Active Set Algorithm for Nonconvex Sparse Recovery

Statistical Science, v. 36, (2), May 2021, p. 215-238
Huang, Jian; Jiao, Yuling; Jin, Bangti; Liu, Jin; Lu, Xiliang; Yang, Can
Article

Accurate genetic and environmental covariance estimation with composite likelihood in genome-wide association studies

PLoS Genetics, v. 17, (1), January 2021, article number e1009293
Gao, Boran; Yang, Can; Liu, Jin; Zhou, Xiang
Article

REMI: regression with marginal information and its application in genome-wide association studies

Statistica Sinica, v. 31, (4), October 2021, p. 1985-2004
Huang, Jian; Jiao, Yuling; Liu, Jin; Yang, Can
Article

Using Collaborative Mixed Models to Account for Imputation Uncertainty in Transcriptome-Wide Association Studies

Epistasis: Methods and Protocols / Edited by Ka-Chun Wong. New York : Humana Press Inc, 2021, p. 93-103, Book series: Methods in Molecular Biology, v.2212
Shi, Xingjie; Yang, Can; Liu, Jin
Book chapter

Deep Generative Learning via Schrödinger Bridge

Proceedings of the 38th International Conference on Machine Learning, v. 139, July 2021, p. 10794-10804
Wang, Gefei; Jiao, Yuling; Xu, Qian; Wang, Yang; Yang, Can
Conference paper

2020 10

A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies

Nucleic Acids Research, v. 48, (19), November 2020
Shi, Xingjie; Chai, Xiaoran; Yang, Yi; Cheng, Qing; Jiao, Yuling; Huang, Jian; Yang, Can; Liu, Jin
Article

Bayesian Weighted Mendelian Randomization for Causal Inference Based on Summary Statistics

Bioinformatics, v. 36, (5), March 2020, p. 1501-1508
Zhao, Jia; Ming, Jingsi; Hu, Xianghong; Chen, Gang; Liu, Jin; Yang, Can
Article

BIVAS: A Scalable Bayesian Method for Bi-Level Variable Selection With Applications

Journal of Computational and Graphical Statistics, v. 29, (1), January 2020, p. 40-52
Cai, Mingxuan; Dai, Mingwei; Ming, Jingsi; Peng, Heng; Liu, Jin; Yang, Can
Article

CoMM-S²: A Collaborative Mixed Model Using Summary Statistics in Transcriptome-Wide Association Studies

Bioinformatics, v. 36, (7), April 2020, p. 2009-2016
Yang, Yi; Shi, Xingjie; Jiao, Yuling; Huang, Jian; Chen, Min; Zhou, Xiang; Sun, Lei; Lin, Xinyi; Yang, Can; Liu, Jin
Article

Direct-To-Consumer Genetic Testing in China and Its Role in GWAS Discovery and Replication

Quantitative Biology, 18 July 2020
Kang, Kang; Sun, Xue; Wang, Lizhong; Yao, Xiaotian; Tang, Senwei; Deng, Junjie; Wu, Xiaoli; Yang, Can; Chen, Gang; WeGene Research Team
Article

Exploring the Relationship Between Psychiatric Traits and the Risk of Mouth Ulcers Using Bi-Directional Mendelian Randomization

Frontiers in Genetics, v. 11, 16 December 2020, article number 608630
Wang, Kai; Ding, Lin; Yang, Can; Hao, Xingjie; Wang, Chaolong
Article

IGREX for quantifying the impact of genetically regulated expression on phenotypes

NAR Genomics and Bioinformatics, v. 2, (1), March 2020, article number lqaa010
Cai, Mingxuan; Chen, Lin S.; Liu, Jin; Yang, Can
Article

MR-LDP: a two-sample Mendelian randomization for GWAS summary statistics accounting for linkage disequilibrium and horizontal pleiotropy

NAR Genomics and Bioinformatics, v. 2, (2), June 2020, article number lqaa028
Cheng, Qing; Yang, Yi; Shi, Xingjie; Yeung, Kar-Fu; Yang, Can; Peng, Heng; Liu, Jin
Article

Testing and Controlling for Horizontal Pleiotropy With Probabilistic Mendelian Randomization in Transcriptome-Wide Association Studies

Nature Communications, v. 11, (1), 1 December 2020, article number 3861
Yuan, Zhongshang; Zhu, Huanhuan; Zeng, Ping; Yang, Sheng; Sun, Shiquan; Yang, Can; Liu, Jin; Zhou, Xiang
Article

Learning Hybrid Representations for Automatic 3D Vessel Centerline Extraction

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), v. 12266 LNCS, 2020, p. 24-34
He, Jiafa; Pan, Chengwei; Yang, Can; Zhang, Ming; Wang, Yang; Zhou, Xiaowei; Yu, Yizhou
Conference paper

2019 11

CoMM: A Collaborative Mixed Model to Dissecting Genetic Contributions to Complex Traits by Leveraging Regulatory Information

Bioinformatics (Oxford, England), v. 35, (10), May 2019, p. 1644-1652
Yang, Can; Wan, Xiang; Lin, Xinyi; Chen, Mengjie; Zhou, Xiang; Liu, Jin
Article

Detection of Cell-type-specific Risk-CpG Sites in Epigenome-wide Association Studies

Nature Communications, v. 10, (1), July 2019, article number 3113
Luo, Xiangyu; Yang, Can; Wei, Yingying
Article

Joint Analysis of Individual-level and Summary-level GWAS Data by Leveraging Pleiotropy

Bioinformatics, v. 35, (10), May 2019, p. 1729-1736
Dai, Mingwei; Wan, Xiang; Peng, Hao; Wang, Yao; Liu, Yue; Liu, Jin; Xu, Zongben; Yang, Can
Article

LPM: A Latent Probit Model to Characterize the Relationship Among Complex Traits Using Summary Statistics From Multiple GWASs and Functional Annotations

Bioinformatics, v. 36, (8), April 2020, p. 2506-2514
Ming, Jingsi; Wang, Tao; Yang, Can
Article

Prediction analysis for microbiome sequencing data

Biometric Methodology, v. 75, (3), April 2019, p. 875-884
Wang, Tao; Yang, Can; Zhao, Hongyu
Article

VIMCO: Variational Inference for Multiple Correlated Outcomes in Genome-wide Association Studies

Bioinformatics, v. 35, (19), October 2019, p. 3693-3700
Shi, Xingjie; Jiao, Yuling; Yang, Yi; Cheng, Chingyu; Yang, Can; Lin, Xinyi; Liu, Jin
Article

Comparison of Facial Emotion Recognition Based on Image Visual Features and EEG Features

Communications in Computer and Information Science, v. 1006, 2019, p. 162-172
Long, Yanfang; Kong, Wanzeng; Ling, Wenfen; Yang, Can; Zhu, Jieyong
Conference paper

Deep Generative Learning via Variational Gradient Flow

Proceedings of Machine Learning Research, v. 97, 2019, p. 2093-2101
Gao, Yuan; Jiao, Yuling; Wang, Yang; Yang, Can; Zhang, Shunkang
Conference paper

Deep Generative Learning via Variational Gradient Flow

36th International Conference on Machine Learning, ICML 2019, (Part 6), 2019, p. 3661-3669
Gao, Yuan; Jiao, Yuling; Wang, Yang; Wang, Yao; Yang, Can; Zhang, Shunkang
Conference paper

Facial Emotion Recognition Based on Brain and Machine Collaborative Intelligence

2019 IEEE International Conference on Computational Intelligence and Virtual Environments for Measurement Systems and Applications (CIVEMSA) / IEEE . IEEE, 2019, p. 1-5, Article number 9071606
Ling, Wenfen; Kong, Wanzeng; Long, Yanfang; Yang, Can; Jin, Xuanyu
Conference paper

Visualizing Emotional States: A Method Based on Human Brain Activity

Communications in Computer and Information Science, v. 1072, 2019, p. 248-258
Long, Yanfang; Kong, Wanzeng; Jin, Xuanyu; Shang, Jili; Yang, Can
Conference paper

2018 2

LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies

BMC Genomics, v. 19, (1), June 2018, article number 503, p. 1471-2164
Yang, Yi; Dai, Mingwei; Huang, Jian; Lin, Xinyi; Yang, Can; Chen, Min; Liu, Jin
Article

LSMM: A Statistical Approach to Integrating Functional Annotations With Genome-wide Association Studies

Bioinformatics, v. 34, (16), August 2018, p. 2788-2796
Ming, Jingsi; Dai, Mingwei; Cai, Mingxuan; Wan, Xiang; Liu, Jin; Yang, Can
Article

2017 4

IGESS: A Statistical Approach to Integrating Individual-Level Genotype Data and Summary Statistics in Genome-Wide Association Studies

Bioinformatics, v. 33, (18), September 2017, p. 2882-2889
Dai, Mingwei; Ming, Jingsi; Cai, Mingxuan; Liu, Jin; Yang, Can; Wan, Xiang; Xu, Zongben
Article

Leveraging Functional Annotations in Genetic Risk Prediction for Human Complex Diseases

PLoS Computational Biology, v. 13, (6), June 2017, article number e1005589, p. 1-16
Hu, Yiming; Lu, Qiongshi; Powles, Ryan; Yao, Xinwei; Yang, Can; Fang, Fang; Xu, Xinran; Zhao, Hongyu
Article

LLR: A Latent Low-rank Approach to Colocalizing Genetic Risk Variants in Multiple GWAS

Bioinformatics, v. 33, (24), December 2017, p. 3878-3886
Liu, Jin; Wan, Xiang; Wang, Chaolong; Yang, Chao; Zhou, Xiaowei; Yang, Can
Article

On Joint estimation of Gaussian graphical models for spatial and temporal data

Biometrics, v. 73, (3), September 2017, p. 769-779
Lin, Zhixiang; Wang, Tao; Yang, Can; Zhao, Hongyu
Article

2016 12

Analyzing Association Mapping in Pedigree-based GWAS Using A Penalized Multi-trait Mixed Model

Genetic Epidemiology, v. 40, (5), July 2016, p. 382-393
Liu, Jin; Yang, Can; Shi, Xingjie; Li, Cong; Huang, Jian; Zhao, Hongyu; Ma, Shuangge
Article

Computing Exact Permutation p-Values for Association Rules

Information Science, v. 346-347, June 2016, p. 146-162
Wu, Jun; He, Zengyou; Gu, Feiyang; Liu, Xiaoqing; Zhou, Jianyu; Yang, Can
Article

Efficient Drug-Pathway Association Analysis via Integrative Penalized Matrix Decomposition

IEEE/ACM Transactions on Computational Biology and Bioinformatics, v. 13, (3), May-June 2016, article number 7172456, p. 531-540
Li, Cong; Yang, Can; Hather, Greg; Liu, Ray; Zhao, Hongyu
Article

EPS: An Empirical Bayes Approach to Integrating Pleiotropy and Tissue-specific Information for Prioritizing Risk Genes

Bioinformatics, v. 32, (12), June 2016, p. 1856-1864
Liu, Jin; Wan, Xiang; Ma, Shuangge; Yang, Can
Article

Exploring the Genetic Patterns of Complex Diseases via the Integrative Genome-wide Approach

IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB), v. 13, (3), May-June 2016, article number 7164310, p. 557-564
Teng, Ben; Yang, Can; Liu, Jiming; Cai, Zhipeng; Wan, Xiang
Article

Mathematical Design of a Novel Gesture-based Instruction/input Device Using Wave Detection

SIAM Journal on Imaging Sciences, v. 9, (2), June 2016, p. 822-841
Liu, Hongyu; Wang, Yuliang; Yang, Can
Article

On high dimensional misspecified mixed model analysis in genome-wide association study

Annals of Statistics, v. 44, (5), October 2016, p. 2127-2160
Jiang, Jiming; Li, Cong; Paul, Debashis; Yang, Can; Zhao, Hongyu
Article

Simultaneous dimension reduction and adjustment for confounding variation

Proceedings of the National Academy of Sciences of the United States of America, v. 113, (51), 20 December 2016, p. 14662-14667
Lin, Zhixiang; Yang, Can; Zhu, Ying; Duchi, John; Fu, Yao; Wang, Yong; Jiang, Bai; Zamanighomi, Mahdi; Xu, Xuming; Li, Mingfeng; Sestan, Nenad; Zhao, Hongyu; Wong, Wing Hung
Article

Total Variation Regularized Tensor RPCA for Background Subtraction from Compressive Measurements

IEEE Transactions on Image Processing, v. 25, (9), September 2016, article number 7488247, p. 4075-4090
Cao, Wenfei; Wang, Yao; Sun, Jian; Meng, Deyu; Yang, Can; Cichoki, Andrzej; Xu, Zongben
Article

eQTL Mapping

Genome-Wide Association Studies: From Polymorphism to Personalized Medicine / Edited by Krishnarao Appasani. Cambridge : Cambridge University Press, 2016, p. 208-228, Ch. 14
Chen, Mengjie; Yang, Can; Li, Cong; Zhao, Hongyu
Book chapter

Introduction to Statistical Methods for Integrative Data Analysis in Genome-Wide Association Studies

Big Data Analytics in Genomics / Edited by Ka-Chun Wong. Cham : Springer, 2016, p. 3-23
Yang, Can; Wan, Xiang; Liu, Jin; Ng, Michael
Book chapter

Introduction to statistical methods in genome-wide association studies

Genome-Wide Association Studies: From Polymorphism to Personalized Medicine / Edited by Krishnarao Appasani. Cambridge : Cambridge University Press, 2016, p. 26-52, Ch. 3
Yang, Can; Li, Cong; Chung, Dongjun; Chen, Mengjie; Gelernter, Joel; Zhao, Hongyu
Book chapter

2015 6

A Penalized Regression Approach for Integrative Analysis in Genome- Wide Association Studies

Journal of Biometrics & Biostatistics, v. 6, (2), May 2015, article number 228
Liu, J.; Wang, F.; Gao, X.; Zhang, H.; Wan, X.; Yang, Can
Article

Dissecting Ancestry Genomic Background in Substance Dependence Genome-wide Association Studies

Pharmacogenomics, v. 16, (13), August 2015, p. 1487-1498
Polimanti, Renato; Yang, Can; Zhao, Hongyu; Gelernter, Joel
Article

Folded-concave Penalization Approaches to Tensor Completion

Neurocomputing, v. 152, March 2015, p. 261-273
Cao, Wenfei; Wang, Yao; Yang, Can; Chang, Xiangyu; Han, Zhi; Xu, Zongben
Article

Low-Rank Modeling and Its Applications in Image Analysis

ACM Computing Surveys, v. 47, (2), January 2015, article number 36
Zhou, Xiaowei; Yang, Can; Zhao, Hongyu; Yu, Weichuan
Article

Pervasive Pleiotropy Between Psychiatric Disorders and Immune Disorders Revealed by Integrative Analysis of Multiple GWAS

Human Genetics, v. 134, (11-12), November 2015, p. 1195-1209
Wang, Qian; Yang, Can; Gelernter, Joel; Zhao, Hongyu
Article

Drug-Pathway Association Analysis: Integration of High-Dimensional Transcriptional and Drug Sensitivity Profile

Integrating Omics Data / Edited by George Tseng, Debashis Ghosh, Xianghong Jasmine Zhou. New York, N.Y. : Cambridge University Press, 2015, p. 425-444
Li, Cong; Yang, Can; Hather, Greg; Liu, Ray; Zhao, Hongyu
Book chapter

2014 8

An International Effort Towards Developing Standards for Best Practices in Analysis, Interpretation and Reporting of Clinical Genome Sequencing Results in the CLARITY Challenge

Genome Biology, v. 15, (3), March 2014, article number R53
Brownstein, Catherine A.; Yang, Can
Article

Exploring the Genetic Architecture of Alcohol Dependence in African-Americans via Analysis of a Genomewide Set of Common Variants

Human Genetics, v. 133, (5), May 2014, p. 617-624
Yang, Can; Li, Cong; Kranzler, Henry R.; Farrer, Lindsay A.; Zhao, Hongyu; Gelernter, Joel
Article

GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation

PLoS Genetics, v. 10, (11), November 2014, article number e1004787, p. 1-14
Chung, Dongjun; Yang, Can; Li, Cong; Gelernter, Joel; Zhao, Hongyu
Article

Identification of Methylation Quantitative Trait Loci (mQTLs) Influencing Promoter DNA Methylation of Alcohol Dependence Risk Genes

Human Genetics, v. 133, (9), September 2014, p. 1093-1104
Zhang, Huiping; Wang, Fan; Kranzler, Henry R.; Yang, Can; Xu, Hongqin; Wang, Zuoheng; Zhao, Hongyu; Gelernter, Joel
Article

Improving Genetic Risk Prediction by Leveraging Pleiotropy

Human Genetics, v. 133, (5), May 2014, p. 639-650
Li, Cong; Yang, Can; Gelernter, Joel; Zhao, Hongyu
Article

A penalized linear mixed model for genomic prediction using pedigree structures

BMC Proceedings, v. 8, (Supplement 1), June 2014, article number S67
Yang, Can; Li, Cong; Chen, Mengjie; Chen, Xiaowei; Hou, Lin; Zhao, Hongyu
Conference paper

Adjustment of familial relatedness in association test for rare variants

BMC Proceedings, v. 8, (Supplement 1), June 2014, article number S39
Li, Cong; Yang, Can; Chen, Mengjie; Chen, Xiaowei; Hou, Lin; Zhao, Hongyu
Conference paper

Admixture mapping analysis in the context of GWAS with GAW18 data

BMC Proceedings, v. 8, (Supplement 1), June 2014
Chen, Mengjie; Yang, Can; Li, Cong; Hou, Lin; Chen, Xiaowei; Zhao, Hongyu
Conference paper

2013 8

Accounting for Non-genetic Factors by Low-rank Representation and Sparse Regression for eQTL Mapping

Bioinformatics, v. 29, (8), April 2013, p. 1026-1034
Yang, Can; Wang, Lin; Zhang, Shuqin; Zhao, Hongyu
Article

Archival Report: Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder

Biological Psychiatry, v. 74, (9), November 2013, p. 656-663
Xie, Pingxing; Kranzler, Henry R.; Yang, Can; Zhao, Hongyu; Farrer, Lindsay A.; Gelernter, Joel
Article

Empirical Bayes Correction for the Winner's Curse in Genetic Association Studies

Genetic Epidemiology, v. 37, (1), January 2013, p. 60-68
Ferguson, John P.; Cho, Judy H.; Yang, Can; Zhao, Hongyu
Article

HapBoost: A Fast Approach to Boosting Haplotype Association Analyses in Genome-Wide Association Studies

IEEE/ACM Transactions on Computational Biology and Bioinformatics, v. 10, (1), 2013, article number 6419694, p. 207-212
Wan, Xiang; Yang, Can; Yang, Qiang; Zhao, Hongyu; Yu, Weichuan
Article

Moving Object Detection by Detecting Contiguous Outliers in the Low-Rank Representation

IEEE Transactions on Pattern Analysis and Machine Intelligence, v. 35, (3), March 2013, article number 6216381, p. 597-610
Zhou, Xiaowei; Yang, Can; Yu, Weichuan
Article

Multisample aCGH Data Analysis via Total Variation and Spectral Regularization

IEEE/ACM Transactions on Computational Biology and Bioinformatics, v. 10, (1), January-February 2013, article number 6517420, p. 230-235
Zhou, Xiaowei; Yang, Can; Wan, Xiang; Zhao, Hongyu; Yu, Weichuan
Article

ProteinLasso: A Lasso regression approach to protein inference problem in shotgun proteomics

Computational Biology and Chemistry, v. 43, April 2013, p. 46-54
Huang, Ting; Gong, Haipeng; Yang, Can; He, Zengyou
Article

The Complete Compositional Epistasis Detection in Genome-wide Association Studies

BMC Genetics, v. 14, February 2013, article number 7
Wan, Xiang; Yang, Can; Yang, Qiang; Zhao, Hongyu; Yu, Weichuan
Article

2012 3

Peptide Reranking with Protein-Peptide Correspondence and Precursor Peak Intensity Information

IEEE/ACM Transactions on Computational Biology and Bioinformatics, v. 9, (4), July-August 2012, article number 6202798, p. 1212-1219
Yang, Chao; He, Zengyou; Yang, Can; Yu, Weichuan
Article

近邻自适应局部尺度的谱聚类算法

中国图象图形学报=Journal of Image and Graphics, v. 17, (4), 2012, p. 523-529
孔万增; 孙昌思核; 张建海; 胡三清; 楊燦
Article

Automatic Mitral Leaflet Tracking in Echocardiography by Outlier Detection in the Low-rank Representation

IEEE Conference on Computer Vision and Pattern Recognition, August 2012, article number 6247773, p. 972-979
Zhou, Xiaowei; Yang, Can; Yu, Weichuan
Conference paper

2011 6

A Hidden Two-locus Disease Association Pattern in Genome-wide Association Studies

BMC bioinformatics, v. 12, (156), May 2011, article number 156, p. 1-14
Yang, Can; Wan, Xiang; Yang, Qiang; Xue, Hong; Tang, Nelson L.S.; Yu, Weichuan
Article

A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data

IEEE/ACM Transactions on Computational Biology and Bioinformatics, v. 8, (2), March-April 2011, article number 5066962, p. 368-380
He, Zengyou; Yang, Can; Yu, Weichuan
Article

GBOOST: a GPU-based Tool for Detecting Gene-gene Interactions in Genome-wide Case Control Studies

Bioinformatics, v. 27, (9), May 2011, article number btr114, p. 1309-1310
Yung, Ling Sing; Yang, Can; Wan, Xiang; Yu, Weichuan
Article

Identifying Disease-associated SNP Clusters via Contiguous Outlier Detection

Bioinformatics, v. 27, (18), September 2011, article number btr424, p. 2578-2585
Yang, Can; Zhou, Xiaowei; Wan, Xiang; Yang, Qiang; Xue, Hong; Yu, Weichuan
Article

Motif-All: Discovering All Phosphorylation Motifs

BMC Bioinformatics, v. 12, (supplement 1), February 2011, article number S22
He, Zengyou; Yang, Can; Guo, Guangyu; Li, Ning; Yu, Weichuan
Article

The Choice of Null Distributions for Detecting Gene-Gene Interactions in Genome-Wide Association Studies

BMC Bioinformatics, v. 12, (Supplement 1), February 2011, article number S26
Yang, Can; Wan, Xiang; He, Zengyou; Yang, Qiang; Xue, Hong; Yu, Weichuan
Conference paper

2010 6

A Regularized Method for Peptide Quantification

Journal of Proteome Research, v. 9, (5), May 2010, p. 2705-2712
Yang, Chao; Yang, Can; Yu, Weichuan
Article

BOOST: A Fast Approach to Detecting Gene-Gene Interactions in Genome-wide Case-Control Studies

American Journal of Human Genetics, v. 87, (3), September 2010, p. 325-340
Wan, Xiang; Yang, Can; Yang, Qiang; Xue, Hong; Fan, Xiaodan; Tang, Nelson L.S.; Yu, Weichuan
Article

Detecting Two-locus Associations Allowing for Interactions in Genome-wide Association Studies

Bioinformatics, v. 26, (20), August 2010, article number btq486, p. 2517-2525
Wan, Xiang; Yang, Can; Yang, Qiang; Xue, Hong; Tang, Nelson L.S.; Yu, Weichuan
Article

Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification

Journal of Computational Biology, v. 17, (3), March 2010, p. 221-235
He, Zengyou; Yang, Chao; Yang, Can; Qi, Robert Zhong; Tam, P.M.; Yu, Weichuan
Article

Predictive Rule Inference for Epistatic Interaction Detection in Genome-wide Association Studies

Bioinformatics, v. 26, (1), January 2010, article number btp622, p. 30-37
Wan, Xiang; Yang, Can; Yang, Qiang; Xue, Hong; Tang, Nelson L.S.; Yu, Weichuan
Article

Identifying Main Effects and Epistatic Interactions from Large-scale SNP Data via Adaptive Group Lasso

BMC Bioinformatics, v. 11, (Supplement 1), January 2010, article number S18
Yang, Can; Wan, Xiang; Yang, Qiang; Xue, Hong; Yu, Weichuan
Conference paper

2009 2

MegaSNPhunter: a Learning Approach to Detect Disease Predisposition SNPs and High Level Interactions in Genome Wide Association Study

BMC Bioinformatics, v. 10, January 2009, article number 13
Wan, Xiang; Yang, Can; Yang, Qiang; Xue, Hong; Tang, Nelson L.S.; Yu, Weichuan
Article

SNPharvester: a Filtering-based Approach for Detecting Epistatic Interactions in Genome-wide Association Studies

Bioinformatics, v. 25, (4), February 2009, p. 504-511
Yang, Can; He, Zengyou; Wan, Xiang; Yang, Qiang; Xue, Hong; Yu, Weichuan
Article

2008 3

Peak bagging for peptide mass fingerprinting

Bioinformatics, v. 24, (10), May 2008, p. 1293-1299
He, Zengyou; Yang, Can; Yu, Weichuan
Article

Model Free Data Mining

Data Mining and Knowledge Discovery Technologies / Edited by: David Taniar. Hershey, PA, USA : IGI Publishing, 2008, p. 224-252
Yang, Can; Meng, Jun; Zhu, Shanan; Dai, Mingwei
Book chapter

GPC Algorithm and Queuing-selecting for Networked Level Control

IEEE International Conference on Control and Automation ICCA, 2008, p. 2626-2629
Kong, Wanzeng; Zhu, Shan-an; Yang, Can
Conference paper

2006 3

Application of Generalized Predictive Control in Networked Control System

Journal of Zhejiang University: Science, v. 7, (2), February 2006, p. 225-233
Yang, Can; Zhu, Shan-an; Kong, Wan-zeng; Lu, Li-ming
Article

Cluster-Based Input Selection for Transparent Fuzzy Modeling

International Journal of Data Warehousing and Mining, v. 2, (3), 2006, p. 57-75
Yang, Can; Meng, Jun; Zhu, Shanan
Article

基于人类知识的多变量多层模煳解耦控制策略研究

Sixth World Congress on Intelligent Control and Automation, Danvers, MA, U.S. : Institute of Electrical and Electronics Engineers, Inc., 2006, p. 3867-3871
孟濬; 杨灿
Conference paper

2005 2

Optimal Fuzzy Modeling Based on Minimum Cluster Volume

ADMA 2005: Advanced Data Mining and Applications, Editors: Xue Li, Shuliang Wang, Zhao Yang Dong. Heidelberg : Springer Verlag, 2005, p. 232-239
Yang, Can; Meng, Jun
Conference paper

Transparent Fuzzy Modeling Based on Minimum Cluster Volume

2005 International Conference on Control and Automation (ICCA), Danvers, MA : IEEE, 2005, p. 1120-1125
Yang, Can; Zhu, Shan-an; Meng, Jun; Lu, Li-ming
Conference paper

MATH4432	Statistical Machine Learning
MATH4999	Independent Capstone Project
MATH5472	Computer Age Statistical Inference with Applications
MATH6912A	Reading Course: Deep Learning and Its Applications
MATH6912B	Reading Course: Artificial Intelligence Methods for Science
MATH6912L	Reading Course: Deep Learning Methods with Their Applications

MAFS5340	Machine Learning and Its Applications
MATH6911X	Reading Course: Deep Learning Methods and Applications
MFIT5010	Statistical Machine Learning
MSBD5013	Statistical Prediction
UROP1100L	Undergraduate Research Opportunities Series 1

MATH4432	Statistical Machine Learning
MATH5472	Computer Age Statistical Inference with Applications
MATH6911F	Reading Course: Deep Learning for 3D Version

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2005 2

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Article 8

Article 5

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Book chapter 1

Conference paper 1

Article 9

Conference paper 1

Article 6

Conference paper 5

Article 2

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Book chapter 3

Article 5

Book chapter 1

Article 5

Conference paper 3

Article 8

Article 2

Conference paper 1

Article 5

Conference paper 1

Article 5

Conference paper 1

Article 2

Article 1

Book chapter 1

Conference paper 1

Article 2

Conference paper 1

Conference paper 2

2018 2

2017 4

2016 12

2015 6

2014 8

2013 8

2012 3

2011 6

2010 6

2009 2

2008 3

2006 3

2005 2

Teaching Assignment

Research Postgraduate (RPG) Supervision

From January 2021 to December 2024 (As of 21 November 2024)

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Graduated RPGs

Projects

From January 2022 to December 2024

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