Faculty Profiles - FU Amy Kit Yu | The Hong Kong University of Science and Technology

2024 5

A blood-based multi-pathway biomarker assay for early detection and staging of Alzheimer's disease across ethnic groups

Alzheimer's and Dementia, v. 20, (3), January 2024, p. 2000-2015
Jiang, Yuanbing; Uhm, Hyebin; Ip, Fanny C.; Ouyang, Li; Lo, Ronnie M. N.; Cheng, Elaine Y. L.; Cao, Xiaoyun; Tan, Clara M. C.; Law, Brian C. H.; Ortiz-Romero, Paula; Puig-Pijoan, Albert; Fernández-Lebrero, Aida; Contador, José; Mok, Kin Ying Boniface; Hardy, John; Kwok, Timothy C. Y.; Mok, Vincent C. T.; Suárez-Calvet, Marc; Zetterberg, Henrik; Fu, Amy K. Y.; Ip, Nancy Yuk-yu
Article

Using blood transcriptome analysis for Alzheimer's disease diagnosis and patient stratification

Alzheimers & Dementia, v. 20, (4), April 2024, p. 2469-2484
Zhong, Huan; Zhou, Xiaopu; Uhm, Hyebin; Jiang, Yuanbing; Cao, Han; Chen, Yu; Mak, Tiffany T. W.; Lo, Ronnie Ming Nok; Wong, Bonnie Wing Yan; Cheng, Elaine Yee Ling; Mok, Kin Ying Boniface; Chan, Andrew Lung Tat; Kwok, Timothy C. Y.; Mok, Vincent C. T.; Ip, Fanny Chui Fun; Hardy, John; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Understanding the Biomarkers of Alzheimer's Disease - Insights into the Development of Diagnosis

Fu, Kit Yu
Conference paper

2023 6

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Communications Medicine, v. 3, April 2023, article number 49
Alzheimer’s Disease Neuroimaging Initiative; Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Lv, Ge; Zhang, Huan; Chen, Jiahang; Ye, Tao; Chen, Yuewen; Zhang, Yulin; Ma, Shuangshuang; Lo, Ronnie M.N.; Tong, Pui Sze; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Guo, Qihao; Mok, Kin Ying Boniface; Shoai, Maryam; Hardy, John; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Receptor-ligand interaction controls microglial chemotaxis and amelioration of Alzheimer's disease pathology

Journal of Neurochemistry, v. 166, (6), September 2023, p. 891-903
Lau, Shun Fat; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

The VCAM1–ApoE pathway directs microglial chemotaxis and alleviates Alzheimer’s disease pathology

Nature Aging, v. 3, (10), October 2023, p. 1219-1236
Lau, Shun Fat; Wu, Wei; Wong, Hiu Yi; Ouyang, Li; Qiao, Yi; Xu, Jiahui; Lau, Hiu Yan; Wong, Carlton; Jiang, Yuanbing; Holtzman, David M.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Using Deep Learning Models to Examine the Biological Impact of Polygenic Risks for Alzheimer’s Disease

Alzheimer's & Dementia, v. 19, (S1), June 2023, article number e065377, Supplement: Basic Science and Pathogenesis
Zhou, Xiaopu; Ip, Fanny Chui Fun; Lv, Ge; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Discovery of a high-performance blood protein biomarker panel for Alzheimer's disease screening and staging

Fu, Kit Yu
Conference paper

Understanding the roles of interleukin-33/ST2 signaling in Alzheimer’s disease

Fu, Kit Yu
Conference paper

2022 8

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Nature Aging, v. 2, (7), July 2022, p. 616-634
Jiang, Yuanbing; Zhou, Xiaopu; Wong, Hiu Yi; Ouyang, Li; Ip, Fanny Chui Fun; Chau, Man Ni; Lau, Shun Fat; Wu, Wei; Wong, Yew Kit Daniel; Seo, Heukjin; Fu, Wing Yu; Lai, Chit Hang; Chen, Yuewen; Chen, Yu; Tong, Pui Sze; Alzheimer’s Disease Neuroimaging Initiative; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Mok, Kin Ying Boniface; Shoai, Maryam; Lehallier, Benoit; Losada, Patricia Moran; O'Brien, Eleanor; Porter, Tenielle; Laws, Simon M.; Hardy, John; Wyss-Coray, Tony; Masters, Colin L.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Association of SPI1 haplotypes with altered SPI1 gene expression and Alzheimer’s disease risk

Journal of Alzheimer's Disease, v. 86, (4), April 2022, p. 1861-1873
Cao, Han; Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Chen, Yuewen; Lai, Chit Hang; Lo, Ming Nok; Tong, Pui Sze; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Alzheimer’s Disease Neuroimaging Initiative; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice

Nature Biomedical Engineering, v. 6, (2), February 2022, p. 168-180
Duan, Yangyang; Ye, Tao; Qu, Zhe; Chen, Yuewen; Miranda, Abigail Orquiza; Zhou, Xiaopu; Lok, Ka Chun; Chen, Yu; Fu, Kit Yu; Gradinaru, Viviana; Ip, Nancy Yuk-yu
Article

Demographics and Medication Use of Patients with Late-Onset Alzheimer’s Disease in Hong Kong

Journal of Alzheimer's Disease, v. 87, (3), May 2022, p. 1205-1213
Wong, Hiu Yi; Zhong, Huan; Zhou, Xiaopu; Chan, Phillip Y.C.; Kwok, Timothy C.Y.; Mok, Kin; Hardy, John; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms

The FEBS Journal, v. 289, (8), April 2022, p. 2202-2218
Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging

Alzheimer's & Dementia, v. 18, (1), January 2022, p. 88-102
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Nicole C. H.; Cheung, Kit; Lo, Ronnie M. N.; Tong, Pui Sze; Wong, Bonnie W. Y.; Chan, Andrew L. T.; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Multi-Omics-Based Autophagy-Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology

Advanced Science, 13 June 2022, article number 2201212
Park, Jong-Chan; Barahona-Torres, Natalia; Jang, So-Young; Mok, KinY.; Kim, HaengJun; Han, Sun-Ho; Cho, Kwang-Hyun; Zhou, Xiaopu; Fu, Amy K.Y.; Ip, Nancy Yuk-yu; Seo, Jieun; Choi, Murim; Jeong, Hyobin; Hwang, Daehee; Lee, Dong Young; Byun, Min Soo; Yi, Dahyun; Han, Jong Won; Mook-Jung, Inhee; Hardy, John
Article

An IL1RL1 genetic variant lowers soluble ST2 levels and attenuates the impact of APOE-ε4 in Alzheimer's disease

Jiang, Yuanbing; Zhou, Xiaopu; Wong, Hiu Yi; Ouyang, Li; Ip, Fanny Chui Fun; Chau, Man Ni; Lau, Shun Fat; Wu, Wei; Seo, Heukjin; Fu, Wing Yu; Lai, Chit Hang; Chen, Yuewen; Chen, Yu; Tong, Pui Sze; Alzheimer's Disease Neuroimaging Initiative; Mok, Vincent C.T.; Kwok, Timothy C. Y.; Lehallier, Benoit; Losada, Patricia Morán; O'Brien, Eleanor; Porter, Tenielle; Laws, Simon M.; Wyss-Coray, Tony; Masters, Colin L.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

2021 14

APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention

Current Opinion in Neurobiology, v. 69, August 2021, p. 58-67
Zhou, Xiaopu; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus

Proceedings of the National Academy of Sciences of the United States of America, v. 118, (1), January 2021, article number e2020810118
Wang, Ye; Fu, Wing Yu; Cheung, Kit; Hung, Kwok Wang; Chen, Congping; Geng, Hongyan; Yung, Wing Ho; Qu, Jianan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Blood transcriptome analysis for Alzheimer' disease in Hong Kong Chinese population

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, v. 17, (S3), December 2021, article number e056643
Zhong, Huan; Zhou, Xiaopu; Jiang, Yuanbing; Chen, Yu; Lai, N.C.H.; Tong, Pui Sze; Lo, Ronnie M.N.; Kwok, Timonthy C.Y.; Mok, Vincent C.T.; Ip, Fanny Chui Fun; Mok, Kin Ying Boniface; Hardy, John; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Cellular and Molecular Life Sciences, 13 April 2021
Lau, Shun Fat; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Deep learning for polygenic score analysis for Alzheimer's disease risk prediction in the Chinese population

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, v. 17, (S3), December 2021, article number e056625
Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Yuewen; Chen, Jiahang; Zhang, Yulin; Ma, Shuangshuang; Lai, Nicole Chit Hang; Lo, Ronnie M.N.; Cheung, Kit; Tong, Pui Sze; Mok, Kin Ying Boniface; Hardy, John; Guo, Qihao; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

Communications Biology, v. 4, (1), February 2021, article number 195
Ye, Tao; Duan, Yangyang; Tsang, Hayley Wing Sum; Xu, He; Chen, Yuewen; Cao, Han; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry

DNA and Cell Biology, v. 40, (9), September 2021, p. 1125-1130
Wang, Ye; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

Scientific Reports, v. 11, (1), February 2021, article number 4359
Lau, Ka Yan Jackie; Tian, Min; Shen, Yang; Lau, Shun Fat; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Polygenic Score Models For Alzheimer’s Disease: From Research To Clinical Applications

Frontiers in Neuroscience, v. 15, 29 March 2021, article number 650220
Zhou, Xiaopu; Li, Yolanda Yuen Tung; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model

STAR Protocols, v. 2, (1), March 2021, article number 100265
Lau, Shun Fat; Wu, Wei; Seo, Heukjin; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Rhynchophylline Administration Ameliorates Amyloid-beta Pathology and Inflammation in an Alzheimer's Disease Transgenic Mouse Model

ACS Chemical Neuroscience, v. 12, (22), November 2021, p. 4249-4256
Fu, Wing Yu; Hung, Kwok Wang; Lau, Shun Fat; Butt, Busma; Yuen, Wai Hin; Fu, Guangmiao; Chan, Chi Wai; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

A high-performance biomarker panel for Alzheimer's disease screening and staging identified by large-scale plasma proteomic profiling

Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Chit Hang; Cheung, Kit; Lo, Ming Nok; Tong, Pui Sze; Wong, Wing Yan; Chan, Andrew L.T.; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

A high-performance biomarker panel for Alzheimer's disease screening and staging identified by large-scale plasma proteomic profiling

The Journal of the Alzheimer’s Association, v. 17, (S5), December 2021, article number e056099, Supplement: Biomarkers – Part 2
Jiang, Yuanbing; Zhou, Xiaopu; Ip, Fanny Chui Fun; Chan, Philip; Chen, Yu; Lai, Chit Hang; Cheung, Kit; Lo, Ming Nok; Tong, Pui Sze; Wong, Wing Yan; Chan, Andrew L.T.; Mok, Vincent C.T.; Kwok, Timonthy C.Y.; Mok, Kin Ying Boniface; Hardy, John; Zetterberg, Henrik; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

Deep learning for polygenic score analysis for Alzheimer’s disease risk prediction in the Chinese population

Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Jiang, Yuanbing; Cao, Han; Zhong, Huan; Chen, Yuewen; Chen, Jiahang; Zhang, Yulin; Ma, Shuangshuang; Lai, Chit Hang; Lo, Ming Nok; Cheung, Kit; Tong, Pui Sze; Mok, Kin Ying Boniface; Hardy, John; Guo, Qihao; Mok, Vincent C. T.; Kwok, Timothy C. Y.; Chen, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2020 4

Genetic and polygenic risk score analysis for Alzheimer’s disease in the Chinese population

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, v. 12, (1), August 2020, article number e12074
Zhou, Xiaopu; Chen, Yu; Ip, Fanny Chui Fun; Lai, Nicole C.H.; Li, Yuen Tung; Jiang, Yuanbing; Zhong, Huan; Chen, Yuewen; Zhang, Yulin; Ma, Shuangshuang; Lo, Ronie M.N.; Cheung, Kit; Tong, Pui Sze; Ko, Ho; Shoai, Maryam; Mok, Kin Ying Boniface; Hardy, John; Mok, Vincent C.T.; Kwok, Timothy C.Y.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease

Cell Reports, v. 31, (3), April 2020, article number 107530
Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

p39-associated Cdk5 activity regulates dendritic morphogenesis

Scientific Reports, v. 10, (1), December 2020, article number 18746
Ouyang, Li; Chen, Yu; Wang, Ye; Chen, Yuewen; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-yu
Article

Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America, v. 117, (41), 13 October 2020, p. 25800-25809
Lau, Shun Fat; Cao, Han; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

2019 11

Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer's Disease

ACS Chemical Neuroscience, v. 10, (9), August 2019, p. 3986-3996
Chen, Yuewen; Xu, Jinying; Zhou, Xiaopu; Liu, Saijuan; Zhang, Yulin; Ma, Shuangshuang; Fu, Kit Yu; Ip, Nancy Yuk-yu; Chen, Yu
Article

Increased Axin expression enhances adult hippocampal neurogenesis and exerts an antidepressant effect

Scientific Reports, v. 9, February 2019, article number 1190, p. 1-10
Chen, Weiwei; Fu, Wing Yu; Su, Yiting; Fang, Weiqun; Fu, Amy K. Y.; Ip, Nancy Yuk-yu
Article

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Nature Communications, v. 10, (1), December 2019, article number 3310
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Kwok, Timothy C. Y.; Mok, Vincent C. T.; Guo, Qihao; Ip, Chui Fun Fanny; Chen, Yuewen; Mullapudi, Nandita; Giusti-Rodríguez, Paola; Sullivan, Patrick F.; Hardy,John; Fu, Kit Yu; Li, Yun; Ip, Nancy Yuk-yu
Article

Synaptic Dysfunction in Alzheimer's Disease: Mechanisms and Therapeutic Strategies

Pharmacology and Therapeutics, v. 195, March 2019, p. 186-198
Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

α2-chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis

Proceedings of the National Academy of Sciences of the United States of America, v. 116, (27), June 2019, p. 13651-13660
Su, Yiting; Lau, Shun Fat; Ip, P.K. Jacque; Cheung, Kit; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Deregulation of IL-33/ST2 signaling in Alzheimer’s disease

Jiang, Yuanbing; Zhou, Xiaopu; Wang, Ye; Lai, N.C.H.; Tong, Pui Sze; Mok, V.C.T.; Kwok, T.C.Y.; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

IL-33/ST2 signaling promotes excitatory synapse formation in the hippocampus

Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

IL-33-dependent transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease

Lau, Shun Fat; Chen, Congping; Fu, Wing Yu; Qu, Jianan; Cheung, Hiu Tung; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Kwok, T.C.Y.; Mok, V.C.T.; Guo, Q.; Ip, Fanny C.F.; Chen, Y.; Mullapudi, Nandita; Hardy, J.; Fu, Kit Yu; Li, Y.; Ip, Nancy Yuk-yu
Conference paper

Role of IL-33/ST2 signaling in homeostatic synaptic plasticity in the hippocampus

Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Whole-genome sequencing for Alzheimer’s disease risk in the Chinese population

Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Mok, V.C.T.; Guo, Q.; Ip, Fanny C.F.; Chen, Y.; Hardy, J.; Li, Y.; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

2018 3

Identification of Genetic Risk Factors in The Chinese Population Implicates a Role of the Immune System in Alzheimer’s Disease Pathogenesis

Proceedings of the National Academy of Sciences of the United States of America, v. 115, (8), February 2018, p. 1697-1706
Zhou, Xiaopu; Chen, Yu; Mok, Kin Ying Boniface; Zhao, Qianhua; Chen, Keliang; Chen, Yuewen; Hardy, John; Li, Yun; Fu, Kit Yu; Guo, Qihao; Ip, Nancy Yuk-yu
Article

Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs

Scientific Reports, v. 8, (1), May 2018, article number 7377, p. 1-7
Gu, shuo; Fu, Wing Yu; Fu, Kit Yu; Tong, Pui See; Ip, Fanny Chui-Fun; Huang, Xuhui; Ip, Nancy Yuk-Yu
Article

IL-33/ST2 signaling enhances the formation of excitatory synapses in the hippocampus

Wang, Ye; Hung, Kwok Wang; Chuang, Ching Yi; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2017 5

Cdk5-Dependent Phosphorylation of Liprinα1 Mediates Neuronal Activity-Dependent Synapse Development

Proceedings of the National Academy of Sciences of the United States of America, v. 114, (33), August 2017, p. E6992-E7001
Huang, Huiqian; Lin, Xiaochen; Liang, Zhuoyi; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Homeostatic Scaling of AMPA Receptors by Semaphorin

Neuron, v. 96, (5), 6 December 2017, p. 955-958
Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Regulation of postsynaptic signaling in structural synaptic plasticity

Current Opinion in Neurobiology, v. 45, Aug 2017, p. 148-155
Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Activation of the melanocortin 4 receptor signaling pathway ameliorates Alzheimer’s disease-like pathology

Tian, Min; Shen, Yang; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

IL-33 enhances the development of hippocampal excitatory synapses

Hung, Kwok Wang; Wang, Ye; Chuang, Ching Yi; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

2016 16

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline

Proceedings of the National Academy of Sciences of the United States of America, v. 113, (19), May 2016, p. 2705-2713
Fu, Kit Yu; Hung, Kwok Wang; Yuen, Yat Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, Chi Wai; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu
Article

Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer’s Disease Model

Cell Reports, v. 17, (7), November 2016, p. 1819-1831
Shen, Yang; Tian, Min; Zheng, Yuqiong; Gong, Fei; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Cdk5 Activity is Required for EphB-mediated Synaptogenesis

Chen, Yu; Wong, Yung Hou; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-mediated Phosphorylation of Liprinα1 is Critical for Synaptic Plasticity

Huang, Huiqian; Lin, Xiaochen; Liang, Zhuoyi; Zhao, Teng; Du, Shengwang; Loy, Michael Ming-tak; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

Characterization of Pathogenic Mutations and Cellular Phenotypes of Alzheimer’s Disease using Human Induced Pluripotent Stem Cells

Ip, Nancy Yuk-Yu; Fu, Kit Yu; Tong, Pui Sze; Tu, X.; Ye, Tao
Conference paper

Coronin 2B is an Important Regulator of Neuronal Polarization

Chen, Yu; Chen, Y.; Zhang, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Elucidation of the Functional Roles of Rho GTPase-activating Proteins in Adult Neurogenesis

Su, Yiting; Ip, Pak Kan; Min, Lan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Elucidation of the Functional Roles of Rho GTPase-Activating Proteins in Adult Neurogenesis

Su, Yiting; Ip, Nancy Yuk-Yu; Min, L.; Ip, Pak Kan; Fu, Kit Yu
Conference paper

Fine Mapping of the APOE Locus by Low-pass Whole-genome Sequencing in Chinese Alzheimer’s Disease Patients

Zhou, Xiaopu; Chen, Yu; Zhao, Q.; Chu, M.K.M.; Kwok, C.T.; Mok, K.Y.; Zhang, B.; Fu, Kit Yu; Li, Y.; Guo, Q.; Ip, Nancy Yuk-yu
Conference paper

Functional roles of Rho GTPase-activating proteins in adult neurogenesis

Su, Yiting; Ip, Nancy Yuk-Yu; Ip, Pak Kan; Min, L.; Fu, Kit Yu
Conference paper

IL-33 Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline

Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, Deejay S.Y.; Chan, I.C.W.; Cheung, Tom H.; Zhang, Baorong; Fu, Wing Yu; Liew, Foo Y.; Ip, Nancy Yuk-yu
Conference paper

IL-33 ameliorates cognitive deficits and amyloid pathology in an Alzheimer’s disease-like mouse model

Fu, Kit Yu; Hung, Kwok Wang; Yuen, M.Y.F.; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Cheung, Tom; Zhang, B; Fu, Wing Yu; Liew, F.Y.; Ip, Nancy Yuk-yu
Conference paper

IL-33 modulates microglial innate immunity in an Alzheimer’s disease-like mouse model

Zhou, Xiaopu; Ip, Nancy Yuk-yu; Cheung, Tom; Liew, F.Y.; Chan, I.C.W.; Mak, D.S.Y.; Yuen, M.Y.F.; Hung, Kwok Wang; Fu, Kit Yu; Fu, Wing Yu
Conference paper

IL-33 Modulates the Inflammatory Response in the Brains of Alzheimer’s disease mouse model

Fu, Wing Yu; Fu, Kit Yu; Hung, Kwok Wang; Yuen, Matthew Ming Fai; Zhou, Xiaopu; Mak, D.S.Y.; Chan, I.C.W.; Liew, F.Y.; Cheung, Tom H.; Ip, Nancy Yuk-yu
Conference paper

MC4R Activation Alleviates Amyloid-Beta–Induced Synaptic Dysfunction

Gong, Fei; Shen, Yang; Tian, Min; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Understanding the Melanocortin Microcircuit in the Mouse Hippocampus

Tian, Min; Ip, Nancy Yuk-Yu; Fu, Kit Yu; Zheng, Y.Q.; Shen, Yang
Conference paper

2015 14

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling

PLoS ONE, v. 10, (7), July 2015, article number e0133115
Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Chen, Yuewen; Zhou, Xiaopu; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-yu
Article

Cdk5 regulates activity-dependent gene expression and dendrite development

Journal of Neuroscience, v. 35, (45), November 2015, p. 15127-15134
Liang, Zhuoyi; Ye, Tao; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk Yu
Article

Emerging roles of axin in cerebral cortical development

Frontiers in Cellular Neuroscience, v. 9, June 2015, article number 217, p. 1-8
Ye, Tao; Fu, Kit Yu; Ip, Nancy Y.Y.
Article

Neddylation is needed for synapse maturation

Nature Neuroscience, v. 18, (2), February 2015, p. 164-166
Fu, Kit Yu; Ip, Nancy Y.Y.
Article

NRC-interacting factor directs neurite outgrowth in an activity-dependent manner

Neuroscience, v. 289, March 2015, p. 207-213
Zhao, Xiao Su; Fu, Wing Yu; Hung, Kwok Wang; Chien, Winnie W.Y.; Li, Zhongrui; Fu, Kit Yu; Ip, Nancy Y.Y.
Article

S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength

Nature Communications, v. 6, October 2015, article number 8665
Zhang, Peng; Fu, Wingyu; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

Activity-Dependent Regulation of Liprinα1 Phosphorylation During Synapse Development

Huang, Huiqian; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Axin Regulates Dendritic Spine Development via Cdc42 Signaling

Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Zhou, Xiaopu; Fang, Weiqun; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development

Liang, Zhuoyi; Ye, Tao; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

Melanocortin 4 Receptor Signaling Modulation Ameliorates Synaptic Dysfunction in Alzheimer's Disease Models

Tian, Min; Shen, Yang; Cheng, Yee Ling; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Role of Cdk5 in Activity-Induced Gene Expression and Dendrite Development

Ye, Tao; Liang, Zhuoyi; Zhou, Xiaopu; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-yu
Conference paper

S-Nitrosylation–Dependent Proteasomal Degradation Restricts cdk5 Activity to Regulate Hippocampal Synaptic Strength

Fu, Kit Yu; Zhang, Peng; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

The EphA4 Inhibitor Rhynchophylline Ameliorates Disease Pathology in a Mouse Model of Alzheimer's Disease

Fu, Wing Yu; Butt, Busma Wai Yin; Hung, Kwok Wang; Ip, Fanny Chui Fun; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2014 29

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America, v. 111, (27), July 2014, p. 9959-9964
Fu, Amy Kit Yu; Hung, Kwok Wang; Huang, Huiqian; Gu, Shuo; Shen, Yang; Cheng, Elaine Yee Ling; Ip, Fanny C.F.; Huang, Xuhui; Fu, Wing Yu; Ip, Nancy Yuk Yu
Article

Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition

Journal of Neuroscience, v. 34, (22), May 2014, p. 7425-7436
Tang, Jing; Ip, Pak Kan; Ye, Tao; Ng, Yu Pong; Yung, Wing-Ho; Wu, Zhenguo; Fang, Weiqun; Fu, Kit Yu; Ip, Nancy Yuk Yu
Article

Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex

Nature Communications, v. 5, September 2014, article number 4826
Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton

Journal of Neuroscience, v. 34, (7), 2014, p. 2413-2421
Chen, Yuewen; Ip, Fanny Chui Fun; Shi, Lei; Zhang, Zhe; Tang, Huibin; Ng, Yu Pong; Ye, Wen-Cai; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

CRMP2: Functional roles in neural development and therapeutic potential in neurological diseases

Neuroscientist, v. 20, (6), December 2014, p. 589-598
Ip, Jacque P.K.; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice

Cell Reports, v. 9, (5), December 2014, p. 1635-1644
Fang, Wei-Qun; Chen, Wei-Wei; Jiang, Liwen; Liu, Kai; Yung, Wing-Ho; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

p35 Regulates the CRM1-Dependent Nucleocytoplasmic Shuttling of Nuclear Hormone Receptor Coregulator-Interacting Factor 1 (NIF-1)

PLoS ONE, v. 9, (10), October 2014, article number e110584
Zhao, Xiao-Su; Fu, Wing-Yu; Chien, Winnie W.Y.; Li, Zhen; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

老年痴呆症的分子机制

生命科学=Chinese Bulletin of Life Sciences, v. 26, (6), June 2014, p. 550-559
沈陽; 陳宇; 傅潔瑜; 葉玉如
Article

Activity-Dependent Regulation of Liprinα1 During Synapse Development

Huang, Huiqian; Lai, Kwok On; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Axin Regulates Synapse Development in the Hippocampus

Liang, Z.; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Blockade of EphA4 Signaling Alleviates Alzheimer's Disease-associated Impairment of Hippocampal Synaptic Plasticity

Hung, Kwok Wang; Fu, Kit Yu; Huang, Huiqian; Gu, Shuo; Cheng, Yee Ling; Ip, Fanny Chui Fun; Fu, Wing-Yu; Ip, Nancy Yuk-Yu
Conference paper

Blockade of EphA4 Signaling Alleviates the Impairment of Hippocampal Synaptic Plasticity Associated With Alzheimer's Disease

Fu, Amy Kit Yu; Hung, Nelson Kwok Wang; Huang, Huiqian; Gu, S.; Shen, Yang; Cheng, Yee Ling; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-mediated Phosphorylation of RapGEF2 Controls Neuronal Migration in the Developing Cortex

Ye, Tao; Ip, Jacque P.K.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Mediated Phosphorylation of RapGEF2 Controls Neuronal Migration in the Developing Cortex

Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Mediated Phosphorylation of RapGEF2 Is Required for Neuronal Migration During Cerebral Cortex Development

Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Role of Axin in Synapse Development

Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Functional Role of Axin in Synapse Development

Chen, Yu; Liang, Zhuoyi; Fei, Erkang; Fang, Weiqun; Fu, Wing-Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Melanocortin-4 Receptor in Hippocampal Synaptic Plasticity

Shen, Yang; Fu, Ada W.Y.; Cheng, Elaine; Tian, Min; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Identification and Characterization of Small Molecule EphA4 Inhibitors as Disease Modifiers for Alzheimer's Disease

Fu, Ada Wing Yu; Hung, Nelson Kwok Wang; Gu, Shuo; Xu, Junyu; Su, A.; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of Novel EphA4 Inhibitors as a Disease-Modifying Treatment for Alzheimer's Disease

Fu, Wing-Yu; Hung, Nelson Kwok Wang; Gu, Shuo; Xu, Jzajing; Su, Audrey; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor Mediated Regulation of Hippocampal Synaptic Plasticity

Shen, Yang; Fu, Ada Wing Yu; Cheng, Yee Ling; Tian, Min; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a PKA-dependent mechanism

Shen, Yang; Fu, Ada W.Y.; Cheng, Yee Ling; Tian, Min; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Regulation and Functions of Liprinα1 in Activity-dependent Synapse Development

Huang, H.Q.; Lai, Kwok On; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-nitrosylation of Cdk5 and its Activator p35 in Neuronal Morphogenesis and Synaptic Function

Zhang, Peng; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cdk5 and Its Activator p35 in Neuronal Morphogenesis and Synaptic Function

Zhang, Peng; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cyclin-Dependent Kinase 5 and Its Activator p35 Is Crucial for Neuronal Morphogenesis and Synaptic Function

Zhang, Peng; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

The Role of Axin in Dendrite and Spine Development

Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

The Role of Axin in Dendrite and Spine Development

Liang, Zhuoyi; Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada W.Y.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

The Role of Liprinα1 in Activity-Dependent Regulation of Synapse Development

Huang, Huiqian; Lai, K.O.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

2013 7

Axin Directs the Amplification and Differentiation of Intermediate Progenitors in the Developing Cerebral Cortex

Neuron, v. 79, (4), August 2013, p. 665-679
Fang, Weiqun; Chen, Weiwei; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Axin: An emerging key scaffold at the synapse

IUBMB Life, v. 65, (8), August 2013, p. 685-691
Chen, Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk Yu
Article

Cdk5 Phosphorylates a Component of the HDAC Complex and Regulates Histone Acetylation during Neuronal Cell Death

NeuroSignals, v. 21, (1-2), February 2013, p. 55-60
Fu, Kit Yu; Hung, Kwok Wang; Wong, Hovy Ho-Wai; Fu, Wing Yu; Ip, Nancy Y.Y.
Article

Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-Dependent Mechanism

Journal of Neuroscience, v. 33, (2), January 2013, p. 464-472
Shen, Yang; Fu, Wing-Yu; Cheng, Elaine Y.L.; Fu, Amy K.Y.; Ip, Nancy Y.
Article

Axin Regulates Dendrite and Spine Development in Hippocampal Neurons

Chen, Yu; Fei, Erkang; Fang, Weiqun; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-dependent Phosphorylation of Mst3 Regulates Radial Migration through Modulating RhoA Activity

Tang, Jing; Ip, Jacque Pak Kan; Fang, Weiqun; Zhong, Wanting; Ng, Yu Pong; Wu, Zhenguo; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Inhibition of EphA4 Signaling Reverses the Abeta-induced Synaptic Deficits in the Hippocampus

Fu, Amy Kit Yu; Hung, Kwok Wang; Huang, Huiqian; Gu, Shuo; Shen, Yang; Cheng, Elaine; Ip, Fanny Chui Fun; Huang, Xuhui; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

2012 20

Ankyrin repeat-rich membrane spanning protein (Kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development

Journal of Neuroscience, v. 32, (24), June 2012, p. 8263-8269
Chen, Yu; Fu, Ada W.Y.; Ip, Pak Kan; Ye, Tao; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Y.
Article

Cyclin-Dependent Kinase 5 in Axon Growth and Regeneration

International Review of Neurobiology, v. 105, December 2012, p. 91-115
Ye, Tao; Fu, Kit Yu; Ip, Nancy Y.
Article

Eph receptors at synapses: Implications in neurodegenerative diseases

Cellular Signalling, v. 24, (3), March 2012, p. 606-611
Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Molecular mechanisms underlying maturation and maintenance of the vertebrate neuromuscular junction

Trends in Neurosciences, v.35, (7), July 2012, p. 441-453
Shi, Ling; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2

Nature Neuroscience, v.15, (1), January 2012, p. 39-47
Ip, Pak Kan; Shi, Lei; Chen, Yu; Itoh, Yasuhiro; Fu, Wing Yu; Betz, Andrea; Yung, Wing-Ho; Gotoh, Yukiko; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Axin Regulates the Balance Between Proliferation and Neuronal Differentiation of Neural Precursor Cells

Fang, Weiqun; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Dependent Regulation of Rap1 Signaling in Cortical Neuronal Migration

Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of cdk5 in Rap1 Signaling During Neuronal Migration

Ye, Tao; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Mst3 in Radial Migration During Mouse Cerebral Cortex Development

Tang, J.; Ip, J.P.K.; Fang, W.Q.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Mst3 in Radial Migration During the Development of Mouse Cerebral Cortex

Tang, Jing; Ip, Pak Kan; Fang, Weiqun; Zhong, Weiting; Ng, Yu Pong; Wu, Zhenguo; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity

Shen, Yang; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Melanocortin-4 Receptor-Mediated Regulation of Hippocampal Synaptic Plasticity

Shen, Y.; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Nucleocytoplasmic Shuttling of Axin Balances Proliferation and Neuronal Differentiation of Neural Progenitor Cells

Fang, W.Q.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

P39-Associated Cdk5 Activity Regulates Dendrite Development

Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

P39-Associated Cdk5 Activity Regulates Dendrite Growth in Neuronal Development

Fu, Amy Kit Yu; Chen, Yu; Fu, Ada Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Roles of a2-Chimaerin in Neural Circuit Wiring and Function

Fu, Kit Yu; Min, L.; Yung, W.H.; Ip, J.P.K.; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) and Its Activator in Neural Development.

Zhang, Peng; Ip, Pak Kan; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) and Its Activator p35 Regulate Neural Development

Zhang, P.; Ip, J.P.K.; Fu, W.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Α2-Chimaerin Is Required for Proper Functioning of Neural Circuits

Ip, Pak Kan; Yung, Wing Ho; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2011 11

APC^Cdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

Nature Neuroscience, v. 14, (2), February 2011, p. 181-191
Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-yu
Article

Cdk5-Mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development

Journal of Neuroscience, v. 31, (38), September 2011, p. 13613-13624
Fang, Wei-Qun; Ip, Jacque P.K.; Li, Rui; Ng, Yu Pong; Lin, Shengcai; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development

Neuroscience, v.180, April 2011, p. 353-359
Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

Scapinin-induced Inhibition of Axon Elongation Is Attenuated by Phosphorylation and Translocation to the Cytoplasm

Journal of Biological Chemistry, v. 286, (22), June 2011, p. 19724-19734
Farghaian, Hovik; Chen, Yu; Fu, Ada Wing Yu; Fu, Amy Kit Yu; Ip, Pak Kan; Ip, Nancy Yuk-yu; Turnley, Ann M.; Cole, Adam R.
Article

A2-Chimaerin Regulates Crmp-2 Activity to Control Cortical Neuronal Migration

Ip, J.P.; Shi, L.; Itoh, Y.; Fu, Wing Yu; Gotoh, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Axon Formation in Cerebral Cortex Through Phosphorylation of Axin

Fu, Kit Yu; Fang,W-Q; Ip, J.P.; Li, R.; Lin,S-C; Chen, Y.; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Cdk5 signaling in AD

GSK R & D China, China, Shanghai; April, 2011
Fu, Amy K.Y.
Conference paper

EphB Receptor Regulates Glutamatergic Synaptogenesis Through a Cdk5-Dependent Mechanism

Chen, Y.; Wong, H.; Fu, WY; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Melanocortin-4 Receptor in Synapse Maintenance

Shen, Y.; Fu, Kit Yu; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Mst3 in Radial Migration During the Development of Mouse Cerebral Cortex

Tang, J.; Ip, J.P.; Shi, L.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

S-Nitrosylation of Cdk5 Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development

Zhang, P.; Yu,P-C; Tsang, A.H.; Chen, Y.; Fu, Kit Yu; Fu, WY; Chung, Kenny Ka Kin; Ip, Nancy Yuk-Yu
Conference paper

2010 15

Cdk5-Mediated Phosphorylation of delta-Catenin Regulates Its Localization and GluR2-Mediated Synaptic Activity

Journal of Neuroscience, v. 30, (25), June 2010, p. 8457-8467
Poore, Charlene P.; Sundaram, Jeyapriya R.; Pareek, Tej K.; Fu, Amy; Amin, Niranjana; Mohamed, Nur Ezan; Zheng, Ya-Li; Goh, Angeline X.H.; Lai, Mitchell K.; Ip, Nancy Yuk-Yu; Pant, Harish C.; Kesavapany, Sashi
Article

Ephexin1 Is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction

Neuron, v. 65, (2), January 2010, p. 204-216
Shi, Lei; Butt, Busma; Ip, Fanny C.F.; Dai, Ying; Jiang, Liwen; Yung, Wing-Ho; Greenberg, Michael E.; Fu, Amy K.Y.; Ip, Nancy Yuk-Yu
Article

Multiple Roles of the Rho GEF Ephexin1 in Synapse Remodeling

Communicative & Integrative Biology, v. 3, (6), 2010, p. 622-624
Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-yu
Article

S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development

Journal of Neuroscience, v. 30, (43), October 2010, p. 14366-14370
Zhang, Peng; Yu, Peichun; Tsang, Anthony H.K.; Chen, Yu; Fu, Kit Yu; Fu, Wing Yu; Chung, Kenny K.K.; Ip, Nancy Yuk-Yu
Article

Two Cyclin-Dependent Kinase Pathways Are Essential for Polarized Trafficking of Presynaptic Components

Cell, v. 141, (5), May 2010, p. 846-858
Ou, Chan-Yen; Poon, Vivian Y.; Maeder, Celine I.; Watanabe, Shigeki; Lehrman, Emily K.; Fu, Amy K.Y.; Park, Mikyoung; Fu, Wing-Yu; Jorgensen, Erik M.; Ip, Nancy Yuk-Yu; Shen, Kang
Article

Tyk2/STAT3 Signaling Mediates beta-Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease

Journal of Neuroscience, v. 30, (20), May 2010, p. 6873-6881
Wan, Jun; Fu, Kit Yu; Ip, Fanny Chui Fun; Ng, Ho Keung; Hugon, Jacques; Page, Guylène K.; Wang, Jerry Hsueh-ching; Lai, Kwok On; Wu, Zhenguo; Ip, Nancy Yuk-yu
Article

Alpha2-Chimaerin Regulates Neuronal Polarization and Spine Development

Shi, Lei; Ip, Pak Kan; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Arms/Kidins220 Regulates Dendritic Development Through Ephrin and Neurotrophin Signaling

Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

Axin Directs Axon Formation Through Its Interaction With GSK-3beta

Fang, Weiqun; Ip, Pak Kan; Li, Rui; Ng, Yu Pong; Lin, S.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Is a Key Regulator in Dendrite Development

Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5-Dependent Phosphorylation of Axin Is Important for Axon Development

Fang, Weiqun; Ip, Jacque P.K.; Li, Rui; Ng, Yu Pong; Lin, S.C.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Dependent Degradation of AMPA Receptor Is Important for the Homeostatic Synaptic Plasticity

Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Epha4-Dependent Signaling Regulates the Expression of AMPA Receptor in Homeostatic Plasticity

Fu, Kit Yu; Hung,K-W; Fu, Wing Yu; Shen, C.; Chen, Y.; Xia, J.; Lai,K-O; Ip, Nancy Yuk-Yu
Conference paper

Regulation of Cyclin-Dependent Kinase-5 Activity by S-Nitrosylation

Fu, Wing Yu; Zhang, Peng; Tsang, Anthony H.K.; Xie, S.Y.; Fu, Kit Yu; Chung, Kenny K K; Ip, Nancy Yuk-Yu
Conference paper

Α2-Chimaerin Regulates Laminar Positioning in the Cerebral Cortex

Ip, Jacque P.K.; Shi, Lei; Itoh, Y.; Fu, Wing Yu; Gotoh, Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2009 8

Axin Plays an Essential Role in Neuronal Polarization

Fang, Weiqun; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Axin Plays an Essential Role in Neuronal Polarization

Fang, Weiqun; Lin, S.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdh1 Is Required for Synapse Development and Function

Fu, Wing Yu; Hung, Kwok Wang; Shi, Lei; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdh1-Dependent Degradation of Postsynaptic Proteins Is Important for Synapse Development and Functions

Fu, Wing Yu; Hung, Kwok Wang; Shi, Lei; Lai, Kwok On; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates the Histone Acetylation During Neuronal Apoptosis

Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cyclin Dependent Kinase 5 Phosphorylation of Delta-Catenin Mediates Its Subcellular Localisation in Neurons

Poore, C.P.; Sundram, J.R.; Pareek, T.K.; Fu, Kit Yu; Ip, Nancy Yuk-Yu; Pant, H.C.; Kesavapany, S.
Conference paper

EphA4-Mediated Degradation of AMPA Receptor Is Important in Homeostatic Synaptic Plasticity

Fu, Kit Yu; Hung, Kwok Wang; Fu, Wing Yu; Shen, Chong; Chen, Yu; Xia, Jun; Lai, Kwok On; Ip, Nancy Yuk-Yu
Conference paper

Ephexin1 Promotes Postsynaptic Maturation at the Neuromuscular Junction

Shi, Lei; Butt, Busma Wai Yin; Ip, Fanny C.F.; Dai, Ying; Greenberg, M.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2008 9

Bidirectional signaling of ErbB and Eph receptors at synapses

Neuron Glia Biology, v. 4, (3), August 2008, p. 211-221
Chen, Yu; Fu, Kit Yu; Ip, Nancy Y.
Article

β-catenin in reverse action

Nature Neuroscience, v. 11, (3), 2008, p. 244-246
Fu, Kit Yu; Cheung, Zelda H.; Ip, Nancy Yuk-Yu
Article

A Transcriptional Regulator NIF-1 Regulates Neurite Outgrowth and Undergoes p35-Dependent Nuclear Export

Zhao, Xiao Su; Fu, Wing Yu; Chien, Winnie W.Y.; Li, Zhen; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Dendritic Development in Hippocampal Neurons

Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Signaling Regulates the Dispersal of Acetylcholine Receptors Through Activation of ephexin1

Shi, L.; Butt, B.; Greenberg, M.E.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Signaling Regulates the Stability of Agrin-Induced Acetylcholine Receptors Through Activation of Ephexin1

Shi, Lei; Butt, Busma Wai Yin; Greenberg, Michael E.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Dependent Signaling Regulates the Synaptic Strength of Glutamatergic Synapses

Fu, Kit Yu; Hung, K.W.; Shen, C.; Xia, J.; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Nucleocytoplasmic shuttling of p35 regulates functions of NIF-1 in neurite outgrowth

International Meeting for Asian Young Reseachers, Japan, 27-28 Feb 08
Fu, Amy K.Y.
Conference paper

2007 5

alpha 2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse

Proceedings of the National Academy of Sciences of the United States of America, v. 104, (41), October 2007, p. 16347-16352
Shi, Lei; Fu, Wing Yu; Hung, Kwok Wang; Porchetta, Cassandra; Hall, Christine; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism

Nature Neuroscience, v. 10, (1), January 2007, p. 67-76
Fu, Wing Yu; Chen, Yu; Sahin, Mustafa; Zhao, Xiao-Su; Shi, Lei; Bikoff, Jay B.; Lai, Kwok-On; Yung, Wing-Ho; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Article

Cyclin-dependent kinase 5 links extracellular cues to actin cytoskeleton during dendritic spine development

Cell Adhesion & Migration, v. 1, (2), April 2007
Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Expression of G protein beta subunits in rat skeletal muscle after nerve injury: Implication in the regulation of neuregulin signaling

Neuroscience, v. 146, (2), May 2007, p. 594-603
Lok, Ka Chun; Fu, Amy Kit Yu; Ip, Fanny Chun Fun; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Article

NRG induces membrane targeting of Gαz in muscle: implication in myogenesis

NeuroReport, v. 18, (14), September 2007, p. 1433-1436
Lok, Ka Chun; Fu, Kit Yu; Ip, Fanny C.F.; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Article

2006 13

Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein - Implications in the regulation of its hexamerization and exocytosis

Journal of Biological Chemistry, v. 281, (15), April 2006, p. 9852-9858
Liu, Yuxin; Cheng, Kai; Gong, Ke; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Synaptic roles of Cdk5: Implications in higher cognitive functions and neurodegenerative diseases

Neuron, v. 50, (1), April 2006, p. 13-18
Cheung, Zelda H.; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

ANKRA2 Interacts With p35 and Regulates Gene Transcription

Ng, Alberto K.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

ARMS Regulates Dendritic Development in Hippocampal Neurons

Chen, Yu; Fu, Wing Yu; Fu, Kit Yu; Chao, Moses V.; Ip, Nancy Yuk-Yu
Conference paper

Axin Is Involved in Nerve Growth Factor-Induced Differentiation of PC12 Cells

Ng, Yu Pong; Lin, Shengcai; Fu, Kit Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Cdk5 Regulates Mitochondrial Function Through a Cdk5RAP1-Dependent Mechanism

Wong, Grace K.W.; Fu, Kit Yu; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Induces Dendritic Spine Retraction Through a Cdk5-Dependent Mechanism

Fu, Wing Yu; Chen, Yu; Sahin, Mustafa; Zhao, Xiaosu; Shi, Lei; Bikoff, Jay B.; Lai, Kwok On; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Conference paper

EphA4 Induces Dendritic Spine Retraction Through a Cdk5-ephexin1-Dependent Mechanism

Fu, Wing Yu; Chen, Yu; Sahin, Mustafa; Zhao, Xiao Su; Shi, Lei; Bikoff, Jay B.; Lai, Kwok On; Yung, Wing Ho; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Mediated Signaling Regulates the Aggregation of AChRs Stimulated by Agrin

Shi, Lei; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

EphA4-Mediated Signaling Regulates the Agrin-Stimulated Aggregation of AChRs in C2C12 Myotubes

Shi, Lei; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

NRC-Interacting Factor 1 (NIF-1) Associates With p35 and Is Involved in Neuronal Differentiation

Zhao, Xiao Su; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Role of Axin in Nerve Growth Factor-Induced Differentiation of PC12 Cells

Ng, Yu Pong; Lin, Shengcai; Fu, Kit Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

2005 10

Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice

Proceedings of the National Academy of Sciences of the United States of America, v. 102, (42), October 2005, p. 15224-15229
Fu, Amy Kit Yu; Ip, Fanny Chun Fun; Fu, Wing Yu; Cheung, Janet; Wang, Jerry H.; Yung, Wing-Ho; Ip, Nancy Yuk-Yu
Article

Agrin regulates growth cone turning of Xenopus spinal motoneurons

Development, v. 132, (19), October 2005, p. 4309-4316
Xu, Xiaohua; Fu, Amy Kit Yu; Ip, Fanny Chun Fun; Wu, Chien-ping; Duan, Shumin; Poo, Mu-ming; Yuan, Xiao-bing; Ip, Nancy Yuk-Yu
Article

Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex

Journal of Neuroscience, v. 25, (20), May 2005, p. 4979-4984
Gu, Zhenglin; Jiang, Qian; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu; Yan, Zhen
Article

ANKRA Interacts With p35 and Is a Substrate for Cdk5/p35

Ng, Alberto K.Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cyclin-Dependent Kinase 5 Regulates EphA4-Mediated Signaling and Post-Synaptic Specialization

Fu, Wing Yu; Sahin, Mustafa; Shi, Lei; Chen, Yu; Lai, Kwok On; Fu, Kit Yu; Greenberg, Michael E.; Ip, Nancy Yuk-Yu
Conference paper

Cyclin-Dependent Kinase 5 Regulates the Development of Motor Axons and AChR Clustering at Neuromuscular Synapses

Fu, Kit Yu; Ip, Fanny C.F.; Cheung, Janet H.N.; Wang, Jerry Hsueh-ching; Yung, Wing Ho; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Axin in the Formation of Neuromuscular Junction

Lu, Cheney C.; Fu, Kit Yu; Ng, Yu Pong; Lin, Shengcai; Ip, Nancy Yuk-Yu
Conference paper

Identification of Anaphase Promoting Complex Subunit 2 Isoform as EphA4 Interacting Protein

Hung, Kwok Wang; Shen, Winnie Y.; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Pctaire1 Phosphorylates N-Ethylmaleimide Sensitive Fusion Protein and Regulates Constitutive Exocytosis in PC12 Cells

Liu, Yuxin; Cheng, Kai; Hung, Kwok Wang; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Role of Axin in Nerve Growth Factor-Stimulated Neurite Outgrowth

Ng, Yu Pong; Lin, Shengcai; Fu, Wing Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

2004 11

Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription

Journal of Biological Chemistry, v. 279, (52), December 2004, p. 54438-54444
Li, Zhen; David, Gregory; Hung, Kwok Wang; Depinho, Ronald A.; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity

Proceedings of the National Academy of Sciences of the United States of America, v. 101, (17), April 2004, p. 6728-6733
Fu, Amy Kit Yu; Fu, Wing Yu; Ng, Alberto K. Y.; Chien, Winnie W. Y.; Ng, Yu Pong; Wang, Jerry H.; Ip, Nancy Yuk-Yu
Article

Cdk5 Phosphorylation of STAT3 Regulates Its Transcriptional Activity in Neuregulin-ErbB Signaling

Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Cyclin-Dependent Kinase 5 Phosphorylates STAT3 and Regulates Its Transcriptional Activity

Journal of Neurochemistry, v. 88, February 2004, p. 18
Fu, Kit Yu; Fu, Wing Yu; Ng, Alberto K.Y.; Chien, Winnie W.Y.; Ng, Yu Pong; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Identification of Endophilin B1 as a p35-Interacting Protein

Cheung, Anthony Y.H.; Fu, Wing Yu; Li, Zhen; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Identification of mSds3, a Component of Transcriptional Repressor Complex, as a Novel p35-Interacting Protein

Fu, Kit Yu; Li, Zhen; David, G.; Hung, Kwok Wang; Depinho, R.A.; Ip, Nancy Yuk-Yu
Conference paper

Identification of N-Ethylmaleimide-Sensitive Fusion Protein as a pctaire1 Interacting Protein

Liu, Yuxin; Cheng, Kai; Hung, Kwok Wang; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Pctaire1 Regulates the Dendritic Development in Primary CNS Neurons

Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Regulation of STAT3 Activation by NGF During PC12 Neuronal Differentiation

Ng, Yu Pong; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Regulation of STAT3 Signaling in NGF-Induced Neuronal Differentiation

Ng, Yu Pong; Fu, Wing Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Tyrosine Phosphorylation of Cyclin-Dependent Kinase 5 by Activated EphA4 Receptor

Fu, Wing Yu; Lai, Kwok On; Gong, Ke; Chen, Yu; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2003 5

Cdk5 Phosphorylates STAT3 and Regulates Its Transcriptional Activity

Fu, Kit Yu; Ng, Alberto K.Y.; Chien, Winnie W.Y.; Ng, Yu-Pong; Fu, Wing Yu; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Cdk5 During the Formation of the Neuromuscular Junction

Journal of Neurochemistry, v. 87, December 2003, p. 168-168
Fu, Kit Yu; Ip, Fanny C.F.; Cheung, Janet; Wang, Jerry Hsueh-ching; Fu, Wing Yu; Ip, Nancy Yuk-Yu
Conference paper

Pctaire-1 Regulates the Dendritic Development of Cultured Cortical Neurons

Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

Pctaire-1 Regulates the Neurite Outgrowth and Dendritic Development in Primary Cortical Neurons

Fu, Wing Yu; Cheng, Kai; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

The Roles of G-Proteins in the Formation of Neuromuscular Junction and Myogenesis

Lok, Ka Chun; Fu, Wing Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

2002 7

Induction of Cdk5 activity in rat skeletal muscle after nerve injury

NeuroReport, v. 13, (2), February 2002, p. 243-247
Fu, Wing Yu; Fu, Amy Kit Yu; Lok, Ka Chun; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35

Journal of Biological Chemistry, v. 277, (35), August 2002, p. 31988-31993
Cheng, Kai; Li, Zhen; Fu, Wing-Yu; Wang, Jerry H; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Article

Aberrant Development of Neuromuscular Junction in Cdk5 Mutant Mice

Fu, Kit Yu; Ip, Fanny C.F.; Cheung, Janet H.N.; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Conference paper

Agrin-MuSK Signaling Mediates Presynaptic Differentiation

Xu, Xiaohua; Fu, Kit Yu; Yuan, Xiaobing; Jin, Ming; Wu, Chenping; Duan, Shumin; Poo, Mao Ming; Ip, Nancy Yuk-Yu
Conference paper

Involvement of G Protein Signaling Pathway at the Neuromuscular Junctions

Lok, Ka C.; Fu, Wing Yu; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Conference paper

Pctaire1 Interacts With P35 and Is a Novel Substrate for Cdk5/P35

Cheng, Kai; Li, Jenny Z.; Fu, Wing Yu; Wang, Jerry Hsueh-ching; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

The Phosphorylation of Pctaire1 by Cdk5 Regulates Its Activity

Cheng, Kai; Li, Jenny Z.; Fu, Wing Yu; Wang, Jerry Hsueh-ching; Fu, Kit Yu; Ip, Nancy Yuk-Yu
Conference paper

2001 3

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

Nature Neuroscience, v. 4, (4), April 2001, p. 374-381
Fu, Amy Kit Yu; Fu, Wing Yu; Cheung, Janet; Tsim, Karl Wah Keung; Ip, Fanny Chun Fun; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Article

Expression of Eph receptors in skeletal muscle and their localization at the neuromuscular junction

Molecular and Cellular Neuroscience, v. 17, (6), June 2001, p. 1034-1047
Lai, Kwok On; Ip, Fanny Chun Fun; Cheung, Janet; Fu, Amy Kit Yu; Ip, Nancy Yuk-Yu
Article

Overexpression of muscle specific kinase increases the transcription and aggregation of acetylcholine receptors in Xenopus embryos

Molecular Brain Research, v. 96, (1-2), November 2001, p. 21-29
Fu, Amy Kit Yu; Cheung, Janet; Smith, Frances Doneison; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

2000 1

Cloning and characterization of muscle-specific kinase in chicken

Molecular and Cellular Neuroscience, v. 16, (5), November 2000, p. 661-673
Ip, Fanny Chun Fun; Glass, David G.; Gies, David R.; Cheung, Janet; Lai, Kwok On; Fu, Amy Kit Yu; Yancopoulos, George D.; Ip, Nancy Yuk-Yu
Article

1999 3

Identification of genes induced by neuregulin in cultured myotubes

Molecular and Cellular Neuroscience, v. 14, (3), September 1999, p. 241-253
Fu, Amy Kit Yu; Cheung, William M.W.; Ip, Fanny Chun Fun; Ip, Nancy Yuk-Yu
Article

Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development

European Journal of Neuroscience, v. 11, (2), February 1999, p. 373-382
Fu, Amy Kit Yu; Smith, Frances D.; Zhou, Hong; Chu, Apple H.; Tsim, Karl Wah Keung; Peng, Benjamin H.; Ip, Nancy Yuk-Yu
Article

The Cloning and Expression of Xenopus Laevis MuSK That May Be Involved in Synaptogenesis

Smith, F.D.; Chu, A.H.; Zhou, H.; Fu, Kit Yu; Tsim, K.W.K.; Peng, H.B.; Ip, Nancy Yuk-Yu
Conference paper

1998 1

Regulation of Muscle-Specific Kinase (MuSK) During the Formation of Neuromuscular Junction

Ip, F.C.F.; Fu, Kit Yu; Cheung, J.; Ip, Nancy Yuk-Yu
Conference paper

1997 4

Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron-muscle co-cultures

NeuroReport, v. 8, (18), December 1997, p. 3895-3900
Fu, Amy Kit Yu; Ip, Fanny Chun Fai; Lai, Kwok On; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Article

Cloning and Expression of Xenopus MuSK

Chu, A.H.; Smith, F.D.; Ip, F.C.F.; Fu, Kit Yu; Tsim, K.W.K.; Peng, H.B.; Ip, Nancy Yuk-Yu
Conference paper

Identification of Candidate Genes Involved in ARIA Signaling Pathway During the Formation of Neuromuscular Junction Using RAP-PCR

Fu, Kit Yu; Cheung, W.M.W.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Identification of Candidate Genes Involved in the ARIA Signaling Pathway During Synapse Formation

Fu, Kit Yu; Cheung, W.M.W.; Ip, Nancy Yuk-Yu
Conference paper

1996 6

Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury

Journal of Neurochemistry, v. 67, (4), October 1996, p. 1607-1612
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Article

Agrin Induces Phosphorylation of Muscle-Specific Kinase (MuSK) in Myotube Culture

Fu, Kit Yu; Chan, K.M.; Ip, F.C.F.; Valenzuela, D.M.; Glass, D. J. '; Yancopoulos, G.D.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Developmental Expression and Upregulation of Muscle-Specific Kinase (MuSK) in Denervated Skeletal Muscle of the Chick and Rat

Ip, F.C.F.; Fu, Kit Yu; Tsim, K.W.K.; Cheung, J.; Valenzuela, D.M.; Glass, D.J.; Yancopoulos, G.D.; Ip, Nancy Yuk-Yu
Conference paper

Expression of Muscle-Specific Kinase at the Neuromuscular Junction

Ip, F.C.F.; Fu, Kit Yu; Chan, K.M.; Tsim, K.W.K.; Valenzuela, D.M.; Glass, D.J.; Yancopoulos, G.D.; Ip, Nancy Yuk-Yu
Conference paper

Muscle-Specific Kinase (MuSK) Mediates Nerve-Induced Tyrosine Phosphorylation and Aggregation of Acetylcholine Receptors in Neuron-Muscle Co-Cultures.

Fu, Kit Yu; Ip, F.C.F.; Glass, D.J.; Valenzuela, D.M.; Yancopoulos, G.D.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Regulation of Muscle-Specific Kinase (MuSK) During Development and After Nerve Injury

Ip, F.C.F.; Fu, Kit Yu; Lai,K-O; Cheung, J.; Glass, D.J.; Yancopoulos, G.D.; Ip, Nancy Yuk-Yu
Conference paper

1995 5

Cloning of the α component of the chick ciliary neurotrophic factor receptor: Developmental expression and down-regulation in denervated skeletal muscle

Journal of Neurochemistry, v. 65, (6), December 1995, p. 2393-2400
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Article

Developmental Expression and Downregulation of the ? Component of Chick CNTF in Denervated Skeletal Muscle

Ip, F.C.F.; Fu, Kit Yu; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Expression of Neurotrophic Factors and Their Receptors, and Presynaptic Terminal Proteins During the Formation of the Neuromuscular Junctions

Chan, K.M.; Smith, F.D.; Fu, Kit Yu; Tsim, K.W.K.; Ip, F.C.F.; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Neurotrophic Factors During Synaptogenesis in a Neuron-Muscle Co-Culture System

Fu, Kit Yu; Chan, K.M.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

Functional Roles of Neurotrophic Factors on Synapse Formation in a Neuron-Muscle Co-Culture System

Fu, Kit Yu; Lai,K-O; Ip, F.C.F.; Tsim, K.W.K.; Ip, Nancy Yuk-Yu
Conference paper

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